Enzyme Mixtures and Complex Biosynthesis

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Publisher : CRC Press
ISBN 13 : 1498712851
Total Pages : 137 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Enzyme Mixtures and Complex Biosynthesis by : Sanjoy K. Bhattacharya

Download or read book Enzyme Mixtures and Complex Biosynthesis written by Sanjoy K. Bhattacharya and published by CRC Press. This book was released on 2007-10-29 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, an ensemble of examples is provided to illustrate the diversity of approaches and applications to which the multi-enzyme catalysis is currently applied. Enzymes act in living beings as extremely complex, network mixtures that are supportive of all the biochemical transformations on which the life is based. In the biotechnological context, many of the enzymatic processes performed in vitro at both small and industrial scales lie on the enzymatic transformation of a single molecular species for the generation of a product and as catalyzed by a single enzyme. However, the number of technological applications for which cell-free enzyme mixtures are required is increasing and the science of how to combine individual reactions in complex processes is under speedy development. Obviously, any of the current in-progress multi-enzyme processes is fully mimicking the complexity of a living cell or cell community. However, the refined combination of selected enzymes and substrates is offering a new technological approach that is supporting the development of new or improved products in many fields such as food, leather and pharmaceutical industries. This book is unique and presents selective examples of each of these processes have been incorporated in this book by experts in their respective areas.

Complex Enzymes in Microbial Natural Product Biosynthesis, Part B: Polyketides, Aminocoumarins and Carbohydrates

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Author :
Publisher : Academic Press
ISBN 13 : 0080923364
Total Pages : 644 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Complex Enzymes in Microbial Natural Product Biosynthesis, Part B: Polyketides, Aminocoumarins and Carbohydrates by :

Download or read book Complex Enzymes in Microbial Natural Product Biosynthesis, Part B: Polyketides, Aminocoumarins and Carbohydrates written by and published by Academic Press. This book was released on 2009-04-11 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial natural products have been an important traditional source of valuable antibiotics and other drugs but interest in them waned in the 1990s when big pharma decided that their discovery was no longer cost-effective and concentrated instead on synthetic chemistry as a source of novel compounds, often with disappointing results. Moreover understanding the biosynthesis of complex natural products was frustratingly difficult. With the development of molecular genetic methods to isolate and manipulate the complex microbial enzymes that make natural products, unexpected chemistry has been revealed and interest in the compounds has again flowered. This two-volume treatment of the subject will showcase the most important chemical classes of complex natural products: the peptides, made by the assembly of short chains of amino acid subunits, and the polyketides, assembled from the joining of small carboxylic acids such as acetate and malonate. In both classes, variation in sub-unit structure, number and chemical modification leads to an almost infinite variety of final structures, accounting for the huge importance of the compounds in nature and medicine. Gathers tried and tested methods and techniques from top players in the field Provides an extremely useful reference for the experienced research scientist Covers biosynthesis of Polyketides, Tarpenoids, Aminocoumarins and Crabohydrates

Molecular Biology of the Cell

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Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Exocrine Pancreas

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Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041389
Total Pages : 66 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis The Exocrine Pancreas by : Stephen Pandol

Download or read book The Exocrine Pancreas written by Stephen Pandol and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 66 pages. Available in PDF, EPUB and Kindle. Book excerpt: The secretions of the exocrine pancreas provide for digestion of a meal into components that are then available for processing and absorption by the intestinal epithelium. Without the exocrine pancreas, malabsorption and malnutrition result. This chapter describes the cellular participants responsible for the secretion of digestive enzymes and fluid that in combination provide a pancreatic secretion that accomplishes the digestive functions of the gland. Key cellular participants, the acinar cell and the duct cell, are responsible for digestive enzyme and fluid secretion, respectively, of the exocrine pancreas. This chapter describes the neurohumoral pathways that mediate the pancreatic response to a meal as well as details of the cellular mechanisms that are necessary for the organ responses, including protein synthesis and transport and ion transports, and the regulation of these responses by intracellular signaling systems. Examples of pancreatic diseases resulting from dysfunction in cellular mechanisms provide emphasis of the importance of the normal physiologic mechanisms.

Medical Biochemistry

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Publisher : Academic Press
ISBN 13 : 0323916007
Total Pages : 910 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Medical Biochemistry by : Antonio Blanco

Download or read book Medical Biochemistry written by Antonio Blanco and published by Academic Press. This book was released on 2022-03-23 with total page 910 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of Medical Biochemistry is supported by more than 45 years of teaching experience, providing coverage of basic biochemical topics, including the structural, physical, and chemical properties of water, carbohydrates, lipids, proteins, and nucleic acids. In addition, the general aspects of thermodynamics, enzymes, bioenergetics, and metabolism are presented in straightforward and easy-to-comprehend language. This book ties these concepts into more complex aspects of biochemistry using a systems approach, dedicating chapters to the integral study of biological phenomena, including cell membrane structure and function, gene expression and regulation, protein synthesis and post-translational modifications, metabolism in specific organs and tissues, autophagy, cell receptors, signal transduction pathways, biochemical bases of endocrinology, immunity, vitamins and minerals, and hemostasis. The field of biochemistry is continuing to grow at a fast pace. This edition has been revised and expanded with all-new sections on the cell plasma membrane, the human microbiome, autophagy, noncoding, small and long RNAs, epigenetics, genetic diseases, virology and vaccines, cell signaling, and different modes of programmed cell death. The book has also been updated with full-color figures, new tables, chapter summaries, and further medical examples to improve learning and better illustrate the concepts described and their clinical significance. - Integrates basic biochemistry principles with molecular biology and molecular physiology - Illustrates basic biochemical concepts through medical and physiological examples - Utilizes a systems approach to understanding biological phenomena - Fully updated for recent studies and expanded to include clinically relevant examples and succinct chapter summaries

Beyond the Molecular Frontier

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Publisher : National Academies Press
ISBN 13 : 0309168392
Total Pages : 238 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Beyond the Molecular Frontier by : National Research Council

Download or read book Beyond the Molecular Frontier written by National Research Council and published by National Academies Press. This book was released on 2003-03-19 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemistry and chemical engineering have changed significantly in the last decade. They have broadened their scopeâ€"into biology, nanotechnology, materials science, computation, and advanced methods of process systems engineering and controlâ€"so much that the programs in most chemistry and chemical engineering departments now barely resemble the classical notion of chemistry. Beyond the Molecular Frontier brings together research, discovery, and invention across the entire spectrum of the chemical sciencesâ€"from fundamental, molecular-level chemistry to large-scale chemical processing technology. This reflects the way the field has evolved, the synergy at universities between research and education in chemistry and chemical engineering, and the way chemists and chemical engineers work together in industry. The astonishing developments in science and engineering during the 20th century have made it possible to dream of new goals that might previously have been considered unthinkable. This book identifies the key opportunities and challenges for the chemical sciences, from basic research to societal needs and from terrorism defense to environmental protection, and it looks at the ways in which chemists and chemical engineers can work together to contribute to an improved future.

The Handbook of Microbial Bioresources

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Author :
Publisher : CABI
ISBN 13 : 178064521X
Total Pages : 1058 pages
Book Rating : 4.7/5 (86 download)

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Book Synopsis The Handbook of Microbial Bioresources by : Vijai Kumar Gupta

Download or read book The Handbook of Microbial Bioresources written by Vijai Kumar Gupta and published by CABI. This book was released on 2016-06-27 with total page 1058 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial technology plays an integral role in the biotechnology, bioengineering, biomedicine/biopharmaceuticals and agriculture sector. This book provides a detailed compendium of the methods, biotechnological routes, and processes used to investigate different aspects of microbial resources and applications. It covers the fundamental and applied aspects of microorganisms in the health, industry, agriculture and environmental sectors, reviewing subjects as varied and topical as pest control, health and industrial developments and animal feed.

The Coronin Family of Proteins

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Publisher : Springer Science & Business Media
ISBN 13 : 0387095950
Total Pages : 152 pages
Book Rating : 4.3/5 (87 download)

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Book Synopsis The Coronin Family of Proteins by : Christoph S. Clemen

Download or read book The Coronin Family of Proteins written by Christoph S. Clemen and published by Springer Science & Business Media. This book was released on 2008-10-17 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: The coronins, first described in Dictyostelium discoideum in 1991, have been detected in all eukaryotes except plants. They belong to the superfamily of WD40-repeat proteins and represent a large family of proteins, which are often involved in cytoskeletal functions. Phylogenetic studies clearly distinguish 12 subfamilies of which six exclusively occur in vertebrates. In the present book we have made a sincere attempt to provide a comprehensive overview on all aspects of coronin proteins including history, structure, subcellular localization and function in different organisms. In addition, we also included a general overview on the WD40 family of proteins and the structurally related Kelch family. The book should be of interest for scientists outside the field, but is more importantly intended as a fast and competent guide for newcomers as well as doctoral and postdoctoral scientists to coronin research in all its facets.

Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites

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Publisher : Springer
ISBN 13 : 1493911910
Total Pages : 357 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites by : Juan-Francisco Martín

Download or read book Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites written by Juan-Francisco Martín and published by Springer. This book was released on 2014-09-09 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume describes the more relevant secondary metabolites of different fungi with current information on their biosynthesis and molecular genetics. Bolstered with color illustrations and photographs, the book describes the possible application of molecular genetics to directed strain improvement in great detail. The needs for future developments in this field are also discussed at length Written by authorities in the field, Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites provides a cutting-edge perspective on fungal secondary metabolism and underlying genetics and is a valuable resource for scientists, researchers, and educators in the field of fungal biology.

Micro-algae: Next-generation Feedstock for Biorefineries

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Author :
Publisher : Springer Nature
ISBN 13 : 9811906807
Total Pages : 239 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis Micro-algae: Next-generation Feedstock for Biorefineries by : Pradeep Verma

Download or read book Micro-algae: Next-generation Feedstock for Biorefineries written by Pradeep Verma and published by Springer Nature. This book was released on 2022-07-26 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: The edited book covers all potential products from microalgal-based biorefinery having the focus on contemporary technologies and future outlook. Along with the focus on microalgal biorefinery products, the book also focuses on biotechnological advances via the utilization of modern molecular biology, system biology, synthetic biology, or metabolic engineering approach in microalgal biorefinery. The development of any technologies has a direct effect on the human being and the environment, therefore, the socio-economic, techno-economic, and environmental impact of the microalgae-based biorefineries will also be included in the book. In microalgal biomass-based biorefinery different biofuel- biodiesel, bioethanol, bio-hydrogen, and value-added compounds such as carotenoids, fatty acids, and protein can be produced simultaneously. Understanding the technical advances to develop an integrated biorefinery approach with the motive of designing a consolidated self-sustainable microalga-based biorefinery. This book is equally beneficial for researchers and engineers in biomass-based biorefineries or the bachelors, master, or young budding graduate students as a textbook.

Tropomyosin

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Publisher : Springer Science & Business Media
ISBN 13 : 0387857664
Total Pages : 323 pages
Book Rating : 4.3/5 (878 download)

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Book Synopsis Tropomyosin by : Peter Gunning

Download or read book Tropomyosin written by Peter Gunning and published by Springer Science & Business Media. This book was released on 2009-09-30 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: A recent review of one of my grant applications commented on the ‘rediscovery of tropomyosin’. I was tempted to write back in my rebuttal to the reviewer that I didn’t realise it had been lost. Uncharacteristic maturity prevailed and I resisted the temptation, but I was struck by the underlying observation that research on the str- ture and function of tropomyosin has been somewhat invisible, particularly in terms of the cytoskeleton isoforms. So, how can it be that one of the two major components of the actin filament has been so thoroughly overlooked? I suspect that the answer is disappointingly pedestrian. Whereas the biochemistry of the 1980s revealed the potential of tropomyosin isoforms to diversify the function of actin filaments, the subsequent disenchantment with isoform biology in general in the 1990s inhibited growth of this field. With the development of more sophisticated experimental - proaches we are now seeing a growing realisation of the importance of tropomyosin in regulating actin filaments beyond its pivotal role in muscle contraction. The opportunity to edit this book came at a time when we had written several reviews on different aspects of tropomyosin function and I had just finished the background reading for a comprehensive review of tropomyosin biology. I realised that the field was simply beyond the capacity of any one person to do the field j- tice.

Organizational Biosynthesis

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Publisher : Elsevier
ISBN 13 : 0323145582
Total Pages : 572 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Organizational Biosynthesis by : Henry Vogel

Download or read book Organizational Biosynthesis written by Henry Vogel and published by Elsevier. This book was released on 2012-12-02 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organizational Biosynthesis focuses on the organized biosynthesis of the bacterial chromosome and examines the fundamental aspects of this process. This book discusses the basic particles of biology, which are explored in terms of organizational biosynthetic events at the molecular level. Organized into 10 parts encompassing 45 chapters, this book starts with an overview of how cellular components recognize, coordinate, and interact with each other during cellular division and genetic recombination. This text then examines the biochemical experiments with bacteria, which strongly suggest the participation of a particulate fraction. Other chapters consider the molecular basis for the physical continuity of the chromosome. This book discusses as well the result of the experiments for bacteria, which shows that DNA replication can proceed only after both template strands of the replicating molecule attach to the cell. The final chapter deals with protein biosynthesis system in mitochondria. This book is a valuable resource for biologists and biochemists.

Radical SAM Enzymes

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Publisher : Academic Press
ISBN 13 : 9780128127940
Total Pages : 0 pages
Book Rating : 4.1/5 (279 download)

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Book Synopsis Radical SAM Enzymes by :

Download or read book Radical SAM Enzymes written by and published by Academic Press. This book was released on 2018-08-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radical SAM Enzymes, Volume 606, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on the Characterization of the glycyl radical enzyme choline trimethylamine-lyase and its radical S-adenosylmethionine activating enzyme, Diphathimide biosynthesis, Radical SAM glycyl radical activating enzymes, Radical SAM enzyme BioB in the biosynthesis of biotin, Biogenesis of the PQQ cofactor, Role of MoaAC in the biogenesis of the molybdenum cofactor, Biosynthesis of the nitrogenase cofactor, Bioinformatics of the radical SAM superfamily, The involvement of SAM radical enzymes in the biosynthesis of methanogenic coenzymes, methanopterin and coenzyme F420, and more.

Animal Cell Technology

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Author :
Publisher : Taylor & Francis
ISBN 13 : 113409972X
Total Pages : 565 pages
Book Rating : 4.1/5 (34 download)

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Book Synopsis Animal Cell Technology by : Leda Castilho

Download or read book Animal Cell Technology written by Leda Castilho and published by Taylor & Francis. This book was released on 2008-03-01 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Cell Technology: from Biopharmaceuticals to Gene Therapy provides a comprehensive insight into biological and engineering concepts related to mammalian and insect cell technology, as well as an overview of the applications of animal cell technology. Part 1 of the book covers the Fundamentals upon which this technology is based and covers the science underpinning the technology. Part 2 covers the Applications from the production of therapeutic proteins to gene therapy. The authors of the chapters are internationally-recognized in the field of animal cell culture research and have extensive experience in the areas covered in their respective chapters.

The Science and Applications of Synthetic and Systems Biology

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Publisher : National Academies Press
ISBN 13 : 0309219396
Total Pages : 570 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis The Science and Applications of Synthetic and Systems Biology by : Institute of Medicine

Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

The Organization of Cell Metabolism

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1468453114
Total Pages : 374 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis The Organization of Cell Metabolism by : G. Rickey Welch

Download or read book The Organization of Cell Metabolism written by G. Rickey Welch and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chemical and Biological Synthesis

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 178801507X
Total Pages : 317 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Chemical and Biological Synthesis by : Nick J Westwood

Download or read book Chemical and Biological Synthesis written by Nick J Westwood and published by Royal Society of Chemistry. This book was released on 2018-08-16 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic chemistry plays a central role in many areas of chemical biology; utilising recent case studies, the goal of Chemical and Biological Synthesis is to highlight the full impact that the preparation of novel reagents can have in chemical biology. Covering the synthetic approaches that can be applied across the whole field of chemical biology, this book provides synthetic chemists with the broader context to which their work contributes and the biological questions that can be addressed through it. An ideal guide for postgraduate students and researchers in synthetic organic chemistry and chemical biology, Chemical and Biological Synthesis introduces synthetic techniques and methods to those who wish to incorporate synthesis for the first time in their biology-focused research programmes.