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F And G Black Mambas
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Book Synopsis F and G Black Mambas by : Nancy White
Download or read book F and G Black Mambas written by Nancy White and published by . This book was released on 2009-01-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The black mamba is one of the most dangerous snakes in the world. It is big, fast, and very aggressive when threatened. It is also highly poisonous: a black mamba's potent venom can kill a person within 20 minutes. A single bite has enough venom to kill 20-40 grown men! Needless to say, without treatment a black mamba bite is 100% fatal. Packed with fascinating facts and large, colorful photos, Black Mambas: Sudden Death! introduces emergent readers to the natural habitat, physical characteristics, diet, and behavior of this deadly serpent.
Book Synopsis Handbook of Novel Psychoactive Substances by : Ornella Corazza
Download or read book Handbook of Novel Psychoactive Substances written by Ornella Corazza and published by Routledge. This book was released on 2018-10-10 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Novel Psychoactive Substances (NPS) provides a comprehensive overview of the challenges that clinicians face when dealing with NPS and discusses how the profile of patients and their socio-demographic characteristics frame the serious public health concern that NPS pose. It presents various clinical cases, as well as detailed accounts of symptoms, psychopathology, toxicity, and overall clinical management that NPS require. This handbook brings together a unique collection of chapters written by leading experts in the field, who have felt the need to share their knowledge and experience to improve the clinical practice on NPS and the wellbeing of their patients.
Book Synopsis Strike of the Black Mamba by : Ian Krüger
Download or read book Strike of the Black Mamba written by Ian Krüger and published by Ian Kruger. This book was released on 2008-02-14 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: The unthinkable has happened. An environmental organization warned the world against it. Still, nobody believed that it would turn out like this. But Donald Morse proves everyone wrong. Defying all security measures, he manages to steal a shipment of nuclear material from a cargo ship destined for Japan's nuclear power reactors. Could anything be worse than this scenario? Perhaps the fact that Donald Morse knows that South African scientists developed extremely dangerous nuclear weapons during the apartheid years, weapons that the world thought were not possible to construct. Donald has information where these deadly weapons are hidden - and he has plans to get them out. Ken Palmer is sent by the FBI to find Donald Morse and to arrest him. But Ken has to deal with traitors from within as well as onslaughts on his life. However, he discovers the real spine-chilling reason for Donald's need for the nuclear weapons and he realizes that Donald has to be stopped in any way possible.
Book Synopsis Novel Psychoactive Substances by : Ornella Corazza
Download or read book Novel Psychoactive Substances written by Ornella Corazza and published by Springer. This book was released on 2017-08-09 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: In light of the recent emergence of Novel Psychoactive Substances (NPS) on a global scale, this book provides a timely analysis of the social and economic impact of the NPS phenomenon, and of the global policy and regulatory responses to it. It presents the first comprehensive overview of the international regulation, policy and market structure of the NPS phenomenon, offering a guide to inform legislative discussions and demonstrating from a comparative perspective the different approaches used to address the rise of NPS to date. It covers topics such as organized crime, drug markets, clinical evidence on NPS, and different regulatory approaches also in less explored settings such as prisons and sport environments. Overall, this highly informative and well-structured repository of different experiences with NPS policy, law and regulation offers an essential primary source of evidence for anyone interested in the area of drug and NPS policy, health economics and p ublic health.
Book Synopsis Recent Changes in Drug Abuse Scenario The Novel Psychoactive Substances (NPS) Phenomenon by : Fabrizio Schifano
Download or read book Recent Changes in Drug Abuse Scenario The Novel Psychoactive Substances (NPS) Phenomenon written by Fabrizio Schifano and published by MDPI. This book was released on 2019-01-15 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Recent Changes in Drug Abuse Scenario: The Novel Psychoactive Substances (NPS) Phenomenon" that was published in Brain Sciences
Download or read book Lord Dunsany written by S. T. Joshi and published by Rowman & Littlefield. This book was released on 2013-12-13 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anglo-Irish writer Lord Dunsany (1878–1957) was a pioneering writer in the genre of fantasy literature and the author of such celebrated works as The Book of Wonder (1912) and The King of Elfland’s Daughter (1924). Over the course of a career that spanned more than five decades, Dunsany wrote thousands of stories, plays, novels, essays, poems, and reviews, and his work was translated into more than a dozen languages. Today, Dunsany’s work is experiencing a renaissance, as many of his earlier works have been reprinted and much attention has been paid to his place in the history of fantasy and supernatural literature. This bibliography is a revision of the landmark volume published in 1993, which first charted the full scope of Dunsany’s writing. This new edition not only brings the bibliography up to date, listing the dozens of new editions of Dunsany’s work that have appeared in the last two decades and the wealth of criticism that has been written about him, but also records many obscure publications in Dunsany’s lifetime that have not been previously known or identified. In all, the bibliography has been expanded by at least thirty percent. Among this new material are dozens of uncollected short stories, newspaper articles, and poems, and many books, essays, and reviews of Dunsany’s work published over the past century. Altogether, this bibliography is the definitive listing of works by and about Dunsany and will be the foundation of Dunsany studies for many years to come.
Download or read book Black Mamba written by Ancilla2015 and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis An insight into the metabolism of New Psychoactive Substances by : Jakob Wallgren
Download or read book An insight into the metabolism of New Psychoactive Substances written by Jakob Wallgren and published by Linköping University Electronic Press. This book was released on 2020-09-09 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Psychoactive Substances (NPS) is an umbrella term covering hundreds of substances across different drug groups. Many of these substances were originally developed for therapeutic use but have later appeared on the recreational drug market. The use of NPS has been associated with many outbreaks leading to hospitalizations and has been implicated in numerous fatalities worldwide. To be able to analytically detect drugs in a forensic setting is vital in the fight against the abuse of NPS. One of the most notable challenges in detection of NPS is the identification of major urinary metabolites for use as biomarkers. Furthermore, given the lack of reference standards in most metabolism studies, the major urinary metabolites can often only be tentatively determined. This thesis describes the synthesis and analysis of potential metabolites used to identify the exact structures of major metabolites of the synthetic cannabinoid AKB-48, fentanyl and five fentanyl analogues in authentic human urine samples and/or hepatocyte incubations. Synthetic targets were chosen based on previous metabolism studies by our research group. Subsequently, synthetic routes were developed to produce numerous potential metabolites across the studied NPS. The synthesized reference standards were analyzed by LC-QTOF-MS alongside hepatocyte drug incubations and authentic human urine samples. Comparison of the resulting analytical data was used to determine the exact structures of many metabolites. This includes urinary metabolites of AKB-48 with a single hydroxyl group situated on a secondary carbon of the adamantane moiety, or position 3 or 5 of the pentyl side chain. For the studied fentanyls, the ?-OH and the 4’-OH metabolites were abundant metabolites identified in hepatocyte incubations while the 4’-OH, 4’-OH-3’-OMe and 3’,4’-diOH were the favored metabolic motifs among the metabolites identified in urine. Additionally, a concise synthetic route to produce synthetic cannabinoid metabolites with the 4-OH-5F pentyl side chain motif was developed and demonstrated for four synthetic cannabinoids. These findings and the developed synthetic routes can be used to provide forensic toxicology laboratories with urinary biomarkers for drug detection. Moreover, the synthesized reference standards of major metabolites can be studied to better understand the toxicity of their parent drugs. Nya psykoaktiva substanser (NPS) är det officiella namnet för den grupp droger som tidigare har kallats för designerdroger, nätdroger eller internetdroger. NPS definieras som droger som utgör ett likvärdigt hot mot folkhälsan som droger som återfinns på Förenta Nationernas narkotikakonventioner men som själva inte återfinns under dessa konventioner. Det finns hundratals olika rapporterade NPS spridda över olika droggrupper, såsom syntetiska cannabinoider och syntetiska opioider. Vissa av dessa droger syntetiserades ursprungligen i forskningssyfte, men tog sig senare in på den illegala drogmarknaden. De mer nyligen framtagna NPS är ofta designade att efterlikna effekterna av etablerade droger, såsom morfin eller ?9-THC, vilket är den huvudsakliga psykoaktiva substansen i cannabis. Användandet av NPS har associerats till många kluster av intoxikationer som har lett till hospitaliseringar. Många har även dött till följd av användandet av NPS. Inte minst i USA där en grupp av NPS kallad för fentanylanaloger är högst delaktig i den pågående opioidkrisen. Den ständiga inströmningen av nya NPS leder till att detektion av och diskriminering mellan dem utgör en svår utmaning för forensiska toxikologilaboratorier. Tillgången av lämpliga referenssubstanser möter inte deras efterfrågan, delvis på grund av att vilka biomarkörer som är optimala för drogdetektion inte alltid är uppenbart. Till exempel så är metabolismen av syntetiska cannabinoider i regel både snabb och omfattande. Av den anledningen kan användandet av modersubstansen som biomarkör vid analys av urin leda till falskt negativa resultat. Urin som biologisk matris har många fördelar jämfört med blod. Till exempel så har urin ett längre detektionsfönster och högre drogkoncentrationer. För att kunna identifiera optimala biomarkörer för droganalys av urinprover så måste drogernas metabolism utredas. De flesta metabolismstudier använder sig av humana levermikrosomer eller hepatocyter som inkuberas tillsammans med droger för att generera metaboliter in vitro. Urinprover från individer i vilkas blod det har återfunnits droger används också men tillgången är tyvärr begränsad. Dessa metaboliter separeras sedan med hjälp av kromatografiska tekniker och deras kemiska strukturer bestäms med hjälp av masspektrometri. Dock så är utvärderingen av masspektrometridata komplicerad och det är heller inte möjligt att skilja på vissa positionsisomerer genom att enbart analysera masspektrometridata. För att kunna möjliggöra exakt strukturutredning så krävs referensstandarder. Därför var målet med denna avhandling att addera syntes och analys av referensstandarder till de etablerade tillvägagångssätten att studera metabolismen av NPS. Ett stort antal potentiella metaboliter av AKB-48 och andra syntetiska cannabinoider samt av fentanyl och fentanylanaloger syntetiserades. Genom att använda dessa referensstandarder i metabolismstudier så kunde de exakta kemiska strukturerna för många metaboliter bestämmas. Dessutom så identifierades mönster i de metaboliska profilerna bland fentanyl och fentanylanaloger. Dessa mönster kan användas för att förbättra predikteringen av metaboliter för andra nuvarande och kommande fentanylanaloger. Dessa resultat samt de utvecklade syntesvägarna kan nyttjas i framställningen av referenssubstanser i syfte att användas som biomarkörer för att i urin kunna detektera drogmissbruk. Referenssubstanserna kan även användas för att studera metaboliternas farmakologiska egenskaper vilket kan leda till en djupare förståelse kring toxiciteten hos modersubstanserna.
Book Synopsis A Formal Approach to Discourse Anaphora by : Bonnie Lynn Webber
Download or read book A Formal Approach to Discourse Anaphora written by Bonnie Lynn Webber and published by Routledge. This book was released on 2016-11-18 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1979, this book starts from the perspective that dealing with anaphoric language can be decomposed into two complementary tasks: 1. identifying what a text potentially makes available for anaphoric reference and 2. constraining the candidate set of a given anaphoric expression down to one possible choice. The author argues there is an intimate connection between formal sentential analysis and the synthesis of an appropriate conceptual model of the discourse. Some of the issues with the creation of this conceptual model are discussed in the second chapter, which follows a background to the thesis that catalogues the types of anaphoric expression available in English and lists the types of things that can be referred to anaphorically. The third and fourth chapters examine two types of anaphoric expression that do not refer to non-linguistic entities. The final chapter details three areas into which this research could potentially be extended. This book will be of interest to students of linguistics.
Book Synopsis Black Mamba Rising by : Alfred Temba Qabula
Download or read book Black Mamba Rising written by Alfred Temba Qabula and published by . This book was released on 1986 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Proteolytic Enzymes by : Gertrude E. Perlmann
Download or read book Proteolytic Enzymes written by Gertrude E. Perlmann and published by Gulf Professional Publishing. This book was released on 1970 with total page 968 pages. Available in PDF, EPUB and Kindle. Book excerpt: The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.
Book Synopsis The SAGE Handbook of Drug & Alcohol Studies by : Kim Wolff
Download or read book The SAGE Handbook of Drug & Alcohol Studies written by Kim Wolff and published by SAGE. This book was released on 2016-10-18 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions from leading international academics across the biological sciences, this handbook takes a critical look at the key contemporary issues and debates in the field. The 31 chapters are divided into four parts: Part I Determination of Substance Misuse Part II PK and PD in Relation to Patterns of Use Part III Detection and Treatment of Drug and Alcohol Use Part IV Controversies and New Approaches This Handbook is an excellent reference text for the growing number of academics, students, scientists and practitioners in the drug and alcohol studies community, and will be a vital resource to the allied professions involved in work-place drug testing, clinical toxicology, and forensic science.
Book Synopsis Hayes' Principles and Methods of Toxicology by : A. Wallace Hayes
Download or read book Hayes' Principles and Methods of Toxicology written by A. Wallace Hayes and published by CRC Press. This book was released on 2023-07-03 with total page 2143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hayes’ Principles and Methods of Toxicology has long been established as a reliable and informative reference for the concepts, methodologies, and assessments integral to toxicology. The new edition contains updated and new chapters with the addition of new authors while maintaining the same high standards that have made this book a benchmark resource in the field. Key Features: The comprehensive yet concise coverage of various aspects of fundamental and applied toxicology makes this book a valuable resource for educators, students, and professionals. Questions provided at the end of each chapter allow readers to test their knowledge and understanding of the material covered. All chapters have been updated and over 60 new authors have been added to reflect the dynamic nature of toxicological sciences New topics in this edition include Safety Assessment of Cosmetics and Personal Care Products, The Importance of the Dose/Rate Response, Novel Approaches and Alternative Models, Epigenetic Toxicology, and an Expanded Glossary. The volume is divided into 4 major sections, addressing fundamental principles of toxicology (Section I. "Principles of Toxicology"), major classes of established chemical hazards (Section II. "Agents"), current methods used for the assessment of various endpoints indicative of chemical toxicity (Section III. "Methods"), as well as toxicology of specific target systems and organs (Section IV. "Organ- and System-Specific Toxicology"). This volume will be a valuable tool for the audience that wishes to broaden their understanding of hazards and mechanisms of toxicity and to stay on top of the emerging methods and concepts of the rapidly advancing field of toxicology and risk assessment.
Book Synopsis The Cambridge Companion to World Literature by : Ben Etherington
Download or read book The Cambridge Companion to World Literature written by Ben Etherington and published by Cambridge University Press. This book was released on 2018-10-31 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Cambridge Companion to World Literature introduces the significant ideas and practices of world literary studies. It provides a lucid and accessible account of the fundamental issues and concepts in world literature, including the problems of imagining the totality of literature; comparing literary works across histories, cultures and languages; and understanding how literary production is affected by forces such as imperialism and globalization. The essays demonstrate how detailed critical engagements with particular literary texts call forth differing conceptions of world literature, and, conversely, how theories of world literature shape our practices of readings. Subjects covered include cosmopolitanism, transnationalism, internationalism, scale and systems, sociological criticism, translation, scripts, and orality. This book also includes original analyses of genres and forms, ranging from tragedy to the novel and graphic fiction, lyric poetry to the short story and world cinema.
Book Synopsis Handbook of Venoms and Toxins of Reptiles by : Stephen P. Mackessy
Download or read book Handbook of Venoms and Toxins of Reptiles written by Stephen P. Mackessy and published by CRC Press. This book was released on 2021-05-24 with total page 681 pages. Available in PDF, EPUB and Kindle. Book excerpt: A decade after publication of the first edition, Handbook of Venoms and Toxins of Reptiles responds to extensive changes in the field of toxinology to endure as the most comprehensive review of reptile venoms on the market. The six sections of this new edition, which has nearly doubled in size, complement the original handbook by presenting current information from many of the leading researchers and physicians in toxinology, with topics ranging from functional morphology, evolution and ecology to crystallography, -omics technologies, drug discovery and more. With the recent recognition by the World Health Organization of snakebite as a neglected tropical disease, the section on snakebite has been expanded and includes several chapters dealing with the problem broadly and with new technologies and the promises these new approaches may hold to counter the deleterious effects of envenomation. This greatly expanded handbook offers a unique resource for biologists, biochemists, toxicologists, physicians, clinicians, and epidemiologists, as well as informed laypersons interested in the biology of venomous reptiles, the biochemistry and molecular biology of venoms, and the effects and treatment of human envenomation.
Download or read book Wildlife Review written by and published by . This book was released on 1984 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Registry of Toxic Effects of Chemical Substances by :
Download or read book Registry of Toxic Effects of Chemical Substances written by and published by . This book was released on 1987 with total page 1026 pages. Available in PDF, EPUB and Kindle. Book excerpt:
