Différences entre séchage traditionnel et micro-ondes

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ISBN 13 :
Total Pages : 214 pages
Book Rating : 4.:/5 (69 download)

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Book Synopsis Différences entre séchage traditionnel et micro-ondes by : Emilie Taillant

Download or read book Différences entre séchage traditionnel et micro-ondes written by Emilie Taillant and published by . This book was released on 2009 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dans l'industrie pharmaceutique, l'obtention d'un comprimé nécessite, dans la plupart des cas, une étude préalable de granulation humide. C'est une technique largement utilisée pour densifier un mélange pulvérulent et le rendre comprimable ; il s'agit d'un procédé complexe mettant en jeu deux étapes principales, la granulation (en présence d'un liquide de mouillage) puis le séchage, dont la maîtrise est essentielle pour garantir la qualité et la reproductibilité du grain obtenu. La partie bibliographique s'attachera à présenter les différentes méthodes et appareillages permettant l'obtention du grain. La technique de séchage par micro-ondes sera plus détaillée, un paragraphe lui sera consacré. Parmi ces équipements, il existe des mélangeurs-granulateurs-sécheurs (dits MGS), assurant les 2 principales étapes au sein d'une même enceinte. Ce sont ces types d'appareils, les Turbosphères® que nous retrouvons sur le site de Gidy des Laboratoires SERVIER pour la fabrication du Daflon®500mg. La partie pratique de ce travail s'intéressera à l'étude préalable de mise en place du transfert de production d'un MGS avec séchage micro-ondes vers un MGS non équipé, où le séchage se fera de façon traditionnelle (double enveloppe). L'impact de ce changement de méthodologie sur le grain sera plus particulièrement étudié.

Amélioration d'un procédé de fabrication par suivi en temps réel d'opérations de mélange à l'aide d'un spectromètre proche infrarouge

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ISBN 13 :
Total Pages : 144 pages
Book Rating : 4.:/5 (867 download)

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Book Synopsis Amélioration d'un procédé de fabrication par suivi en temps réel d'opérations de mélange à l'aide d'un spectromètre proche infrarouge by : Madjid Meziani

Download or read book Amélioration d'un procédé de fabrication par suivi en temps réel d'opérations de mélange à l'aide d'un spectromètre proche infrarouge written by Madjid Meziani and published by . This book was released on 2013 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: L’approche PAT, par l’outil d’analyse proche infrarouge, permet de suivre le comportement d’un mélange de poudres et plus précisément de définir l’obtention de l’attribut qualité critique, l’homogénéité, conjointement au processus d’analyse traditionnelle, l’HPLC. Ainsi, l’application d’une approche PAT faisant intervenir du proche infrarouge en cours de mélange a permis l’amélioration des procédés de fabrication par optimisation des opérations de pesées, de chargement et de mélange. Pour ce faire, un processus de validation a été déroulé, de l’initiation d’une demande de changement à la clôture de celle-ci, en passant par la réalisation d’essais sur un procédé validé, d’une étude de faisabilité, d’une analyse de risque et d’une validation à proprement parler aboutissant à la rédaction d’un rapport de validation. Ainsi, le suivi en temps réel des opérations de mélange par proche infrarouge a permis de valider les modifications envisagées en apportant une meilleure compréhension, et par conséquent une maîtrise complète des procédés de fabrication considérés.

Industry and Environment

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Publisher :
ISBN 13 :
Total Pages : 336 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Industry and Environment by :

Download or read book Industry and Environment written by and published by . This book was released on 1994 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Contribution à la maitrise des procédés de compression directe au sein d'une unité de fabrication de formes sèches

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ISBN 13 :
Total Pages : 340 pages
Book Rating : 4.:/5 (492 download)

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Book Synopsis Contribution à la maitrise des procédés de compression directe au sein d'une unité de fabrication de formes sèches by : Axelle Billaud

Download or read book Contribution à la maitrise des procédés de compression directe au sein d'une unité de fabrication de formes sèches written by Axelle Billaud and published by . This book was released on 2006 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Soucieuse d'élever le niveau de maîtrise de certains de ses procédés de compression directe, une unité de fabrication de formes sèches d'un laboratoire français a décidé d'entamer une démarche de résolution de problèmes, en raison de difficultés récurrentes de dosages hors normes, de clivage des comprimés et d'augmentation des durées de process. Après avoir développé les caractéristiques et les principes généraux de la fabrication industrielle des comprimés, et plus particulièrement le procédé de compression directe, l'étude des cas pratiques a conduit à identifier les causes responsables des anomalies rencontrées selon une démarche structurée. La mise en place de plans d'actions suite aux conclusions des investigations a visé à revenir aux spécifications en tenant compte des contraintes réglementaires, qualité, techniques et humaines.

QUALIFICATION ET VALIDATION D'UN PROCEDE INDUSTIREL DE FABRICATION D'UNE FORME DERMIQUE

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (49 download)

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Book Synopsis QUALIFICATION ET VALIDATION D'UN PROCEDE INDUSTIREL DE FABRICATION D'UNE FORME DERMIQUE by : CATHERINE.. DUMOUT

Download or read book QUALIFICATION ET VALIDATION D'UN PROCEDE INDUSTIREL DE FABRICATION D'UNE FORME DERMIQUE written by CATHERINE.. DUMOUT and published by . This book was released on 1995 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

VALIDATION D'UN PROCEDE DE FABRICATION D'UNE FORME COMPRIME

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (49 download)

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Book Synopsis VALIDATION D'UN PROCEDE DE FABRICATION D'UNE FORME COMPRIME by : CECILE.. THOMAS

Download or read book VALIDATION D'UN PROCEDE DE FABRICATION D'UNE FORME COMPRIME written by CECILE.. THOMAS and published by . This book was released on 1998 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mise en forme des poudres

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (142 download)

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Book Synopsis Mise en forme des poudres by : célia

Download or read book Mise en forme des poudres written by célia and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Une entreprise pharmaceutique de premier plan en France, cherchant à maintenir sa position de leader à l'échelle nationale et à consolider sa sixième position au niveau mondial, se démarque par son engagement envers l'amélioration de sa performance industrielle, tout en respectant scrupuleusement les réglementations qui régissent l'industrie pharmaceutique, notamment les pharmacopées, les bonnes pratiques de fabrication (BPF) et le code de la santé publique (CSP). Cette entreprise accorde une attention particulière à la réduction des coûts et à l'optimisation des délais de production. Dans cette optique, ce groupe a entrepris un processus d'optimisation des procédés industriels. Face à une augmentation d'environ un quart du nombre de lots à produire au cours de cette année, l'équipe de l'unité autonome de production (UAP) a relevé ce défi en mettant en place un plan d'actions visant à optimiser les procédés et l'organisation, dans le but d'améliorer la performance. L'objectif central de ce projet est d'améliorer les délais de production tout en réduisant les coûts, en ayant recours à des méthodes agiles, notamment la standardisation, la simplification, la digitalisation et une démarche d'amélioration continue qui promeut la culture du Lean Management. Ce mémoire a pour finalité de présenter l'une des nombreuses initiatives d'amélioration continue mises en place. Cette initiative vise à influer positivement sur la productivité d'un flux spécifique de production au sein de l'unité autonome de production.

Faecal Sludge Management

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Publisher : IWA Publishing
ISBN 13 : 1780404735
Total Pages : 428 pages
Book Rating : 4.7/5 (84 download)

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Book Synopsis Faecal Sludge Management by : Linda Strande

Download or read book Faecal Sludge Management written by Linda Strande and published by IWA Publishing. This book was released on 2014-08-15 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is estimated that literally billions of residents in urban and peri-urban areas of Africa, Asia, and Latin America are served by onsite sanitation systems (e.g. various types of latrines and septic tanks). Until recently, the management of faecal sludge from these onsite systems has been grossly neglected, partially as a result of them being considered temporary solutions until sewer-based systems could be implemented. However, the perception of onsite or decentralized sanitation technologies for urban areas is gradually changing, and is increasingly being considered as long-term, sustainable options in urban areas, especially in low- and middle-income countries that lack sewer infrastructures. This is the first book dedicated to faecal sludge management. It compiles the current state of knowledge of the rapidly evolving field of faecal sludge management, and presents an integrated approach that includes technology, management, and planning based on Sandecs 20 years of experience in the field. Faecal Sludge Management: Systems Approach for Implementation and Operation addresses the organization of the entire faecal sludge management service chain, from the collection and transport of sludge, and the current state of knowledge of treatment options, to the final end use or disposal of treated sludge. The book also presents important factors to consider when evaluating and upscaling new treatment technology options. The book is designed for undergraduate and graduate students, and engineers and practitioners in the field who have some basic knowledge of environmental and/or wastewater engineering.

Doing Business 2020

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Publisher : World Bank Publications
ISBN 13 : 1464814414
Total Pages : 241 pages
Book Rating : 4.4/5 (648 download)

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Book Synopsis Doing Business 2020 by : World Bank

Download or read book Doing Business 2020 written by World Bank and published by World Bank Publications. This book was released on 2019-11-21 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Seventeen in a series of annual reports comparing business regulation in 190 economies, Doing Business 2020 measures aspects of regulation affecting 10 areas of everyday business activity.

The Science of metals

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (162 download)

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Book Synopsis The Science of metals by : Zay Jeffries

Download or read book The Science of metals written by Zay Jeffries and published by . This book was released on 1924 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Terra 2008

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Publisher : Getty Publications
ISBN 13 : 1606060430
Total Pages : 438 pages
Book Rating : 4.6/5 (6 download)

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Book Synopsis Terra 2008 by : Leslie Rainer

Download or read book Terra 2008 written by Leslie Rainer and published by Getty Publications. This book was released on 2011-06-14 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Earthen architecture constitutes one of the most diverse forms of cultural heritage and one of the most challenging to preserve. It dates from all periods and is found on all continents but is particularly prevalent in Africa, where it has been a building tradition for centuries. Sites range from ancestral cities in Mali to the palaces of Abomey in Benin, from monuments and mosques in Iran and Buddhist temples on the Silk Road to Spanish missions in California. This volume's sixty-four papers address such themes as earthen architecture in Mali, the conservation of living sites, local knowledge systems and intangible aspects, seismic and other natural forces, the conservation and management of archaeological sites, research advances, and training.

Politics, Property and Production in the West African Sahel

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Publisher : Nordic Africa Institute
ISBN 13 : 9789171064769
Total Pages : 342 pages
Book Rating : 4.0/5 (647 download)

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Book Synopsis Politics, Property and Production in the West African Sahel by : Tor Arve Benjaminsen

Download or read book Politics, Property and Production in the West African Sahel written by Tor Arve Benjaminsen and published by Nordic Africa Institute. This book was released on 2001 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Through a number of case studies from the West African Sahel, this book links and explores natural resources management from the perspectives of politics, property and production.

Biomimicry

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Publisher : Harper Collins
ISBN 13 : 0061958921
Total Pages : 324 pages
Book Rating : 4.0/5 (619 download)

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Book Synopsis Biomimicry by : Janine M. Benyus

Download or read book Biomimicry written by Janine M. Benyus and published by Harper Collins. This book was released on 2009-08-11 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Repackaged with a new afterword, this "valuable and entertaining" (New York Times Book Review) book explores how scientists are adapting nature's best ideas to solve tough 21st century problems. Biomimicry is rapidly transforming life on earth. Biomimics study nature's most successful ideas over the past 3.5 million years, and adapt them for human use. The results are revolutionizing how materials are invented and how we compute, heal ourselves, repair the environment, and feed the world. Janine Benyus takes readers into the lab and in the field with maverick thinkers as they: discover miracle drugs by watching what chimps eat when they're sick; learn how to create by watching spiders weave fibers; harness energy by examining how a leaf converts sunlight into fuel in trillionths of a second; and many more examples. Composed of stories of vision and invention, personalities and pipe dreams, Biomimicry is must reading for anyone interested in the shape of our future.

What is the Code of Conduct for Responsible Fisheries?

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Publisher : Food & Agriculture Org.
ISBN 13 : 9789251045411
Total Pages : 20 pages
Book Rating : 4.0/5 (454 download)

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Book Synopsis What is the Code of Conduct for Responsible Fisheries? by : Food and Agriculture Organization of the United Nations

Download or read book What is the Code of Conduct for Responsible Fisheries? written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2001 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: The actual Code of conduct is also available (1996) (ISBN 9251038341).

Disaster risk reduction in school curricula: case studies from thirty countries

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Publisher : UNESCO
ISBN 13 : 9230010871
Total Pages : 209 pages
Book Rating : 4.2/5 (3 download)

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Book Synopsis Disaster risk reduction in school curricula: case studies from thirty countries by :

Download or read book Disaster risk reduction in school curricula: case studies from thirty countries written by and published by UNESCO. This book was released on 2012 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Knowing our lands and resources

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Publisher : UNESCO Publishing
ISBN 13 : 9231002104
Total Pages : 150 pages
Book Rating : 4.2/5 (31 download)

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Book Synopsis Knowing our lands and resources by : Roué, Marie

Download or read book Knowing our lands and resources written by Roué, Marie and published by UNESCO Publishing. This book was released on 2017-04-03 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Water & Heritage

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Publisher :
ISBN 13 : 9789088903861
Total Pages : 434 pages
Book Rating : 4.9/5 (38 download)

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Book Synopsis Water & Heritage by : Willem Willems

Download or read book Water & Heritage written by Willem Willems and published by . This book was released on 2017-01-15 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Water is vital for life, and its availability has been a concern for mankind throughout the ages. Its presence has always been ascertained in a variety of ways and the development of human society everywhere is connected with various forms of water management. Man also needed to manage water to find protection from its dangers and the need for that is increasing. In the coming decades, the impact of climate change is expected to intensify floods and droughts, affect groundwater resources, raise sea levels, increase pollution and enhance the frequency and magnitude of disasters. Societies around the world are challenged to adapt to these threats to ensure water security, economic prosperity and environmental and cultural sustainability. This book deals with the heritage of water management and the use that was made of water, as well as the impact of water management on heritage. An example of the former may be an ancient irrigation system in the Filipines or in the Middle East that still functions today, while the latter may reflect the importance of maintaining groundwater levels for the preservation of organic remains on archaeological sites or of wooden piles underneath standing buildings. In either case the papers in this book reflect the dynamic nature of water, and hence the equally dynamic relation between water management and heritage. This publication follows up on a Heritage and Water conference in Amsterdam, the first of its kind. Its main purpose is to credibly present the importance and value of heritage and historical experience for water and sustainable development, and vice versa, present the importance of water management for the protection of heritage. It presents evolving insights and concepts about Water and about Heritage from a variety of disciplines, policy and public perspectives illustrated with cases studies and aims to connect decision makers with experts such as engineers, archaeologists, historians, geographers, ecologist and landscape architects