Evolutionary Methods In Biotechnology

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Evolutionary Methods in Biotechnology

Author : Susanne Brakmann
Publisher : John Wiley & Sons
ISBN 13 : 3527604626
Total Pages : 227 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Evolutionary Methods in Biotechnology by : Susanne Brakmann

Download or read book Evolutionary Methods in Biotechnology written by Susanne Brakmann and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Miniturization and high throughput assay technology have brought the power of molecular evolution to the bioscience laboratory. Applied wisely, the evolutionary approach can quickly yield the desired result even where other methods have failed. From library generation by random or directed mutagenesis to screening and selection techniques -- the crucial steps for successful evolutionary biotechnology are described in detail in this practical guide that also includes valuable troubleshooting hints on frequently encountered problems. Modern methods for the surface display of peptides and proteins, selective enrichment of nucleic acid aptamers and high-throughput screening of industrial biocatalysts are explained, and computer-based methods for in silico protein and RNA engineering are described as an alternative to in vitro approaches. A special section covers the patenting regulations with regard to biotechnological innovations derived from directed evolution. As an added bonus, a CD-ROM is included that contains software tools for library design, selection of mutagenesis positions, and various predictive algorithms. In short, this practice oriented handbook is an indispensable tool for every scientist working in this interdisciplinary research area.

Sequence — Evolution — Function

Author : Eugene V. Koonin
Publisher : Springer Science & Business Media
ISBN 13 : 1475737831
Total Pages : 482 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Sequence — Evolution — Function by : Eugene V. Koonin

Download or read book Sequence — Evolution — Function written by Eugene V. Koonin and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.

Environmental Epigenetics

Author : L. Joseph Su
Publisher : Springer
ISBN 13 : 1447166787
Total Pages : 327 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Environmental Epigenetics by : L. Joseph Su

Download or read book Environmental Epigenetics written by L. Joseph Su and published by Springer. This book was released on 2015-05-18 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Molecular Evolution and Phylogenetics

Author : Masatoshi Nei
Publisher : Oxford University Press
ISBN 13 : 0199881227
Total Pages : 444 pages
Book Rating : 4.1/5 (998 download)

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Book Synopsis Molecular Evolution and Phylogenetics by : Masatoshi Nei

Download or read book Molecular Evolution and Phylogenetics written by Masatoshi Nei and published by Oxford University Press. This book was released on 2000-07-27 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth. Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees, statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical examples using the computer program MEGA2 that is provided.

Concepts of Biology

Author : Samantha Fowler
Publisher :
ISBN 13 : 9781739015503
Total Pages : 0 pages
Book Rating : 4.0/5 (155 download)

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Book Synopsis Concepts of Biology by : Samantha Fowler

Download or read book Concepts of Biology written by Samantha Fowler and published by . This book was released on 2023-05-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Black & white print. Concepts of Biology is designed for the typical introductory biology course for nonmajors, covering standard scope and sequence requirements. The text includes interesting applications and conveys the major themes of biology, with content that is meaningful and easy to understand. The book is designed to demonstrate biology concepts and to promote scientific literacy.

Evolution of Translational Omics

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309224187
Total Pages : 354 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Evolution of Translational Omics by : Institute of Medicine

Download or read book Evolution of Translational Omics written by Institute of Medicine and published by National Academies Press. This book was released on 2012-09-13 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Safety of Genetically Engineered Foods

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309166152
Total Pages : 254 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Safety of Genetically Engineered Foods by : National Research Council

Download or read book Safety of Genetically Engineered Foods written by National Research Council and published by National Academies Press. This book was released on 2004-07-08 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps.

Genetics of Adaptation

Author : Rodney Mauricio
Publisher : Springer Science & Business Media
ISBN 13 : 1402038364
Total Pages : 207 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Genetics of Adaptation by : Rodney Mauricio

Download or read book Genetics of Adaptation written by Rodney Mauricio and published by Springer Science & Business Media. This book was released on 2005-07-20 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: An enduring controversy in evolutionary biology is the genetic basis of adaptation. Darwin emphasized "many slight differences" as the ultimate source of variation to be acted upon by natural selection. In the early 1900’s, this view was opposed by "Mendelian geneticists", who emphasized the importance of "macromutations" in evolution. The Modern Synthesis resolved this controversy, concluding that mutations in genes of very small effect were responsible for adaptive evolution. A decade ago, Allen Orr and Jerry Coyne reexamined the evidence for this neo-Darwinian view and found that both the theoretical and empirical basis for it were weak. Orr and Coyne encouraged evolutionary biologists to reexamine this neglected question: what is the genetic basis of adaptive evolution? In this volume, a new generation of biologists have taken up this challenge. Using advances in both molecular genetic and statistical techniques, evolutionary geneticists have made considerable progress in this emerging field. In this volume, a diversity of examples from plant and animal studies provides valuable information for those interested in the genetics and evolution of complex traits.

Evolutionary Genomics and Systems Biology

Author : Gustavo Caetano-Anollés
Publisher : Wiley-Blackwell
ISBN 13 : 0470570407
Total Pages : 330 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Evolutionary Genomics and Systems Biology by : Gustavo Caetano-Anollés

Download or read book Evolutionary Genomics and Systems Biology written by Gustavo Caetano-Anollés and published by Wiley-Blackwell. This book was released on 2010-07-08 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, authoritative look at an emergent area in post-genomic science, Evolutionary genomics is an up-and-coming, complex field that attempts to explain the biocomplexity of the living world. Evolutionary Genomics and Systems Biology is the first full-length book to blend established and emerging concepts in bioinformatics, evolution, genomics, and structural biology, with the integrative views of network and systems biology. Three key aspects of evolutionary genomics and systems biology are covered in clear detail: the study of genomic history, i.e., understanding organismal evolution at the genomic level; the study of macromolecular complements, which encompasses the evolution of the protein and RNA machinery that propels life; and the evolutionary and dynamic study of wiring diagrams—macromolecular components in interaction—in the context of genomic complements. The book also features: A solid, comprehensive treatment of phylogenomics, the evolution of genomes, and the evolution of biological networks, within the framework of systems biology A special section on RNA biology—translation, evolution of structure, and micro RNA and regulation of gene expression Chapters on the mapping of genotypes to phenotypes, the role of information in biology, protein architecture and biological function, chromosomal rearrangements, and biological networks and disease Contributions by leading authorities on each topic Evolutionary Genomics and Systems Biology is an ideal book for students and professionals in genomics, bioinformatics, evolution, structural biology, complexity, origins of life, systematic biology, and organismal diversity, as well as those individuals interested in aspects of biological sciences as they interface with chemistry, physics, and computer science and engineering.

Biotechnology of Microbial Enzymes

Author : Goutam Brahmachari
Publisher : Academic Press
ISBN 13 : 0128037466
Total Pages : 634 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Biotechnology of Microbial Enzymes by : Goutam Brahmachari

Download or read book Biotechnology of Microbial Enzymes written by Goutam Brahmachari and published by Academic Press. This book was released on 2016-07-21 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnology of Microbial Enzymes: Production, Biocatalysis and Industrial Applications provides a complete survey of the latest innovations on microbial enzymes, highlighting biotechnological advances in their production and purification along with information on successful applications as biocatalysts in several chemical and industrial processes under mild and green conditions. Applications of microbial enzymes in food, feed, and pharmaceutical industries are given particular emphasis. The application of recombinant DNA technology within industrial fermentation and the production of enzymes over the last 20 years have produced a host of useful chemical and biochemical substances. The power of these technologies results in novel transformations, better enzymes, a wide variety of applications, and the unprecedented development of biocatalysts through the ongoing integration of molecular biology methodology, all of which is covered insightfully and in-depth within the book. - Features research on microbial enzymes from basic science through application in multiple industry sectors for a comprehensive approach - Includes information on metabolic pathway engineering, metagenomic screening, microbial genomes, extremophiles, rational design, directed evolution, and more - Provides a holistic approach to the research of microbial enzymes

Biotechnology: Concepts, Methodologies, Tools, and Applications

Author : Management Association, Information Resources
Publisher : IGI Global
ISBN 13 : 152258904X
Total Pages : 2220 pages
Book Rating : 4.5/5 (225 download)

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Book Synopsis Biotechnology: Concepts, Methodologies, Tools, and Applications by : Management Association, Information Resources

Download or read book Biotechnology: Concepts, Methodologies, Tools, and Applications written by Management Association, Information Resources and published by IGI Global. This book was released on 2019-06-07 with total page 2220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnology can be defined as the manipulation of biological process, systems, and organisms in the production of various products. With applications in a number of fields such as biomedical, chemical, mechanical, and civil engineering, research on the development of biologically inspired materials is essential to further advancement. Biotechnology: Concepts, Methodologies, Tools, and Applications is a vital reference source for the latest research findings on the application of biotechnology in medicine, engineering, agriculture, food production, and other areas. It also examines the economic impacts of biotechnology use. Highlighting a range of topics such as pharmacogenomics, biomedical engineering, and bioinformatics, this multi-volume book is ideally designed for engineers, pharmacists, medical professionals, practitioners, academicians, and researchers interested in the applications of biotechnology.

Biological Evolution and Statistical Physics

Author : M. Lässig
Publisher : Springer
ISBN 13 : 3540456929
Total Pages : 340 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Biological Evolution and Statistical Physics by : M. Lässig

Download or read book Biological Evolution and Statistical Physics written by M. Lässig and published by Springer. This book was released on 2008-01-11 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This set of lecture notes gives a first coherent account of a novel aspect of the living world that can be called biological information. The book presents both a pedagogical and state-of-the art roadmap of this rapidly evolving area and covers the whole field, from information which is encoded in the molecular genetic code to the description of large-scale evolution of complex species networks. The book will prove useful for all those who work at the interface of biology, physics and information science.

Biotechnology for Biofuel Production and Optimization

Author : Carrie A Eckert
Publisher : Elsevier
ISBN 13 : 0081000537
Total Pages : 574 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Biotechnology for Biofuel Production and Optimization by : Carrie A Eckert

Download or read book Biotechnology for Biofuel Production and Optimization written by Carrie A Eckert and published by Elsevier. This book was released on 2016-01-19 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnology for Biofuel Production and Optimization is the compilation of current research findings that cover the entire process of biofuels production from manipulation of genes and pathways to organisms and renewable feedstocks for efficient biofuel production as well as different cultivation techniques and process scale-up considerations. This book captures recent breakthroughs in the interdisciplinary areas of systems and synthetic biology, metabolic engineering, and bioprocess engineering for renewable, cleaner sources of energy. - Describes state-of-the-art engineering of metabolic pathways for the production of a variety of fuel molecules - Discusses recent advances in synthetic biology and metabolic engineering for rational design, construction, evaluation of novel pathways and cell chassis - Covers genome engineering technologies to address complex biofuel-tolerant phenotypes for enhanced biofuel production in engineered chassis - Presents the use of novel microorganisms and expanded substrate utilization strategies for production of targeted fuel molecules - Explores biohybrid methods for harvesting bioenergy - Discusses bioreactor design and optimization of scale-up

The Evolving World

Author : David P. Mindell
Publisher : Harvard University Press
ISBN 13 : 0674041089
Total Pages : 352 pages
Book Rating : 4.6/5 (74 download)

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Book Synopsis The Evolving World by : David P. Mindell

Download or read book The Evolving World written by David P. Mindell and published by Harvard University Press. This book was released on 2009-07-01 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the 150 years since Darwin, evolutionary biology has proven as essential as it is controversial, a critical concept for answering questions about everything from the genetic code and the structure of cells to the reproduction, development, and migration of animal and plant life. But today, as David P. Mindell makes undeniably clear in The Evolving World, evolutionary biology is much more than an explanatory concept. It is indispensable to the world we live in. This book provides the first truly accessible and balanced account of how evolution has become a tool with applications that are thoroughly integrated, and deeply useful, in our everyday lives and our societies, often in ways that we do not realize. When we domesticate wild species for agriculture or companionship; when we manage our exposure to pathogens and prevent or control epidemics; when we foster the diversity of species and safeguard the functioning of ecosystems: in each of these cases, Mindell shows us, evolutionary biology applies. It is at work when we recognize that humans represent a single evolutionary family with variant cultures but shared biological capabilities and motivations. And last but not least, we see here how evolutionary biology comes into play when we use knowledge of evolution to pursue justice within the legal system and to promote further scientific discovery through education and academic research. More than revealing evolution's everyday uses and value, The Evolving World demonstrates the excitement inherent in its applications--and convinces us as never before that evolutionary biology has become absolutely necessary for human existence.

Evolution Made to Order

Author : Helen Anne
Publisher : University of Chicago Press
ISBN 13 : 022639011X
Total Pages : 296 pages
Book Rating : 4.2/5 (263 download)

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Book Synopsis Evolution Made to Order by : Helen Anne

Download or read book Evolution Made to Order written by Helen Anne and published by University of Chicago Press. This book was released on 2016-11-11 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant breeders have long sought technologies to extend human control over nature. Early in the twentieth century, this led some to experiment with startlingly strange tools like x-ray machines, chromosome-altering chemicals, and radioactive elements. Contemporary reports celebrated these mutation-inducing methods as ways of generating variation in plants on demand. Speeding up evolution, they imagined, would allow breeders to genetically engineer crops and flowers to order. Creating a new food crop or garden flower would soon be as straightforward as innovating any other modern industrial product. In Evolution Made to Order, Helen Anne Curry traces the history of America’s pursuit of tools that could intervene in evolution. An immersive journey through the scientific and social worlds of midcentury genetics and plant breeding and a compelling exploration of American cultures of innovation, Evolution Made to Order provides vital historical context for current worldwide ethical and policy debates over genetic engineering.

Microscopic Techniques in Biotechnology

Author : Michael Hoppert
Publisher : John Wiley & Sons
ISBN 13 : 3527605231
Total Pages : 342 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Microscopic Techniques in Biotechnology by : Michael Hoppert

Download or read book Microscopic Techniques in Biotechnology written by Michael Hoppert and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on all current applications, this book presents the various methods as well as their suitability and limitations for a specific question. One particular highlight is the presentation of all basic information on the structure of the relevant objects, thus allowing readers to choose the most suitable applications for any specific problem. They will also find in-depth background information on structure-function relationships, plus descriptions of sample preparations with respect to a particular technique and the necessary equipment. The whole is rounded off with an overview of the future application potential for devices and applications of upcoming interest in biotechnology.

Teaching About Evolution and the Nature of Science

Author : National Academy of Sciences
Publisher : National Academies Press
ISBN 13 : 0309063647
Total Pages : 150 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Teaching About Evolution and the Nature of Science by : National Academy of Sciences

Download or read book Teaching About Evolution and the Nature of Science written by National Academy of Sciences and published by National Academies Press. This book was released on 1998-05-06 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today many school students are shielded from one of the most important concepts in modern science: evolution. In engaging and conversational style, Teaching About Evolution and the Nature of Science provides a well-structured framework for understanding and teaching evolution. Written for teachers, parents, and community officials as well as scientists and educators, this book describes how evolution reveals both the great diversity and similarity among the Earth's organisms; it explores how scientists approach the question of evolution; and it illustrates the nature of science as a way of knowing about the natural world. In addition, the book provides answers to frequently asked questions to help readers understand many of the issues and misconceptions about evolution. The book includes sample activities for teaching about evolution and the nature of science. For example, the book includes activities that investigate fossil footprints and population growth that teachers of science can use to introduce principles of evolution. Background information, materials, and step-by-step presentations are provided for each activity. In addition, this volume: Presents the evidence for evolution, including how evolution can be observed today. Explains the nature of science through a variety of examples. Describes how science differs from other human endeavors and why evolution is one of the best avenues for helping students understand this distinction. Answers frequently asked questions about evolution. Teaching About Evolution and the Nature of Science builds on the 1996 National Science Education Standards released by the National Research Councilâ€"and offers detailed guidance on how to evaluate and choose instructional materials that support the standards. Comprehensive and practical, this book brings one of today's educational challenges into focus in a balanced and reasoned discussion. It will be of special interest to teachers of science, school administrators, and interested members of the community.