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Endothelial Injury In Cardiac Transplantation
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Book Synopsis Cardiac Allograft Rejection by : G. William Dec
Download or read book Cardiac Allograft Rejection written by G. William Dec and published by Springer Science & Business Media. This book was released on 2001-09-30 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heart transplantation remains one of the major scientific achievements of twentieth century medicine. During the past four decades, it has evolved from an unproven experimental surgical technique to the most effective form of therapy for refractory end-stage heart disease. It has captured the public's imagination and expanded our understanding of fundamental immunologic mechanisms that are responsible for cellular and humorally-mediated immunity. Despite its successes, many clinical and scientific problems remain. One or more bouts of acute cellular or humoral (vascular) rejection will occur in over 75% of transplant recipients despite current immunosuppressive strategies. Further, rejection directly results in approximately 20% of post-transplant deaths and is believed to play a major role in the development of late allograft dysfunction and coronary vasculopathy. This book by international experts in the fields of transplantation medicine, immunobiology and cardiac imaging provides the reader with an up-to-date, consise summary of the latest developments in the diagnosis and treatment of acute cardiac rejection. It is axiomatic that a more complete understanding of the pathogenic processes involved in rejection will ultimately lead to its prevention. This volume will be useful to transplant cardiologists, cardiovascular surgeons, cardiac pathologists and transplant scientists who seek to prolong the lifespan and improve the quality of life of their transplant recipients.
Book Synopsis Interventional and Surgical Cardiovascular Pathology by : Frederick J. Schoen
Download or read book Interventional and Surgical Cardiovascular Pathology written by Frederick J. Schoen and published by . This book was released on 1989 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides clinicians with pathological descriptions and data serving to facilitate patient selection, optimal surgical procedures, and postoperative management. Includes anticipation and recognition of complications for each major disease area in which mechanical or other non-pharmacological therapy is available.
Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References
Book Synopsis Endothelium and Cardiovascular Diseases by : Protasio L. Da Luz
Download or read book Endothelium and Cardiovascular Diseases written by Protasio L. Da Luz and published by Academic Press. This book was released on 2018-02-03 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes provides an in-depth examination of the role of endothelium and endothelial dysfunction in normal vascular function, and in a broad spectrum of clinical syndromes, from atherosclerosis, to cognitive disturbances and eclampsia. The endothelium is a major participant in the pathophysiology of diseases, such as atherosclerosis, diabetes and hypertension, and these entities are responsible for the largest part of cardiovascular mortality and morbidly. Over the last decade major new discoveries and concepts involving the endothelium have come to light. This important reference collects this data in an easy to reference resource. Written by known experts, and covering all aspects of endothelial function in health and disease, this reference represents an assembly of recent knowledge that is essential to both basic investigators and clinicians. - Provides a complete overview of endothelial function in health and diseases, along with an assessment of new information - Includes coverage of groundbreaking areas, including the artificial LDL particle, the development of a new anti-erectile dysfunction agent, a vaccine for atherosclerosis, coronary calcification associated with red wine, and the interplay of endoplasmic reticulum/oxidative stress - Explores the genetic features of endothelium and the interaction between basic knowledge and clinical syndromes
Book Synopsis Pediatric Heart Transplantation by :
Download or read book Pediatric Heart Transplantation written by and published by . This book was released on 2019-04-03 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Pediatric Heart Transplantation
Book Synopsis Endothelial Dysfunction by : Helena Lenasi
Download or read book Endothelial Dysfunction written by Helena Lenasi and published by BoD – Books on Demand. This book was released on 2018-10-24 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium enables communication between blood and tissues and is actively involved in cardiovascular homeostasis. Endothelial dysfunction has been recognized as an early step in the development of cardiovascular diseases: respectively, endothelium represents a potential therapeutic niche with multiple targets. The purpose of the book is to point out some recent findings of endothelial physiology and pathophysiology emphasizing various aspects of endothelial dysfunction connected to the body's internal and external environment. While basic features of the endothelium are presented in an introductory chapter, the authors of the following 17 chapters have provided extensive insight into some selected topics of endothelial (dys)function. The book would hopefully be useful for anyone interested in recapitulating endothelial (patho)physiology and expanding knowledge of molecular mechanisms involved in endothelial dysfunction, relevant also for further clinical investigations.
Book Synopsis Contemporary Heart Transplantation by : Linda Bogar
Download or read book Contemporary Heart Transplantation written by Linda Bogar and published by Springer. This book was released on 2020-09-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work provides a one-of- a-kind volume that includes all aspects of heart transplantation from its historic beginning to its current day standards which now make the procedure a long-term treatment option for heart failure patients. The subjects covered include technical aspects of the procurement and implant procedures, as well as the medical nuances of pre-operative preparation and post-transplant immunosuppression management; the current day multi-disciplinary make up of the transplant team along with information on the keys to building and running a successful transplant program; regulatory standards and listing policies and the impact of the growing mechanical circulatory support technologies on the transplant field; and emerging technologies and future possibilities. All chapters are written by experts in the field and include the most up-to-date peer reviewed studies and clinical guidelines. This book gives an ever-changing reference that will become the text of choice for those beginning or continuing their transplant careers.
Book Synopsis Pediatric Hypertension by : Joseph Flynn
Download or read book Pediatric Hypertension written by Joseph Flynn and published by Springer Science & Business Media. This book was released on 2013-06-26 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of pediatric hypertension has undergone important changes in the time since the second edition of Pediatric Hypertension published. Much new information on hypertension in the young has become available. Previous chapters have been fully revised and new chapters have been added to cover important topics of recent interest such as consensus recommendations, the prevalence of hypertension in the young due to the obesity epidemic, studies of antihypertensive agents, and ambulatory blood pressure monitoring. Pediatric Hypertension, Third Edition is a comprehensive volume featuring 38 chapters covering the breadth of the current knowledge. It is divided into four sections: Regulation of Blood Pressure in Children; Assessment of Blood Pressure in Children: Measurement, Normative Data, Epidemiology; and Hypertension in Children: Predictors, Risk Factors, and Special Populations; Evaluation and Management of Pediatric Hypertension. Filled with the most up-to-date information, Pediatric Hypertension, Third Edition is an invaluable resource for clinicians and researchers interested in childhood hypertension.
Book Synopsis Cardiac Transplantation by : Susan Moffatt-Bruce
Download or read book Cardiac Transplantation written by Susan Moffatt-Bruce and published by BoD – Books on Demand. This book was released on 2012-02-10 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are truly in an era of change not only in terms of technology but in the type of patient we are caring for. That is why I feel this book is exciting in that it presents the team approach to the transplant patient. I am confident that the pioneers of cardiac transplantation would be pleased with our response to challenges in healthcare today and be pleased with the final product.
Book Synopsis Principles and Practice of Transplant Infectious Diseases by : Amar Safdar
Download or read book Principles and Practice of Transplant Infectious Diseases written by Amar Safdar and published by Springer. This book was released on 2019-06-13 with total page 1150 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive volume provides a platform from which both major and minor infectious diseases related issues are addressed in-depth among this highly susceptible population. The book begins with an overview of infections in various modalities. This is followed by chapters on clinical disorders, etiologic agents, therapeutics, and infection prevention. Chapters include easy-to-follow figures and tables, radiologic images, and pictorial demonstrations of various disease states to familiarize and reacquaint the transplant clinicians and surgeons in practice and training, and those belonging to subspecialties providing supportive care for these patients. Discussions to enumerate the noninfectious causes that mimic infectious diseases; clinical relevance and effective utility of existing and emerging diagnostic tools are presented throughout the book. Authored by leaders in their fields, this book is the go-to reference for management of patients undergoing hematopoietic and solid organ transplantation.
Book Synopsis Cardiac Transplantation by : Niloo M. Edwards
Download or read book Cardiac Transplantation written by Niloo M. Edwards and published by Springer Science & Business Media. This book was released on 2004-02-26 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading physicians summarize in this easy-to-use and eminently practical handbook the day-to-day management of transplant donors and recipients at Columbia-Presbyterian Medical Center. Topics covered range from surgical techniques, pathology, and immunosuppression, to posttransplant management, pediatric heart transplantation, surgical alternatives, and mechanical circulatory assistance as a bridge to transplantation. The authors also discuss congenital transplant techniques, state-of-the-art perioperative management techniques and protocols, and UNOS regulation and nurse coordination.
Book Synopsis Antibodies to Endothelial Cells and Vascular Damage by : Ricard Cervera
Download or read book Antibodies to Endothelial Cells and Vascular Damage written by Ricard Cervera and published by CRC Press. This book was released on 1993-11-24 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the original description of antibodies to endothelial cells in the early 1970s, and with the advent of sensitive and reproducible techniques for their detection, the scope for investigating the vascular damage of immunological disorders has widened considerably. In this book, leading world scientists have contributed chapters presenting broad coverage of basic science and clinical implications of immunological interactions of antibodies to endothelial cells. The book takes a multidisciplinary approach that will appeal to immunologists, rheumatologists, internists, and others interested in the subject.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Congestive Heart Failure and Cardiac Transplantation by : Daniel J. Garry
Download or read book Congestive Heart Failure and Cardiac Transplantation written by Daniel J. Garry and published by Springer. This book was released on 2017-06-01 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive overview of heart failure and cardiac transplantation and integrates scientific and clinical information about the physiology, pathophysiology, diagnosis, and treatment of this disorder. Organized into five parts, it reviews the history and basic mechanisms of heart failure; etiology of heart failure; heart failure disease progression; advanced therapies for heart failure; and cardiac transplantation. The book presents basic concepts in the physiology, molecular biology, pathology, and epidemiology of the normal and failing heart; known causes of heart failure, such as right heart failure, valvular cardiomyopathy, molecular mechanisms of sarcomeric cardiomyopathies, and neuromuscular cardiomyopathy; cardiorenal syndrome; neurohormonal activation; cardiac resynchronization, ventricular assist devices; regenerative mechanisms; orthotopic heart transplantation; early and late management of the post-transplant patient; heart transplantation and antibody-mediated rejections; heart-lung transplantation; and cardiac xenotransplantation. Featuring contributions from leaders in the fields of heart failure, cardiac transplantation, cardiac pathology, and cardiovascular molecular research, Congestive Heart Failure and Cardiac Transplantation is a valuable compendium for cardiologists, cardiothoracic surgeons, researchers, trainees, and students.
Book Synopsis A Practical Approach to Cardiac Anesthesia by : Frederick A. Hensley
Download or read book A Practical Approach to Cardiac Anesthesia written by Frederick A. Hensley and published by Lippincott Williams & Wilkins. This book was released on 2008 with total page 826 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most widely used clinical reference in cardiac anesthesia, this large handbook provides complete information on drugs, monitoring, cardiopulmonary bypass, circulatory support, and anesthetic management of specific cardiac disorders. It incorporates clinically relevant basic science into a practical "what-to-do" approach and is written in an easy-to-read outline format. This edition has a new chapter on surgical ventricular restoration, LV aneurysm, and CHF-related surgical procedures. Chapters provide increased coverage of postoperative atrial fibrillation prevention and treatment, drugs in perioperative risk reduction, and the role of inhalational anesthetics in organ protection via anesthetic preconditioning. This edition also has a revamped art program.
Book Synopsis Immunobiology of Organ Transplantation by : David S. Wilkes
Download or read book Immunobiology of Organ Transplantation written by David S. Wilkes and published by Springer Science & Business Media. This book was released on 2004-06-24 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently, individuals interested in seeking an in-depth discussion of transplantation immunology must seek individual articles published in several journals, or extrapolate information from various non-transplant immunology textbooks. The purpose of this text is to provide the reader with a single source of information for the basic science of immunobiology of organ transplantation. It is unique that it focuses on immunobiology from the basic research side, with an emphasis on the cellular and molecular levels. The readers will be physicians, scientists, and graduate students interested and engaged in the study of immunology as it relates to allo- and xenotransplantation. This book is designed to be the reference standard for the immunobiology of transplantation.
Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
