Ethnicity in Drug Development and Therapeutics

Download Ethnicity in Drug Development and Therapeutics PDF Online Free

Author :
Publisher : Cambridge University Press
ISBN 13 : 0521292522
Total Pages : 153 pages
Book Rating : 4.5/5 (212 download)

DOWNLOAD NOW!


Book Synopsis Ethnicity in Drug Development and Therapeutics by : Edyta J. Frackiewicz

Download or read book Ethnicity in Drug Development and Therapeutics written by Edyta J. Frackiewicz and published by Cambridge University Press. This book was released on 2011-06-16 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was first published in 2002. It presents an overview of ethnic and racial differences in response to medications and offers insight into the genetic and non-genetic reasons for these differences. The roles of pharmacogenomics and pharmacogenetics in drug development, regulatory aspects of representing minorities in clinical trials, as well as NIH, ICH and FDA guidelines as they pertain to these issues are examined in detail. Finally, various strategies to increase recruitment and retention of minority populations in clinical trials are considered.

Pharmacogenomics

Download Pharmacogenomics PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0123983037
Total Pages : 510 pages
Book Rating : 4.1/5 (239 download)

DOWNLOAD NOW!


Book Synopsis Pharmacogenomics by : Yui-Wing Francis Lam

Download or read book Pharmacogenomics written by Yui-Wing Francis Lam and published by Academic Press. This book was released on 2013-02-12 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation includes discussions and viewpoints from the academic, regulatory, pharmaceutical, clinical, socio-ethical and economic perspectives. Each chapter presents an overview of the potential or opportunity within the areas discussed and also outlines foreseeable challenges and limitations in moving pharmacogenomics into drug development and direct therapeutic applications. This edited book contains review questions for a more in-depth analysis of the implications of pharmacogenomics and discussion points to generate ideas on best to move the field forward. Clinical pearls and case studies are used to illustrate real-life experiences and both successful and unsuccessful applications. Tables, figures, and annotations are included throughout the book to facilitate understanding and further reference. Multi-contributed book and chapters are written by contributors who are experts in their field Provides perspectives from those involved in all aspects of pharmacogenomics-including academic, regulatory, economic, industry and medical-to illustrate how all of the pieces fit together and where the challenges may be Includes case studies of both successful and unsuccessful applications so readers can consider the potential and challenges in moving the science into drug development and direct therapeutic applications Chapters contain discussion questions and clinical pearls and enable readers to reflect on how to move pharmacogenomics forward and apply these observations and useful tips to their own work and research

Unequal Treatment

Download Unequal Treatment PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 030908265X
Total Pages : 781 pages
Book Rating : 4.3/5 (9 download)

DOWNLOAD NOW!


Book Synopsis Unequal Treatment by : Institute of Medicine

Download or read book Unequal Treatment written by Institute of Medicine and published by National Academies Press. This book was released on 2009-02-06 with total page 781 pages. Available in PDF, EPUB and Kindle. Book excerpt: Racial and ethnic disparities in health care are known to reflect access to care and other issues that arise from differing socioeconomic conditions. There is, however, increasing evidence that even after such differences are accounted for, race and ethnicity remain significant predictors of the quality of health care received. In Unequal Treatment, a panel of experts documents this evidence and explores how persons of color experience the health care environment. The book examines how disparities in treatment may arise in health care systems and looks at aspects of the clinical encounter that may contribute to such disparities. Patients' and providers' attitudes, expectations, and behavior are analyzed. How to intervene? Unequal Treatment offers recommendations for improvements in medical care financing, allocation of care, availability of language translation, community-based care, and other arenas. The committee highlights the potential of cross-cultural education to improve provider-patient communication and offers a detailed look at how to integrate cross-cultural learning within the health professions. The book concludes with recommendations for data collection and research initiatives. Unequal Treatment will be vitally important to health care policymakers, administrators, providers, educators, and students as well as advocates for people of color.

Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations

Download Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 030917452X
Total Pages : 56 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations by : Institute of Medicine

Download or read book Pharmacokinetics and Drug Interactions in the Elderly and Special Issues in Elderly African-American Populations written by Institute of Medicine and published by National Academies Press. This book was released on 1997-08-25 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reports in the popular press about the increasing longevity of Americans and the aging of the baby boom generation are constant reminders that the American population is becoming older. Consequently, an issue of growing medical, health policy, and social concern is the appropriate and rational use of medications by the elderly. Although becoming older does not necessarily correlate with increasing illness, aging is associated with anatomical and physiological changes that affect how medications are metabolized by the body. Furthermore, aging is often related to an increased frequency of chronic illness (often combined with multiple health problems) and an increased use of medications. Thus, a better understanding of the absorption, distribution, metabolism, and excretion of drugs; of the physiologic responses to those medications; as well as of the interactions among multiple medications is crucial for improving the health of older people.

P.C., M.D.

Download P.C., M.D. PDF Online Free

Author :
Publisher : Basic Books
ISBN 13 : 0465012345
Total Pages : 302 pages
Book Rating : 4.4/5 (65 download)

DOWNLOAD NOW!


Book Synopsis P.C., M.D. by : Sally Satel

Download or read book P.C., M.D. written by Sally Satel and published by Basic Books. This book was released on 2008-01-07 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on a wealth of information PC, M.D. documents for the first time what happens when the tenets of political correctness-including victimology, multiculturalism, rejection of fixed truths and individual autonomy-are allowed to enter the fortress of medicine.

Biopharmaceutics

Download Biopharmaceutics PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119678285
Total Pages : 324 pages
Book Rating : 4.1/5 (196 download)

DOWNLOAD NOW!


Book Synopsis Biopharmaceutics by : Hannah Batchelor

Download or read book Biopharmaceutics written by Hannah Batchelor and published by John Wiley & Sons. This book was released on 2021-12-20 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explore the latest research in biopharmaceutics from leading contributors in the field In Biopharmaceutics - From Fundamentals to Industrial Practice, distinguished Scientists from the UK's Academy of Pharmaceutical Sciences Biopharmaceutica Focus Group deliver a comprehensive examination of the tools used within the field of biopharmaceutics and their applications to drug development. This edited volume is an indispensable tool for anyone seeking to better understand the field of biopharmaceutics as it rapidly develops and evolves. Beginning with an expansive introduction to the basics of biopharmaceutics and the context that underpins the field, the included resources go on to discuss how biopharmaceutics are integrated into product development within the pharmaceutical industry. Explorations of how the regulatory aspects of biopharmaceutics function, as well as the impact of physiology and anatomy on the rate and extent of drug absorption, follow. Readers will find insightful discussions of physiologically based modeling as a valuable asset in the biopharmaceutics toolkit and how to apply the principles of the field to special populations. The book goes on to discuss: Thorough introductions to biopharmaceutics, basic pharmacokinetics, and biopharmaceutics measures Comprehensive explorations of solubility, permeability, and dissolution Practical discussions of the use of biopharmaceutics to inform candidate drug selection and optimization, as well as biopharmaceutics tools for rational formulation design In-depth examinations of biopharmaceutics classification systems and regulatory biopharmaceutics, as well as regulatory biopharmaceutics and the impact of anatomy and physiology Perfect for professionals working in the pharmaceutical and biopharmaceutical industries, Biopharmaceutics - From Fundamentals to Industrial Practice is an incisive and up-to-date resource on the practical, pharmaceutical applications of the field.

Ethnicity and Psychopharmacology

Download Ethnicity and Psychopharmacology PDF Online Free

Author :
Publisher : American Psychiatric Pub
ISBN 13 : 158562831X
Total Pages : 168 pages
Book Rating : 4.5/5 (856 download)

DOWNLOAD NOW!


Book Synopsis Ethnicity and Psychopharmacology by : Pedro Ruiz

Download or read book Ethnicity and Psychopharmacology written by Pedro Ruiz and published by American Psychiatric Pub. This book was released on 2008-11-01 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ethnicity and Psychopharmacology addresses the most relevant theoretical and clinical aspects of ethnopsychopharmacology, with the aim of advancing this growing field well into the twenty-first century. Detailed are the pharmacogenetic, pharmacokinetic, and pharmacodynamic mechanisms involved in differing responses to drug treatment among various ethnic groups living in the United States. Readers will learn an integrative approach in which ethnic and cultural diversity and biological diversity are taken into account and treatment is tailored to specific individual characteristics. Dr. Ruiz's extensive research experience and years of leadership in public psychiatry along with his distinguished panel of contributors combine to make this book an authoritative resource. Psychiatric practitioners, educators, and investigators, as well as other mental health professionals, primary care physicians and medical students, will gain a better understanding of treating patients from different cultures.

Alzheimer's Disease

Download Alzheimer's Disease PDF Online Free

Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1839162740
Total Pages : 695 pages
Book Rating : 4.8/5 (391 download)

DOWNLOAD NOW!


Book Synopsis Alzheimer's Disease by : Thimmaiah Govindaraju

Download or read book Alzheimer's Disease written by Thimmaiah Govindaraju and published by Royal Society of Chemistry. This book was released on 2022-01-04 with total page 695 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer’s disease is an increasingly common form of dementia and despite rising interest in discovery of novel treatments and investigation into aetiology, there are no currently approved treatments that directly tackle the causes of the condition. Due to its multifactorial pathogenesis, current treatments are directed against symptoms and even precise diagnosis remains difficult as the majority of cases are diagnosed symptomatically and usually confirmed only by autopsy. Alzheimer’s Disease: Recent Findings in Pathophysiology, Diagnostic and Therapeutic Modalities provides a comprehensive overview from aetiology and neurochemistry to diagnosis, evaluation and management of Alzheimer's disease, and latest therapeutic approaches. Intended to provide an introduction to all aspects of the disease and latest developments, this book is ideal for students, postgraduates and researchers in neurochemistry, neurological drug discovery and Alzheimer’s disease.

Advanced Drug Delivery Systems in the Management of Cancer

Download Advanced Drug Delivery Systems in the Management of Cancer PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 0323900798
Total Pages : 572 pages
Book Rating : 4.3/5 (239 download)

DOWNLOAD NOW!


Book Synopsis Advanced Drug Delivery Systems in the Management of Cancer by : Kamal Dua

Download or read book Advanced Drug Delivery Systems in the Management of Cancer written by Kamal Dua and published by Elsevier. This book was released on 2021-06-24 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Drug Delivery Systems in the Management of Cancer discusses recent developments in nanomedicine and nano-based drug delivery systems used in the treatment of cancers affecting the blood, lungs, brain, and kidneys. The research presented in this book includes international collaborations in the area of novel drug delivery for the treatment of cancer. Cancer therapy remains one of the greatest challenges in modern medicine, as successful treatment requires the elimination of malignant cells that are closely related to normal cells within the body. Advanced drug delivery systems are carriers for a wide range of pharmacotherapies used in many applications, including cancer treatment. The use of such carrier systems in cancer treatment is growing rapidly as they help overcome the limitations associated with conventional drug delivery systems. Some of the conventional limitations that these advanced drug delivery systems help overcome include nonspecific targeting, systemic toxicity, poor oral bioavailability, reduced efficacy, and low therapeutic index. This book begins with a brief introduction to cancer biology. This is followed by an overview of the current landscape in pharmacotherapy for the cancer management. The need for advanced drug delivery systems in oncology and cancer treatment is established, and the systems that can be used for several specific cancers are discussed. Several chapters of the book are devoted to discussing the latest technologies and advances in nanotechnology. These include practical solutions on how to design a more effective nanocarrier for the drugs used in cancer therapeutics. Each chapter is written with the goal of informing readers about the latest advancements in drug delivery system technologies while reinforcing understanding through various detailed tables, figures, and illustrations. Advanced Drug Delivery Systems in the Management of Cancer is a valuable resource for anyone working in the fields of cancer biology and drug delivery, whether in academia, research, or industry. The book will be especially useful for researchers in drug formulation and drug delivery as well as for biological and translational researchers working in the field of cancer. Presents an overview of the recent perspectives and challenges within the management and diagnosis of cancer Provides insights into how advanced drug delivery systems can effectively be used in the management of a wide range of cancers Includes up-to-date information on diagnostic methods and treatment strategies using controlled drug delivery systems

Revisiting Race in a Genomic Age

Download Revisiting Race in a Genomic Age PDF Online Free

Author :
Publisher : Rutgers University Press
ISBN 13 : 081354324X
Total Pages : 396 pages
Book Rating : 4.8/5 (135 download)

DOWNLOAD NOW!


Book Synopsis Revisiting Race in a Genomic Age by : Barbara A. Koenig

Download or read book Revisiting Race in a Genomic Age written by Barbara A. Koenig and published by Rutgers University Press. This book was released on 2008 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essays explore a range of topics that include drug development and the production of race-based therapeutics, the ways in which genetics could contribute to future health disparities, the social implications of ancestry mapping, and the impact of emerging race and genetics research on public policy and the media.

Applications of Pharmacokinetic Principles in Drug Development

Download Applications of Pharmacokinetic Principles in Drug Development PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9780306477669
Total Pages : 576 pages
Book Rating : 4.4/5 (776 download)

DOWNLOAD NOW!


Book Synopsis Applications of Pharmacokinetic Principles in Drug Development by : Rajesh Krishna

Download or read book Applications of Pharmacokinetic Principles in Drug Development written by Rajesh Krishna and published by Springer Science & Business Media. This book was released on 2004 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a collection of articles that representindividual and expert perspectives in both preclinical and clinicaldevelopment, including case studies on real-life examples ofsuccessful drugs that add value to the pharmacokinetic principleslearned and applied. Unlike existing books that focus onpharmacokinetic theory, the current book emphasizes application ofpharmacokinetic principles in new drug development.

Pharmaceutical Medicine

Download Pharmaceutical Medicine PDF Online Free

Author :
Publisher : OUP Oxford
ISBN 13 : 0191510394
Total Pages : 473 pages
Book Rating : 4.1/5 (915 download)

DOWNLOAD NOW!


Book Synopsis Pharmaceutical Medicine by : Adrian Kilcoyne

Download or read book Pharmaceutical Medicine written by Adrian Kilcoyne and published by OUP Oxford. This book was released on 2013-05-23 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: The breadth of the pharmaceutical medicine can be daunting, but this book is designed to navigate a path through the speciality. Providing a broad overview of all topics relevant to the discipline of pharmaceutical medicine, it gives you the facts fast, in a user-friendly format, without having to dive through page upon page of dense text. With 136 chapters spread across 8 sections, the text offers a thorough grounding in issues ranging from medicines regulation to clinical trial design and data management. This makes it a useful revision aid for exams as well as giving you a taster of areas of pharmaceutical medicine adjacent to your current role. For healthcare professionals already working in the field, this book offers a guiding hand in difficult situations as well as supplying rapid access to the latest recommendations and guidelines. Written by authors with experience in the industry and drug regulation, this comprehensive and authoritative guide provides a shoulder to lean on throughout your pharmaceutical career.

Inclusion

Download Inclusion PDF Online Free

Author :
Publisher : ReadHowYouWant.com
ISBN 13 : 1459606027
Total Pages : 430 pages
Book Rating : 4.4/5 (596 download)

DOWNLOAD NOW!


Book Synopsis Inclusion by : Steven Epstein

Download or read book Inclusion written by Steven Epstein and published by ReadHowYouWant.com. This book was released on 2010-10 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: With Inclusion, Steven Epstein argues that strategies to achieve diversity in medical research mask deeper problems, ones that might require a different approach and different solutions. Formal concern with this issue, Epstein shows, is a fairly recent phenomenon. Until the mid-1980s, scientists often studied groups of white, middle-aged men - and assumed that conclusions drawn from studying them would apply to the rest of the population. But struggles involving advocacy groups, experts, and Congress led to reforms that forced researchers to diversify the population from which they drew for clinical research. While the prominence of these inclusive practices has offered hope to traditionally underserved groups, Epstein argues that it has drawn attention away from the tremendous inequalities in health that are rooted not in biology but in society. This edition is in two volumes. The second volume ISBN is 9781458732194.

The Drug Development Paradigm in Oncology

Download The Drug Development Paradigm in Oncology PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309457971
Total Pages : 145 pages
Book Rating : 4.3/5 (94 download)

DOWNLOAD NOW!


Book Synopsis The Drug Development Paradigm in Oncology by : National Academies of Sciences, Engineering, and Medicine

Download or read book The Drug Development Paradigm in Oncology written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-02-12 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in cancer research have led to an improved understanding of the molecular mechanisms underpinning the development of cancer and how the immune system responds to cancer. This influx of research has led to an increasing number and variety of therapies in the drug development pipeline, including targeted therapies and associated biomarker tests that can select which patients are most likely to respond, and immunotherapies that harness the body's immune system to destroy cancer cells. Compared with standard chemotherapies, these new cancer therapies may demonstrate evidence of benefit and clearer distinctions between efficacy and toxicity at an earlier stage of development. However, there is a concern that the traditional processes for cancer drug development, evaluation, and regulatory approval could impede or delay the use of these promising cancer treatments in clinical practice. This has led to a number of effortsâ€"by patient advocates, the pharmaceutical industry, and the Food and Drug Administration (FDA)â€"to accelerate the review of promising new cancer therapies, especially for cancers that currently lack effective treatments. However, generating the necessary data to confirm safety and efficacy during expedited drug development programs can present a unique set of challenges and opportunities. To explore this new landscape in cancer drug development, the National Academies of Sciences, Engineering, and Medicine developed a workshop held in December 2016. This workshop convened cancer researchers, patient advocates, and representatives from industry, academia, and government to discuss challenges with traditional approaches to drug development, opportunities to improve the efficiency of drug development, and strategies to enhance the information available about a cancer therapy throughout its life cycle in order to improve its use in clinical practice. This publication summarizes the presentations and discussions from the workshop.

Pharmacogenomics

Download Pharmacogenomics PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527616306
Total Pages : 599 pages
Book Rating : 4.5/5 (276 download)

DOWNLOAD NOW!


Book Synopsis Pharmacogenomics by : Julio Licinio

Download or read book Pharmacogenomics written by Julio Licinio and published by John Wiley & Sons. This book was released on 2009-07-30 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work represents the first comprehensive publication in the innovative field of pharmacogenomics, a field which is set to revolutionize pharmaceutical research. In addition to renowned editors, the list of contributors is a "who-is-who" in the field. Broad coverage of all aspects of pharmacogenomics with a full presentation of applications to disease conditions is featured. Anyone involved in pharmaceutical research and drug development needs this book to keep up with this new and revolutionary approach

Marcus and Feldman's Osteoporosis

Download Marcus and Feldman's Osteoporosis PDF Online Free

Author :
Publisher : Academic Press
ISBN 13 : 0128130741
Total Pages : 1950 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!


Book Synopsis Marcus and Feldman's Osteoporosis by : David W. Dempster

Download or read book Marcus and Feldman's Osteoporosis written by David W. Dempster and published by Academic Press. This book was released on 2020-10-08 with total page 1950 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marcus and Feldman's Osteoporosis, Fifth Edition, is the most comprehensive, authoritative reference on this disease. Led by a new editorial team, this fifth edition offers critical information on reproductive and hormonal risk factors, new therapeutics, ethnicity, nutrition, therapeutics, management and economics, comprising a tremendous wealth of knowledge in a single source not found elsewhere. Written by renowned experts in the field, this two-volume reference is a must-have for biomedical researchers, research clinicians, fellows, academic and medical libraries, and any company involved in osteoporosis drug research and development. Summarizes the latest research in bone biology and translational applications in a range of new therapeutic agents, including essential updates on therapeutic uses of calcium, vitamin D, SERMS, bisphosphonates, parathyroid hormone, and new therapeutic agents Recognizes the critical importance of new signaling pathways for bone health, including Wnt, OPG and RANK, of interest to both researchers who study bone biology and clinicians who treat osteoporosis Offers new insights into osteoporosis associated with menopause, pre-menopause, chronic kidney disease, diabetes, HIV and other immune disorders

Migration, Ethnicity, Race, and Health in Multicultural Societies

Download Migration, Ethnicity, Race, and Health in Multicultural Societies PDF Online Free

Author :
Publisher : Oxford University Press
ISBN 13 : 0199667861
Total Pages : 388 pages
Book Rating : 4.1/5 (996 download)

DOWNLOAD NOW!


Book Synopsis Migration, Ethnicity, Race, and Health in Multicultural Societies by : Raj S. Bhopal

Download or read book Migration, Ethnicity, Race, and Health in Multicultural Societies written by Raj S. Bhopal and published by Oxford University Press. This book was released on 2014 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published: Ethnicity, race and health in multicultural societies, 2007.