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Analysis of Cancer Risks in Populations Near Nuclear Facilities

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309255716
Total Pages : 424 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Analysis of Cancer Risks in Populations Near Nuclear Facilities by : National Research Council

Download or read book Analysis of Cancer Risks in Populations Near Nuclear Facilities written by National Research Council and published by National Academies Press. This book was released on 2012-06-29 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late 1980s, the National Cancer Institute initiated an investigation of cancer risks in populations near 52 commercial nuclear power plants and 10 Department of Energy nuclear facilities (including research and nuclear weapons production facilities and one reprocessing plant) in the United States. The results of the NCI investigation were used a primary resource for communicating with the public about the cancer risks near the nuclear facilities. However, this study is now over 20 years old. The U.S. Nuclear Regulatory Commission requested that the National Academy of Sciences provide an updated assessment of cancer risks in populations near USNRC-licensed nuclear facilities that utilize or process uranium for the production of electricity. Analysis of Cancer Risks in Populations near Nuclear Facilities: Phase 1 focuses on identifying scientifically sound approaches for carrying out an assessment of cancer risks associated with living near a nuclear facility, judgments about the strengths and weaknesses of various statistical power, ability to assess potential confounding factors, possible biases, and required effort. The results from this Phase 1 study will be used to inform the design of cancer risk assessment, which will be carried out in Phase 2. This report is beneficial for the general public, communities near nuclear facilities, stakeholders, healthcare providers, policy makers, state and local officials, community leaders, and the media.

Applying Quantitative Bias Analysis to Epidemiologic Data

Author : Timothy L. Lash
Publisher : Springer Science & Business Media
ISBN 13 : 0387879595
Total Pages : 200 pages
Book Rating : 4.3/5 (878 download)

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Book Synopsis Applying Quantitative Bias Analysis to Epidemiologic Data by : Timothy L. Lash

Download or read book Applying Quantitative Bias Analysis to Epidemiologic Data written by Timothy L. Lash and published by Springer Science & Business Media. This book was released on 2011-04-14 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bias analysis quantifies the influence of systematic error on an epidemiology study’s estimate of association. The fundamental methods of bias analysis in epi- miology have been well described for decades, yet are seldom applied in published presentations of epidemiologic research. More recent advances in bias analysis, such as probabilistic bias analysis, appear even more rarely. We suspect that there are both supply-side and demand-side explanations for the scarcity of bias analysis. On the demand side, journal reviewers and editors seldom request that authors address systematic error aside from listing them as limitations of their particular study. This listing is often accompanied by explanations for why the limitations should not pose much concern. On the supply side, methods for bias analysis receive little attention in most epidemiology curriculums, are often scattered throughout textbooks or absent from them altogether, and cannot be implemented easily using standard statistical computing software. Our objective in this text is to reduce these supply-side barriers, with the hope that demand for quantitative bias analysis will follow.

Concepts of Epidemiology

Author : Raj S. Bhopal
Publisher : Oxford University Press
ISBN 13 : 0198739680
Total Pages : 481 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis Concepts of Epidemiology by : Raj S. Bhopal

Download or read book Concepts of Epidemiology written by Raj S. Bhopal and published by Oxford University Press. This book was released on 2016 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: First edition published in 2002. Second edition published in 2008.

Epidemiological Studies: A Practical Guide

Author : Alan J. Silman
Publisher : Oxford University Press
ISBN 13 : 0192546317
Total Pages : 305 pages
Book Rating : 4.1/5 (925 download)

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Book Synopsis Epidemiological Studies: A Practical Guide by : Alan J. Silman

Download or read book Epidemiological Studies: A Practical Guide written by Alan J. Silman and published by Oxford University Press. This book was released on 2018-10-18 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: To successfully conduct an epidemiological study, academic subject knowledge must be combined with careful consideration of the practical elements involved. From an academic perspective, insights into the basis of epidemiology, the concepts behind how we study diseases, and the challenges and limitations of the results that emerge are prioritised. However, the success of the academic analysis depends on how, when, and where the data used is collected. Epidemiological Studies: A Practical Guide focuses on the practical challenges of epidemiological data collection. Essential topics, such as how to choose the population to study, how to maximise participation and retention, and how to frame questions so that subjects provide the information required, are the core of the material presented. The book explains the skills needed to conduct a study where data is collected and presented accurately, and in appropriate formats. In addition to presenting a step-by-step guide to epidemiological investigations, the chapters in the book are accompanied by examples of how to phrase the letters and forms needed for each stage of conducting a study. Focusing on measurement, study designs, statistics, methodological issues, and key skills, the book provides a valuable background to epidemiological study. With detailed tables and figures, a clear chapter outline, and a straightforward index, the information presented is easily accessible and can quickly be applied to the reader's own work. Extensively revised, this new edition includes updates on case-crossover, Mendelian randomisation, and case-cohort. New chapters have been added to reflect the areas a student is now likely to encounter in an introductory epidemiological course, such as evidence synthesis, use of routine data, association or causation, feasibility, and pilot studies. Epidemiological Studies: A Practical Guide is ideal for students in epidemiology, public health, health research, and health services research. It is also highly relevant to post-graduate research students, and early stage clinical and non-clinical researchers.

Handbook of Life Course Health Development

Author : Neal Halfon
Publisher : Springer
ISBN 13 : 3319471430
Total Pages : 667 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Handbook of Life Course Health Development by : Neal Halfon

Download or read book Handbook of Life Course Health Development written by Neal Halfon and published by Springer. This book was released on 2017-11-20 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. This handbook synthesizes and analyzes the growing knowledge base on life course health development (LCHD) from the prenatal period through emerging adulthood, with implications for clinical practice and public health. It presents LCHD as an innovative field with a sound theoretical framework for understanding wellness and disease from a lifespan perspective, replacing previous medical, biopsychosocial, and early genomic models of health. Interdisciplinary chapters discuss major health concerns (diabetes, obesity), important less-studied conditions (hearing, kidney health), and large-scale issues (nutrition, adversity) from a lifespan viewpoint. In addition, chapters address methodological approaches and challenges by analyzing existing measures, studies, and surveys. The book concludes with the editors’ research agenda that proposes priorities for future LCHD research and its application to health care practice and health policy. Topics featured in the Handbook include: The prenatal period and its effect on child obesity and metabolic outcomes. Pregnancy complications and their effect on women’s cardiovascular health. A multi-level approach for obesity prevention in children. Application of the LCHD framework to autism spectrum disorder. Socioeconomic disadvantage and its influence on health development across the lifespan. The importance of nutrition to optimal health development across the lifespan. The Handbook of Life Course Health Development is a must-have resource for researchers, clinicians/professionals, and graduate students in developmental psychology/science; maternal and child health; social work; health economics; educational policy and politics; and medical law as well as many interrelated subdisciplines in psychology, medicine, public health, mental health, education, social welfare, economics, sociology, and law.

Foundations of Epidemiology

Author : Marit L. Bovbjerg
Publisher :
ISBN 13 : 9781955101035
Total Pages : 176 pages
Book Rating : 4.1/5 (1 download)

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Book Synopsis Foundations of Epidemiology by : Marit L. Bovbjerg

Download or read book Foundations of Epidemiology written by Marit L. Bovbjerg and published by . This book was released on 2020-10 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Foundations of Epidemiology is an open access, introductory epidemiology text intended for students and practitioners in public or allied health fields. It covers epidemiologic thinking, causality, incidence and prevalence, public health surveillance, epidemiologic study designs and why we care about which one is used, measures of association, random error and bias, confounding and effect modification, and screening. Concepts are illustrated with numerous examples drawn from contemporary and historical public health issues.

Epidemiology

Author : Mark Woodward
Publisher : CRC Press
ISBN 13 : 1482243202
Total Pages : 844 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Epidemiology by : Mark Woodward

Download or read book Epidemiology written by Mark Woodward and published by CRC Press. This book was released on 2013-12-19 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highly praised for its broad, practical coverage, the second edition of this popular text incorporated the major statistical models and issues relevant to epidemiological studies. Epidemiology: Study Design and Data Analysis, Third Edition continues to focus on the quantitative aspects of epidemiological research. Updated and expanded, this edition shows students how statistical principles and techniques can help solve epidemiological problems. New to the Third Edition New chapter on risk scores and clinical decision rules New chapter on computer-intensive methods, including the bootstrap, permutation tests, and missing value imputation New sections on binomial regression models, competing risk, information criteria, propensity scoring, and splines Many more exercises and examples using both Stata and SAS More than 60 new figures After introducing study design and reviewing all the standard methods, this self-contained book takes students through analytical methods for both general and specific epidemiological study designs, including cohort, case-control, and intervention studies. In addition to classical methods, it now covers modern methods that exploit the enormous power of contemporary computers. The book also addresses the problem of determining the appropriate size for a study, discusses statistical modeling in epidemiology, covers methods for comparing and summarizing the evidence from several studies, and explains how to use statistical models in risk forecasting and assessing new biomarkers. The author illustrates the techniques with numerous real-world examples and interprets results in a practical way. He also includes an extensive list of references for further reading along with exercises to reinforce understanding. Web Resource A wealth of supporting material can be downloaded from the book’s CRC Press web page, including: Real-life data sets used in the text SAS and Stata programs used for examples in the text SAS and Stata programs for special techniques covered Sample size spreadsheet

Epidemiologic Research

Author : David G. Kleinbaum
Publisher : John Wiley & Sons
ISBN 13 : 9780471289852
Total Pages : 552 pages
Book Rating : 4.2/5 (898 download)

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Book Synopsis Epidemiologic Research by : David G. Kleinbaum

Download or read book Epidemiologic Research written by David G. Kleinbaum and published by John Wiley & Sons. This book was released on 1991-01-16 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epidemiologic Research Principles and Quantitative Methods DavidG. Kleinbaum, Ph.D. Lawrence L. Kupper. Ph.D. Hal Morgenstern,Ph.D. Epidemiologic Research covers the principles and methodsof planning, analysis and interpretation of epidemiologic researchstudies. It supplies the applied researcher with the mostup-to-date methodological thought and practice. Specifically, thebook focuses on quantitative (including statistical) issues arisingfrom epidemiologic investigations, as well as on the questions ofstudy design, measurement and validity. EpidemiologicResearch emphasizes practical techniques, procedures andstrategies. It presents them through a unified approach whichfollows the chronology of issues that arise during theinvestigation of an epidemic. The book's viewpoint ismultidisciplinary and equally useful to the epidemiologicresearcher and to the biostatistician. Theory is supplemented bynumerous examples, exercises and applications. Full solutions aregiven to all exercises in a separate solutions manual. Importantfeatures * Thorough discussion of the methodology of epidemiologicresearch * Stress on validity and hence on reliability * Balanced approach, presenting the most important prevailingviewpoints * Three chapters with applications of mathematical modeling

Epidemiologic Studies of Veterans Exposed to Depleted Uranium

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309178568
Total Pages : 58 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Epidemiologic Studies of Veterans Exposed to Depleted Uranium by : Institute of Medicine

Download or read book Epidemiologic Studies of Veterans Exposed to Depleted Uranium written by Institute of Medicine and published by National Academies Press. This book was released on 2008-09-11 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt: Depleted uranium, a component of some weapons systems, has been in use by the U.S. military since the 1991 Gulf War. Military personnel have been exposed to depleted uranium as the result of friendly fire incidents, cleanup and salvage operations, and proximity to burning depleted uranium-containing tanks and ammunition. Under a Congressional mandate, the Department of Defense sought guidance from the Institute of Medicine in evaluating the feasibility and design of an epidemiologic study that would assess health outcomes of exposure to depleted uranium. The study committee examined several options to study health outcomes of depleted uranium exposure in military and veteran populations and concluded that it would be difficult to design a study to comprehensively assess depleted uranium-related health outcomes with currently available data. The committee further concluded that the option most likely to obtain useful information about depleted uranium-related health outcomes would be a prospective cohort study if future military operations involve exposure to depleted uranium. The book contains recommendations aimed at improving future epidemiologic studies and identifying current active-duty military personnel and veterans with potential DU exposure.

Modern Epidemiology

Author : Kenneth J. Rothman
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781755641
Total Pages : 776 pages
Book Rating : 4.7/5 (556 download)

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Book Synopsis Modern Epidemiology by : Kenneth J. Rothman

Download or read book Modern Epidemiology written by Kenneth J. Rothman and published by Lippincott Williams & Wilkins. This book was released on 2008 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thoroughly revised and updated Third Edition of the acclaimed Modern Epidemiology reflects both the conceptual development of this evolving science and the increasingly focal role that epidemiology plays in dealing with public health and medical problems. Coauthored by three leading epidemiologists, with sixteen additional contributors, this Third Edition is the most comprehensive and cohesive text on the principles and methods of epidemiologic research. The book covers a broad range of concepts and methods, such as basic measures of disease frequency and associations, study design, field methods, threats to validity, and assessing precision. It also covers advanced topics in data analysis such as Bayesian analysis, bias analysis, and hierarchical regression. Chapters examine specific areas of research such as disease surveillance, ecologic studies, social epidemiology, infectious disease epidemiology, genetic and molecular epidemiology, nutritional epidemiology, environmental epidemiology, reproductive epidemiology, and clinical epidemiology.

Critical Appraisal of Epidemiological Studies and Clinical Trials

Author : Mark Elwood
Publisher : OUP Oxford
ISBN 13 : 0191004944
Total Pages : 615 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis Critical Appraisal of Epidemiological Studies and Clinical Trials by : Mark Elwood

Download or read book Critical Appraisal of Epidemiological Studies and Clinical Trials written by Mark Elwood and published by OUP Oxford. This book was released on 2007-02-22 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a logical system of critical appraisal, to allow readers to evaluate studies and to carry out their own studies more effectively. This system emphasizes the central importance of cause and effect relationships. Its great strength is that it is applicable to a wide range of issues, and both to intervention trials and observational studies. This system unifies the often different approaches used in epidemiology, health services research, clinical trials, and evidence-based medicine, starting from a logical consideration of cause and effect. The author's approach to the issues of study design, selection of subjects, bias, confounding, and the place of statistical methods has been praised for its clarity and interest. Systematic reviews, meta-analysis, and the applications of this logic to evidence-based medicine, knowledge-based health care, and health practice and policy are discussed. Current and often controversial examples are used, including screening for prostate cancer, publication bias in psychiatry, public health issues in developing countries, and conflicts between observational studies and randomized trials. Statistical issues are explained clearly without complex mathematics, and the most useful methods are summarized in the appendix. The final chapters give six applications of the critical appraisal of major studies: randomized trials of medical treatment and prevention, a prospective and a retrospective cohort study, a small matched case-control study, and a large case-control study. In these chapters, sections of the original papers are reproduced and the original studies placed in context by a summary of current developments.

Epidemiology

Author : Mark Woodward
Publisher : CRC Press
ISBN 13 : 9781584880097
Total Pages : 728 pages
Book Rating : 4.8/5 (8 download)

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Book Synopsis Epidemiology by : Mark Woodward

Download or read book Epidemiology written by Mark Woodward and published by CRC Press. This book was released on 1999-05-25 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epidemiology is a subject of growing importance, as witnessed by its role in the description and prediction of the impact of new diseases such as AIDS and new-variant CJD. Epidemiology: Study Design and Data Analysis covers the whole spectrum of standard analytical techniques used in epidemiology, from descriptive techniques in report writing to model diagnostics from generalized linear models. The author discusses the advantages, disadvantages, and alternatives to case-control, cohort and intervention studies and details such crucial concepts as incidence, prevalence, confounding and interaction. Many exercises are provided, based on real epidemiological data sets collected from all over the world. The data sets are also available on an associated web site. Epidemiology: Study Design and Data Analysis will be an invaluable textbook for statistics and medical students studying epidemiology, and a standard reference for practicing epidemiologists.

Epidemiology

Author : K. Vuylsteek
Publisher : IOS Press
ISBN 13 : 9789051991505
Total Pages : 382 pages
Book Rating : 4.9/5 (915 download)

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Book Synopsis Epidemiology by : K. Vuylsteek

Download or read book Epidemiology written by K. Vuylsteek and published by IOS Press. This book was released on 1994 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epidemiology is the study of the distribution and determinants of health-related states or events in specified populations, and the application of this to the control of health.

Standardization of Epidemiological Studies of Host Susceptibility

Author : Janice S. Dorman
Publisher : Springer Science & Business Media
ISBN 13 : 0306448920
Total Pages : 302 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Standardization of Epidemiological Studies of Host Susceptibility by : Janice S. Dorman

Download or read book Standardization of Epidemiological Studies of Host Susceptibility written by Janice S. Dorman and published by Springer Science & Business Media. This book was released on 1994 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a NATO ARW held in Pittsburgh, Pennsylvania, June 23-27, 1992.

Clinical Epidemiology

Author : R. Brian Haynes
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451178794
Total Pages : 516 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis Clinical Epidemiology by : R. Brian Haynes

Download or read book Clinical Epidemiology written by R. Brian Haynes and published by Lippincott Williams & Wilkins. This book was released on 2012-03-29 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Third Edition of this popular text focuses on clinical-practice research methods. It is written by clinicians with experience in generating and answering researchable questions about real-world clinical practice and health care—the prevention, treatment, diagnosis, prognosis, and causes of diseases, the measurement of quality of life, and the effects of innovations in health services. The book has a problem-oriented and protocol-based approach and is written at an introductory level, emphasizing key principles and their applications. A bound-in CD-ROM contains the full text of the book to help the reader locate needed information.

Epidemiological Research Methods

Author : Donald R. McNeil
Publisher : John Wiley & Sons
ISBN 13 : 9780471961963
Total Pages : 320 pages
Book Rating : 4.9/5 (619 download)

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Book Synopsis Epidemiological Research Methods by : Donald R. McNeil

Download or read book Epidemiological Research Methods written by Donald R. McNeil and published by John Wiley & Sons. This book was released on 1996-08-06 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concepts of epidemiology, the science that uses statistical methods to investigate associations between risk factors and disease outcomes in human populations, are developed using examples involving real data from published studies. The relevant statistical methods are developed systematically to provide an integrated approach to observational and experimental studies. After covering basic measurement, study design, and study credibility issues, the author continues with basic statistical methods and techniques for adjusting risk estimates for confounders. Statistical models including logistic regression and the proportional hazards model for survival analysis are explained in detail in the following chapters, concluding with an explanation of the general methods for determining the sample size and power requirements for an epidemiological study. Taking advantage of the power, accessibility and user-friendliness of modern computer packages, the author uses a variety of interesting data sets and graphical displays to illustrate the methods. Epidemiological Research Methods will be of interest to students and research workers who need to learn and appreciate modern approaches to the subject. Without unnecessary emphasis on mathematics or theory, the book will enable the reader to gain a greater level of understanding of the underlying methods than is normally provided in books on epidemiology.

Epidemiology Matters

Author : Katherine M. Keyes
Publisher : Oxford University Press, USA
ISBN 13 : 0199331243
Total Pages : 257 pages
Book Rating : 4.1/5 (993 download)

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Book Synopsis Epidemiology Matters by : Katherine M. Keyes

Download or read book Epidemiology Matters written by Katherine M. Keyes and published by Oxford University Press, USA. This book was released on 2014 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epidemiology Matters offers a new approach to understanding and identifying the causes of disease -- and with it, how to prevent disease and improve human health. Utilizing visual explanations and examples, this text provides an accessible, step-by-step introduction to the fundamentals of epidemiologic study, from design to analysis. Across fourteen chapters, Epidemiology Matters teaches the individual competencies that underlie the conduct of an epidemiologic study: identifying populations; measuring exposures and health indicators; taking a sample; estimating associations between exposures and health indicators; assessing evidence for causes working together; assessing internal and external validity of results. With its consequentialist approach -- designing epidemiologic studies that aim to inform our understanding, and therefore improve public health -- Epidemiology Matters is an introductory text for the next generation of students in medicine and public health.