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Fetal Liver Cells A Source Of Specific Immunoglobulin Production In Radiation Chimeras
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Book Synopsis Fetal Liver Cells: a Source of Specific Immunoglobulin Production in Radiation Chimeras by : M. L. Tyan
Download or read book Fetal Liver Cells: a Source of Specific Immunoglobulin Production in Radiation Chimeras written by M. L. Tyan and published by . This book was released on 1967 with total page 17 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adult-thymectomized and intact (C57L x A)F1 mice were X-irradiated (870 rad), and injected ip with 20-33 x 10 to the 6th power nucleated cells from livers of 14-21 day C57B1/6 x C57B1/6 embryos. In other experiments the mice received 300,000 syngeneic bone marrow cells (iv), and dissociated gut cells from 14-21 day C57B1/6 x C57B1/6 embryos (ip). The sera from these chimeras were assayed for the presence of donor-type gamma-globulins. These mice were also sensitized to a synthetic polypeptide (TGAL), and their sera tested for total and for donor-type anti-TGAL antibody. All the mice, thymectomized as well as intact, which received fetal liver cells, had significant quantities of donor-type gamma-globulins in their sera by 58 days postirradiation. Only 1 of 14 mice injected with embryonic gut cells was found to have donor-type gamma-globulins by 95 days postirradiation. Following immunization with TGAL, the fetal liver cell chimeras (intact thymus) exhibited specific antibody (10/10), while none of the thymectomized chimeras (0/21) were positive for this antibody. In the immunized, intact-thymus group, significant amounts of the specific anti-TGAL antibody was of donor origin. Thus, mouse fetal liver, as early as the 14th day of gestation, contains lymphoid stem cells capable of immunoglobulin synthesis in the absence of thymus. However, their ability to form certain specific antibodies is dependent upon intact thymic function. The results suggest that the donor-type immunoglobulins synthesized in the absence of the thymus may be 'nonsense' of 'defective' antibody-like molecules. (Author).
Download or read book Nuclear Science Abstracts written by and published by . This book was released on 1975 with total page 1550 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Fetal liver transplantation by : J.-L. Touraine
Download or read book Fetal liver transplantation written by J.-L. Touraine and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Technical Abstract Bulletin by : Defense Documentation Center (U.S.)
Download or read book Technical Abstract Bulletin written by Defense Documentation Center (U.S.) and published by . This book was released on 1967 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Government-wide Index to Federal Research & Development Reports by :
Download or read book Government-wide Index to Federal Research & Development Reports written by and published by . This book was released on 1967-04 with total page 1078 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Research Grants Index by : National Institutes of Health (U.S.). Division of Research Grants
Download or read book Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and published by . This book was released on 1968 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Haemopoietic Cells by : Donald Metcalf
Download or read book Haemopoietic Cells written by Donald Metcalf and published by . This book was released on 1971 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1994 with total page 1364 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Proceedings of the International Congress of the Transplantation Society by : Transplantation Society
Download or read book Proceedings of the International Congress of the Transplantation Society written by Transplantation Society and published by . This book was released on 1967 with total page 798 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Fetal Liver Transplantation by : Robert Peter Gale
Download or read book Fetal Liver Transplantation written by Robert Peter Gale and published by . This book was released on 1985 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Government Reports Announcements by :
Download or read book Government Reports Announcements written by and published by . This book was released on 1967-05 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Journal of the National Cancer Institute by :
Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 1977 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Information Transfer in the Immune System by : Thomas G. Wegmann
Download or read book Information Transfer in the Immune System written by Thomas G. Wegmann and published by . This book was released on 1969 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Bibliography of Scientific and Industrial Reports by :
Download or read book Bibliography of Scientific and Industrial Reports written by and published by . This book was released on 1967 with total page 1212 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis U.S. Government Research & Development Reports by :
Download or read book U.S. Government Research & Development Reports written by and published by . This book was released on 1967 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Government Reports Announcements & Index by :
Download or read book Government Reports Announcements & Index written by and published by . This book was released on 1967 with total page 1212 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Journal by : National Cancer Institute (U.S.)
Download or read book Journal written by National Cancer Institute (U.S.) and published by . This book was released on 1964-04 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt:
