Free Radicals in Diagnostic Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 1461518334
Total Pages : 461 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Free Radicals in Diagnostic Medicine by : Donald Armstrong

Download or read book Free Radicals in Diagnostic Medicine written by Donald Armstrong and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: An International Syaposiua on Free Radicals in Diagnostic Medicine was co-sponsored by the state University of New York at Buffalo, Roswell Park Cancer Institute, and the Upstate NY Section of the American Association of Clinical Chemistry. The theme was "A Systems Approach To Laboratory Technology, Clinical Correlations And Antioxidant Therapy." The symposium was held on October 7-8, 1993 at the Hyatt Hotel and on October 9 at Roswell Park Cancer Institute, Buffalo, New York. This proceedings volume contains chapters from platform presentations, poster sessions and from invited special lectures in the areas of basic science, clinical applications and efficacy of treatment. A Special Lecture on the relevance of free radical analysis to clinical medicine was presented by Professor Kunio Yagi of Japan. The Yagi procedure to measure thiobarbituric acid (TBA) reaction reflects the amount of reactive substances, lipid peroxides and aldehydes, in the sample. For example, normal subjects will have less than 4 nmol/ml of serum lipid peroxides, while a person with diabetes generally has equal or greater than 5.0 and a diabetic person with vascular complications often exceeds 7.5 nmol/ml. Serum TBA is a clinically important measure that relates to aging, gender and estrogen as an antioxidant, in the prognosis for vascular disorders, and in pathological conditions relative to the amount of lipid peroxidation. The BASIC SCIENCES portion of the program examined: "Mechanisms of Action, Pathophysiology and Laboratory Tests" in six presentations.

Free Radicals in Biology and Medicine

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Author :
Publisher : OUP Oxford
ISBN 13 : 0191026980
Total Pages : 896 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis Free Radicals in Biology and Medicine by : Barry Halliwell

Download or read book Free Radicals in Biology and Medicine written by Barry Halliwell and published by OUP Oxford. This book was released on 2015-08-21 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt: Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research. Now in its fifth edition, the book has been comprehensively rewritten and updated whilst maintaining the clarity of its predecessors. Two new chapters discuss 'in vivo' and 'dietary' antioxidants, the first emphasising the role of peroxiredoxins and integrated defence mechanisms which allow useful roles for ROS, and the second containing new information on the role of fruits, vegetables, and vitamins in health and disease. This new edition also contains expanded coverage of the mechanisms of oxidative damage to lipids, DNA, and proteins (and the repair of such damage), and the roles played by reactive species in signal transduction, cell survival, death, human reproduction, defence mechanisms of animals and plants against pathogens, and other important biological events. The methodologies available to measure reactive species and oxidative damage (and their potential pitfalls) have been fully updated, as have the topics of phagocyte ROS production, NADPH oxidase enzymes, and toxicology. There is a detailed and critical evaluation of the role of free radicals and other reactive species in human diseases, especially cancer, cardiovascular, chronic inflammatory and neurodegenerative diseases. New aspects of ageing are discussed in the context of the free radical theory of ageing. This book is recommended as a comprehensive introduction to the field for students, educators, clinicians, and researchers. It will also be an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.

Free Radicals in Medicine

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Publisher : Nova Publishers
ISBN 13 : 9781560728696
Total Pages : 210 pages
Book Rating : 4.7/5 (286 download)

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Book Synopsis Free Radicals in Medicine by : Radu Olinescu

Download or read book Free Radicals in Medicine written by Radu Olinescu and published by Nova Publishers. This book was released on 2002 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: The role of reactive oxygen species and other free radicals in normal and disease processes has become a major area of interest in the medical scientific community. In the past 30 years, this area of study has advanced from outright rejection, to general acceptance, to intense study. While there is still some dispute as to the exact role of these highly reactive molecules in pathology, it is clear that they are present in and influence many biological processes. This book provides an overview of the possible biological effects of reactive oxygen species and other free radicals with an emphasis on pathology. The various types of free radicals that may affect the body are discussed along with the potential sources of free radicals, both internal and external to the body. The extensive defenses the body raises against the effects of these molecules in the form of enzymatic and non-enzymatic antioxidants is reviewed. A variety of conditions in which free radicals have been proposed to play a role are discussed. These include the physiological effects of oxygen stress in aging, exercise, and pregnancy. Pathologic conditions discussed include cancer, liver cirrhosis, respiratory problems, and others.

Free Radical Medicine and Biology

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1789851432
Total Pages : 132 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Free Radical Medicine and Biology by :

Download or read book Free Radical Medicine and Biology written by and published by BoD – Books on Demand. This book was released on 2020-07-15 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although free radicals perform some useful immune functions, they can also damage healthy cells through a process called oxidation. Antioxidants reduce the effect of free radicals by binding together with these harmful molecules, decreasing their destructive power. This book highlights various issues of free radical biology from the perspective of antioxidant defense mechanisms. It also provides useful information on gene modulation, radiation-generated reactive oxygen species-induced apoptosis in cancer, and environmental aspects associated with free radicals’ exposure on living systems.

Free Radicals in Chemistry, Biology and Medicine

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Publisher :
ISBN 13 :
Total Pages : 560 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Free Radicals in Chemistry, Biology and Medicine by : Toshikazu Yoshikawa

Download or read book Free Radicals in Chemistry, Biology and Medicine written by Toshikazu Yoshikawa and published by . This book was released on 2000 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Oxidative Stress: Diagnostic Methods and Applications in Medical Science

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Author :
Publisher : Springer
ISBN 13 : 9811047111
Total Pages : 168 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Oxidative Stress: Diagnostic Methods and Applications in Medical Science by : Pawan Kumar Maurya

Download or read book Oxidative Stress: Diagnostic Methods and Applications in Medical Science written by Pawan Kumar Maurya and published by Springer. This book was released on 2017-10-24 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the importance of oxidative stress, related biomarkers, and its diagnostic methods including bio-analytical and advanced detection systems. Oxidative stress is associated with diminished capacity of a biological system to overcome the overproduction of reactive oxygen species. Since oxidative stress has been suggested as a causative factor in many diseases, its prevention is vital, and there is an urgent need for oxidative stress monitoring using in vitro and in vivo models. Interdisciplinary approaches have lead to the development of various oxidative stress monitoring models for real-world clinical and biomedical applications. The development of such methods requires a broad understanding of biology, chemistry, molecular biology, immunology and microbiology. As such, the book is a valuable resource for students, researchers and clinicians interested in the fundamental as well as applied aspects of oxidative stress associated diseases.

Oxygen Radicals in Biology and Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 1468455680
Total Pages : 1064 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Oxygen Radicals in Biology and Medicine by : Michael Simic

Download or read book Oxygen Radicals in Biology and Medicine written by Michael Simic and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 1064 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on the papers presented at the "Fourth International Congress on Oxygen Radicals (4-ICOR)," held June 27 - July 3, 1987, at the University of California, La Jolla. The chapters deal with the phenomena associated with highly reactive oxygen species (hydroxy, peroxy, alkoxy, aroxy, and superoxide radicals, as well as singlet oxygen) and their peroxidation products (hydrogen peroxide, hydroperoxides, peroxides, and epoxides) as they relate to the fields of chemistry, food technology, nutrition, biology, pharmacology, and medicine. The kinetics, energetics, and mechanistic aspects of the reactions of these species and the interrelationship of oxygen radicals (or any other free radicals) and peroxidized products have been emphasized. Special attention is focused on the mechanisms of the generation of free radicals and peroxy products in biosystems and on the adverse effects of these radicals and products in humans. The topics span the continuum from the simple chemistry of model systems to the complex considerations of clinical medicine. The book also explores the mechanisms of agents that protect against free radicals and peroxy products in vitro and in vivo. These agents include antioxidants used in materials, food antioxidants, physiological antioxidants, and antioxienzymes (SOD, glutathione peroxidase, and catalases). The use of these inhibitors to prevent damage to organs being prepared for transplantation, thereby maintaining the quality of transplanted organs and/or extending their "shelf-life," also is examined.

Lipid Peroxides in Biology and Medicine

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Author :
Publisher : Elsevier
ISBN 13 : 0323153453
Total Pages : 377 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Lipid Peroxides in Biology and Medicine by : Kunio Yagi

Download or read book Lipid Peroxides in Biology and Medicine written by Kunio Yagi and published by Elsevier. This book was released on 2012-12-02 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lipid Peroxides in Biology and Medicine emphasizes the importance of the control of lipid peroxides in the body for the prevention and treatment of degenerative diseases. This book discusses the production of free radicals in vivo from the action of xenobiotics, and comparative aspects of several model lipid peroxidation systems. The lipid peroxidation and membrane alterations in erythrocyte survival, and lipid peroxidations of cholesterol are also deliberated. This text likewise covers the mechanism of protection against membrane peroxidation, lipid peroxides as a cause of vascular diseases, and peroxide-mediated metabolic activation of carcinogens. Other topics include lipid peroxide in aging process and production of ethane and pentane during lipid peroxidation. This publication is valuable to biologists, medical practitioners, and clinicians researching on lipid peroxides.

Advanced Protocols in Oxidative Stress I

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Author :
Publisher : Humana Press
ISBN 13 : 9781617378812
Total Pages : 0 pages
Book Rating : 4.3/5 (788 download)

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Book Synopsis Advanced Protocols in Oxidative Stress I by : Donald Armstrong

Download or read book Advanced Protocols in Oxidative Stress I written by Donald Armstrong and published by Humana Press. This book was released on 2011-01-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protocols books specializing in measuring free radical and antioxidant biomarkers began to be published in 1998. Many of these methods are currently finding use in diagnostic medicine. Advanced Protocols in Oxidative Stress I covers the field of oxidative stress with state-of-the-art technology to utilize in research, contributed by an international panel of experts renowned for developing new procedures and methods. Included are sections on reactive oxygen and nitrogen species techniques, antioxidant technology and application, methods for analyzing gene expression, the exciting new area of oxidative stress and stem cell differentiation and specific biostatistical evaluation of biomarkers. This volume presents the current high-tech methodologies and provides a perspective on the diversity of applications in the ever-emerging field of free radical reactions and antioxidants. Due to the dynamic nature of this topic, this book will be the first of several volumes of Advanced Protocols in Oxidative Stress, all part of the highly successful Methods in Molecular BiologyTM series. As part of the series, the chapters include a brief introduction to the material, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and ensuring replication of technology. Cutting-edge and convenient, Advanced Protocols in Oxidative Stress I is an ideal desk reference for scientists wishing to further this research in this exciting, unique and vital field of study.

Free Radicals and Iron

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Author :
Publisher :
ISBN 13 :
Total Pages : 262 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Free Radicals and Iron by : Martyn C. R. Symons

Download or read book Free Radicals and Iron written by Martyn C. R. Symons and published by . This book was released on 1998 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise monograph describes a variety of important reactions of iron in biological free-radical reactions. It presents both a chemical and a biochemical perspective of the topic, but at the same time unifies ideas where possible. Iron plays a key role in biological life processes, as acatalayst enabling us to use oxygen to generate the heat and chemical energy that drives life. When iron is not properly controlled within the body it can cause damage by making free radicals. The authors present a chemical and biomedical perspective of how reactions of iron complexes and freeradicals may contribute to human health and disease, especially in reactions of oxygen and hydrogen peroxide.

Free Radicals, Antioxidants, Aging and Disease

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Author :
Publisher : American Association for Clinical Chemistry, Incorporated
ISBN 13 :
Total Pages : 404 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Free Radicals, Antioxidants, Aging and Disease by : Joseph A. Knight

Download or read book Free Radicals, Antioxidants, Aging and Disease written by Joseph A. Knight and published by American Association for Clinical Chemistry, Incorporated. This book was released on 1999 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents information from significant peer-reviewed studies showing that increased oxidative stress has an important role in numerous medical disorders. Describes current concepts of life expectancy, the aging process, and the presence of free radicals in biological systems. Explores the relationship between free radical and increased oxidative stress in medical disorders, including atherosclerosis, ischemia/reperfusion injury, pulmonary diseases, liver and kidney disorders, cancer, and neurodegenerative disorders.

Oxidative Stress and Antioxidant Protection

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Publisher : John Wiley & Sons
ISBN 13 : 1118832485
Total Pages : 610 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Oxidative Stress and Antioxidant Protection by : Donald Armstrong

Download or read book Oxidative Stress and Antioxidant Protection written by Donald Armstrong and published by John Wiley & Sons. This book was released on 2016-04-11 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative Stress and Antioxidant Protection: The Science of Free Radical Biology and Disease Oxidative Stress and Antioxidant Protection begins with a historical perspective of pioneers in oxidative stress with an introductory section that explains the basic principles related to oxidative stress in biochemistry and molecular biology, demonstrating both pathways and biomarkers. This section also covers diagnostic imaging and differential diagnostics. The following section covers psychological, physiologic, pharmacologic and pathologic correlates. This section addresses inheritance, gender, nutrition, obesity, family history, behavior modification, natural herbal-botanical products, and supplementation in the treatment of disease. Clinical trials are also summarized for major medical disorders and efficacy of treatment, with particular focus on inflammation, immune response, recycling, disease progression, outcomes and interventions. Each of the chapters describes what biomarker(s) and physiological functions may be relevant to a concept of specific disease and potential alternative therapy. The chapters cover medical terminology, developmental change, effects of aging, senescence, lifespan, and wound healing, and also illustrates cross-over exposure to other fields. The final chapter covers how and when to interpret appropriate data used in entry level biostatistics and epidemiology. Authored and edited by leaders in the field, Oxidative Stress and Antioxidant Protection will be an invaluable resource for students and researchers studying cell biology, molecular biology, and biochemistry, as well professionals in various health science fields.

Free Radicals: from Basic Science to Medicine

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Publisher : Birkhäuser
ISBN 13 : 3034891164
Total Pages : 540 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Free Radicals: from Basic Science to Medicine by : POLI

Download or read book Free Radicals: from Basic Science to Medicine written by POLI and published by Birkhäuser. This book was released on 2013-03-11 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: Free radical-mediated reactions have been well known in chemistry and physical chemistry for many years. Applying this knowledge to living organisms, biochemists have shown that reactive free radicals are formed at many intracellular sites during normal metabolism, and they have started to suggest possible roles in various pathological processes and conditions, for example in radiation damage, in the metabolism of xenobiotics, in carcinogenesis and in metabolic disorders. At present, a large and relevant mass of experimental evidence supports the view that reactive free radicals are involved in the pathogenesis of several diseases and syndromes. This literature has captured the attention and interest of people involved in the biomedical field. Exciting developments in radical research are probable in the near future, establishing a greater interaction between basic science research and medicine. While the task of defining the involvement of free radicals in human pathology is difficult, it is nonetheless extremely important that such interaction be fulfilled as soon as possible. These were the considerations motivating us during the organization of the VI Biennial Meeting of the International Society for Free Radical Research held in Torino, Italy, in June 1992, and also during the preparation of this book. Experts in the various aspects of free radical research were invited to participate in the Torino Meeting and to contribute chapters for this volume.

Oxidants, Antioxidants And Free Radicals

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Publisher : CRC Press
ISBN 13 : 1351426230
Total Pages : 450 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis Oxidants, Antioxidants And Free Radicals by : Steven Baskin

Download or read book Oxidants, Antioxidants And Free Radicals written by Steven Baskin and published by CRC Press. This book was released on 2017-11-01 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume collates articles investigating antioxidant, oxidant and free radical research. It examines the role of such research in health and disease, particulary with respect to developing greater understanding about the many interactions between oxidants and antioxidants, and how such substances may act as natural protectants and /or natural toxicants.

Measuring Oxidants and Oxidative Stress in Biological Systems

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Author :
Publisher : Springer Nature
ISBN 13 : 303047318X
Total Pages : 237 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Measuring Oxidants and Oxidative Stress in Biological Systems by : Lawrence J. Berliner

Download or read book Measuring Oxidants and Oxidative Stress in Biological Systems written by Lawrence J. Berliner and published by Springer Nature. This book was released on 2020-08-08 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the methods of analysis and determination of oxidants and oxidative stress in biological systems. Reviews and protocols on select methods of analysis of ROS, RNS, oxygen, redox status, and oxidative stress in biological systems are described in detail. It is an essential resource for both novices and experts in the field of oxidant and oxidative stress biology.

Oxidative Stress Biomarkers and Antioxidant Protocols

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1592591736
Total Pages : 320 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Oxidative Stress Biomarkers and Antioxidant Protocols by : Donald Armstrong

Download or read book Oxidative Stress Biomarkers and Antioxidant Protocols written by Donald Armstrong and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first protocols book, Free Radical and Antioxidant Protocols (1) was published in late 1998. Sections were divided into three parts, covering selected biochemical techniques for measuring oxidative stress, antioxidant (AOX) activity, and combined applications. In choosing the 40 methods to be included in that book, I realized there were considerably more of equal value than that which we could have presented in a single volume. To produce a comprehensive resource, this book and a third are being compiled to expand coverage of the field. A summary of papers (2) published on this important subject emphasizes the continuing rapid growth in oxidative stress investigations relating to our understanding of biochemical reactions, their relevance to pathophysiological mechanisms, how disease may arise, and how therapeutic intervention may be achieved(3). Although there is some overlap between the categories, the ana- sis shown below illustrates where current studies are concentrated and are almost evenly distributed between free radicals and AOX. Over the last 4 yr, there has been a 55% increase in the number of papers published in the area.

Lipid Peroxidation in Biological Systems

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Author :
Publisher : The American Oil Chemists Society
ISBN 13 : 9780935315189
Total Pages : 272 pages
Book Rating : 4.3/5 (151 download)

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Book Synopsis Lipid Peroxidation in Biological Systems by : Alex Sevanian

Download or read book Lipid Peroxidation in Biological Systems written by Alex Sevanian and published by The American Oil Chemists Society. This book was released on 1988 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: