Fast Facts Immuno Oncology

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Fast Facts: Immuno-Oncology

Author : Stephen Clarke
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318068217
Total Pages : 128 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Immuno-Oncology by : Stephen Clarke

Download or read book Fast Facts: Immuno-Oncology written by Stephen Clarke and published by Karger Medical and Scientific Publishers. This book was released on 2021-07-07 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: The treatment of cancer has been revolutionized by therapies that modulate the immune system, with benefits for quality of life and survival. Standards of care have changed to reflect developments, but the area is moving fast. Keeping abreast of new therapies and trial data can be challenging. This second edition of 'Fast Facts: Immuno-Oncology' takes you from the fundamentals of immunology through to the new concepts of immunoediting and immunotherapy and likely future directions. Whether you have worked in oncology for decades and need a refresher or you are just starting out and need a crash course, this book provides all you need to know about immuno-oncology, concisely summarized. Table of Contents: • Components of the immune system • How cancers evade the immune system • How cancer immunotherapy works • Clinical use of immune checkpoint inhibitors • The future of immuno-oncology

Fast Facts: Hypertension

Author : Graham A. MacGregor
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 1910797030
Total Pages : 98 pages
Book Rating : 4.9/5 (17 download)

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Book Synopsis Fast Facts: Hypertension by : Graham A. MacGregor

Download or read book Fast Facts: Hypertension written by Graham A. MacGregor and published by Karger Medical and Scientific Publishers. This book was released on 2016-02-15 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypertension is the biggest cause of death and disability in the world, yet it remains underdiagnosed, undertreated and, in many cases, poorly controlled. As in the previous edition, 'Fast Facts: Hypertension' advises on: • accurate measurement of blood pressure and problems such as 'white-coat' hypertension • routine assessments for people with high blood pressure • other modifiable risk factors (smoking, high cholesterol levels etc.) • non-pharmacological measures (reducing salt, losing weight, increasing physical activity etc.) • rational and effective use of all drug treatments • identification of people with secondary hypertension • treatment of children, pregnant women, the elderly and patients with diabetes. Updates in this new edition include: • distinguishing between patients with primary (low renin) and secondary aldosteronism • greater use of home BP measurement in clinical decision-making • the latest thinking on BP treatment thresholds • new guidance on fourth-line therapy for resistant hypertension Sometimes dubbed 'the silent killer', hypertension rarely produces symptoms until it manifests as a heart attack or stroke, so early identification of the condition and appropriate management are vital. This practical readable refresher for every-day use supports better investigation and treatment of high blood pressure by primary care providers and better self-management by patients. Contents: • The dangers of raised blood pressure • Causes • Investigation • When to treat • How to treat • Special patient groups • Uncontrolled hypertension • Useful resources

Fast Facts: Peripheral T-cell Lymphoma

Author : F. Foss
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 1912776197
Total Pages : 101 pages
Book Rating : 4.9/5 (127 download)

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Book Synopsis Fast Facts: Peripheral T-cell Lymphoma by : F. Foss

Download or read book Fast Facts: Peripheral T-cell Lymphoma written by F. Foss and published by Karger Medical and Scientific Publishers. This book was released on 2019-06-20 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt: The peripheral T-cell lymphomas (PTCLs) are a heterogenous group of rare entities. Whilst cytogenetic and molecular identifiers are being identified, accurate diagnosis remains challenging, requiring careful, expert integration of the clinical and pathological findings. The treatment of PTCL is also challenging. Protocols for the different subtypes are only just beginning to emerge, hindered by the complexities of conducting trials in such uncommon and varied conditions. While first-line treatment with conventional chemotherapy is seldom curative, patients who achieve remission may be eligible for stem cell transplantation, offering the possibility of long-term disease control if not cure. Targeted biologics are also being developed as unique cytotoxic markers are identified. 'Fast Facts: Peripheral T-Cell Lymphomas' is a new title in the Fast Facts extensive hemato-oncology library, written by experts in this emerging field. This handbook will be useful to anyone involved in the care of patients with PTCL, including haematologists, oncologists, specialist nurses and primary care providers, raising awareness of these rare lymphomas and the current – and emerging – approaches to diagnosis and treatment.

Fast Facts: Managing Immune-Related Adverse Events in Oncology

Author : Helen Westman
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318072478
Total Pages : 142 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Managing Immune-Related Adverse Events in Oncology by : Helen Westman

Download or read book Fast Facts: Managing Immune-Related Adverse Events in Oncology written by Helen Westman and published by Karger Medical and Scientific Publishers. This book was released on 2023-04-30 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fast Facts: Managing Immune-Related Adverse Events in Oncology, 2nd edition, provides an overview of immuno-oncology and an update on immune checkpoint inhibitors and their associated toxicities, alongside the principles of diagnosing and managing immune-related adverse events, important nursing care considerations and a set of convenient management summaries for quick reference. As such, it is essential reading for all members of the cancer care team. Table of Contents: • Immunotherapy and its side effects: an overview • Gastrointestinal and hepatic adverse events • Dermatologic adverse events • Endocrine-related adverse events • Pulmonary adverse events • Less frequent adverse events • Optimizing patient care and early recognition of irAEs • Management summaries

Fast Facts: Glioblastoma

Author : Mairéad McNamara
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 1912776707
Total Pages : 76 pages
Book Rating : 4.9/5 (127 download)

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Book Synopsis Fast Facts: Glioblastoma by : Mairéad McNamara

Download or read book Fast Facts: Glioblastoma written by Mairéad McNamara and published by Karger Medical and Scientific Publishers. This book was released on 2020-02-26 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glioblastoma (also known as glioblastoma multiforme) is a malignant intrinsic tumor thought to arise from populations of stem/progenitor cells in the brain. It is the most common aggressive intrinsic brain tumor in adults, with the potential to spread rapidly within the brain. Patients with glioblastoma face a poor prognosis, with median overall survival of approximately 15 months. However, our growing understanding of the molecular biology of gliomas means that this outlook may be improving. The identification of clinically relevant subgroups defined by specific genetic mutations is challenging the traditional delineation between low- and high-grade gliomas that has been based on histological appearance and imaging. Indeed, it is becoming clear that, as a molecular entity, a glioblastoma, which by traditional classification is a grade IV glioma, may present with a lower grade initially and then become more aggressive – an important addition to the established concept. The care of a patient with a glioblastoma requires a coordinated approach delivered by a multidisciplinary team, with the aim of maintaining quality of life for as long as possible. Here, we provide a concise overview of the diagnosis and management of glioblastoma, as well as discussion of our emerging understanding of the molecular drivers that are helping us to delineate different patient subgroups. These subgroups will, hopefully, allow more targeted treatments in the future. This resource will be of interest to all those involved in caring for patients with this aggressive brain tumor, including neurologists, neurosurgeons, neuro-oncologists, radiation oncologists, palliative care specialists, specialist nurses and medical students. Contents: • Epidemiology, pathophysiology and classification • Clinical presentation • Diagnosis • Management • Treatment of associated conditions • Emerging research and treatment

Fast Facts: Cholangiocarcinoma

Author : R.T. Shroff
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318068101
Total Pages : 84 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Cholangiocarcinoma by : R.T. Shroff

Download or read book Fast Facts: Cholangiocarcinoma written by R.T. Shroff and published by Karger Medical and Scientific Publishers. This book was released on 2021-04-08 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cholangiocarcinomas (CCAs) are a group of heterogeneous tumors that have traditionally had poor prognosis. Despite being rare, the global incidence of CCA has increased dramatically over the last few decades. However, alongside this, there have been advancements in our understanding, diagnosis and treatment, improving the overall survival and quality of life of patients with advanced disease. This compact yet comprehensive review of CCA serves as a guide for physicians, oncologists, allied health professionals, scientists, patients and caregivers to update their knowledge of the most recent clinical developments and most promising areas of research. Table of Contents: • Pathophysiology, etiology and epidemiology • Diagnosis • Biliary drainage and supportive care • Surgical resection and transplantation • Translational research • Systemic therapy • Immunotherapy • Radiotherapy and photodynamic therapy

SITC’s Guide to Managing Immunotherapy Toxicity

Author : Marc S. Ernstoff, MD
Publisher : Springer Publishing Company
ISBN 13 : 0826172156
Total Pages : 275 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis SITC’s Guide to Managing Immunotherapy Toxicity by : Marc S. Ernstoff, MD

Download or read book SITC’s Guide to Managing Immunotherapy Toxicity written by Marc S. Ernstoff, MD and published by Springer Publishing Company. This book was released on 2019-03-15 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Society for Immunotherapy of Cancer's handbook,SITC’s Guide to Managing Immunotherapy Toxicity, is a practical reference to managing side effects associated with FDA-approved cancer immunotherapy drugs. Separated into two parts, Part I contains chapter-based overviews of immune checkpoint inhibitors in the clinic, starting with anti-CTLA4 agents, anti-PD1/PD-L1 agents, and approved immunotherapeutic combinations. These chapters cover relevant mechanisms of action, indications, and toxicities seen while combating early, advanced, and metastatic stages in cancer patients. Part II is structured by common and uncommon toxicities that affect major organ sites throughout the body. It begins with a general summary of principles and management options followed by chapters focusing on specific toxicities such as rash and mucosal irritation, muscle and joint toxicity, diarrhea and colitis, pneumonitis, endocrine toxicities, neurological toxicities, cardiac toxicity, renal toxicity, hematologic toxicity, and ocular toxicities. Each chapter provides guidance on how to assess and treat the toxicity and how to support the patient through acute and chronic effects with detailed summary tables for quick reference. Part II concludes with chapters covering management of special patient populations, including patients with autoimmune disease and geriatric patients, treatment and management of fatigue, and a final chapter dedicated to cost effectiveness and the toll of financial toxicity on patients and caregivers. With chapters written by world-recognized leaders in the immuno-oncology field, this text provides thorough coverage of the toxicity and management of adverse effects for immune checkpoint inhibitors. It is an indispensable resource for clinical oncologists, emergency physicians, hospitalists and other medical practitioners in both the hospital and community clinic settings, especially as the use of immune checkpoint inhibitors becomes a fixture in oncology care. Key Features: Outlines strategies for treating high-risk patients facing an acute or chronic side effect to immunotherapy Provides numerous tables that condense and highlight pertinent information for quick reference Describes the various clinical presentations and toxic reactions caused by immunotherapy Purchase includes access to the eBook for use on most mobile devices or computer

Fast Facts: Prostate Cancer

Author : Roger S. Kirby
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 1910797375
Total Pages : 138 pages
Book Rating : 4.9/5 (17 download)

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Book Synopsis Fast Facts: Prostate Cancer by : Roger S. Kirby

Download or read book Fast Facts: Prostate Cancer written by Roger S. Kirby and published by Karger Medical and Scientific Publishers. This book was released on 2017-03-08 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prostate cancer is unusual among solid tumors in that the majority of affected men die with, rather than of, the disease. This presents many challenges to healthcare professionals and patients in terms of deciding if, when and how to intervene in order to control tumor growth and spread, thereby extending survival but without compromising quality of life. This is the ninth edition of 'Fast Facts: Prostate Cancer' since 1996, testament to the rapid changes in the field and the steadily improving outlook for patients. This new edition provides many key updates: • the Gleason grade grouping, which has valuable prognostic value • nomograms to evaluate risk • our rapidly expanding understanding of the genetics and underlying pathogenesis of prostate cancer and the development of genomic tests to help identify those at greatest risk of developing clinically significant disease • the continuing debate about the role of PSA in the screening, detection and monitoring of prostate cancer • advances in imaging techniques, particularly multiparametric MRI, which is improving the accuracy of biopsy and reducing the numbers of negative biopsies • the roles of drugs, surgery and radiotherapy in the treatment of prostate cancer at different stages, and our ever-improving understanding of when and how best to intervene, aided by improving understanding of the risk factors for disease progression. Primarily intended for primary care providers, specialist nurses, junior doctors and allied healthcare professionals, this highly readable resource provides a comprehensive overview of prostate cancer, enabling fully informed discussions with patients about this complex disease. Contents: • Epidemiology and pathophysiology • Diet, lifestyle and chemoprevention • Screening and early detection • Diagnosis, staging and prognostic indicators • Management of clinically localized disease • Managing recurrence after initial therapy • Management of metastatic prostate cancer • Management of castrate-resistant prostate cancer • Survivorship and treatment complications

Fast Facts: Bladder Cancer

Author : Seth P. Lerner
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 1910797642
Total Pages : 98 pages
Book Rating : 4.9/5 (17 download)

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Book Synopsis Fast Facts: Bladder Cancer by : Seth P. Lerner

Download or read book Fast Facts: Bladder Cancer written by Seth P. Lerner and published by Karger Medical and Scientific Publishers. This book was released on 2018-02-05 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of the biology of bladder cancer has advanced remarkably since the second edition of 'Fast Facts: Bladder Cancer' was published in 2006. Five new immunotherapies targeting the PD-1 axis were approved in 2016 and 2017 for the treatment of advanced bladder cancer, reflecting this transformative explosion in knowledge about the biology of the disease. This new era of targeted treatment offers hope to patients, particularly those with advanced disease. However, for clinicians it means a lot to understand in terms of how these immunotherapies are integrated into the treatment paradigm. Who they are suitable for? When are they best used? What is the optimal sequence of treatments for individual patients? This third edition of 'Fast Facts: Bladder Cancer' has been updated extensively throughout by two new authors, bringing a fresh perspective. Key updates include: • the latest understanding of pathology and biology • current standards for investigation, imaging and diagnosis • the critical role that awareness of the significance of hematuria among patients and primary care health professionals can make to earlier detection at curable stages of the disease • the roles of drugs, surgery and radiation therapy in treatment at different stages of bladder cancer, and when and how best to intervene, aided by understanding of the risk factors for disease relapse and progression • a new chapter about immunotherapy for bladder cancer • future trends in a rapidly evolving field. 'Fast Facts: Bladder Cancer' is a concise guide that will be of value to clinicians and health professionals involved in the detection and treatment of bladder cancer. This highly readable resource provides a comprehensive and current view of this complex disease, enabling informed discussions with patients. Contents: • Epidemiology and etiology • Pathology and biology • Clinical presentation • Investigations • Management of non-muscle-invasive disease • Management of muscle-invasive disease • Management of advanced and metastatic disease • Immunotherapy • Future trends • Useful resources

The Basics of Cancer Immunotherapy

Author : Haidong Dong
Publisher : Springer
ISBN 13 : 3319706225
Total Pages : 164 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis The Basics of Cancer Immunotherapy by : Haidong Dong

Download or read book The Basics of Cancer Immunotherapy written by Haidong Dong and published by Springer. This book was released on 2018-01-05 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides patients and their physicians (especially “non-oncologist” health care providers) with a clear and concise introduction to cancer immunotherapy, which, unlike traditional forms of cancer therapy, acts by boosting the patient’s own immune system to fight cancer. The unique features of cancer immunotherapy make its management, monitoring and side-effects different from those of traditional cancer therapy. Especially novel are the side effects of cancer immunotherapy, necessitating greater awareness for both patients and physicians in order to minimize complications of therapy. The patient-friendly, concise, easy-to-understand, and up-to-date knowledge presented in this book will inform patients about the benefits and risks of cancer immunotherapy, and help them and their care providers to understand how immunotherapy would control their unique disease. Researchers and academic professionals in the field of cancer immunotherapy will also find clear and useful information to help them communicate with patients or address unresolved problems. Some key features of the book are: Expertise. All editors and authors are scientists and oncologists specializing in cancer immunotherapy, and are involved in scientific discovery from the early stage of immune-checkpoint inhibitors to today’s daily patient care. Their insights, expertise and experience guarantee the high quality and authority in the science, medicine and practice of cancer immunotherapy. Patient-friendly. This book is written for cancer patients in order to meet their needs when considering immunotherapy. As an educational tool, this book will help the reader balance the risks and benefits based on both science and clinical facts, and therefore to make the best choice in receiving or withdrawing from immunotherapy. Disease Specificity. Cancer is a complicated disease involving multiple stages and pathology. Its response to immunotherapy is individualized and varies depending on cancer types. The authors’ expertise in treating different types of cancers, including melanoma, lung, kidney, bladder, and lymphoma, provides disease-specific insights in applying immunotherapy to each disease.

Fast Facts for Nurse Practitioners

Author : Nadine M. Aktan, PhD, APN-BC
Publisher : Springer Publishing Company
ISBN 13 : 0826148735
Total Pages : 228 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Fast Facts for Nurse Practitioners by : Nadine M. Aktan, PhD, APN-BC

Download or read book Fast Facts for Nurse Practitioners written by Nadine M. Aktan, PhD, APN-BC and published by Springer Publishing Company. This book was released on 2020-07-14 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to provide an insider view of the latest advances and trends in the full range of clinical subspecialty areas. Fast Facts for Nurse Practitioners: Practice Essentials for Clinical Subspecialties takes the busy advanced practice provider or student on a journey through the clinical subspecialties. The author, a highly experienced nurse practitioner, has immersed herself in each of these clinical areas and interviewed medical specialists to identify the latest advances, trends, and tips to more confidently and competently assess, diagnose, manage, and refer patients across the lifespan. The book addresses hot topics in allergy and immunology, cardiology, dermatology, endocrinology, gastroenterology, hematology and oncology, infectious disease, nephrology, neurology, obstetrics and gynecology, ophthalmology, orthopedics, otolaryngology, pediatrics, psychiatry, pulmonology, rheumatology, and urology. Each chapter provides information on common chief complaints, pathophysiology, diagnostic considerations, and key points for management or referral. This concise reference provides evidence-based strategies for managing ever-changing patient needs in an easy-to-digest format. Key Features: Serves the needs of advanced practice providers and students Offers the latest advances and trends for all clinical subspecialty areas in one concise, quick-reference resource Provides evidence-based guidelines to support the principles of assessment, differential diagnosis, management, and referral Highlights only the most relevant and timely information, allowing readers to save time, stay current, and improve patient outcomes

Pocket Oncology

Author : Alexander Drilon
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451187629
Total Pages : 352 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis Pocket Oncology by : Alexander Drilon

Download or read book Pocket Oncology written by Alexander Drilon and published by Lippincott Williams & Wilkins. This book was released on 2014 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pocket Oncology, developed and edited by oncologists at Memorial Sloan-Kettering Cancer Center, is a simple, yet comprehensive, review of basic principles of cancer management. Prepared in the style and format of books in the popular Pocket Notebook series, Pocket Oncology is intended as a quick reference presented in easy to read bulleted text, and using diagrams and charts where appropriate. Each oncologic disease is presented on two facing pages that review initial clinical presentation, pathophysiology, staging, current standard of care treatments, and active areas of current research. Edited by Alexander Drilon and Michael Postow, the content of the book has been written by medical oncology fellows and each disease entity has been authoritatively reviewed by an oncologist with specific expertise in each subspecialty of oncology. Features: -simple, comprehensive, review of basic principles of oncology in easy to read bulleted text, using diagrams and charts where appropriate. -its small size makes it easy to carry the pocket of a lab coat for quick reference to information while in the hospital or oncology clinic. -perfect for medical students, residents, fellows, physician assistants, and nurses who perform daily oncologic care.

Fast Facts: Manejo de eventos adversos relacionados con el sistema inmunitario en oncología

Author : B.L. Rapoport
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318066362
Total Pages : 120 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Manejo de eventos adversos relacionados con el sistema inmunitario en oncología by : B.L. Rapoport

Download or read book Fast Facts: Manejo de eventos adversos relacionados con el sistema inmunitario en oncología written by B.L. Rapoport and published by Karger Medical and Scientific Publishers. This book was released on 2020-02-29 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: El uso de inmunoterapia para el tratamiento de neoplasias tanto sólidas como hematológicas es extenso. Los inhibidores del punto de control inmunitario en particular han demostrado ser promisorios en el tratamiento del melanoma, cáncer pulmonar no microcítico y otros tipos de cáncer. La mayor parte de los eventos adversos relacionados con el sistema inmunitario asociados con estos fármacos son leves a moderados, pero en ocasiones también se informan eventos adversos graves que ocasionalmente ponen en riesgo la vida. El manejo eficaz de los eventos adversos relacionados con el sistema inmunitario requiere un reconocimiento temprano, así como de la intervención pronta con esteroides, inmunosupresión y/o estrategias inmunomoduladoras apropiadas para el órgano afectado y la gravedad de la toxicidad. También es esencial educar a los pacientes sobre el potencial y el reconocimiento de estos eventos adversos. Con las inmunoterapias volviéndose cada vez más frecuentes y los profesionales de la salud familiarizándose más con los beneficios de combinar estrategias de inmunoterapia, surge una necesidad apremiante de contar con una guía para reconocer y manejar los eventos adversos relacionados con el sistema inmunitario que puedan surgir. Este recurso proporciona una revisión general de inmunooncología y una actualización sobre los inhibidores del punto de control inmunitario y sus toxicidades relacionadas, junto con los principios de diagnóstico y manejo de los eventos adversos relacionados con el sistema inmunitario, consideraciones importantes sobre el cuidado de enfermería y una serie de resúmenes de manejo convenientes para referencia rápida. Como tal, es una lectura esencial para todos los miembros del equipo de atención oncológica. Indice: • Inmunoterapia y sus efectos secundarios: una revisión general • Eventos adversos gastrointestinales y hepáticos • Eventos adversos dermatológicos • Eventos adversos relacionados con el sistema endocrino • Eventos adversos pulmonares • Eventos adversos menos frecuentes • Optimización de la atención al paciente y reconocimiento temprano de eventos adversos relacionados con el sistema inmunitario • Resúmenes de manejo

Molecular Biology of the Cell

Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fast Facts: Comprehensive Genomic Profiling

Author : Bernardo L. Rapoport
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318068187
Total Pages : 109 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Fast Facts: Comprehensive Genomic Profiling by : Bernardo L. Rapoport

Download or read book Fast Facts: Comprehensive Genomic Profiling written by Bernardo L. Rapoport and published by Karger Medical and Scientific Publishers. This book was released on 2020-10-20 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. 'Fast Facts: Comprehensive Genomic Profiling' provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge – or memory – of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject. Contents: • Genetic mutations and biomarkers • Understanding next-generation sequencing • Elements of comprehensive genomic profiles • Role in precision oncology • Predictive and prognostic biomarkers • Overcoming barriers to genotype-directed therapy

Abcs Of Cancer, The: Separating The Facts From The Myths

Author : Meshach Asare-werehene
Publisher : World Scientific
ISBN 13 : 9811212279
Total Pages : 200 pages
Book Rating : 4.8/5 (112 download)

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Book Synopsis Abcs Of Cancer, The: Separating The Facts From The Myths by : Meshach Asare-werehene

Download or read book Abcs Of Cancer, The: Separating The Facts From The Myths written by Meshach Asare-werehene and published by World Scientific. This book was released on 2020-06-16 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This exciting reader-friendly book addresses the general perspectives of cancer in diverse ways — everyday lifestyle, nutrition, environmental factors as well as genetics. The author, an expert in Immuno-Oncology, makes conscious efforts to break down the complexities of cancer development through the use of scientific evidences and everyday activities. There are so many myths about cancer out there. This book employs scientific basis to separate the facts from the myths while making it comprehensible to all readers irrespective of their scientific background. Readers are also introduced to the modern trends in cancer therapeutics.

The Immortal Life of Henrietta Lacks

Author : Rebecca Skloot
Publisher : Crown
ISBN 13 : 0307589382
Total Pages : 386 pages
Book Rating : 4.3/5 (75 download)

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Book Synopsis The Immortal Life of Henrietta Lacks by : Rebecca Skloot

Download or read book The Immortal Life of Henrietta Lacks written by Rebecca Skloot and published by Crown. This book was released on 2010-02-02 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: #1 NEW YORK TIMES BESTSELLER • “The story of modern medicine and bioethics—and, indeed, race relations—is refracted beautifully, and movingly.”—Entertainment Weekly NOW A MAJOR MOTION PICTURE FROM HBO® STARRING OPRAH WINFREY AND ROSE BYRNE • ONE OF THE “MOST INFLUENTIAL” (CNN), “DEFINING” (LITHUB), AND “BEST” (THE PHILADELPHIA INQUIRER) BOOKS OF THE DECADE • ONE OF ESSENCE’S 50 MOST IMPACTFUL BLACK BOOKS OF THE PAST 50 YEARS • WINNER OF THE CHICAGO TRIBUNE HEARTLAND PRIZE FOR NONFICTION NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The New York Times Book Review • Entertainment Weekly • O: The Oprah Magazine • NPR • Financial Times • New York • Independent (U.K.) • Times (U.K.) • Publishers Weekly • Library Journal • Kirkus Reviews • Booklist • Globe and Mail Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than sixty years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave. Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of. Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah. Deborah was consumed with questions: Had scientists cloned her mother? Had they killed her to harvest her cells? And if her mother was so important to medicine, why couldn’t her children afford health insurance? Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.