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Extracellular Recording Approaches
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Book Synopsis Extracellular Recording Approaches by : Roy V. Sillitoe
Download or read book Extracellular Recording Approaches written by Roy V. Sillitoe and published by Humana. This book was released on 2018-06-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents techniques and recently developments in extracellular recording. The chapters in this book explore topics such as mouse, rat and zebrafish models; extracellular recordings on human cognition; single-unit recordings and multi-electrode arrays; and recordings in perinatal and early developing mice. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and authoritative, Extracellular Recording Approaches is a valuable resource that provides readers with up-to-date applications and methods to study brain regions involved in sensory, motor, and cognitive functions.
Book Synopsis Basic Electrophysiological Methods by : Ellen Covey
Download or read book Basic Electrophysiological Methods written by Ellen Covey and published by Oxford University Press. This book was released on 2015-02-25 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Electrophysiological Methods provides a concise and easy-to-read guide on a selection of the most important contemporary electrophysiological techniques, their implementation, applications, and ways in which they can be combined and integrated with neuroscientific techniques. Intended for students, postdocs, and faculty with a basic neuroscience background, this text will not obscure the relevant technical details with textbook neuroscience tutorials as many other books do. Instead, each chapter provides a conscientious overview of the underlying theory -- a comprehensive description of equipment, materials, methods, data management, and analysis -- a troubleshooting guide, and a list of frequently asked questions. No book or online resource can function as strictly a DIY set of instructions on how to implement a complex technique. However, this book provides a fundamental and accessible set of information intended to form a foundation prior to, during, and after hands-on experience and training, greatly facilitating the initial learning process and subsequent fine-tuning of technical details.
Book Synopsis Current Laboratory Methods in Neuroscience Research by : Huangui Xiong
Download or read book Current Laboratory Methods in Neuroscience Research written by Huangui Xiong and published by Springer. This book was released on 2016-08-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Laboratory Methods in Neuroscience Research is a research manual for both students and seasoned researchers. It focuses on commonly-used techniques employed in neuroscience research, presented in a simple, step-by-step manner for laboratory use. The manual also offers a “blueprint” for bench-to-bedside research designed to facilitate multidisciplinary neuroscience pursuits. Sections include coverage of neurohistological techniques, in vitro preparations, leukocyte isolation and application in neuroscience, standard laboratory nucleic acid and protein detections, nanomedicine, bioimaging, neuroelectrophysiology, immunohistochemistry and autoradiography, analysis of gene expression, and animal models.
Book Synopsis Encyclopedia of Psychopharmacology by : Ian Stolerman
Download or read book Encyclopedia of Psychopharmacology written by Ian Stolerman and published by Springer Science & Business Media. This book was released on 2010-07-31 with total page 1433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is a broad overview of the central topics and issues in psychopharmacology, biological psychiatry and behavioral neurosciences, with information about developments in the field, including novel drugs and technologies. The more than 2000 entries are written by leading experts in pharmacology and psychiatry and comprise in-depth essays, illustrated with full-color figures, and are presented in a lucid style.
Book Synopsis Neurobiology of Motor Control by : Scott L. Hooper
Download or read book Neurobiology of Motor Control written by Scott L. Hooper and published by John Wiley & Sons. This book was released on 2017-09-05 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: A multi-disciplinary look at the current state of knowledge regarding motor control and movement—from molecular biology to robotics The last two decades have seen a dramatic increase in the number of sophisticated tools and methodologies for exploring motor control and movement. Multi-unit recordings, molecular neurogenetics, computer simulation, and new scientific approaches for studying how muscles and body anatomy transform motor neuron activity into movement have helped revolutionize the field. Neurobiology of Motor Control brings together contributions from an interdisciplinary group of experts to provide a review of the current state of knowledge about the initiation and execution of movement, as well as the latest methods and tools for investigating them. The book ranges from the findings of basic scientists studying model organisms such as mollusks and Drosophila, to biomedical researchers investigating vertebrate motor production to neuroengineers working to develop robotic and smart prostheses technologies. Following foundational chapters on current molecular biological techniques, neuronal ensemble recording, and computer simulation, it explores a broad range of related topics, including the evolution of motor systems, directed targeted movements, plasticity and learning, and robotics. Explores motor control and movement in a wide variety of organisms, from simple invertebrates to human beings Offers concise summaries of motor control systems across a variety of animals and movement types Explores an array of tools and methodologies, including electrophysiological techniques, neurogenic and molecular techniques, large ensemble recordings, and computational methods Considers unresolved questions and how current scientific advances may be used to solve them going forward Written specifically to encourage interdisciplinary understanding and collaboration, and offering the most wide-ranging, timely, and comprehensive look at the science of motor control and movement currently available, Neurobiology of Motor Control is a must-read for all who study movement production and the neurobiological basis of movement—from molecular biologists to roboticists.
Book Synopsis Principles of Electrical Neural Interfacing by : Liang Guo
Download or read book Principles of Electrical Neural Interfacing written by Liang Guo and published by Springer Nature. This book was released on 2021-09-29 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook fills a gap to supply students with the fundamental principles and tools they need to perform the quantitative analyses of the neuroelectrophysiological approaches, including both conventional and emerging ones, prevalently used in neuroscience research and neuroprosthetics. The content grows out of a course on Neuroengineering and Neuroprosthetics, which the author has taught already several times. The key problems the author addresses include (1) the universal operating mechanisms of neuroelectrophysiological approaches, (2) proper configuration of each approach, and (3) proper interpretation of the resulting signals. Efforts are made both to extract the universal principles underlying this common class of approaches and discern the unique properties of each individual approach. To address these important problems, equivalent electrical circuit modeling and signal analysis are used to unravel the functioning mechanisms and principles and provide sound interpretations to the associated signals and phenomena. This book aims to derive analytical solutions to these equivalent circuits, which can offer clear and complete mechanistic insights to the underlying biophysics.
Book Synopsis Electrophysiological Recording Techniques by : Robert P. Vertes
Download or read book Electrophysiological Recording Techniques written by Robert P. Vertes and published by Humana Press. This book was released on 2010-11-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applying neurophysiological methods to the study of brain-behavior relationships proved to be a major advance in the early days of neuroscience research. Considerable technological progress has been made very recently, and the impact on modern neuroscience will be invaluable. In Electrophysiological Recording Techniques, experts in the field present a current view of the widespread application of electrophysiological methods to the study of the brain and to the problem of brain-behavior relationships. The book has been organized to display the range of modern neurophysiological methods ranging from the recordings of single neurons and neuronal ensembles to recordings of field potentials within discrete brain regions and across multiple brain areas. Many of the chapters also address the major challenge of applying the appropriate methods to analyze and interpret neurophysiological recording data. As a volume in the popular Neuromethods series, the chapters provide authoritative reviews of many commonly used approaches in the field today in both the basic research level and in clinical settings. Practical and up-to-date, Electrophysiological Recording Techniques serves as a key reference volume for researchers working in this ever-changing and vital field.
Book Synopsis Handbook of Neural Activity Measurement by : Romain Brette
Download or read book Handbook of Neural Activity Measurement written by Romain Brette and published by Cambridge University Press. This book was released on 2012-09-06 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Underlying principles of the various techniques are explained, enabling neuroscientists to extract meaningful information from their measurements.
Book Synopsis Introduction to Electrophysiological Methods and Instrumentation by : Franklin Bretschneider
Download or read book Introduction to Electrophysiological Methods and Instrumentation written by Franklin Bretschneider and published by Academic Press. This book was released on 2018-11-13 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Electrophysiological Methods and Instrumentation, Second Edition covers all topics of interest to electrophysiologists, neuroscientists and neurophysiologists, from the reliable penetration of cells and the behavior and function of the equipment, to the mathematical tools available for analyzing data. It discusses the pros and cons of techniques and methods used in electrophysiology and how to avoid pitfalls. Although the basics of electrophysiological techniques remain the principal purpose of this second edition, it now integrates several current developments, including, amongst others, automated recording for high throughput screening and multimodal recordings to correlate electrical activity with other physiological parameters collected by optical means. This book provides the electrophysiologist with the tools needed to understand his or her equipment and how to acquire and analyze low-voltage biological signals. Introduces possibilities and solutions, along with the problems, pitfalls, and artefacts of equipment and electrodes Discusses the particulars of recording from brain tissue slices, oocytes and planar bilayers Describes optical methods pertinent to electrophysiological practice Presents the fundamentals of signal processing of analogue signals, spike trains and single channel recordings, along with procedures for signal recording and processing Includes appendices on electrical safety and foundations of useful mathematical tools
Book Synopsis Methods for NEURAL ENSEMBLE RECORDINGS by : Miguel A. L. Nicolelis
Download or read book Methods for NEURAL ENSEMBLE RECORDINGS written by Miguel A. L. Nicolelis and published by CRC Press. This book was released on 2019-07-17 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroscientists have long recognized the importance of understanding the underlying principles of information processing by large populations of neurons. Methods for Neural Ensemble Recordings explores methods for using electrophysiological techniques for monitoring the concurrent activity of ensembles of single neurons. Since current methods allow one to simultaneously record the extracellular activity of up to 100-150 neurons for days or even weeks, neural ensemble recordings have been used to address long-standing issues in development, learning, memory, sensorimotor integration, sensory information processing, and neuronal plasticity. EXAMINES THE MANY POSSIBLE APPLICATIONS FOR THIS REVOLUTIONARY METHOD Each chapter offers a step-by-step description for the implementation of a particular technique or experimental paradigm employing simultaneous multiple electrode recordings. The techniques described can be used in applications that impact a large group of life scientists, including: drug screening (pharmacology) in both in vitro and in vivo preparations developmental studies and studies of neuronal plasticity chronic monitoring of neuronal function in behavioral studies physiological monitoring of neuronal activity in cell cultures and brain slices physiological monitoring of neuronal activity in neurons trafected with genetic vectors chronic monitoring of physiological changes in populations of neurons during learning of new sensorimotor and cognitive tasks
Book Synopsis Methods for Neural Ensemble Recordings by : Miguel A. L. Nicolelis
Download or read book Methods for Neural Ensemble Recordings written by Miguel A. L. Nicolelis and published by CRC Press. This book was released on 2007-12-03 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensively updated and expanded, this second edition of a bestseller distills the current state-of-the-science and provides the nuts and bolts foundation of the methods involved in this rapidly growing science. With contributions from pioneering researchers, it includes microwire array design for chronic neural recordings, new surgical techniques for chronic implantation, microelectrode microstimulation of brain tissue, multielectrode recordings in the somatosensory system and during learning, as well as recordings from the central gustatory-reward pathways. It explores the use of Brain-Machine Interface to restore neurological function and proposes conceptual and technical approaches to human neural ensemble recordings in the future.
Book Synopsis Single Neuron Studies of the Human Brain by : Itzhak Fried
Download or read book Single Neuron Studies of the Human Brain written by Itzhak Fried and published by MIT Press. This book was released on 2014-06-13 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Foundational studies of the activities of spiking neurons in the awake and behaving human brain and the insights they yield into cognitive and clinical phenomena. In the last decade, the synergistic interaction of neurosurgeons, engineers, and neuroscientists, combined with new technologies, has enabled scientists to study the awake, behaving human brain directly. These developments allow cognitive processes to be characterized at unprecedented resolution: single neuron activity. Direct observation of the human brain has already led to major insights into such aspects of brain function as perception, language, sleep, learning, memory, action, imagery, volition, and consciousness. In this volume, experts document the successes, challenges, and opportunity in an emerging field. The book presents methodological tutorials, with chapters on such topics as the surgical implantation of electrodes and data analysis techniques; describes novel insights into cognitive functions including memory, decision making, and visual imagery; and discusses insights into diseases such as epilepsy and movement disorders gained from examining single neuron activity. Finally, contributors consider future challenges, questions that are ripe for investigation, and exciting avenues for translational efforts. Contributors Ralph Adolphs, William S. Anderson, Arjun K. Bansal, Eric J. Behnke, Moran Cerf, Jonathan O. Dostrovsky, Emad N. Eskandar, Tony A. Fields, Itzhak Fried, Hagar Gelbard-Sagiv, C. Rory Goodwin, Clement Hamani, Chris Heller, Mojgan Hodaie, Matthew Howard III, William D. Hutchison, Matias Ison, Hiroto Kawasaki, Christof Koch, Rüdiger Köhling, Gabriel Kreiman, Michel Le Van Quyen, Frederick A. Lenz, Andres M. Lozano, Adam N. Mamelak, Clarissa Martinez-Rubio, Florian Mormann, Yuval Nir, George Ojemann, Shaun R. Patel, Sanjay Patra, Linda Philpott, Rodrigo Quian Quiroga, Ian Ross, Ueli Rutishauser, Andreas Schulze-Bonhage, Erin M. Schuman, Demetrio Sierra-Mercado, Richard J. Staba, Nanthia Suthana, William Sutherling, Travis S. Tierney, Giulio Tononi, Oana Tudusciuc, Charles L. Wilson
Book Synopsis Methods in Neuroendocrinology by : Louis D. Van de Kar
Download or read book Methods in Neuroendocrinology written by Louis D. Van de Kar and published by CRC Press. This book was released on 2020-04-28 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes some of the many different disciplines that are involved in investigations of neuroendocrine control mechanisms. It is intended for students, pre- and post-doctoral fellows, medical residents and others who are interested in neuroendocrine research.
Book Synopsis A Thinking Approach to Physiology by : Ian N. Sabir
Download or read book A Thinking Approach to Physiology written by Ian N. Sabir and published by World Scientific. This book was released on 2008 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whereas other fields continue to become more complex and specialized, physiology happily remains an area that can still be understood by thinking from first principles. However, given the increasing quantity of information available today, it is easy to become overly concerned with details and give in to the temptation to memorize rather than understand. In this concise book, the authors convey their enthusiasm for physiology and convincingly persuade the reader that with a sound understanding of principles, details often fall effortlessly into place. It is by no means an attempt to produce another comprehensive textbook. Instead, a broad overview of the subject is presented, covering areas that are not given the attention they deserve in other texts whilst purposely omitting those aspects where memorization is an unfortunate necessity.
Book Synopsis Development of Extracellular Electrophysiology Methods for Scalable Neural Recording by : Jacob Gold Bernstein
Download or read book Development of Extracellular Electrophysiology Methods for Scalable Neural Recording written by Jacob Gold Bernstein and published by . This book was released on 2016 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: In order to map the dynamics of neural circuits in mammalian brains, there is a need for tools that can record activity over large volumes of tissue and correctly attribute the recorded signals to the individual neurons that generated them. High-resolution neural activity maps will be critical for the discovery of new principles of neural coding and neural computation, and to test computational models of neural circuits. Extracellular electrophysiology is a neural recording method that has been developed to record from large populations of neurons, but well-known problems with signal attribution pose an existential threat to the viability of further system scaling, as analyses of network function become more sensitive to errors in attribution. A key insight is that blind-source separation algorithms such as Independent Component Analysis may ameliorate problems with signal attribution. These algorithms require recording signals at much finer spatial resolutions than existing probes have accomplished, which places demands on recording system bandwidth. We present several advances to technologies in neural recording systems, and a complete neural recording system designed to investigate the challenges of scaling electrophysiology to whole brain recording. We have developed close-packed microelectrode arrays with the highest density of recording sites yet achieved, for which we built our own data acquisition hardware, developed with a computational architecture specifically designed to scale to over several orders of magnitude. We also present results from validation experiments using colocalized patch clamp recording to obtain ground-truth activity data. This dataset provides immediate insight into the nature of electrophysiological signals and the interpretation of data collected from any electrophysiology recording system. This data is also essential in order to optimize probe development and data analysis algorithms which will one day enable whole-brain activity mapping.
Book Synopsis Neuronal Ensembles by : Howard B. Eichenbaum
Download or read book Neuronal Ensembles written by Howard B. Eichenbaum and published by Wiley-Liss. This book was released on 1998-04-13 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The distributed coding hypothesis —the view that complex cognitive functions such as visual perception or memory formation are the work of large networks of neurons in areas of the cerebral cortex —is widely accepted in contemporary neuroscience. Yet only in recent years have tools emerged that can monitor the electrophysiological activity of neuron ensembles in the cortical areas of awake, behaving animals. The use of these multichannel recording techniques in biological network analysis is changing the way scientists view brain function. These methods also offer the possibility of a direct test of the distributed coding hypothesis. Neuronal Ensembles: Strategies for Recording and Decoding presents a comprehensive treatment of multichannel recording techniques —how to apply them and how to analyze the vast amounts of data they generate. Composed of contributions by leading neuroscientists at the forefront of this technology, the book covers groundbreaking work in multichannel microelectrode technology, analyses of single neuron spike trains, and ensemble analysis of cell populations. The authors outline established techniques, offer practical tips on developing new methods, and share their ideas for further brain research. Topics covered include: Extracellular recording and analysis of neural activity The relationship between neuronal codes and cortical organization Cell assemblies and cognitive function Neuronal population coding Motor cortical information processing Detection and identification of ensemble codes in the motor cortex Ensemble recordings and the nature of stimulus representation in hippocampal cognitive maps Methods, results, and issues related to recording neural ensembles Neuronal ensemble dynamics in the hippocampus and neocortex during sleep and waking Behavioral, electrophysiological, and genetic approaches to the study of synaptic plasticity and memory Neuronal Ensembles: Strategies for Recording and Decoding is an important reference for researchers, graduate students, and postdoctoral fellows in all areas of neuroscience, cognitive neuroscience, and bioengineering.
Book Synopsis Modern Techniques in Neuroscience Research by : Uwe Windhorst
Download or read book Modern Techniques in Neuroscience Research written by Uwe Windhorst and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 1336 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the techniques used in modern neuroscience research with the emphasis on showing how different techniques can optimally be combined in the study of problems that arise at some levels of nervous system organization. This is essentially a working tool for the scientist in the laboratory and clinic, providing detailed step-by-step protocols with tips and recommendations. Most chapters and protocols are organized such that they can be used independently, while cross-references between the chapters, a glossary, a list of suppliers and appendices provide further help.
