From Malignant Transformation To Metastasis

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From Malignant Transformation to Metastasis

Author : Christian Stock
Publisher : Springer Nature
ISBN 13 : 3030998002
Total Pages : 188 pages
Book Rating : 4.0/5 (39 download)

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Book Synopsis From Malignant Transformation to Metastasis by : Christian Stock

Download or read book From Malignant Transformation to Metastasis written by Christian Stock and published by Springer Nature. This book was released on 2022-04-24 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second book of the three-volume collection "Ion Transport in Tumor Biology" helps readers gain comprehensive knowledge of the pathophysiology of cancer. The authors highlight that ion transport proteins, channels and transporters - collectively referred to as the transportome - are significantly involved in the development and progression of cancer. Nearly 90% of malignant tumor diseases originate from epithelial cells, the function of which, for the most part, is based on the transportome. This volume focuses on molecular principles by showing that dysregulated expression and/or function of ion transporters have been correlated with malignancy in the vast majority of tumor diseases. Within the story of the various chapters, the authors line out various malfunctions of the transportome and where they can be found at different stages of the metastatic cascade. The authors describe how the interactions between the tumor cells' transportome and the environment reinforce mesenchymal behaviour of cancer cells and contribute to their uncontrolled proliferation, migration, invasion, intra- and extravasation up to the formation of metastases. As part of a three-volume collection, this book will fascinate members of the active research community, as well as clinicians from the cancer field.

Transportome Malfunction in the Cancer Spectrum

Author : Christian Stock
Publisher : Springer
ISBN 13 : 9783030909222
Total Pages : 0 pages
Book Rating : 4.9/5 (92 download)

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Book Synopsis Transportome Malfunction in the Cancer Spectrum by : Christian Stock

Download or read book Transportome Malfunction in the Cancer Spectrum written by Christian Stock and published by Springer. This book was released on 2022-12-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first of three volumes in the "Ion Channels & Transporters in Tumor Biology" collection, which discusses the function of ion transport proteins in cellular and systemic homeostasis. The authors highlight the role of the so-called transportome, which is defined by the entirety of ion transporters and ion channels. Thereby, readers will get a better understanding of the impact dysregulated ion transport has on the whole spectrum of cancer types. Cancers display deficiencies in several, sometimes interdependent members of the transportome. Clinicians will be interested in the fact that controlled expression of ion transport proteins dramatically impacts the life span of cancer patients, as shown in recent studies. These observations offer a promising outlook for biomedical scientists, as members of the transportome could be the tumor markers of tomorrow - both for diagnostic and therapeutic purposes. As part of a three-volume collection, this book will fascinate members of the active research community, as well as clinicians from the cancer field.

Comparative Oncology

Author : Alecsandru Ioan Baba
Publisher :
ISBN 13 : 9789732714577
Total Pages : 787 pages
Book Rating : 4.7/5 (145 download)

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Book Synopsis Comparative Oncology by : Alecsandru Ioan Baba

Download or read book Comparative Oncology written by Alecsandru Ioan Baba and published by . This book was released on 2007 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Holland-Frei Cancer Medicine

Author : Robert C. Bast, Jr.
Publisher : John Wiley & Sons
ISBN 13 : 111900084X
Total Pages : 2004 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.

Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Malignant Transformation by Viruses

Author : Werner H. Kirsten
Publisher : Springer Science & Business Media
ISBN 13 : 3642874029
Total Pages : 189 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Malignant Transformation by Viruses by : Werner H. Kirsten

Download or read book Malignant Transformation by Viruses written by Werner H. Kirsten and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: The position of "Cancer Teaching Coordinator" at The University of Chicago has been a consistently rewarding one because of the enthusiasm and support of the faculty and the students. This volume is the result of the second of two recent intensive teach ing sessions which have been planned and implemented by the group which forms the Cancer Coordinator's Advisory Committee. The first of these teaching sessions was held in early March of 1964 and was entitled "LEUKEMIA, A Current and Forward Look. " It attracted overflow attendance from the students and staff of this medical institution augmented by members of the other medical centers in Chicago. It was a stimulating and instructive colloquium, and the only regret we heard expressed afterward was that we had not arranged for publication of the many excellent presentations. One of the events commemorating the seventy-fifth anniversary of the founding of The University of Chicago was this symposium on malignant transformations. This time the Committee advised us to plan on speedy publication, and, logically, it chose Dr. Werner Kirsten, a member of our faculty and an active and effective investigator in this general field of endeavor, to serve as editor of the volume. Again, two of the same ingredients for effective instruction were blended: an excellent group of scientists presenting their latest work and a fine, attentive audience of students and staff.

Malignant Transformation by Viruses

Author :
Publisher :
ISBN 13 :
Total Pages : 177 pages
Book Rating : 4.:/5 (779 download)

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Book Synopsis Malignant Transformation by Viruses by :

Download or read book Malignant Transformation by Viruses written by and published by . This book was released on 1966 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Essentials of Glycobiology

Author : Ajit Varki
Publisher : CSHL Press
ISBN 13 : 9780879696818
Total Pages : 694 pages
Book Rating : 4.6/5 (968 download)

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Book Synopsis Essentials of Glycobiology by : Ajit Varki

Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

Cell Surface Alteration as a Result of Malignant Transformation ...

Author :
Publisher : Ardent Media
ISBN 13 : 9780842270557
Total Pages : 194 pages
Book Rating : 4.2/5 (75 download)

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Book Synopsis Cell Surface Alteration as a Result of Malignant Transformation ... by :

Download or read book Cell Surface Alteration as a Result of Malignant Transformation ... written by and published by Ardent Media. This book was released on 1972 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Malignant Transformation by Viruses

Author : Werner H. Kirsten
Publisher :
ISBN 13 : 9783642874031
Total Pages : 192 pages
Book Rating : 4.8/5 (74 download)

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Book Synopsis Malignant Transformation by Viruses by : Werner H. Kirsten

Download or read book Malignant Transformation by Viruses written by Werner H. Kirsten and published by . This book was released on 2014-01-15 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Environmental Factors, Genes, and the Development of Human Cancers

Author : Deodutta Roy
Publisher : Springer Science & Business Media
ISBN 13 : 1441967524
Total Pages : 521 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Environmental Factors, Genes, and the Development of Human Cancers by : Deodutta Roy

Download or read book Environmental Factors, Genes, and the Development of Human Cancers written by Deodutta Roy and published by Springer Science & Business Media. This book was released on 2010-09-11 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a complex disease. Only 5-10% of human cancers are hereditary in nature. Many of us think of environmental agents when we think of carcinogens. The environment includes all that surrounds us, and environmental influences include not only chemical, physical and biological toxicants, but also diet and lifestyle. In this broadest sense, the environment contributes substantially in the development of human cancer. This book will describe how environment contributes to malignant transformation leading to profound changes in the genetic and signaling networks that control the functioning of the cell. It will critically discuss the understanding of the effects of environment on the development, progression and metastasis of cancer with current knowledge of the signaling networks that support functioning of transformed human cells. Genes and environmental factors that influence the origins of cancer are not necessarily the same as those that contribute to its progression and metastasis. Susceptibility gene variants for each specific cancer are being identified with emerging evidence of gene–environment interaction. Gene-environment interactions will be discussed through each specific cancer-based approach to address the question of how genetic variations can influence susceptibility to the individual type of cancer. It will also highlight and summarize epigenetic changes that increase the risk for susceptibility to a particular type of cancer, particularly in the presence of specific environmental factors. Thus, this book will contain chapters from the world’s experts focused on the current evidences that support the role of environment in the cancer etiology and in the growth of malignant lesions, and discuss who may be susceptible to environmental influences.

Surgical Pathology

Author : Ahmad Altaleb
Publisher : Springer Nature
ISBN 13 : 3030536904
Total Pages : 152 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Surgical Pathology by : Ahmad Altaleb

Download or read book Surgical Pathology written by Ahmad Altaleb and published by Springer Nature. This book was released on 2020-10-19 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a practical and clinically oriented guide to the concepts of pathologic diagnosis of surgical specimens. Concise and highly illustrated chapters cover essential information required within patient management. Telepathology, ancillary techniques, and surgical oncology concepts are also examined. Surgical Pathology: A Practical Guide aims to bridge the knowledge gap between surgeons and pathologists to promote mutual understanding and a better working relationship. This book is relevant to general surgeons, and surgical oncologists, whether in training or in practice. It also serves as an introduction for first-year pathology residents, and medical students interested in surgical pathology.

Mammary Tumor Cell Cycle, Differentiation, and Metastasis

Author : Robert B. Dickson
Publisher : Springer Science & Business Media
ISBN 13 : 1461312590
Total Pages : 432 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Mammary Tumor Cell Cycle, Differentiation, and Metastasis by : Robert B. Dickson

Download or read book Mammary Tumor Cell Cycle, Differentiation, and Metastasis written by Robert B. Dickson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mammary Tumor Cell Cycle, Differentiation and Metastasis is the fifth volume since 1988 in a series designed to broadly examine current advances in the cellular and molecular biology of breast cancer. As in previous volumes, the editors have invited recognized experts in cutting-edge topics to provide a chapter focused on their area of research. The editors have turned to the researchers who study rodent models of the disease and to those who study the cellular and molecular basis of human breast cancer. The first section of the book is devoted to new mouse models of mammary development and tumorigenesis. The second section moves to studies of human breast cancer and focuses on receptors, signalling, and the cell cycle. The final section deals with defective tissue interactions in human breast cancer. We are now in a period of extremely rapid accumulation of data on the molecular and cellular biology of breast cancer. These findings are highlighted in chapters from Mammary Tumor Cell Cycle, Differentiation and Metastasis: Advances in Cellular and Molecular Biology of Breast Cancer.

Frontiers of Engineering

Author : National Academy of Engineering
Publisher : National Academies Press
ISBN 13 : 030945039X
Total Pages : 145 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Frontiers of Engineering by : National Academy of Engineering

Download or read book Frontiers of Engineering written by National Academy of Engineering and published by National Academies Press. This book was released on 2017-01-30 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents papers on the topics covered at the National Academy of Engineering's 2016 US Frontiers of Engineering Symposium. Every year the symposium brings together 100 outstanding young leaders in engineering to share their cutting-edge research and innovations in selected areas. The 2016 symposium was held September 19-21 at the Arnold and Mabel Beckman Center in Irvine, California. The intent of this book is to convey the excitement of this unique meeting and to highlight innovative developments in engineering research and technical work.

Hyaluronan in Cancer Biology

Author : Robert Stern
Publisher : Academic Press
ISBN 13 : 0080921086
Total Pages : 467 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Hyaluronan in Cancer Biology by : Robert Stern

Download or read book Hyaluronan in Cancer Biology written by Robert Stern and published by Academic Press. This book was released on 2009-03-07 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hyaluronan biology is being recognized as an important regulator of cancer progression. Paradoxically, both hyaluronan (HA) and hyaluronidases, the enzymes that eliminate HA, have also been correlated with cancer progression. Hyaluronan, a long-chain polymer of the extracellular matrix, opens up tissue spaces through which cancer cells move and metastasize. It also confers motility upon cells through interactions of cell-surface HA with the cytoskeleton. Embryonic cells in the process of movement and proliferation use the same strategy. It is an example of how cancer cells have commandeered normal cellular processes for their own survival and spread. There are also parallels between cancer and wound healing, cancer occasionally being defined as a wound that does not heal. The growing body of literature regarding this topic has recently progressed from describing the association of hyaluronan and hyaluronidase expression associated with different cancers, to understanding the mechanisms that drive tumor cell activation, proliferation, drug resistance, etc. No one source, however, discusses hyaluronan synthesis and catabolism, as well as the factors that regulate the balance. This book will offer a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer. Offers a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer Chapters are written by the leading international authorities on this subject, from laboratories that focus on the investigation of hyaluronan in cancer initiation, progression, and dissemination Focuses on understanding the mechanisms that drive tumor cell activation, proliferation, and drug resistance

Metastatic Cancer: Clinical and Biological Perspectives

Author : Rahul Jandial
Publisher : CRC Press
ISBN 13 : 9781587066597
Total Pages : 312 pages
Book Rating : 4.0/5 (665 download)

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Book Synopsis Metastatic Cancer: Clinical and Biological Perspectives by : Rahul Jandial

Download or read book Metastatic Cancer: Clinical and Biological Perspectives written by Rahul Jandial and published by CRC Press. This book was released on 2013-08-08 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most cancer deaths are a result of metastasis. The spread of a primary tumor to colonize neighboring and distant organs is the relentless endgame that defines the neoplastic process. Patients who have been diagnosed with cancer are treated to prevent both the recurrence of the tumor at the site of origin and metastasis that would re-stage them as advanced stage IV cancer. Historically and still with some types of cancer, stage IV is perceived by patients as “terminal.” Fortunately, recent molecular therapies have extended the lives of patients with advanced cancer and reassuringly people living with metastatic disease increasingly visit our clinics. What is the path forward? Given that the consilience of science and medicine is a dynamic art from which therapies arise, it would be misguided to consider any single work adequate at capturing the horizon for research. So with humility we constructed this text as primer for scientists. It begins with a broad introduction to the clinical management of common cancers. This is intended to serve as a foundation for investigators to consider when developing basic science hypotheses. Unquestionably, medical and surgical care of cancer patients reveals biology and dictates how novel therapeutics will ultimately be evaluated in clinical trials. The second section of this text offers provocative and evolving insights that underscore the breadth of science involved in the elucidation of cancer metastasis biology. The text concludes with information that integrates scientific and clinical foundations to highlight translational research. This book serves as a framework for scientists to conceptualize clinical and translational knowledge on the complexity of disease that is metastatic cancer.

Pulmonary Metastasis

Author : Leonard Weiss
Publisher : Macmillan Reference USA
ISBN 13 :
Total Pages : 362 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Pulmonary Metastasis by : Leonard Weiss

Download or read book Pulmonary Metastasis written by Leonard Weiss and published by Macmillan Reference USA. This book was released on 1978 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Melanoma

Author : Mandi Murph
Publisher : BoD – Books on Demand
ISBN 13 : 9535120360
Total Pages : 414 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Melanoma by : Mandi Murph

Download or read book Melanoma written by Mandi Murph and published by BoD – Books on Demand. This book was released on 2015-04-01 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Melanoma - Current Clinical Management and Future Therapeutics serves as an advanced course in melanoma or an addendum to further polish expertise. Sections of the book include a thorough introduction on epidemiology and disease, the current surgical management of melanoma and lymph node dissection, immunotherapy along with drug toxicities and emerging research topics, like RAGE and autotaxin, that have potential therapeutic applications. The chapters in this book explore the most common subtype of melanoma, cutaneous disease, as well as a rare form, acral lentiginous melanoma and even canine tumors. Experts from around the globe contributed chapters, most of which have visual illustrations to depict aspects of disease management and therapy, allowing readers to grasp the advanced concepts presented.