Evolving Methods for Macromolecular Crystallography

Download Evolving Methods for Macromolecular Crystallography PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1402063148
Total Pages : 192 pages
Book Rating : 4.4/5 (2 download)

DOWNLOAD NOW!


Book Synopsis Evolving Methods for Macromolecular Crystallography by : Randy J. Read

Download or read book Evolving Methods for Macromolecular Crystallography written by Randy J. Read and published by Springer Science & Business Media. This book was released on 2007-06-25 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume draws on the expertise of leaders in the field of macromolecular crystallography to illuminate the dramatic developments that are accelerating progress in structural biology. Their contributions span the range of techniques from crystallization through data collection, structure solution and analysis. The book shows how modern high-throughput methods are contributing to a deeper understanding of medical problems.

Evolving Methods for Macromolecular Crystallography

Download Evolving Methods for Macromolecular Crystallography PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1402063164
Total Pages : 193 pages
Book Rating : 4.4/5 (2 download)

DOWNLOAD NOW!


Book Synopsis Evolving Methods for Macromolecular Crystallography by : Randy J. Read

Download or read book Evolving Methods for Macromolecular Crystallography written by Randy J. Read and published by Springer Science & Business Media. This book was released on 2007-07-20 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume draws on the expertise of leaders in the field of macromolecular crystallography to illuminate the dramatic developments that are accelerating progress in structural biology. Their contributions span the range of techniques from crystallization through data collection, structure solution and analysis. The book shows how modern high-throughput methods are contributing to a deeper understanding of medical problems.

Evolving Methods for Macromolecular Crystallography

Download Evolving Methods for Macromolecular Crystallography PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 248 pages
Book Rating : 4.:/5 (847 download)

DOWNLOAD NOW!


Book Synopsis Evolving Methods for Macromolecular Crystallography by : Randy J. Read

Download or read book Evolving Methods for Macromolecular Crystallography written by Randy J. Read and published by . This book was released on 2005 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Macromolecular Crystallography

Download Macromolecular Crystallography PDF Online Free

Author :
Publisher : Oxford University Press
ISBN 13 : 0198520972
Total Pages : 293 pages
Book Rating : 4.1/5 (985 download)

DOWNLOAD NOW!


Book Synopsis Macromolecular Crystallography by : Mark R. Sanderson

Download or read book Macromolecular Crystallography written by Mark R. Sanderson and published by Oxford University Press. This book was released on 2007-08-23 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Macromolecular crystallography is the study of macromolecules using X-ray crystallographic techniques to determine their molecular structure. This title synthesises contributions from a team of internationally recognized leaders, offering chapters on conventional and high-throughput methods.

Evolutionary methods for macromolecular crystallography

Download Evolutionary methods for macromolecular crystallography PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 248 pages
Book Rating : 4.:/5 (441 download)

DOWNLOAD NOW!


Book Synopsis Evolutionary methods for macromolecular crystallography by :

Download or read book Evolutionary methods for macromolecular crystallography written by and published by . This book was released on 2005 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Introduction to Macromolecular Crystallography

Download Introduction to Macromolecular Crystallography PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118210638
Total Pages : 284 pages
Book Rating : 4.1/5 (182 download)

DOWNLOAD NOW!


Book Synopsis Introduction to Macromolecular Crystallography by : Alexander McPherson

Download or read book Introduction to Macromolecular Crystallography written by Alexander McPherson and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and approachable introduction to crystallography — now updated in a valuable new edition The Second Edition of this well-received book continues to offer the most concise, authoritative, and easy-to-follow introduction to the field of crystallography. Dedicated to providing a complete, basic presentation of the subject that does not assume a background in physics or math, the book's content flows logically from basic principles to methods, such as those for solving phase problems, interpretation of Patterson maps and the difference Fourier method, the fundamental theory of diffraction and the properties of crystals, and applications in determining macromolecular structure. This new edition includes a vast amount of carefully updated materials, as well as two completely new chapters on recording and compiling X-ray data and growing crystals of proteins and other macromolecules. Richly illustrated throughout to clarify difficult concepts, this book takes a non-technical approach to crystallography that is ideal for professionals and graduate students in structural biology, biophysics, biochemistry, and molecular biology who are studying the subject for the first time.

Methods in Macromolecular Crystallography

Download Methods in Macromolecular Crystallography PDF Online Free

Author :
Publisher : IOS Press
ISBN 13 : 9781586030803
Total Pages : 220 pages
Book Rating : 4.0/5 (38 download)

DOWNLOAD NOW!


Book Synopsis Methods in Macromolecular Crystallography by : North Atlantic Treaty Organization. Scientific Affairs Division

Download or read book Methods in Macromolecular Crystallography written by North Atlantic Treaty Organization. Scientific Affairs Division and published by IOS Press. This book was released on 2001 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains 20 papers from two courses ("Methods for Macromolecular Crystallography" and "Chemical Prospective in Crystallography of Molecular Biology") held during the late spring of 2000 in Reice, Italy. The papers discuss crystals, synchrotrons, detector development, data processing, ab initio phasing and high and low resolution, molecular placement, experimental phase measurement, density modification methods, map improvements, interpretation of electron density maps, automatic structure determination, and the dissection of ultra-high resolution structures. c. Book News Inc.

Advancing Methods for Biomolecular Crystallography

Download Advancing Methods for Biomolecular Crystallography PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 9400762321
Total Pages : 360 pages
Book Rating : 4.4/5 (7 download)

DOWNLOAD NOW!


Book Synopsis Advancing Methods for Biomolecular Crystallography by : Randy Read

Download or read book Advancing Methods for Biomolecular Crystallography written by Randy Read and published by Springer. This book was released on 2013-04-03 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents a snapshot of the state of the art of modern biomolecular crystallography, from crystallisation through structure determination and even interactive presentation on the web. Methods driving the latest automated structure determination pipelines are explained, as well as how to deal with problems such as crystal pathologies that still demand expert analysis. These methods are illustrated through their application to problems of great biological interest, such as the molecular machinery underlying the complement pathway, the mechanism of action of monoamine oxidase inhibitors, and the structure of the eukaryotic ribosome. Complementary approaches, such as neutron diffraction, small angle X-ray scattering, coherent diffraction and computational modelling, are also explored.

Macromolecular Crystallization and Crystal Perfection

Download Macromolecular Crystallization and Crystal Perfection PDF Online Free

Author :
Publisher : Oxford University Press (UK)
ISBN 13 : 0199213259
Total Pages : 234 pages
Book Rating : 4.1/5 (992 download)

DOWNLOAD NOW!


Book Synopsis Macromolecular Crystallization and Crystal Perfection by : Naomi E Chayen

Download or read book Macromolecular Crystallization and Crystal Perfection written by Naomi E Chayen and published by Oxford University Press (UK). This book was released on 2010-03-25 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structural biology is key to our understanding of the mechanisms of biological processes. This book describes current methods and future frontiers in crystal growth and use of X-ray and Neutron crystallography, in the context of the very successful current automation of crystallization and generation of synchrotron X-ray and neutron beams.

Molecular Docking for Computer-Aided Drug Design

Download Molecular Docking for Computer-Aided Drug Design PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128223138
Total Pages : 522 pages
Book Rating : 4.1/5 (282 download)

DOWNLOAD NOW!


Book Synopsis Molecular Docking for Computer-Aided Drug Design by : Mohane S. Coumar

Download or read book Molecular Docking for Computer-Aided Drug Design written by Mohane S. Coumar and published by Academic Press. This book was released on 2021-02-17 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Docking for Computer-Aided Drug Design: Fundamentals, Techniques, Resources and Applications offers in-depth coverage on the use of molecular docking for drug design. The book is divided into three main sections that cover basic techniques, tools, web servers and applications. It is an essential reference for students and researchers involved in drug design and discovery. Covers the latest information and state-of-the-art trends in structure-based drug design methodologies Includes case studies that complement learning Consolidates fundamental concepts and current practice of molecular docking into one convenient resource

Comprehensive Medicinal Chemistry III

Download Comprehensive Medicinal Chemistry III PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0128032014
Total Pages : 4609 pages
Book Rating : 4.1/5 (28 download)

DOWNLOAD NOW!


Book Synopsis Comprehensive Medicinal Chemistry III by :

Download or read book Comprehensive Medicinal Chemistry III written by and published by Elsevier. This book was released on 2017-06-03 with total page 4609 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Medicinal Chemistry III, Eight Volume Set provides a contemporary and forward-looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery. Reviews the strategies, technologies, principles, and applications of modern medicinal chemistry Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs

Structural Biology in Drug Discovery

Download Structural Biology in Drug Discovery PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118900502
Total Pages : 1367 pages
Book Rating : 4.1/5 (189 download)

DOWNLOAD NOW!


Book Synopsis Structural Biology in Drug Discovery by : Jean-Paul Renaud

Download or read book Structural Biology in Drug Discovery written by Jean-Paul Renaud and published by John Wiley & Sons. This book was released on 2020-01-09 with total page 1367 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biology in Drug Discovery: Methods, Techniques, and Practices describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field. The combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that: Presents the benefits, limitations, and potentiality of major techniques in the field such as X-ray crystallography, NMR, neutron crystallography, cryo-EM, mass spectrometry and other biophysical techniques, and computational structural biology Includes detailed chapters on druggability, allostery, complementary use of thermodynamic and kinetic information, and powerful approaches such as structural chemogenomics and fragment-based drug design Emphasizes the need for the in-depth biophysical characterization of protein targets as well as of therapeutic proteins, and for a thorough quality assessment of experimental structures Illustrates advances in the field of established therapeutic targets like kinases, serine proteinases, GPCRs, and epigenetic proteins, and of more challenging ones like protein-protein interactions and intrinsically disordered proteins

Progress in the Chemistry of Organic Natural Products 100

Download Progress in the Chemistry of Organic Natural Products 100 PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 3319052756
Total Pages : 602 pages
Book Rating : 4.3/5 (19 download)

DOWNLOAD NOW!


Book Synopsis Progress in the Chemistry of Organic Natural Products 100 by : A. D. Kinghorn

Download or read book Progress in the Chemistry of Organic Natural Products 100 written by A. D. Kinghorn and published by Springer. This book was released on 2014-11-17 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: The volumes of this classic series, now referred to simply as "Zechmeister" after its founder, L. Zechmeister, have appeared under the Springer Imprint ever since the series' inauguration in 1938. It is therefore not really surprising to find out that the list of contributing authors, who were awarded a Nobel Prize, is quite long: Kurt Alder, Derek H.R. Barton, George Wells Beadle, Dorothy Crowfoot-Hodgkin, Otto Diels, Hans von Euler-Chelpin, Paul Karrer, Luis Federico Leloir, Linus Pauling, Vladimir Prelog, with Walter Norman Haworth and Adolf F.J. Butenandt serving as members of the editorial board. The volumes contain contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occurring substances ranging from small molecules to biopolymers. Each contribution is written by a recognized authority in his field and provides a comprehensive and up-to-date review of the topic in question. Addressed to biologists, technologists and chemists alike, the series can be used by the expert as a source of information and literature citations and by the non-expert as a means of orientation in a rapidly developing discipline.

Phasing in Crystallography

Download Phasing in Crystallography PDF Online Free

Author :
Publisher : Oxford University Press, USA
ISBN 13 : 0199686998
Total Pages : 433 pages
Book Rating : 4.1/5 (996 download)

DOWNLOAD NOW!


Book Synopsis Phasing in Crystallography by : Carmelo Giacovazzo

Download or read book Phasing in Crystallography written by Carmelo Giacovazzo and published by Oxford University Press, USA. This book was released on 2014 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book describes phasing techniques in modern crystallography. The main text is dedicated to their simple description, and further mathematical details are contained in the appendices. Practical aspects are described for each specific method, making it a useful tool for the daily work of practising crystallographers.

Macromolecular Crystallography Protocols, Volume 1

Download Macromolecular Crystallography Protocols, Volume 1 PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1597452092
Total Pages : 283 pages
Book Rating : 4.5/5 (974 download)

DOWNLOAD NOW!


Book Synopsis Macromolecular Crystallography Protocols, Volume 1 by : Sylvie Doublie

Download or read book Macromolecular Crystallography Protocols, Volume 1 written by Sylvie Doublie and published by Springer Science & Business Media. This book was released on 2008-02-04 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Macromolecular Crystallography Protocols, now in two volumes, examines major developments that have occurred since publication of the acclaimed first edition nearly a decade ago. Volume 1 is composed of detailed protocols for the preparation and optimization of crystals. Volume 2 complements the first volume by addressing laboratory techniques for crystal handling and structural characterization. The volume concludes with a survey of available crystallographic software.

Macromolecular Crystallography, Part C

Download Macromolecular Crystallography, Part C PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0080497098
Total Pages : 405 pages
Book Rating : 4.0/5 (84 download)

DOWNLOAD NOW!


Book Synopsis Macromolecular Crystallography, Part C by : Charles W. Carter Jr.

Download or read book Macromolecular Crystallography, Part C written by Charles W. Carter Jr. and published by Elsevier. This book was released on 2003-12-15 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Accurate molecular structures are vital for rational drug design and for structure-based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding. * Methodological methods in crystals* Methodological methods data analysis

Biochemical Pathways and Environmental Responses in Plants: Part A

Download Biochemical Pathways and Environmental Responses in Plants: Part A PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0323955622
Total Pages : 450 pages
Book Rating : 4.3/5 (239 download)

DOWNLOAD NOW!


Book Synopsis Biochemical Pathways and Environmental Responses in Plants: Part A by :

Download or read book Biochemical Pathways and Environmental Responses in Plants: Part A written by and published by Elsevier. This book was released on 2022-10-22 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical Pathways and Environmental Responses in Plants, Part A, Volume 676 in the Methods in Enzymology series highlights new advances in the field with this new volume presenting interesting chapters on topics such as Structure, function, and engineering of plant polyketide synthases, A sensitive LC-MS/MS assay for enzymatic characterization of methylthioalkylmalate synthase involved in glucosinolate side-chain elongation, Assaying formate-tetrahydrofolate ligase with monoglutamylated and polyglutamylated substrates using a fluorescence-HPLC based assay, An Approach to Nearest Neighbor Analysis of Pigmented Protein Complexes by Using Chemical Crosslinking in Combination with Mass Spectrometry, and much more. Other chapters cover Biochemical characterization of plant aromatic aminotransferases, Functional Analysis of Phosphoethanolamine N-methyltransferase (PMT) in Plants and Parasites, A structure-guided computational screening approach for predicting plant enzyme-metabolite interactions, Plant metacaspase: an example of microcrystal structure determination and analysis, Biocatalytic system for comparative assessment of functional association of cytochrome P450 monooxygenases with their redox partners, Dirigent Protein Family Function and Structure, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Methods in Enzymology series Includes the latest information on Biochemical pathways and environmental responses in plants