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Effect Of High Fat And High Fiber Diets On Proliferation And Differentiation Of Rat Colonic Epithelial Cells
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Book Synopsis Regulation of Gastrointestinal Mucosal Growth by : Rao N. Jaladanki
Download or read book Regulation of Gastrointestinal Mucosal Growth written by Rao N. Jaladanki and published by Biota Publishing. This book was released on 2016-11-30 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mammalian gastrointestinal mucosa is a rapidly self-renewing tissue in the body, and its homeostasis is preserved through the strict regulation of epithelial cell proliferation, growth arrest, and apoptosis. The control of the growth of gastrointestinal mucosa is unique and, compared with most other tissue in the body, complex. Mucosal growth is regulated by the same hormones that alter metabolism in other tissues, but the gastrointestinal mucosa also responds to host events triggered by the ingestion and presence of food within the digestive tract. These gut hormones and peptides regulate the growth of the exocrine pancreas, gallbladder epithelium, and the mucosa of the oxyntic gland region of the stomach and the small and large intestines. Luminal factors, including nutrients or other dietary factors, secretions, and microbes that occur within the lumen and distribute over a proximal-to-distal gradient, are also crucial for maintenance of normal gut mucosal regeneration and could explain the villous-height-crypt-depth gradient and variety of adaptation, since these factors are diluted, absorbed, and destroyed as they pass down the digestive tract. Recently, intestinal stem cells, cellular polyamines, and noncoding RNAs are shown to play an important role in the regulation of gastrointestinal mucosal growth under physiological and various pathological conditions. In this book, we highlight key issues and factors that control gastrointestinal mucosal growth and homeostasis, with special emphasis on the mechanisms through which epithelial renewal and apoptosis are regulated at the cellular and molecular levels.
Author :American Institute for Cancer Resea Publisher :Springer Science & Business Media ISBN 13 :1461541492 Total Pages :169 pages Book Rating :4.4/5 (615 download)
Book Synopsis Colon Cancer Prevention by : American Institute for Cancer Resea
Download or read book Colon Cancer Prevention written by American Institute for Cancer Resea and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Eighth Annual Research Conference of the American Institute for Cancer Research, held in Washington, D.C., September 3-4, 1998, was on the subject "Colon Cancer Prevention: Dietary Modulation of Cellular and Molecular Mechanisms," with participants representing various disciplines interested in this area. One of the speak ers provided an appropriate quote from 17th century physician Thomas Adams: "Pre vention is better than healing because it saves the labor of being sick," which aptly describes the need for the prevention of cancer. An overview of normal and abnormal colonic development emphasized that although the typical human colon undergoes 1013 cell divisions by age 60, with the asso ciated possibilities for error, relatively few colon tumors develop. Since dietary modu lation leads to extremely small changes in colonic cells over a long period, animal models are useful to time, observe, and delineate the events associated with colon cancer. In the development colon cancer, the inactivation of the adenomatous polyposis coli (Apc) gene is one of the earliest known events. Normally Apc downregulates the cellular protein beta-catenin, but this is lost during cancer development. Beta-catenin may itself be an oncogene; it has a short half-life, but it is stabilized by binding to is more prevalent in the cell nucleus, the gene shuttles caherin. Although the Apc between the nucleus and the cytoplasm.
Book Synopsis Missing Microbes by : Martin J. Blaser, MD
Download or read book Missing Microbes written by Martin J. Blaser, MD and published by Henry Holt and Company. This book was released on 2014-04-08 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: “In Missing Microbes, Martin Blaser sounds [an] alarm. He patiently and thoroughly builds a compelling case that the threat of antibiotic overuse goes far beyond resistant infections.”—Nature Renowned microbiologist Dr. Martin J. Blaser invites us into the wilds of the human microbiome, where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the equilibrium and health of our bodies. Now this invisible Eden is under assault from our overreliance on medical advances including antibiotics and caesarian sections, threatening the extinction of our irreplaceable microbes and leading to severe health consequences. Taking us into the lab to recount his groundbreaking studies, Blaser not only provides elegant support for his theory, he guides us to what we can do to avoid even more catastrophic health problems in the future. “Missing Microbes is science writing at its very best—crisply argued and beautifully written, with stunning insights about the human microbiome and workable solutions to an urgent global crisis.”—David M. Oshinsky, author of the Pulitzer Prize-winning Polio: An American Story
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1980 with total page 916 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Vegetables, Whole Grains, and Their Derivatives in Cancer Prevention by : Marja Mutanen
Download or read book Vegetables, Whole Grains, and Their Derivatives in Cancer Prevention written by Marja Mutanen and published by Springer Science & Business Media. This book was released on 2010-10-06 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vegetables, Whole Grains and their Derivatives in Cancer Prevention looks in detail at the evidence regarding the effects and mechanisms of action of potentially cancer-preventive components and their sources from plant kingdom. The book covers current knowledge on certain foods and their constituents in cancer prevention, such as cruciferous and green leafy vegetables, nuts and seeds, whole grains, tomato lycopene and carotenoids, alliums and their sulphur and selenium constituents, and capsaicinoids from chilli peppers. It focuses not only on single compounds but aims to widen the view by discussing a whole-diet approach in cancer prevention. A single component may lose its chemopreventive efficacy when isolated from the food matrix and in many cases isolated and concentrated components as supplements may actually induce tumor development. Apart from describing the effects and mechanisms of action, the chapters also contain information on intake, bioavailability, metabolism and possible toxic effects of foods and components presented. Evaluation and comparison of the data from mechanistic studies in vitro with those from animal experiments in vivo form a basis for applying the current knowledge to human nutrition in the field of carcinogenesis. With contributions from leading experts in the field, this book is an invaluable resource for scientists and professionals working in cancer research, as well as individuals involved in food and nutrition.
Book Synopsis Nutrient Requirements of Laboratory Animals, by : National Research Council
Download or read book Nutrient Requirements of Laboratory Animals, written by National Research Council and published by National Academies Press. This book was released on 1995-02-01 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the years since the third edition of this indispensable reference was published, a great deal has been learned about the nutritional requirements of common laboratory species: rat, mouse, guinea pig, hamster, gerbil, and vole. The Fourth Revised Edition presents the current expert understanding of the lipid, carbohydrate, protein, mineral, vitamin, and other nutritional needs of these animals. The extensive use of tables provides easy access to a wealth of comprehensive data and resource information. The volume also provides an expanded background discussion of general dietary considerations. In addition to a more user-friendly organization, new features in this edition include: A significantly expanded section on dietary requirements for rats, reporting substantial new findings. A new section on nutrients that are not required but that may produce beneficial results. New information on growth and reproductive performance among the most commonly used strains of rats and mice and on several hamster species. An expanded discussion of diet formulation and preparationâ€"including sample diets of both purified and natural ingredients. New information on mineral deficiency and toxicity, including warning signs. This authoritative resource will be important to researchers, laboratory technicians, and manufacturers of laboratory animal feed.
Book Synopsis Physiological and Clinical Aspects of Short-Chain Fatty Acids by : John H. Cummings
Download or read book Physiological and Clinical Aspects of Short-Chain Fatty Acids written by John H. Cummings and published by Cambridge University Press. This book was released on 2004-12-02 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive volume to look at the importance of short-chain fatty acids in digestion, the function of the large intestine and their role in human health. Short-chain fatty acids are the major product of bacterial fermentation of dietary carbohydrates in the human and animal large intestine. They represent the major end products of digestive processes occurring in the caecum and large intestine. As such, they form an important dietary component and it is increasingly recognised that they may have a significant role in protecting against large bowel cancer and in metabolism. Prepared by an international team of contributors who are at the forefront of this area of research, this volume will be an essential source of reference for gastroenterologists, nutritionists and others active in this area.
Book Synopsis Nutrition Abstracts and Reviews by :
Download or read book Nutrition Abstracts and Reviews written by and published by . This book was released on 2001 with total page 1024 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bulletin written by and published by . This book was released on 1997 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nutrition written by and published by . This book was released on 2000 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cancer Research written by and published by . This book was released on 1995 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Dietary Calcium in Health written by and published by . This book was released on 1997 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Bulletin of the World Health Organization by : World Health Organization
Download or read book Bulletin of the World Health Organization written by World Health Organization and published by . This book was released on 1990 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Free Fatty Acid Receptors by : Graeme Milligan
Download or read book Free Fatty Acid Receptors written by Graeme Milligan and published by Springer. This book was released on 2017-02-08 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the important role free fatty acids (FFA) play as potential drug targets. While FFA have long been considered byproducts of cell metabolism, they are now recognized as ligands that regulate cell and tissue function via G-protein-coupled receptors. At least three receptors have been identified for which FFA appear to be the endogenous ligands.
Book Synopsis The Australian Journal of Dairy Technology by :
Download or read book The Australian Journal of Dairy Technology written by and published by . This book was released on 2001 with total page 1060 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Sleisenger & Fordtran's Gastrointestinal and Liver Disease by : Marvin H. Sleisenger
Download or read book Sleisenger & Fordtran's Gastrointestinal and Liver Disease written by Marvin H. Sleisenger and published by . This book was released on 2006 with total page 1472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provide evidence-based perspectives on all clinically relevant topics, explaining step by step how to apply the latest advances in practice. Succinct yet comprehensive discussions provide just the right amount of clinical detail. Plus, a consistent organization and full-color art program enable you to quickly and easily access needed information. Offers more than 1,000 illustrations, photographs, and tables (400 in full color) that promote a visual grasp of the material. Presents coverage of the hottest topics in today's practice, including GERD, non-alcoholic fatty liver disease, ulcerative colitis, and Barretts esophagus, as well as the psychosocial aspects of gastrointestinal and liver diseases. Features four new chapters covering complimentary and alternative medicine palliative care gastrointestinal stromal tumor (GIST) and eosinophilic disorders, plus expanded information on obesity and nutrition.
Author :Dimitris Charalampopoulos Publisher :Springer Science & Business Media ISBN 13 :0387790578 Total Pages :1273 pages Book Rating :4.3/5 (877 download)
Book Synopsis Prebiotics and Probiotics Science and Technology by : Dimitris Charalampopoulos
Download or read book Prebiotics and Probiotics Science and Technology written by Dimitris Charalampopoulos and published by Springer Science & Business Media. This book was released on 2009-08-12 with total page 1273 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview on the advances in the field, this volume presents the science underpinning the probiotic and prebiotic effects, the latest in vivo studies, the technological issues in the development and manufacture of these types of products, and the regulatory issues involved. It will be a useful reference for both scientists and technologists working in academic and governmental institutes, and the industry.