Author : Sapna Rawal
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (133 download)
Book Synopsis Evaluating the Clinical Impact of Timing of Aneurysmal Treatment Following Subarachnoid Hemorrhage by : Sapna Rawal
Download or read book Evaluating the Clinical Impact of Timing of Aneurysmal Treatment Following Subarachnoid Hemorrhage written by Sapna Rawal and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The projects in this thesis addressed the knowledge gap regarding optimal timing of aneurysm treatment following subarachnoid hemorrhage (SAH) by evaluating whether earlier aneurysm treatment improves clinical outcomes. This was first examined in a meta-analysis synthesizing evidence from observational studies on timing of endovascular coiling of ruptured aneurysms. The results informed a cohort study using Ontario registry and administrative data evaluating timing of surgical or endovascular aneurysm treatment in SAH, where early treatment within one calendar date of SAH was compared to later treatment. The use of administrative data for evaluation of outcomes in SAH was bolstered by external validation of the Nationwide Inpatient Sample Subarachnoid Hemorrhage Severity Score (NIS-SSS), as well as a modified version of the NIS-SSS (m-NIS-SSS). The meta-analysis of observational studies demonstrated a possible but inconsistent benefit of treatment within 1 day of SAH. Treatment.