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Evaluating Synergy
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Download or read book Evaluating Synergy written by Ming Tan and published by Wiley. This book was released on 2024-04-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Containing the historical and statistical information necessary to choose an analysis method and successful drug combination, Evaluating Synergy provides a systematic introduction of statistical methods for optimally designing and analyzing combination studies in cancer, anti-viral, and other therapeutic areas. This practical guide provides scientists in translational research, data analysts, and statisticians in cancer research with a detailed discussion on the challenging case of three or multi-drug combinations. Numerous examples accompany a presentation that illustrates experimental design considerations for modern drug analysis.
Book Synopsis Synergy for Clinical Excellence by : Roberta Kaplow
Download or read book Synergy for Clinical Excellence written by Roberta Kaplow and published by Jones & Bartlett Learning. This book was released on 2005 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential reference for nursing students in developing and implementing the competencies necessary in caring for critically ill patients. Includes sample test questions relevant to the model that will assist nursing students in preparing for certification through AACN.
Book Synopsis OECD Reviews of Evaluation and Assessment in Education Synergies for Better Learning An International Perspective on Evaluation and Assessment by : OECD
Download or read book OECD Reviews of Evaluation and Assessment in Education Synergies for Better Learning An International Perspective on Evaluation and Assessment written by OECD and published by OECD Publishing. This book was released on 2013-04-11 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report provides an international comparative analysis and policy advice to countries on how evaluation and assessment arrangements can be embedded within a consistent framework to improve the quality, equity and efficiency of school education.
Book Synopsis Drug Synergism and Dose-Effect Data Analysis by : Ronald J. Tallarida
Download or read book Drug Synergism and Dose-Effect Data Analysis written by Ronald J. Tallarida and published by CRC Press. This book was released on 2000-07-21 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Not since this author's bestselling Manual of Pharmacologic Calculation-long out of print-has there been a reference available for drug data analysis, and even that work did not deal with drug combinations. Although pharmacologists and most other scientists know what synergism is, mainstream textbooks tend to neglect it as a quantitative topic. Few
Book Synopsis Synergy Value and Strategic Management by : Stefano Garzella
Download or read book Synergy Value and Strategic Management written by Stefano Garzella and published by Springer. This book was released on 2016-08-29 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses synergy management, which poses an important challenge for firms, advisors and practitioners involved in mergers and acquisitions (M&A). Synergy plays a key role in M&A contexts, both in the decision-making process and, subsequently, in the integration phase. However, despite the fact that synergy value is commonly regarded as one of the key success factors in M&A, research shows that firms generally fail to achieve the expected synergy. The extant literature is characterized by a lack of comprehensive models of synergy management: the assessment of synergy value remains a “black box” for scholars and practitioners alike. The authors provide a comprehensive framework for synergy management by integrating findings from prior research and various disciplines. The framework highlights the main dimensions of synergy management in mergers and acquisitions, common pitfalls, and new models and tools for avoiding them. As such, the book enriches the M&A literature, offers new insights for scholars, and provides valuable guidelines for practitioners involved in synergy management.
Book Synopsis In Search of Synergy in Small Group Performance by : James R. Larson
Download or read book In Search of Synergy in Small Group Performance written by James R. Larson and published by Psychology Press. This book was released on 2010 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume critically evaluates more than a century of empirical research on the effectiveness of small, task-performing groups, and offers a fresh look at the costs and benefits of collaborative work arrangements. The central question taken up by this book is whether -- and under what conditions -- interaction among group members leads to better performance than would otherwise be achieved simply by combining the separate efforts of an equal number of people who work independently. This question is considered with respect to a range of tasks (idea-generation, problem solving, judgment, and decision-making) and from several different process perspectives (learning and memory, motivation, and member diversity). As a framework for assessing the empirical literature, the book introduces the concept of 'synergy.' Synergy refers to an objective gain in performance that is attributable to group interaction. Further, it distinguishes between weak and strong synergy, which are performance gains of different magnitude. The book highlights the currently available empirical evidence for both weak and strong synergy, identifies the conditions that seem necessary to produce each, and suggests where the search for synergy might best be directed in the future. The book is at once a high-level introduction to the field, a review of the field's history, and a scholarly critique of the current state-of-the-art. As such, it is essential reading for graduate students, advanced undergraduate students, and researchers interested in group dynamics generally -- and small group performance in particular.
Book Synopsis In Search of Synergy in Small Group Performance by : James R. Larson, Jr.
Download or read book In Search of Synergy in Small Group Performance written by James R. Larson, Jr. and published by Psychology Press. This book was released on 2013-01-11 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume critically evaluates more than a century of empirical research on the effectiveness of small, task-performing groups, and offers a fresh look at the costs and benefits of collaborative work arrangements. The central question taken up by this book is whether -- and under what conditions -- interaction among group members leads to better performance than would otherwise be achieved simply by combining the separate efforts of an equal number of people who work independently. This question is considered with respect to a range of tasks (idea-generation, problem solving, judgment, and decision-making) and from several different process perspectives (learning and memory, motivation, and member diversity). As a framework for assessing the empirical literature, the book introduces the concept of 'synergy.' Synergy refers to an objective gain in performance that is attributable to group interaction. Further, it distinguishes between weak and strong synergy, which are performance gains of different magnitude. The book highlights the currently available empirical evidence for both weak and strong synergy, identifies the conditions that seem necessary to produce each, and suggests where the search for synergy might best be directed in the future. The book is at once a high-level introduction to the field, a review of the field's history, and a scholarly critique of the current state-of-the-art. As such, it is essential reading for graduate students, advanced undergraduate students, and researchers interested in group dynamics generally -- and small group performance in particular.
Book Synopsis The Synergy Trap by : Mark L. Sirower
Download or read book The Synergy Trap written by Mark L. Sirower and published by Simon and Schuster. This book was released on 2010-05-11 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: With acquisition activity running into the trillions of dollars, the acquisition alternative continues to be the favorite corporate growth strategy of this generation's executives. Unfortunately, creating shareholder value remains the most elusive outcome of these corporate strategies. After decades of research and billions of dollars paid in advisory fees, why do these major decisions continue to destroy value? Building on his groundbreaking research first cited in Business Week, Mark L. Sirower explains how companies often pay too much -- and predictably never realize the promises of increased performance and competitiveness -- in their quest to acquire other companies. Armed with extensive evidence, Sirower destroys the popular notion that the acquisition premium represents potential value. He provides the first formal and functional definition for synergy -- the specific increases in performance beyond those already expected for companies to achieve independently. Sirower's refreshing nuts-and-bolts analysis of the fundamentals behind acquisition performance cuts sharply through the existing folklore surrounding failed acquisitions, such as lack of "strategic fit" or corporate culture problems, and gives managers the tools to avoid predictable losses in acquisition decisions. Using several detailed examples of recent major acquisitions and through his masterful integration and extension of techniques from finance and business strategy, Sirower reveals: The unique business gamble that acquisitions represent The managerial challenges already embedded in current stock prices The competitive conditions that must be met and the organizational cornerstones that must be in place for any possibility of synergy The precise Required Performance Improvements (RPIs) implicitly embedded in acquisition premiums and the reasons why these RPIs normally dwarf realistic performance gains The seductiveness and danger of sophisticated valuation models so often used by advisers The Synergy Trap is the first exposé of its kind to prove that the tendency of managers to succumb to the "up the ante" philosophy in acquisitions often leads to disastrous ends for their shareholders. Sirower shows that companies must meticulously plan -- and account for huge uncertainties -- before deciding to enter the acquisition game. To date, Sirower's work is the most comprehensive and rigorous, yet practical, analysis of the drivers of acquisition performance. This definitive book will become required reading for managers, corporate directors, consultants, investors, bankers, and academics involved in the mergers and acquisitions arena.
Book Synopsis Synergy in Mergers & Acquisitions by : Stefan Karenfort
Download or read book Synergy in Mergers & Acquisitions written by Stefan Karenfort and published by BoD – Books on Demand. This book was released on 2011 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: The creation of synergy, which is often illustrated as the "2+2=5-effect", is a dominant motive as well as a key success factor for Mergers & Acquisitions (M&A). Inadequate expectations with respect to the synergistic potential can however easily result in an overrated acquisition price. If the planned synergies later fail to materialize, it will be increasingly hard for the acquiring firm to achieve positive value gains for its shareholders. It is therefore vital to obtain a comprehensive understanding of the synergistic potential of a planned M&A project. This issue was addressed with a doctoral thesis investigating the underlying drivers of synergy realization, in particular the concept of business relatedness which describes the similarity of firm attributes, such as product-market presence, resource configuration and supply channel types. Using a quantitative hypothesis-testing survey design, more than 300 M&A consultants worldwide have been invited to evaluate past M&A transactions with respect to their synergistic effects. In contrast to earlier studies, the relatedness of the merging firms is established as a multi-dimensional concept considering various attributes of business relatedness simultaneously. The degree of relatedness is measured using managerial perceptions which is a comparatively new measurement approach transferred from diversification research to the field of M&A. The individual dimensions of relatedness show a different effectiveness concerning synergy realization providing further support to recent contributions which advocate a multi-dimensional conceptualization of business relatedness. The study identifies dimensions of business relatedness and their underlying drivers which are particularly relevant to predictions concerning the synergistic potential. The research project thus makes a valuable contribution to clarify the impact of relatedness on M&A performance and provides important implications for practitioners regarding the eval
Book Synopsis In Search of Synergy in Small Group Performance by : James R. Larson, Jr.
Download or read book In Search of Synergy in Small Group Performance written by James R. Larson, Jr. and published by Psychology Press. This book was released on 2013-01-11 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume critically evaluates more than a century of empirical research on the effectiveness of small, task-performing groups, and offers a fresh look at the costs and benefits of collaborative work arrangements. The central question taken up by this book is whether -- and under what conditions -- interaction among group members leads to better performance than would otherwise be achieved simply by combining the separate efforts of an equal number of people who work independently. This question is considered with respect to a range of tasks (idea-generation, problem solving, judgment, and decision-making) and from several different process perspectives (learning and memory, motivation, and member diversity). As a framework for assessing the empirical literature, the book introduces the concept of 'synergy.' Synergy refers to an objective gain in performance that is attributable to group interaction. Further, it distinguishes between weak and strong synergy, which are performance gains of different magnitude. The book highlights the currently available empirical evidence for both weak and strong synergy, identifies the conditions that seem necessary to produce each, and suggests where the search for synergy might best be directed in the future. The book is at once a high-level introduction to the field, a review of the field's history, and a scholarly critique of the current state-of-the-art. As such, it is essential reading for graduate students, advanced undergraduate students, and researchers interested in group dynamics generally -- and small group performance in particular.
Book Synopsis The Synergy Solution by : Mark Sirower
Download or read book The Synergy Solution written by Mark Sirower and published by Harvard Business Press. This book was released on 2022-03-15 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new M&A bible. Few actions can change the value of a company—and its competitive future—as quickly and dramatically as an acquisition. Yet most companies fail to create shareholder value from these deals, and in many cases they destroy it. It doesn't have to be this way. In The Synergy Solution, Deloitte's Mark Sirower and Jeff Weirens show acquirers how to develop and execute an M&A strategy—end to end—that not only avoids the pitfalls that so many companies fall into but also creates real, long-term shareholder value. This strategy includes how to: Become a prepared "always on" acquirer Test the investment thesis and DCF valuation of a deal Plan for a successful Announcement Day, and properly communicate synergy promises to investors and other stakeholders Realize those promised synergies through integration planning and post-close execution Manage change and build a new, combined organization Sirower and Weirens provide invaluable background to those considering M&A, laying out the issues they have to consider, how to analyze them, and how to plan and execute the deal effectively. They also show those who have already started the process of M&A how to maximize their chances of success. There's an art and a science to getting mergers and acquisitions right, and this powerful book provides the insights and strategies acquirers need to find success at every stage of an often complex and perilous process.
Book Synopsis It Takes a Village: The Expanding Multi-Disciplinary Approach to Brain Metastasis by : Peter Fecci
Download or read book It Takes a Village: The Expanding Multi-Disciplinary Approach to Brain Metastasis written by Peter Fecci and published by Frontiers Media SA. This book was released on 2022-11-22 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Evaluating Socio-economic Programmes by : Commission of the European Communities
Download or read book Evaluating Socio-economic Programmes written by Commission of the European Communities and published by . This book was released on 1999 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Kinesins and Cancer by : Frank Kozielski, FSB
Download or read book Kinesins and Cancer written by Frank Kozielski, FSB and published by Springer. This book was released on 2015-03-02 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: This interdisciplinary volume collates research work on kinesins and cancer. Authors attempt to validate members of the kinesin superfamily as potential targets for drug development in cancer chemotherapy. The work begins by highlighting the importance of kinesins, summarising current knowledge and how they are shown to be crucial for mitosis. Chapters go on to explore how this family of proteins are emerging as a novel target for chemotherapeutic intervention and drug development. Readers will learn how kinesins travel along microtubules to fulfill their many roles in intracellular transport or cell division. Several compounds that inhibit two mitotic kinesins (called Eg5 and CENP-E) have entered Phase I and II clinical trials and are explored in these chapters. Additional mitotic kinesins are currently being validated as drug targets, raising the possibility that the repertoire of kinesin-based drug targets may expand in the future. The book is suitable as a reference standard for the field of kinesins and cancer. It will interest those in academia and pharmaceutical companies, and anyone with an interest in the medical relevance of these proteins, which cutting edge methodologies are now enabling us to understand in astonishing detail.
Book Synopsis Applying Conceptual Models of Nursing by : Dr. Jacqueline Fawcett, PhD, ScD (hon), RN, FAAN, ANEF
Download or read book Applying Conceptual Models of Nursing written by Dr. Jacqueline Fawcett, PhD, ScD (hon), RN, FAAN, ANEF and published by Springer Publishing Company. This book was released on 2016-11-16 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical resource for nursing students, educators, researchers, and practitioners provides content about the conceptual models of nursing that are used as organizing frameworks for nursing practice, quality improvement projects, and research. Chapters break these abstract models down into their core concepts and definitions. Discussions of each model provide examples of practical application so readers can employ these organizing frameworks. This is the only book to apply these models to quality improvement projects, particularly those in DNP programs and clinical agencies. For every conceptual model, diagrams, information boxes, and other visual elements clarify and reinforce information. Each chapter features applications of the conceptual models to a wide variety of examples, including nursing practice assessment and an intervention, a literature review and descriptive qualitative, instrument development, correlational, experimental, and mixed-method studies. Other valuable features include faculty templates for practice, quality improvement, and research methodologies for each conceptual model, along with extensive references. Key Features: Focuses on applying conceptual models in practice Demonstrates how a wide range of nursing conceptual models are applied to nursing practice, quality improvement, and research PowerPoint templates for each conceptual model avaliable to faculty Provides abundant diagrams, boxes, and other visual elements to clarify and reinforce information Includes an extensive list of references for each conceptual model
Book Synopsis CIM Justification and Optimisation by : Sev V Nagalingam
Download or read book CIM Justification and Optimisation written by Sev V Nagalingam and published by CRC Press. This book was released on 2020-11-26 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a justification and optimisation model that is complete enough to capture the important features required for a complex decision-making environment for computer integrated manufacturing investment analysis. The model provides facilities to quantify qualitative attributes.
Book Synopsis Statistical Methods in Drug Combination Studies by : Wei Zhao
Download or read book Statistical Methods in Drug Combination Studies written by Wei Zhao and published by CRC Press. This book was released on 2014-12-19 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: The growing interest in using combination drugs to treat various complex diseases has spawned the development of many novel statistical methodologies. The theoretical development, coupled with advances in statistical computing, makes it possible to apply these emerging statistical methods in in vitro and in vivo drug combination assessments. Howeve
