Free Radical Biomedicine: Principles, Clinical Correlations, and Methodologies

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Publisher : Bentham Science Publishers
ISBN 13 : 1608053229
Total Pages : 343 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Free Radical Biomedicine: Principles, Clinical Correlations, and Methodologies by : Y. Robert Li

Download or read book Free Radical Biomedicine: Principles, Clinical Correlations, and Methodologies written by Y. Robert Li and published by Bentham Science Publishers. This book was released on 2012-03-31 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Free radicals and related reactive species, including reactive oxygen and nitrogen species (ROS/RNS) play a critical role in the pathophysiological processes of various human diseases, including cardiovascular diseases, diabetes and metabolic syndrome, neurological disorders, and cancer among many others. This peer-reviewed E-book covers both the fundamental principles and the recent advances in free radical biomedicine along with in-depth discussions of the clinical correlations. It also provides a thorough coverage of the commonly used methods in free radical and antioxidant research with detailed schematic illustrations as well as succinct descriptions of the procedures. This volume should also be a valuable source of information for readers who wish to gain a sound understanding of the research methodologies in this rapidly evolving field.

Antioxidants in Health and Disease

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Publisher : CRC Press
ISBN 13 : 100021902X
Total Pages : 387 pages
Book Rating : 4.0/5 (2 download)

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Book Synopsis Antioxidants in Health and Disease by : Antonis Zampelas

Download or read book Antioxidants in Health and Disease written by Antonis Zampelas and published by CRC Press. This book was released on 2015-06-09 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antioxidant use in health promotion and disease prevention either through dietary intake or supplementation is controversial. This book reviews the latest evidence-based research in the area, principally through prospective cohort studies and randomized controlled trials. It assesses major dietary antioxidants and discusses their use in diseases such as cancer, diabetes, stroke, coronary heart disease, HIV/AIDS, and neurodegenerative and immune diseases. The use of antioxidants in health is also discussed along with common adverse effects associated with antioxidant use.

Molecular Basis of Oxidative Stress

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Publisher : John Wiley & Sons
ISBN 13 : 1118355873
Total Pages : 730 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Molecular Basis of Oxidative Stress by : Frederick A. Villamena

Download or read book Molecular Basis of Oxidative Stress written by Frederick A. Villamena and published by John Wiley & Sons. This book was released on 2013-06-06 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sets the stage for the development of better diagnostic techniques and therapeutics Featuring contributions from an international team of leading clinicians and biomedical researchers, Molecular Basis of Oxidative Stress reviews the molecular and chemical bases of oxidative stress, describing how oxidative stress can lead to the development of cancer and cardiovascular and neurodegenerative diseases. Moreover, it explains the potential role of free radicals in both the diagnosis and the development of therapeutics to treat disease. Molecular Basis of Oxidative Stress is logically organized, beginning with a comprehensive discussion of the fundamental chemistry of reactive species. Next, the book: Presents new mechanistic insights into how oxidative damage of biomolecules occurs Examines how these oxidative events effect cellular metabolism Investigates the role of oxidative stress in the pathogenesis of cancer, neurodegenerative disease, cardiovascular disease, and cystic fibrosis Explores opportunities to improve the diagnosis of disease and the design of new therapeutic agents Readers will find much novel information, including new radical chemistries and the latest discoveries of how free radicals react with biomolecules. The contributors also present recent findings that help us better understand the initiation of oxidative stress and the mechanisms leading to the pathogenesis of various diseases. Throughout the book, the use of molecular structures helps readers better understand redox chemistry. In addition, plenty of detailed figures illustrate the mechanisms of oxidative stress and disease pathogenesis. Examining everything from the basic chemistry of oxidative stress to the pathogenesis of disease, Molecular Basis of Oxidative Stress will help readers continue to explore the nature of oxidative stress and then use that knowledge to develop new approaches to prevent, detect, and treat a broad range of disease conditions.

Prehypertension and Cardiometabolic Syndrome

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Publisher : Springer
ISBN 13 : 331975310X
Total Pages : 674 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Prehypertension and Cardiometabolic Syndrome by : Reuven Zimlichman

Download or read book Prehypertension and Cardiometabolic Syndrome written by Reuven Zimlichman and published by Springer. This book was released on 2018-12-06 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book sheds new light on the management of patients with borderline cardiovascular risk factors in order to prevent their progression to end organ damage. The book stimulates discussion of this poorly understood condition and lays the groundwork for developing recommendations and guidelines. While the diagnostic and therapeutic approach to full-blown diabetes, hypertension, dyslipidemia and obesity is well defined, there is still a lack of clear understanding and guidelines as far as patients with borderline conditions – especially when multiple – are concerned. Moreover, end-organ damage depends on several factors, including genetic factors, making it difficult to predict its extent. As such, the gradual transition from a healthy subject to one with functional hemodynamic changes, and then one with structurally asymptomatic changes and lastly to overt disease needs further investigation. In order to address these knowledge gaps, the book covers a broad variety of topics, making it a valuable tool for identifying which asymptomatic subjects could profit from being appropriately screened and at what stage. Furthermore it offers insights into better treating these patients to prevent their progression to overt disease. The book appeals to cardiologists, primary care physicians and all those healthcare professional looking to optimize the management of these complex and often undiagnosed cases.

General Methods in Biomarker Research and their Applications

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Publisher : Springer
ISBN 13 : 9789400776951
Total Pages : 0 pages
Book Rating : 4.7/5 (769 download)

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Book Synopsis General Methods in Biomarker Research and their Applications by : Victor R. Preedy

Download or read book General Methods in Biomarker Research and their Applications written by Victor R. Preedy and published by Springer. This book was released on 2015-08-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease. The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics and so on. The chapters are written by national or international experts and specialists.

Encyclopedia of Agriculture and Food Systems

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Publisher : Elsevier
ISBN 13 : 0080931391
Total Pages : 2745 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Encyclopedia of Agriculture and Food Systems by : Neal K. Van Alfen

Download or read book Encyclopedia of Agriculture and Food Systems written by Neal K. Van Alfen and published by Elsevier. This book was released on 2014-07-29 with total page 2745 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Agriculture and Food Systems, Second Edition, Five Volume Set addresses important issues by examining topics of global agriculture and food systems that are key to understanding the challenges we face. Questions it addresses include: Will we be able to produce enough food to meet the increasing dietary needs and wants of the additional two billion people expected to inhabit our planet by 2050? Will we be able to meet the need for so much more food while simultaneously reducing adverse environmental effects of today’s agriculture practices? Will we be able to produce the additional food using less land and water than we use now? These are among the most important challenges that face our planet in the coming decades. The broad themes of food systems and people, agriculture and the environment, the science of agriculture, agricultural products, and agricultural production systems are covered in more than 200 separate chapters of this work. The book provides information that serves as the foundation for discussion of the food and environment challenges of the world. An international group of highly respected authors addresses these issues from a global perspective and provides the background, references, and linkages for further exploration of each of topics of this comprehensive work. Addresses important challenges of sustainability and efficiency from a global perspective. Takes a detailed look at the important issues affecting the agricultural and food industries today. Full colour throughout.

Sirtuin Biology in Medicine

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Publisher : Academic Press
ISBN 13 : 0128141190
Total Pages : 421 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Sirtuin Biology in Medicine by : Kenneth Maiese

Download or read book Sirtuin Biology in Medicine written by Kenneth Maiese and published by Academic Press. This book was released on 2021-03-04 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sirtuin Biology in Medicine: Targeting New Avenues of Care in Development, Aging, and Disease provides a fascinating and in-depth analysis of sirtuins in the body during normal physiology as well during disease highlighting the targeting of sirtuin-controlled pathways for the development of innovative, efficacious, and safe therapeutic strategies for multiple disorders in the body that ultimately can affect lifespan extension. Sirtuins are expressed throughout the body, have broad biological effects, and can significantly impact both cellular survival and longevity during acute and long-term illnesses. These histone deacetylases play an intricate role in the pathology, progression, and treatment of several disease entities ranging from neurodegenerative disorders, cardiovascular disease, immune system dysfunction, reproductive dysfunction, endocrine disorders, gastrointestinal disease, drug dependency, and aging-related disorders. Implementing a translational medicine format, this unique reference highlights novel signaling pathways for sirtuins that promote stem cell proliferation, enhance cellular protection, modulate pathways of apoptosis and autophagy, and extend life span. Each chapter is presented with insightful detail that will be of interest and a comprehensive resource to audiences that include scientists, physicians, pharmaceutical industry experts, nutritionists, and students. - Chapters are authored by internationally recognized experts who discuss the broad role of sirtuins in health and disease - Details the basic and clinical role of sirtuins for the development of new clinical treatments - Summarizes the multidiscipline views and publications for the compelling discipline of sirtuins by covering systems throughout the body - Serves as an important resource for a broad audience of healthcare providers, scientists, drug developers, and students in both clinical and research settings

Measurement of Antioxidant Activity and Capacity

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Publisher : John Wiley & Sons
ISBN 13 : 1119135354
Total Pages : 353 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Measurement of Antioxidant Activity and Capacity by : Resat Apak

Download or read book Measurement of Antioxidant Activity and Capacity written by Resat Apak and published by John Wiley & Sons. This book was released on 2018-02-20 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive reference for assessing the antioxidant potential of foods and essential techniques for developing healthy food products Measurement of Antioxidant Activity and Capacity offers a much-needed resource for assessing the antioxidant potential of food and includes proven approaches for creating healthy food products. With contributions from world-class experts in the field, the text presents the general mechanisms underlying the various assessments, the types of molecules detected, and the key advantages and disadvantages of each method. Both thermodynamic (i.e. efficiency of scavenging reactive species) and kinetic (i.e. rates of hydrogen atom or electron transfer reactions) aspects of available methods are discussed in detail. A thorough description of all available methods provides a basis and rationale for developing standardized antioxidant capacity/activity methods for food and nutraceutical sciences and industries. This text also contains data on new antioxidant measurement techniques including nanotechnological methods in spectroscopy and electrochemistry, as well as on innovative assays combining several principles. Therefore, the comparison of conventional methods versus novel approaches is made possible. This important resource: Offers suggestions for assessing the antioxidant potential of foods and their components Includes strategies for the development of healthy functional food products Contains information for identifying antioxidant activity in the body Presents the pros and cons of the available antioxidant determination methods, and helps in the selection of the most appropriate method Written for researchers and professionals in the nutraceutical and functional food industries,academia and government laboratories, this text includes the most current knowledge in order to form a common language between research groups and to contribute to the solution of critical problems existing for all researchers working in this field.

Oxford Handbook of Ethics of AI

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Publisher : Oxford University Press
ISBN 13 : 0190067411
Total Pages : 1000 pages
Book Rating : 4.1/5 (9 download)

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Book Synopsis Oxford Handbook of Ethics of AI by : Markus D. Dubber

Download or read book Oxford Handbook of Ethics of AI written by Markus D. Dubber and published by Oxford University Press. This book was released on 2020-06-30 with total page 1000 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume tackles a quickly-evolving field of inquiry, mapping the existing discourse as part of a general attempt to place current developments in historical context; at the same time, breaking new ground in taking on novel subjects and pursuing fresh approaches. The term "A.I." is used to refer to a broad range of phenomena, from machine learning and data mining to artificial general intelligence. The recent advent of more sophisticated AI systems, which function with partial or full autonomy and are capable of tasks which require learning and 'intelligence', presents difficult ethical questions, and has drawn concerns from many quarters about individual and societal welfare, democratic decision-making, moral agency, and the prevention of harm. This work ranges from explorations of normative constraints on specific applications of machine learning algorithms today-in everyday medical practice, for instance-to reflections on the (potential) status of AI as a form of consciousness with attendant rights and duties and, more generally still, on the conceptual terms and frameworks necessarily to understand tasks requiring intelligence, whether "human" or "A.I."

The Biopsychosocial Model of Health and Disease

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Publisher : Springer
ISBN 13 : 3030118991
Total Pages : 157 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis The Biopsychosocial Model of Health and Disease by : Derek Bolton

Download or read book The Biopsychosocial Model of Health and Disease written by Derek Bolton and published by Springer. This book was released on 2019-03-28 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book is a systematic update of the philosophical and scientific foundations of the biopsychosocial model of health, disease and healthcare. First proposed by George Engel 40 years ago, the Biopsychosocial Model is much cited in healthcare settings worldwide, but has been increasingly criticised for being vague, lacking in content, and in need of reworking in the light of recent developments. The book confronts the rapid changes to psychological science, neuroscience, healthcare, and philosophy that have occurred since the model was first proposed and addresses key issues such as the model’s scientific basis, clinical utility, and philosophical coherence. The authors conceptualise biology and the psychosocial as in the same ontological space, interlinked by systems of communication-based regulatory control which constitute a new kind of causation. These are distinguished from physical and chemical laws, most clearly because they can break down, thus providing the basis for difference between health and disease. This work offers an urgent update to the model’s scientific and philosophical foundations, providing a new and coherent account of causal interactions between the biological, the psychological and social.

Fundamental Principles of Oxidative Stress in Metabolism and Reproduction

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Publisher : Elsevier
ISBN 13 : 0443188068
Total Pages : 370 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Fundamental Principles of Oxidative Stress in Metabolism and Reproduction by : Faiza Alam

Download or read book Fundamental Principles of Oxidative Stress in Metabolism and Reproduction written by Faiza Alam and published by Elsevier. This book was released on 2024-04-07 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamental Principles of Oxidative Stress in Metabolism and Reproduction: Prevention and Management is a comprehensive resource for anyone needing awareness and recognition of oxidative stress as a basic component of disease to determine the precise treatment plan considering the cause of the disease. It describes the effects of oxidative stress in the human body, the detection of metabolic changes, psychological impact and effect on reproductive outcomes. In addition, it discusses alterations at the cellular level occurring due to oxidative stress along with the genetic aspects involved in its pathogenesis. - Provides a holistic approach to the impact of oxidative stress on various systems - Incorporates recent advances in basic sciences for improvement in oxidative stress leading to better prognosis of metabolic conditions - Summarizes knowledge to detect oxidative stress for improvement of fertility outcomes

Principles and Techniques of Biochemistry and Molecular Biology

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Publisher : Cambridge University Press
ISBN 13 : 0521516358
Total Pages : 769 pages
Book Rating : 4.5/5 (215 download)

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Book Synopsis Principles and Techniques of Biochemistry and Molecular Biology by : Keith Wilson

Download or read book Principles and Techniques of Biochemistry and Molecular Biology written by Keith Wilson and published by Cambridge University Press. This book was released on 2010-03-04 with total page 769 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uniquely integrates the theory and practice of key experimental techniques for bioscience undergraduates. Now includes drug discovery and clinical biochemistry.

Phytochemicals

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Publisher : BoD – Books on Demand
ISBN 13 : 1789843774
Total Pages : 220 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Phytochemicals by : Toshiki Asao

Download or read book Phytochemicals written by Toshiki Asao and published by BoD – Books on Demand. This book was released on 2018-11-07 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytochemicals provides original research work and reviews on the sources of phytochemicals, and their roles in disease prevention, supplementation, and accumulation in fruits and vegetables. The roles of anthocyanin, flavonoids, carotenoids, and taxol are presented in separate chapters. Antioxidative and free radicle scavenging activity of phytochemicals is also discussed. The medicinal properties of Opuntia, soybean, sea buckthorn, and gooseberry are presented in a number of chapters. Supplementation of plant extract with phytochemical properties in broiler meals is discussed in one chapter. The final two chapters include the impact of agricultural practices and novel processing technologies on the accumulation of phytochemicals in fruits and vegetables. This book mainly focuses on medicinal plants and the disease-preventing properties of phytochemicals, which will be a useful resource to the reader.

Energy Research Abstracts

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Publisher :
ISBN 13 :
Total Pages : 442 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Energy Research Abstracts by :

Download or read book Energy Research Abstracts written by and published by . This book was released on 1994-08 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Research Methodology in the Medical and Biological Sciences

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Publisher : Academic Press
ISBN 13 : 0080552897
Total Pages : 510 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Research Methodology in the Medical and Biological Sciences by : Petter Laake

Download or read book Research Methodology in the Medical and Biological Sciences written by Petter Laake and published by Academic Press. This book was released on 2007-11-05 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing easy-to-access information, this unique sourcebook covers the wide range of topics that a researcher must be familiar with in order to become a successful experimental scientist. Perfect for aspiring as well as practicing professionals in the medical and biological sciences it discusses a broad range of topics that are common, yet not traditionally considered part of formal curricula. The information presented also facilitates communication across conventional disciplinary boundaries, in line with the increasingly multidisciplinary nature of modern research projects. - Perfect for students with various professional backgrounds providing a broad scientific perspective - Easily accessible, concise material makes learning about diverse methods achievable in today's fast-paced world

How Tobacco Smoke Causes Disease

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Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1422 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1989 with total page 1422 pages. Available in PDF, EPUB and Kindle. Book excerpt: