Fluoropyrimidines in Cancer Therapy

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1592593372
Total Pages : 331 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Fluoropyrimidines in Cancer Therapy by : Youcef M. Rustum

Download or read book Fluoropyrimidines in Cancer Therapy written by Youcef M. Rustum and published by Springer Science & Business Media. This book was released on 2002-12-02 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading cancer researchers update and review the mechanisms of action and the therapeutic selectivity and efficacy of 5-FU with and without leucovorin and its prodrugs in the treatment of colorectal cancer. Among the combination agents considered are UFT/LV, 5-FU/EU, capecitabine (Xeloda), S-1, and a variety of thymidylate synthase inhibitors. The authors discuss the potential advantages and disadvantages of these varied drugs and their mode of administration. Based on historical results with these agents when used alone, they also present a rationale for their results when used in combination with other agents.

Fluoropyrimidines in Cancer Therapy

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Publisher :
ISBN 13 : 9781468497526
Total Pages : 340 pages
Book Rating : 4.4/5 (975 download)

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Book Synopsis Fluoropyrimidines in Cancer Therapy by : Youcef M. Rustum

Download or read book Fluoropyrimidines in Cancer Therapy written by Youcef M. Rustum and published by . This book was released on 2014-01-15 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fluoropyrimidines in Cancer Therapy

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Publisher :
ISBN 13 :
Total Pages : 563 pages
Book Rating : 4.:/5 (251 download)

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Book Synopsis Fluoropyrimidines in Cancer Therapy by : Kiyoji Kimura

Download or read book Fluoropyrimidines in Cancer Therapy written by Kiyoji Kimura and published by . This book was released on 1984 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Expanding Role of Folates and Fluoropyrimidines in Cancer Chemotherapy

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1468456075
Total Pages : 328 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis The Expanding Role of Folates and Fluoropyrimidines in Cancer Chemotherapy by : Y. Rustum

Download or read book The Expanding Role of Folates and Fluoropyrimidines in Cancer Chemotherapy written by Y. Rustum and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fluoropyrimidines in Cancer Therapy

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Publisher :
ISBN 13 :
Total Pages : 596 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Fluoropyrimidines in Cancer Therapy by : Kiyoji Kimura

Download or read book Fluoropyrimidines in Cancer Therapy written by Kiyoji Kimura and published by . This book was released on 1984 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fluoropyrimidines in cancer therapy

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Author :
Publisher :
ISBN 13 :
Total Pages : 563 pages
Book Rating : 4.:/5 (463 download)

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Book Synopsis Fluoropyrimidines in cancer therapy by : Kiyoji Kimura

Download or read book Fluoropyrimidines in cancer therapy written by Kiyoji Kimura and published by . This book was released on 1984 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Leucovorin Modulation of Fluoropyrimidines

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Publisher :
ISBN 13 :
Total Pages : 140 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Leucovorin Modulation of Fluoropyrimidines by : H. M. Pinedo

Download or read book Leucovorin Modulation of Fluoropyrimidines written by H. M. Pinedo and published by . This book was released on 1989 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Ryan's Retina E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323401988
Total Pages : 2893 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Ryan's Retina E-Book by : Charles P. Wilkinson

Download or read book Ryan's Retina E-Book written by Charles P. Wilkinson and published by Elsevier Health Sciences. This book was released on 2017-04-17 with total page 2893 pages. Available in PDF, EPUB and Kindle. Book excerpt: The undisputed gold standard text in the field, Ryan's Retina is your award-winning choice for the most current, authoritative information on new technologies, surgical approaches, scientific advances and diagnostic and therapeutic options for retinal diseases and disorders. Packed with timely updates throughout, new illustrations, and a dedicated team of editors who extend Dr. Ryan’s legacy in retina, this outstanding 6th Edition is a must-have reference for retinal specialists, ophthalmologists, and fellows in training. Offers the most comprehensive content available on retina, balancing the latest scientific research and clinical correlations, covering everything you need to know on retinal diagnosis, treatment, development, structure, function, and pathophysiology. Provides a truly global perspective from five highly esteemed section editors and more than 350 other world authorities from across Europe, Asia, Australasia, and the Americas. Bullets Includes new chapters on widefield imaging, intraoperative OCT imaging, medical management of diabetes mellitus and age-related macular degeneration, and senile retinoschisis. Includes more than 1,150 brand-new illustrations, scans, and photographs throughout. Covers the explosion of new imaging options across optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging, including a greatly expanded OCT imaging chapter that features crucial information on OCT-Angiography (OCT-A). Presents new pharmacotherapy data and the latest approaches in anti-VEGF therapy for age-related macular degeneration, diabetic retinopathy, and venous occlusive disease. Features an expanded online video library highlighting the latest surgical techniques and new coverage of complications of vitreoretinal surgery. Contains thorough content updates in every area of retina, including advanced imaging technologies, gene therapy, inflammation and immune responses, white dot syndromes, epigenetic mechanisms, transplantation frontiers to improve retinal function, macular hole, myopic eye disease, ocular trauma, drug delivery to the posterior segment, advances in macular surgery, vitrectomy and complex retinal detachment, tumors, and retinal genetics and biology. Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.

Holland-Frei Cancer Medicine

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Publisher : John Wiley & Sons
ISBN 13 : 111900084X
Total Pages : 2004 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.

Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Metronomic Chemotherapy

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Publisher : Springer
ISBN 13 : 3662436043
Total Pages : 302 pages
Book Rating : 4.6/5 (624 download)

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Book Synopsis Metronomic Chemotherapy by : Guido Bocci

Download or read book Metronomic Chemotherapy written by Guido Bocci and published by Springer. This book was released on 2014-09-04 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies. The clinical pharmacology of metronomic chemotherapy is also considered in depth, encompassing pharmacokinetics, pharmacogenetics, pharmacoeconomics, and adverse drug reactions. The book closes by describing the role of this therapy in the veterinarian clinic.

Antifolate Drugs in Cancer Therapy

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Publisher : Springer Science & Business Media
ISBN 13 : 1592597254
Total Pages : 769 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Antifolate Drugs in Cancer Therapy by : Ann L. Jackman

Download or read book Antifolate Drugs in Cancer Therapy written by Ann L. Jackman and published by Springer Science & Business Media. This book was released on 1999-01-22 with total page 769 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Antifolate Drugs in Cancer Therapy, Ann Jackman and a panel of highly regarded researchers comprehensively review the current status of novel antifolates, an important class of anticancer drugs. The distinguished contributors discuss the preclinical and clinical pharmacology of methotrexate, other dihydrofolate reductase inhibitors, 5-fluorouracil, and the new generation of antifolates-the thymidylate synthase and glycinamide ribonucleotide formyltransferase inhibitors. In addition, they review in depth the modulation of antifolate drugs, folate and antifolate transport mechanisms, polyglutamation, resistance, and drug combinations, as well as pharmacogenomics, pharmacodynamics, regulation of gene expression, and mechanisms of cell death. The wide and progressive scope of Antifolate Drugs in Cancer Therapy provides entré to exciting new avenues for future research, and constitutes a new standard reference for all basic scientists and clinicians engaged in cancer therapeutics.

Rectal Cancer Treatment

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Publisher : Springer Science & Business Media
ISBN 13 : 3540274499
Total Pages : 284 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Rectal Cancer Treatment by : M.W. Büchler

Download or read book Rectal Cancer Treatment written by M.W. Büchler and published by Springer Science & Business Media. This book was released on 2005-10-11 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rectal cancer is one of the most prevalent cancers world-wide. It is also a paradigm for multimodal management, as the combination of surgery, chemotherapy and radiotherapy is often necessary to achieve the optimal outcome. Recently, international experts met in Heidelberg, Germany to discuss the latest developments in the management of rectal cancer, including the anatomic and pathologic basis, staging tools, surgical concepts including fast-track surgery and laparoscopic resection, functional outcome after surgery and the role of radio- and chemotherapy. This monograph summarizes this meeting and gives an extensive overview of the current concepts in management of rectal cancer.

Encyclopedia of Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 3540368477
Total Pages : 3307 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Encyclopedia of Cancer by : Manfred Schwab

Download or read book Encyclopedia of Cancer written by Manfred Schwab and published by Springer Science & Business Media. This book was released on 2008-09-23 with total page 3307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition. With an A-Z format of over 7,000 entries, more than 1,000 contributing authors provide a complete reference to cancer. The merging of different basic and clinical scientific disciplines towards the common goal of fighting cancer makes such a comprehensive reference source all the more timely.

Medicinal Chemistry of Anticancer Drugs

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Publisher : Elsevier
ISBN 13 : 0444626670
Total Pages : 767 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Medicinal Chemistry of Anticancer Drugs by : Carmen Avendaño

Download or read book Medicinal Chemistry of Anticancer Drugs written by Carmen Avendaño and published by Elsevier. This book was released on 2015-06-11 with total page 767 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design. Presents information in a clear and concise way using a large number of figures Historical background provides insights on how the process of drug discovery in the anticancer field has evolved Extensive references to primary literature

Pharmacogenetic Screening of Docetaxel, Irinotecan and Fluoropyrimidines in Cancer Therapy

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Publisher :
ISBN 13 : 9789039341742
Total Pages : 255 pages
Book Rating : 4.3/5 (417 download)

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Book Synopsis Pharmacogenetic Screening of Docetaxel, Irinotecan and Fluoropyrimidines in Cancer Therapy by : Tessa Maria Bosch

Download or read book Pharmacogenetic Screening of Docetaxel, Irinotecan and Fluoropyrimidines in Cancer Therapy written by Tessa Maria Bosch and published by . This book was released on 2006 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Organofluorine Compounds in Biology and Medicine

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Author :
Publisher : Newnes
ISBN 13 : 044453749X
Total Pages : 331 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis Organofluorine Compounds in Biology and Medicine by : V Prakash Reddy

Download or read book Organofluorine Compounds in Biology and Medicine written by V Prakash Reddy and published by Newnes. This book was released on 2015-01-25 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organofluorine Compounds in Biology and Medicine covers topics on biochemically relevant organofluorine compounds and their synthesis and biochemical pathways. Organofluorine compounds have renewed interest in pharmaceutical industry, and therefore a concise book on this topic is highly relevant to the scientific community involved in this area. Covers the synthesis, biochemical, and therapeutic applications of organofluorine compounds Offers a complete text on biochemically relevant organofluorine compounds and their synthesis and mechanistic pathways Provides one of the first major reference books on the biological and medicinal applications of organofluorine chemistry

Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer

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Publisher : Academic Press
ISBN 13 : 0128031204
Total Pages : 506 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer by :

Download or read book Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer written by and published by Academic Press. This book was released on 2015-07-23 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer, the latest volume in the Advances in Pharmacology series, presents not only the function of cytochrome P450 but also its pharmacological roles in inflammation and cancer. Contains contributions from the best authors in the field Ideal reference for those conducting research in cancer, inflammation, cytochrome P450, metabolism, liver disease, and oxidative stress Provides an essential resource for pharmacologists, immunologists, and biochemists