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Experimental Study Of Wet Granulation In Fluidized Bed
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Book Synopsis Design and Processing of Particulate Products by : Jim Litster
Download or read book Design and Processing of Particulate Products written by Jim Litster and published by Cambridge University Press. This book was released on 2016-10-20 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique text providing comprehensive coverage of fundamental particle science, processing and technology. Including quantitative tools, real-world case studies and end-of-chapter problems, it is ideal for students in engineering and applied sciences, as well as for practitioners in a range of industries manufacturing particulate products.
Book Synopsis The Science and Engineering of Granulation Processes by : Jim Litster
Download or read book The Science and Engineering of Granulation Processes written by Jim Litster and published by Springer Science & Business Media. This book was released on 2004-03-31 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book had its origins in a meeting between two (relatively) young particle technology researchers on Rehobeth Beach in Delaware in 1992 near the holiday house of Reg Davies (then Director of the Particle Science and Technology Research Center in Dupont). As we played in the sand, we shared an excitement for developments in particle technology, especially particle characterization, that would lead operations such as granulation to be placed on a sound scientific and engineering footing. The immediate outcome from this interaction was the development of new industry short courses in granulation and related topics which we taught together both in Australia and North America. This book follows closely the structure and approaches developed in these courses, particularly the emphasis on particle design in granulation, where the impact of both formulation properties and process variables on product attributes needs to be understood and quantified. The book has been a long time in the making. We have been actively preparing the book for at least five years. Although the chapters have relatively good bibliographies, this book is not a review of the field. Rather it is an attempt by the authors to present a comprehensive engineering approach to granulator design, scale up and operation. It is exciting for us to see the explosion of research interest around the world in this area in the last five to seven years. Some of the most recent work will have to find its way into the second edition.
Book Synopsis Handbook of Pharmaceutical Wet Granulation by : Ajit S. Narang
Download or read book Handbook of Pharmaceutical Wet Granulation written by Ajit S. Narang and published by Academic Press. This book was released on 2018-08-31 with total page 894 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Pharmaceutical Wet Granulation: Theory and Practice in a Quality by Design Paradigm offers a single and comprehensive reference dedicated to all aspects of pharmaceutical wet granulation, taking a holistic approach by combining introductory principles with practical solutions. Chapters are written by international experts across industry, academic and regulatory settings, and cover a wide spectrum of relevant and contemporary wet granulation topics, techniques and processes. The books' focus on process analytical technology, quality by design principles, granulation equipment, modeling, scale-up, control and real time release makes it a timely and valuable resource for all those involved in pharmaceutical wet granulation. - Discusses fundamentals of theory and current industrial practice in the field of wet granulation, including product and process design and role of material properties in wet granulation - Examines the modern evolution of wet granulation through current topics such as established and novel process analytical technologies (PATs), and product development and scale-up paradigms - Written for scientists working within the pharmaceutical industry, as well as academics, regulatory officials and equipment vendors who provide PAT tools and granulation equipment
Book Synopsis Handbook of Pharmaceutical Granulation Technology by : Dilip M. Parikh
Download or read book Handbook of Pharmaceutical Granulation Technology written by Dilip M. Parikh and published by CRC Press. This book was released on 2021-05-11 with total page 905 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theoretical discussions covering granulation and engineering perspectives. Covers new advances in expert systems, process modelling and bioavailability Chapters on emerging technologies in particle engineering Updated Current research and developments in granulation technologies
Book Synopsis Granularity in Materials Science by : George Kyzas
Download or read book Granularity in Materials Science written by George Kyzas and published by BoD – Books on Demand. This book was released on 2018-10-24 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: Granular materials are a special topic of recent research and are a milestone of science and technology. These materials are very simple: they are large conglomerations of discrete macroscopic particles. Granular materials have a broad area of development, which is growing rapidly day by day. Their impact on commercial applications and academia and education is huge. The basic points of this book are the important applications and properties of granular materials. For example, special mention is made of rheological points, shapes, and civil engineering aspects.
Book Synopsis Pharmaceutical Blending and Mixing by : P. J. Cullen
Download or read book Pharmaceutical Blending and Mixing written by P. J. Cullen and published by John Wiley & Sons. This book was released on 2015-07-20 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written in four parts, this book provides a dedicated and in-depth reference for blending within the pharmaceutical manufacturing industry. It links the science of blending with regulatory requirements associated with pharmaceutical manufacture. The contributors are a combination of leading academic and industrial experts, who provide an informed and industrially relevant perspective of the topic. This is an essential book for the pharmaceutical manufacturing industry, and related academic researchers in pharmaceutical science and chemical and mechanical engineering.
Book Synopsis Size Enlargement by Agglomeration by : Wolfgang Pietsch
Download or read book Size Enlargement by Agglomeration written by Wolfgang Pietsch and published by . This book was released on 1991-09-27 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although agglomeration has long been used in the making of bricks and the recovery of coal particles, scientific investigation in this area only began in the 1950s. Presents for the first time the fundamentals of agglomeration science, the technology related to it and its various applications in modern industry. There is a thorough review of methods of experimental investigation and analysis and a detailed section on industrial size enlargement equipment and processes.
Book Synopsis How to Optimize Fluid Bed Processing Technology by : Dilip Parikh
Download or read book How to Optimize Fluid Bed Processing Technology written by Dilip Parikh and published by Academic Press. This book was released on 2017-04-04 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: How to Optimize Fluid Bed Processing Technology: Part of the Expertise in Pharmaceutical Process Technology Series addresses the important components of fluid bed granulation, providing answers to problems that commonly arise and using numerous practical examples and case studies as reference. This book covers the theoretical concepts involved in fluidization, also providing a description of the choice and functionality of equipment. Additional chapters feature key aspects of the technology, including formulation requirements, process variables, process scale-up, troubleshooting, new development, safety, and process evaluation. Given its discussion of theoretical principles and practical solutions, this is a go-to resource for all those scientists and new researchers working with fluid bed granulation as a unit operation. - Written by an expert in the field with several years of experience in product development, manufacturing, plant operations, and process engineering - Illustrates when fluid bed granulation is needed, when to use less common fluid bed granulation methods, and the advantages of fluid bed granulation when compared to other granulation techniques - Offers troubleshooting tips and practical advice for scientists working with this technique
Book Synopsis Predictive Modeling of Pharmaceutical Unit Operations by : Preetanshu Pandey
Download or read book Predictive Modeling of Pharmaceutical Unit Operations written by Preetanshu Pandey and published by Woodhead Publishing. This book was released on 2016-09-26 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of modeling and simulation tools is rapidly gaining prominence in the pharmaceutical industry covering a wide range of applications. This book focuses on modeling and simulation tools as they pertain to drug product manufacturing processes, although similar principles and tools may apply to many other areas. Modeling tools can improve fundamental process understanding and provide valuable insights into the manufacturing processes, which can result in significant process improvements and cost savings. With FDA mandating the use of Quality by Design (QbD) principles during manufacturing, reliable modeling techniques can help to alleviate the costs associated with such efforts, and be used to create in silico formulation and process design space. This book is geared toward detailing modeling techniques that are utilized for the various unit operations during drug product manufacturing. By way of examples that include case studies, various modeling principles are explained for the nonexpert end users. A discussion on the role of modeling in quality risk management for manufacturing and application of modeling for continuous manufacturing and biologics is also included. - Explains the commonly used modeling and simulation tools - Details the modeling of various unit operations commonly utilized in solid dosage drug product manufacturing - Practical examples of the application of modeling tools through case studies - Discussion of modeling techniques used for a risk-based approach to regulatory filings - Explores the usage of modeling in upcoming areas such as continuous manufacturing and biologics manufacturingBullet points
Book Synopsis Pharmaceutical Experimental Design by : Gareth A. Lewis
Download or read book Pharmaceutical Experimental Design written by Gareth A. Lewis and published by CRC Press. This book was released on 1998-09-10 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This useful reference describes the statistical planning and design of pharmaceutical experiments, covering all stages in the development process-including preformulation, formulation, process study and optimization, scale-up, and robust process and formulation development.Shows how to overcome pharmaceutical, technological, and economic constraint
Book Synopsis Computational Models for Polydisperse Particulate and Multiphase Systems by : Daniele L. Marchisio
Download or read book Computational Models for Polydisperse Particulate and Multiphase Systems written by Daniele L. Marchisio and published by Cambridge University Press. This book was released on 2013-03-28 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: All-inclusive introduction to polydisperse multiphase flows linking theory to practice through numerous real-world examples and MATLAB® scripts for key algorithms.
Book Synopsis Handbook of Industrial Drying by : Arun S. Mujumdar
Download or read book Handbook of Industrial Drying written by Arun S. Mujumdar and published by CRC Press. This book was released on 2014-07-11 with total page 1334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Fourth Edition book includes 12 new chapters covering computational fluid dynamic simulation; solar, impingement, and pulse combustion drying; drying of fruits, vegetables, sugar, biomass, and coal; physicochemical aspects of sludge drying; and life-cycle assessment of drying systems. Addressing commonly encountered dryers as well as innovative dryers with future potential, the fully revised text not only delivers a comprehensive treatment of the current state of the art, but also serves as a consultative reference for streamlining industrial drying operations to increase energy efficiency and cost-effectiveness.
Book Synopsis Process Modelling and Simulation by : César de Prada
Download or read book Process Modelling and Simulation written by César de Prada and published by MDPI. This book was released on 2019-09-23 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since process models are nowadays ubiquitous in many applications, the challenges and alternatives related to their development, validation, and efficient use have become more apparent. In addition, the massive amounts of both offline and online data available today open the door for new applications and solutions. However, transforming data into useful models and information in the context of the process industry or of bio-systems requires specific approaches and considerations such as new modelling methodologies incorporating the complex, stochastic, hybrid and distributed nature of many processes in particular. The same can be said about the tools and software environments used to describe, code, and solve such models for their further exploitation. Going well beyond mere simulation tools, these advanced tools offer a software suite built around the models, facilitating tasks such as experiment design, parameter estimation, model initialization, validation, analysis, size reduction, discretization, optimization, distributed computation, co-simulation, etc. This Special Issue collects novel developments in these topics in order to address the challenges brought by the use of models in their different facets, and to reflect state of the art developments in methods, tools and industrial applications.
Book Synopsis Formulation and Analytical Development for Low-Dose Oral Drug Products by : Jack Zheng
Download or read book Formulation and Analytical Development for Low-Dose Oral Drug Products written by Jack Zheng and published by John Wiley & Sons. This book was released on 2009-02-09 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are unique challenges in the formulation, manufacture, analytical chemistry, and regulatory requirements of low-dose drugs. This book provides an overview of this specialized field and combines formulation, analytical, and regulatory aspects of low-dose development into a single reference book. It describes analytical methodologies like dissolution testing, solid state NMR, Raman microscopy, and LC-MS and presents manufacturing techniques such as granulation, compaction, and compression. Complete with case studies and a discussion of regulatory requirements, this is a core reference for pharmaceutical scientists, regulators, and graduate students.
Book Synopsis Pharmaceutical Experimental Design And Interpretation by : N. Anthony Armstrong
Download or read book Pharmaceutical Experimental Design And Interpretation written by N. Anthony Armstrong and published by CRC Press. This book was released on 2002-09-11 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work provides a description of the principles of experimental design and their application to pharmaceutical research. It includes worked examples taken from a wide variety of pharmaceutical techniques and processes.
Book Synopsis Mesoscale Modeling in Chemical Engineering Part I by :
Download or read book Mesoscale Modeling in Chemical Engineering Part I written by and published by Academic Press. This book was released on 2015-11-26 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing Mesoscales of Multiscale Problems in Chemical Engineering, a volume in the Advances in Chemical Engineering series provides readers with the personal views of recognized authorities who present assessments of the state-of-the-art in the field and help readers develop an understanding of its further evolution. Subjects covered in the book are not limited to the classical chemical engineering disciplines. Contributions connecting chemical engineering to related scientific fields, either providing a fundamental basis or introducing new concepts and tools, are encouraged. This volume aims to create a balance between well developed areas such as process industry, transformation of materials, energy, and environmental issues, and areas where applications of chemical engineering are more recent or emerging. - Contains reviews by leading authorities in their respective areas - Provides up-to-date reviews of the latest techniques in the modeling of catalytic processes - Includes a broad mix of US and European authors, as well as academic/industrial/research institute perspectives - Provides discussions on the connections between computation and experimental methods
Book Synopsis Pharmaceutical Dosage Forms - Tablets by : Larry L. Augsburger
Download or read book Pharmaceutical Dosage Forms - Tablets written by Larry L. Augsburger and published by CRC Press. This book was released on 2016-04-19 with total page 1558 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ultimate goal of drug product development is to design a system that maximizes the therapeutic potential of the drug substance and facilitates its access to patients. Pharmaceutical Dosage Forms: Tablets, Third Edition is a comprehensive resource of the design, formulation, manufacture, and evaluation of the tablet dosage form, an