Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Antibodies To Endothelial Cells And Vascular Damage
Download Antibodies To Endothelial Cells And Vascular Damage full books in PDF, epub, and Kindle. Read online Antibodies To Endothelial Cells And Vascular Damage ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Antibodies to Endothelial Cells and Vascular Damage by : Ricard Cervera
Download or read book Antibodies to Endothelial Cells and Vascular Damage written by Ricard Cervera and published by CRC Press. This book was released on 1993-11-24 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the original description of antibodies to endothelial cells in the early 1970s, and with the advent of sensitive and reproducible techniques for their detection, the scope for investigating the vascular damage of immunological disorders has widened considerably. In this book, leading world scientists have contributed chapters presenting broad coverage of basic science and clinical implications of immunological interactions of antibodies to endothelial cells. The book takes a multidisciplinary approach that will appeal to immunologists, rheumatologists, internists, and others interested in the subject.
Book Synopsis Vascular Health: The Endothelial Perspective in Regulation of Inflammation and Injury by : Shampa Chatterjee
Download or read book Vascular Health: The Endothelial Perspective in Regulation of Inflammation and Injury written by Shampa Chatterjee and published by Frontiers Media SA. This book was released on 2021-11-01 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Endothelial Dysfunction During Inflammation and Alloimmunity by : Olaf Penack
Download or read book Endothelial Dysfunction During Inflammation and Alloimmunity written by Olaf Penack and published by Frontiers Media SA. This book was released on 2019-04-09 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endothelial cells form the inner lining of blood and lymphatic vessels and they have frequent interactions with immune cells as well as foreign agents. Endothelial function is crucially involved in physiologic immunity at different stages including recruitment of leukocytes, angiogenesis and tissue repair. Endothelial dysfunction is a not well-defined term, it is widely used to describe the non-physiologic activity of endothelial cells. It has been suggested that endothelial dysfunction plays a role in a variety of human diseases, such as arteriosclerosis, cancer, autoimmunity and sepsis. More recently, a role of lymphatic endothelial cells as well as vascular endothelial cells in the pathophysiology of inflammation and allo-immune reactions has been suggested. Development of novel therapeutic approaches to normalize endothelial dysfunction is currently an unmet medical need. Until now, the cellular and molecular mechanisms of mutual influences between endothelial dysfunction and human diseases remain largely unexplored, constituting a frontier hindering the development of new therapies. This Research Topic aims to build a forum for a wide range of scientific studies in the fields of endothelial dysfunction during inflammatory diseases and transplantation.
Book Synopsis Autoantibodies by : Yehuda Shoenfeld
Download or read book Autoantibodies written by Yehuda Shoenfeld and published by Newnes. This book was released on 2013-11-26 with total page 916 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autoimmune diseases are characterized by the occurrence of antibodies reacting with self-constituents of the body. The fully updated third edition of Autoantibodies is an in-depth review of the main autoantibodies identified up to now, with particular emphasis on those that display a diagnostic or prognostic clinical value. The new edition covers recent scientific advances, diagnostic techniques, and therapeutic technologies. Each chapter is focused on a single family of autoantibodies. This important reference contains historical notes, definitions, origins and sources of antigens recognized genetic associations, mediated pathogenic mechanisms, methods of detection, as well as clinical utility (disease prevalence and association, diagnostic value, sensitivity and specificity, prognostic value). This is an ideal reference for anyone involved in the field of autoimmune diseases. Presents all known, important autoantibodies in a single source, focusing on the antibodies needed for autoimmune disorder diagnosis Includes clinical applications for each autoantibody along with general information Organized by disease and disorder type, by autoantibody family, and completely cross-referenced
Book Synopsis Encyclopedia of Medical Immunology by : Ian R. Mackay
Download or read book Encyclopedia of Medical Immunology written by Ian R. Mackay and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering a broad appeal to microbiologists, immunologists, and infectious disease specialists, this four volume encyclopedia covers all autoimmune, tropical, and infectious diseases. Emphasis will also be placed on genetics, physiology, metabolism, pathogenesis and applied microbiology. Under the leadership of some of the most world renowned names in the field, the encyclopedia will bring together an outstanding collection of contributions by top scientists in a variety of fields. Volumes 1-3: Diseases will be divided by the 11 main sections of the body, namely Integumentary, Skeletal, Respiratory, Digestive, Urinary, and Reproductive. For some of the autoimmune disease, more then one system will be involved but the delineation serves to broadly break down the diseases into systems. Volume 4 will cover the vaccines for said diseases and future prospects will be offered by leaders in industry and academia. Volume 4 will also be broken down into all the body systems, as in the other two volumes. For each vaccine, for each disease, and in each system the following will be included: • A list of the vaccines currently available along with a list of the companies that manufacture them • Molecular Immunology of the Vaccine • Type of Immunity involved in protection • Mode of Vaccination for each vaccine; repeated boosters and length of immunological memory • Commercial production of vaccines • Storage of vaccines • Standardization and Control of Vaccines • WHO programs and World-Wide Disease Eradication Programs based upon Vaccines.
Book Synopsis Endothelial Signaling in Vascular Dysfunction and Disease by : Shampa Chatterjee
Download or read book Endothelial Signaling in Vascular Dysfunction and Disease written by Shampa Chatterjee and published by Academic Press. This book was released on 2021-01-20 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endothelial Signaling in Vascular Dysfunction and Disease: From Bench to Bedside provides a detailed understanding of the endothelium, its activation and their link to some common clinical disorders. In addition, the book covers earlier discoveries, including those from the last and 19th centuries. It is split into five sections that cover the vascular tree as an integrative structure, the endothelium in inflammation, endothelial signaling, activation and toxicity with chemotherapy, radiation induced endothelial dysfunction and vascular disease, and therapies in combating vascular diseases. Each section is discussed with a translational approach in order to make the content truly applicable. This book is a valuable source for basic researchers, clinicians in the fields of Oncology, Cardiovascular Medicine and Radiology, and members of the biomedical field who are conducting studies related to the endothelium and vascular disease. Discusses the most relevant discoveries in endothelial biology and their link to manifestations of clinical disease Presents history and diagrams in each section to highlight the original biological discovery and its link of clinical manifestations of vascular disease Includes recent findings on the relationship between endothelial signaling, chemotherapy and radiation induced endothelial dysfunction
Book Synopsis Endothelial Cell Biology in Health and Disease by : M. Simionescu
Download or read book Endothelial Cell Biology in Health and Disease written by M. Simionescu and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although blood capillaries were first observed through a flea-lens microscope by Malpighi in 1661,200 more years elapsed before the cellular nature of the vessel wall was conclusively demonstrated. Beginning with the middle of the 19th cen tury, our knowledge of the histological organization of blood vessels has steadily increased. However, the endothelium, which for a long time was considered to be just an inert barrier lining, had been barely explored until three decades ago. Since then, there has been an upsurge of interest in the fine structure and function of endothelial cells. Intense in vivo and in vitro investigations have revealed that the endothelial cell is a key element in a wide variety of normal activities and diseases. A large number of investigators and laboratories have been attracted to endothelial cell research, thus supporting the expansion of the continuously grow ing and diversifying field of endotheliology. The number of articles published annually on this subject has increased from a few score at the beginning of the 1970s to more than a thousand in recent years, and an increasing number of journals, books, societies, and symposia focused primarily on the vascular en dothelium have marked the last decade.
Book Synopsis Endothelial Dynamics in Health and Disease by : Jaap Diederik Van Buul
Download or read book Endothelial Dynamics in Health and Disease written by Jaap Diederik Van Buul and published by Frontiers Media SA. This book was released on 2021-01-06 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Immunological Aspects of the Vascular Endothelium by : Caroline O. S. Savage
Download or read book Immunological Aspects of the Vascular Endothelium written by Caroline O. S. Savage and published by Cambridge University Press. This book was released on 1995-09-07 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published in 1995, this volume looks at the functioning of the vascular endothelium, and the diseases and tissue injury that arise as a result of inflammation and immunological responses. The vascular endothelium is a metabolically highly active layer of cells lining all blood vessel walls. Through its interactions with leucocytes and other mediators, it is central to the development of inflammatory foci and to lymphocyte trafficking around the body. Tissue injury may arise here as a result of abnormal inflammatory or immune responses. The potential for such injury to contribute to autoimmune disease is discussed in this book, particularly in relation to autoimmune vascular disease of the renal, rheumatological and neurological systems, as well as in organ transplantation.
Book Synopsis Vascular Endothelium by : Allan D. Callow
Download or read book Vascular Endothelium written by Allan D. Callow and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a NATO ASI held in Limin Hersonissou, Greece, June 18-27, 1994.
Book Synopsis Immune Functions of the Vessel Wall by : Goran K Hansson
Download or read book Immune Functions of the Vessel Wall written by Goran K Hansson and published by CRC Press. This book was released on 1996-12-13 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesizes recent advances in immunology and vascular biology to examine interactions between the endothelium and the immune response system and the immunopathology involved in various forms of vascular damage, particularly atherosclerosis. Coverage includes the endothelium as an antigen presenting cell, chemokines in vascular pathophysiology, humoral immunity and vascular injury in xenograft rejection, and autoimmunity to oxidized lipoproteins. For scientists and physicians interested in immunology, inflammation, and cardiovascular disease states. Annotation copyrighted by Book News, Inc., Portland, OR
Book Synopsis Idiotypes in Medicine: Autoimmunity, Infection and Cancer by : R.C. Kennedy
Download or read book Idiotypes in Medicine: Autoimmunity, Infection and Cancer written by R.C. Kennedy and published by Elsevier. This book was released on 1997-11-19 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the most comprehensive review of the idiotypic network available. All the current knowledge of idiotypes of the various antibodies is incorporated in this volume. The pathogenic role of idiotypes in autoimmunity and cancer is reviewed in depth. The therapeutic part focusses on harnessing anti-idiotypes for treating autoimmunological disorders, and on the employment of idiotypes for vaccines in cancer and infectious diseases, as well as explaining the manipulation of the idiotypic network in autoimmunity and cancer idiotypes and vaccines.
Book Synopsis Inflammation and the Microcirculation by : D. Neil Granger
Download or read book Inflammation and the Microcirculation written by D. Neil Granger and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References
Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Book Synopsis Regulation of Endothelial Barrier Function by : Sarah Y. Yuan
Download or read book Regulation of Endothelial Barrier Function written by Sarah Y. Yuan and published by Biota Publishing. This book was released on 2011-02-01 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: The vascular endothelium lining the inner surface of blood vessels serves as the first interface for circulating blood components to interact with cells of the vascular wall and surrounding extravascular tissues. In addition to regulating blood delivery and perfusion, a major function of vascular endothelia, especially those in exchange microvessels (capillaries and postcapillary venules), is to provide a semipermeable barrier that controls blood–tissue exchange of fluids, nutrients, and metabolic wastes while preventing pathogens or harmful materials in the circulation from entering into tissues. During host defense against infection or tissue injury, endothelial barrier dysfunction occurs as a consequence as well as cause of inflammatory responses. Plasma leakage disturbs fluid homeostasis and impairs tissue oxygenation, a pathophysiological process contributing to multiple organ dysfunction associated with trauma, infection, metabolic disorder, and other forms of disease. In this book, we provide an updated overview of microvascular endothelial barrier structure and function in health and disease. The discussion is initiated with the basic physiological principles of fluid and solute transport across microvascular endothelium, followed by detailed information on endothelial cell–cell and cell–matrix interactions and the experimental techniques that are employed to measure endothelial permeability. Further discussion focuses on the signaling and molecular mechanisms of endothelial barrier responses to various stimulations or drugs, as well as their relevance to several common clinical conditions. Taken together, this book provides a comprehensive analysis of microvascular endothelial cell and molecular pathophysiology. Such information will assist scientists and clinicians in advanced basic and clinical research for improved health care.
Book Synopsis Vascular Endothelium by : John D. Catravas
Download or read book Vascular Endothelium written by John D. Catravas and published by Springer Science & Business Media. This book was released on 1991 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The focus of the June 1990 workshop (the second in as many years on endothelial biology): diseases, such as atherosclerosis, sepsis, ARDS, and stroke, based on their relevance to endothelial cell function and the need for new insights into their pathogenesis and treatment. Also examined in 22 papers
Book Synopsis Oxidative Stress and Vascular Disease by : John F. Keaney Jr.
Download or read book Oxidative Stress and Vascular Disease written by John F. Keaney Jr. and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major biomedical triumphs of the post-World War II era was the defmitive demonstration that hypercholesterolemia is a key causative factor in atherosclerosis; that hypercholesterolemia can be effectively treated; and that treatment significantly reduces not only coronary disease mortality but also all cause mortality. Treatment to lower plasma levels of cholesterol - primarily low density lipoprotein (LDL) cholesterol - is now accepted as best medical practice and both physicians and patients are being educated to take aggressive measures to lower LDL. We can confidently look forward to important decreases in the toll of coronary artery disease over the coming decades. However, there is still uncertainty as to the exact mechanisms by which elevated plasma cholesterol and LDL levels initiate and favor the progression of lesions. There is general consensus that one of the earliest responses to hypercholesterolemia is the adhesion of monocytes to aortic endothelial cells followed by their penetration into the subendothelial space, where they differentiate into macrophages. These cells, and also medial smooth muscle cells that have migrated into the subendothelial space, then become loaded with mUltiple, large droplets of cholesterol esters . . . the hallmark of the earliest visible atherosclerotic lesion, the so-called fatty streak. This lesion is the precursor of the more advanced lesions, both in animal models and in humans. Thus the centrality of hypercholesterolemia cannot be overstated. Still, the atherogenic process is complex and evolves over a long period of time.
