Effects of Chemical Carcinogens on Nucleic Acids, Proteins, and Chromosomes

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ISBN 13 :
Total Pages : 43 pages
Book Rating : 4.:/5 (353 download)

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Book Synopsis Effects of Chemical Carcinogens on Nucleic Acids, Proteins, and Chromosomes by : Current Cancer Research Project Analysis Center

Download or read book Effects of Chemical Carcinogens on Nucleic Acids, Proteins, and Chromosomes written by Current Cancer Research Project Analysis Center and published by . This book was released on 1980 with total page 43 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Aging, Carcinogenesis, and Radiation Biology

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Publisher : Springer Science & Business Media
ISBN 13 : 1475716621
Total Pages : 564 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Aging, Carcinogenesis, and Radiation Biology by : Kendric Smith

Download or read book Aging, Carcinogenesis, and Radiation Biology written by Kendric Smith and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: The covalent attachment to deoxyribonucleic acid in vivo of a large number of different types of chemical compounds (both normal cellular constituents such as proteins and amino acids, and also exogenous compounds such as drugs, carcinogens, etc. ) have been shown to exert profound effects upon cells. Four research activi ties, formerly considered to be totally independent, relate to this problem of nucleic acid adducts--(1) normal covalent attachment of DNA to membranes, protein linkers in chromosomes, etc. ; (2) the roles of radiation and chemical enhancement of DNA adduct formation in cell killing and mutagenesis. (A related field is the use of known cross-linking reactions to gain information on structural associations in macromolecular complexes. ); (3) the relevance of DNA adducts to chemical and radiation carcinogenesis; (4) the rele vance of DNA adducts to the cross-linking theory of cellular aging. (1) There are numerous examples of normal linkages between DNA and protein, e. g. , DNA-membrane attachment sites, protein linkers in chromosomes, amino acids covalently linked to DNA as a function of growth conditions, and gene regulation by non-covalently bound proteins. A summary of data on natural adducts to DNA thus serves to introduce the subject of the radiation and chemical enhancement of DNA adduct formation. (2) In the past, radiation biology has been concerned mainly with trying to understand the radiation chemistry of purified DNA, and the biological effects and repair of these radiation-induced alterations when produced in cellular DNA.

Current Cancer Research on Effects of Chemical Carcinogens on Nucleic Acids, Proteins, and Chromosomes

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ISBN 13 :
Total Pages : 43 pages
Book Rating : 4.:/5 (489 download)

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Book Synopsis Current Cancer Research on Effects of Chemical Carcinogens on Nucleic Acids, Proteins, and Chromosomes by : National cancer institute (Etats-Unis)

Download or read book Current Cancer Research on Effects of Chemical Carcinogens on Nucleic Acids, Proteins, and Chromosomes written by National cancer institute (Etats-Unis) and published by . This book was released on 1980 with total page 43 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Current Cancer Research on Effects of Chemical Carcinogens on Nucleic Acids, Proteins, and Chromosomes

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ISBN 13 :
Total Pages : 48 pages
Book Rating : 4.:/5 (143 download)

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Book Synopsis Current Cancer Research on Effects of Chemical Carcinogens on Nucleic Acids, Proteins, and Chromosomes by : Current Cancer Research Project Analysis Center (U.S.)

Download or read book Current Cancer Research on Effects of Chemical Carcinogens on Nucleic Acids, Proteins, and Chromosomes written by Current Cancer Research Project Analysis Center (U.S.) and published by . This book was released on 1978 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Effects of chemical carcinogens on nucleic acids, proteins, and chromosomes

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Publisher :
ISBN 13 :
Total Pages : 43 pages
Book Rating : 4.:/5 (16 download)

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Book Synopsis Effects of chemical carcinogens on nucleic acids, proteins, and chromosomes by :

Download or read book Effects of chemical carcinogens on nucleic acids, proteins, and chromosomes written by and published by . This book was released on 1980 with total page 43 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Current Cancer Research

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Publisher :
ISBN 13 :
Total Pages : 43 pages
Book Rating : 4.:/5 (693 download)

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Book Synopsis Current Cancer Research by :

Download or read book Current Cancer Research written by and published by . This book was released on 1980 with total page 43 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Special Listing of Current Cancer Research on Effects of Chemical Carcinogens on Nucleic Acids, Proteins, and Chromosomes

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Publisher :
ISBN 13 :
Total Pages : 25 pages
Book Rating : 4.:/5 (376 download)

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Book Synopsis Special Listing of Current Cancer Research on Effects of Chemical Carcinogens on Nucleic Acids, Proteins, and Chromosomes by : Current Cancer Research Project Analysis Center

Download or read book Special Listing of Current Cancer Research on Effects of Chemical Carcinogens on Nucleic Acids, Proteins, and Chromosomes written by Current Cancer Research Project Analysis Center and published by . This book was released on 1976 with total page 25 pages. Available in PDF, EPUB and Kindle. Book excerpt:

How Tobacco Smoke Causes Disease

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ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by : United States. Public Health Service. Office of the Surgeon General

Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Mechanisms of Chemical Carcinogenesis

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Publisher : Butterworth-Heinemann
ISBN 13 : 1483192466
Total Pages : 145 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis Mechanisms of Chemical Carcinogenesis by : D. E. Hathway

Download or read book Mechanisms of Chemical Carcinogenesis written by D. E. Hathway and published by Butterworth-Heinemann. This book was released on 2013-10-22 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanisms of Chemical Carcinogenesis provides information pertinent to the fundamental mechanisms of chemical carcinogenesis. This book surveys the interactions of chemical carcinogens with native DNA, the activation of normal cellular sequences, and the transforming role of the activated genes. Organized into seven chapters, this book begins with an overview of the relationship between the incidence of lung cancer and the frequency and duration of cigarette smoking. This text then examines the concept that carcinogens may require metabolic activation before they initiate carcinogenesis. Other chapters consider the structure of the nucleoside adducts resulting from the hydrolysis of salmon-sperm DNA and rat-liver ribosomal RNA. This book discusses as well the persistence of nucleoside analogues in target-tissue nucleic acid. The final chapter deals with mutational theory. This book is a valuable resource for workers involved with cancer research, toxicology, and molecular biology. Specialists in drug development, industrial hygiene and occupational medicine will also find this book useful.

Chemical Carcinogens & Dna

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Publisher : CRC Press
ISBN 13 : 0429536291
Total Pages : 344 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis Chemical Carcinogens & Dna by : Philip L. Grover

Download or read book Chemical Carcinogens & Dna written by Philip L. Grover and published by CRC Press. This book was released on 2019-06-04 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1979, Chemical Carcinogenesis and DNA is an essential guide to the relationship between mutagens, carcinogens and our own genetic makeup. Covering a range of associated topics, this volume provides information that would prove most beneficial for practitioners of medicine and students alike.

Comparative Oncology

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Publisher :
ISBN 13 : 9789732714577
Total Pages : 787 pages
Book Rating : 4.7/5 (145 download)

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Book Synopsis Comparative Oncology by : Alecsandru Ioan Baba

Download or read book Comparative Oncology written by Alecsandru Ioan Baba and published by . This book was released on 2007 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Veterans at Risk

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Publisher : National Academies Press
ISBN 13 : 030904832X
Total Pages : 448 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Veterans at Risk by : Institute of Medicine

Download or read book Veterans at Risk written by Institute of Medicine and published by National Academies Press. This book was released on 1993-02-01 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, World War II veterans have come forward to claim compensation for health effects they say were caused by their participation in chemical warfare experiments. In response, the Veterans Administration asked the Institute of Medicine to study the issue. Based on a literature review and personal testimony from more than 250 affected veterans, this new volume discusses in detail the development and chemistry of mustard agents and Lewisite followed by interesting and informative discussions about these substances and their possible connection to a range of health problems, from cancer to reproductive disorders. The volume also offers an often chilling historical examination of the use of volunteers in chemical warfare experiments by the U.S. militaryâ€"what the then-young soldiers were told prior to the experiments, how they were "encouraged" to remain in the program, and how they were treated afterward. This comprehensive and controversial book will be of importance to policymakers and legislators, military and civilian planners, officials at the Department of Veterans Affairs, military historians, and researchers.

Physical and Chemical Effects of Carcinogen Binding to DNA in Relation to Biological Activity and Statistical Problems in Chemical Carcinogenesis

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ISBN 13 :
Total Pages : 414 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Physical and Chemical Effects of Carcinogen Binding to DNA in Relation to Biological Activity and Statistical Problems in Chemical Carcinogenesis by : Norman R. Drinkwater

Download or read book Physical and Chemical Effects of Carcinogen Binding to DNA in Relation to Biological Activity and Statistical Problems in Chemical Carcinogenesis written by Norman R. Drinkwater and published by . This book was released on 1980 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chemical Carcinogens and DNA

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Publisher :
ISBN 13 :
Total Pages : 238 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Chemical Carcinogens and DNA by : Philip L. Grover

Download or read book Chemical Carcinogens and DNA written by Philip L. Grover and published by . This book was released on 1979 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chemical Carcinogenesis

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Publisher : Springer
ISBN 13 :
Total Pages : 520 pages
Book Rating : 4.:/5 (45 download)

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Book Synopsis Chemical Carcinogenesis by : Claudio Nicolini

Download or read book Chemical Carcinogenesis written by Claudio Nicolini and published by Springer. This book was released on 1982-10 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: During October 18-30, 1981, the second course of the International School of Pure and Applied Biostructure, a NATO Advanced Study Institute, was held at the Ettore Majorana Center for Scientific Culture in Erice, Italy, co-sponsored by the International Union Against Cancer, the Italian League Against Cancer, the Italian Ministry of Public Education, the Italian Ministry of Scientific and Technological Research, the North Atlantic Treaty Organization, the Italian National Research Council, the Sicilian Regional Government and two pharmaceutical Companies (Zambeletti and Farmitalia). The subject of the course was "Chemical Carcino genesis" with participants selected world-wide from 18 different countries. It is now eminently clear that.the bulk of human cancers are related to one of several types of environmental exposure. Of the environmental hazards, chemicals are among the best characterized carcinogens. However, how chemicals induce cancer is still poorly understood. Because of the magnitude of the problem and the ob vious need for a much more critical scientific analysis of the process by which cancer is induced (carcinogenesis), it was highly desirable to expose a greater number of scientists with varying background to some of the latest thinking in chemical carcino genesis. The course had this as its major objective and the re sulting book does reflect it.

Mechanisms of Carcinogenesis

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Publisher : Springer Science & Business Media
ISBN 13 : 9400925263
Total Pages : 210 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Mechanisms of Carcinogenesis by : Elizabeth K. Weisburger

Download or read book Mechanisms of Carcinogenesis written by Elizabeth K. Weisburger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: but also the possibility of intervention in specific stages. In Human behavior, including stress and other factors, plays an important role in neoplasia, although too little is known addition, variables which affect cancer development as well on the reasons for such development. Carcinogens, which as some endogenous factors can be better delineated help initiate the neoplastic process, may be either synthetic through such investigations. The topics of this volume encompass premalignant non or naturally-occurring. Cancer causation may be ascribed to invasive lesions, species-specific aspects of carcinogenicity, certain chemicals, physical agents, radioactive materials, viruses, parasites, the genetic make-up of the organism, and radiation, viruses, a quantum theory of carinogenesis, onco bacteria. Humans, eumetazoan animals and vascular plants genes, and selected environmental carcinogens. are susceptible to the first six groups of cancer causes, whe reas the last group, bacteria, seems to affect only vascular plants. Neoplastic development may begin with impairment ofJmdy defenses by a toxic material (carcinogen) which acts as an initiator, followed by promotion and progression to an overt neoplastic state. Investigation of these processes Series Editor Volume Editor allows not only a better insight into the mechanism of action Hans E. Kaiser Elizabeth K. Weisburger vii ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.

Carcinogens and Anticarcinogens in the Human Diet

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Publisher : National Academies Press
ISBN 13 : 0309175712
Total Pages : 433 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Carcinogens and Anticarcinogens in the Human Diet by : National Research Council

Download or read book Carcinogens and Anticarcinogens in the Human Diet written by National Research Council and published by National Academies Press. This book was released on 1996-02-12 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.