Effect Of Glycogen Metabolism

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The Heterogeneity of Cancer Metabolism

Author : Anne Le
Publisher : Springer
ISBN 13 : 331977736X
Total Pages : 186 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis The Heterogeneity of Cancer Metabolism by : Anne Le

Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Medical Biochemistry

Author : N. V. Bhagavan
Publisher : Academic Press
ISBN 13 : 0120954400
Total Pages : 1068 pages
Book Rating : 4.1/5 (29 download)

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Book Synopsis Medical Biochemistry by : N. V. Bhagavan

Download or read book Medical Biochemistry written by N. V. Bhagavan and published by Academic Press. This book was released on 2002 with total page 1068 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents the fundamentals of biochemistry and related topics for all those pursuing medical or other health-related fields such as clinical chemistry, medical technology, or pharmacology.

Hormones, Metabolism and the Benefits of Exercise

Author : Bruce Spiegelman
Publisher : Springer
ISBN 13 : 3319727907
Total Pages : 108 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Hormones, Metabolism and the Benefits of Exercise by : Bruce Spiegelman

Download or read book Hormones, Metabolism and the Benefits of Exercise written by Bruce Spiegelman and published by Springer. This book was released on 2018-03-07 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.

Sports Endocrinology

Author : F. Lanfranco
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318058696
Total Pages : 182 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Sports Endocrinology by : F. Lanfranco

Download or read book Sports Endocrinology written by F. Lanfranco and published by Karger Medical and Scientific Publishers. This book was released on 2016-06-28 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an up-to-date, extensive overview of the effects of physical activity and training on endocrine function. It gives insights into a complex relationship by describing effects with respect to exercise performance, growth, development, and ageing. It includes discussions of the endocrine response depending on exercise mode, intensity, and duration as well as on gender, age, and fitness level. Additionally the book deals with the impact of environmental and psychological factors on endocrine level. A substantial part of Sports Endocrinology is devoted to the 'hot topic' of hormonal doping in sports. The properties of androgens, growth hormone, erythropoietin, and dietary supplements are highlighted. The use and abuse among professional and recreational athletes is discussed and specific methods of detection are presented and explained. All contributors are well-known experts in sports medicine and endocrinology, endocrine physiology, pharmacology, and doping detection, so this book is a must-read for every professional involved in the field.

Comparative Physiology of Fasting, Starvation, and Food Limitation

Author : Marshall D. McCue
Publisher : Springer Science & Business Media
ISBN 13 : 3642290566
Total Pages : 431 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Comparative Physiology of Fasting, Starvation, and Food Limitation by : Marshall D. McCue

Download or read book Comparative Physiology of Fasting, Starvation, and Food Limitation written by Marshall D. McCue and published by Springer Science & Business Media. This book was released on 2012-05-17 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: All animals face the possibility of food limitation and ultimately starvation-induced mortality. This book summarizes state of the art of starvation biology from the ecological causes of food limitation to the physiological and evolutionary consequences of prolonged fasting. It is written for an audience with an understanding of general principles in animal physiology, yet offers a level of analysis and interpretation that will engage seasoned scientists. Each chapter is written by active researchers in the field of comparative physiology and draws on the primary literature of starvation both in nature and the laboratory. The chapters are organized among broad taxonomic categories, such as protists, arthropods, fishes, reptiles, birds, and flying, aquatic, and terrestrial mammals including humans; particularly well-studied animal models, e.g. endotherms are further organized by experimental approaches, such as analyses of blood metabolites, stable isotopes, thermobiology, and modeling of body composition.

Protein C and Related Proteins

Author : Rogier M. Bertina
Publisher :
ISBN 13 :
Total Pages : 252 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Protein C and Related Proteins by : Rogier M. Bertina

Download or read book Protein C and Related Proteins written by Rogier M. Bertina and published by . This book was released on 1988 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Elsevier's Integrated Review Biochemistry

Author : John W. Pelley, PhD
Publisher : Elsevier Health Sciences
ISBN 13 : 0323074464
Total Pages : 254 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Elsevier's Integrated Review Biochemistry by : John W. Pelley, PhD

Download or read book Elsevier's Integrated Review Biochemistry written by John W. Pelley, PhD and published by Elsevier Health Sciences. This book was released on 2011-11-30 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Effectively merge basic science and clinical skills with Elsevier's Integrated Review Biochemistry, by John W. Pelley, PhD. This concise, high-yield title in the popular Integrated Review Series focuses on the core knowledge in biochemistry while linking that information to related concepts from other basic science disciplines. Case-based questions at the end of each chapter enable you to gauge your mastery of the material, and a color-coded format allows you to quickly find the specific guidance you need. Online access via www.studentconsult.com - included with your purchase - allows you to conveniently access the book's complete text and illustrations online as well as relevant content from other Student Consult titles. This concise and user-friendly reference provides crucial guidance for the early years of medical training and USMLE preparation. Spend more time reviewing and less time searching thanks to an extremely focused, "high-yield" presentation. Gauge your mastery of the material and build confidence with both case-based, andUSMLE-style questions that provide effective chapter review and quick practice for your exams. Access the full contents online at www.studentconsult.com where you'll find the complete text and illustrations, "Integration Links" to bonus content in other Student Consult titles, an interactive community center with a wealth of additional resources, and much more! Grasp and retain vital concepts more easily thanks to a color-coded format, succinct,text, key concept boxes, and dynamic illustrations that facilitate learning in a highly visual approach. Effectively review for problem-based courses with the help of text boxes that help you clearly see the clinical relevance of the material. Great for visual learners!

Essentials of Medical Biochemistry

Author : Chung Eun Ha
Publisher : Academic Press
ISBN 13 : 0080916880
Total Pages : 600 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Essentials of Medical Biochemistry by : Chung Eun Ha

Download or read book Essentials of Medical Biochemistry written by Chung Eun Ha and published by Academic Press. This book was released on 2011-01-28 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expert biochemist N.V. Bhagavan’s new work condenses his successful Medical Biochemistry texts along with numerous case studies, to act as an extensive review and reference guide for both students and experts alike. The research-driven content includes four-color illustrations throughout to develop an understanding of the events and processes that are occurring at both the molecular and macrolecular levels of physiologic regulation, clinical effects, and interactions. Using thorough introductions, end of chapter reviews, fact-filled tables, and related multiple-choice questions, Bhagavan provides the reader with the most condensed yet detailed biochemistry overview available. More than a quick survey, this comprehensive text includes USMLE sample exams from Bhagavan himself, a previous coauthor. Clinical focus emphasizing relevant physiologic and pathophysiologic biochemical concepts Interactive multiple-choice questions to prep for USMLE exams Clinical case studies for understanding basic science, diagnosis, and treatment of human diseases Instructional overview figures, flowcharts, and tables to enhance understanding

EFFECT OF GLYCOGEN METABOLISM

Author : Pui-Ying Tam
Publisher : Open Dissertation Press
ISBN 13 : 9781361018187
Total Pages : 132 pages
Book Rating : 4.0/5 (181 download)

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Book Synopsis EFFECT OF GLYCOGEN METABOLISM by : Pui-Ying Tam

Download or read book EFFECT OF GLYCOGEN METABOLISM written by Pui-Ying Tam and published by Open Dissertation Press. This book was released on 2017-01-26 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "The Effect of Glycogen Metabolism on the Regulation of Reactive Oxidative Species Level in Cultured Cancer Cells" by Pui-ying, Tam, 譚佩盈, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Glycogen is known to act as a fuel reserve in organs such as skeletal muscle and liver. Glycogen is also known to accumulate in many cancer cells suggesting a possible role for glycogen metabolism in cancers. Recently, studies using cancer cells that do not express glycogen phosphorylase showed that these cells had elevated level of reactive oxygen species (ROS). How inhibition of expression of glycogen phosphorylase may lead to increase in ROS level in tumour cells is not certain. It is hypothesised in this study that the accumulation of glycogen resulting from inhibition of its breakdown may lead to ROS production. Results of this study showed that inhibition of expression of glycogen synthase (GS) lead to almost 100% absence of glycogen and increase in intracellular ROS in the GS knockout cells. When compared to wild type cells, ROS level of cells lacking GS were higher irrespective of the absence or presence of glucose or glutamine. However, both wild type cells and GS knockout cells had similar levels of ROS in the absence of both glucose and glutamine. It is concluded that glycogen accumulation does not contribute to the increase of ROS due to inhibition of expression of glycogen synthase. Furthermore, the results of this study suggested that both wild type and GS knockout cells produce same amount of ROS through glucose and glycogen metabolism. Additional experiments demonstrated GS knockout cells exhibited increase expression of catalase, thioredoxin and Nrf2. Suggesting that the antioxidant mechanisms are involved in counteracting the increase in oxidative stress in GS knockout cells. Subjects: Glycogen - Metabolism Oxidative stress

Control of Glycogen Metabolism

Author : W. J. Whelan
Publisher : John Wiley & Sons
ISBN 13 : 0470716886
Total Pages : 336 pages
Book Rating : 4.4/5 (77 download)

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Book Synopsis Control of Glycogen Metabolism by : W. J. Whelan

Download or read book Control of Glycogen Metabolism written by W. J. Whelan and published by John Wiley & Sons. This book was released on 2009-09-16 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Fructose, High Fructose Corn Syrup, Sucrose and Health

Author : James M. Rippe
Publisher : Springer Science & Business Media
ISBN 13 : 1489980776
Total Pages : 389 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Fructose, High Fructose Corn Syrup, Sucrose and Health by : James M. Rippe

Download or read book Fructose, High Fructose Corn Syrup, Sucrose and Health written by James M. Rippe and published by Springer Science & Business Media. This book was released on 2014-02-21 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: The metabolic and health effects of both nutritive and non-nutritive sweeteners are controversial, and subjects of intense scientific debate. These potential effects span not only important scientific questions, but are also of great interest to media, the public and potentially even regulatory bodies. Fructose, High Fructose Corn Syrup, Sucrose and Health serves as a critical resource for practice-oriented physicians, integrative healthcare practitioners, academicians involved in the education of graduate students and post-doctoral fellows, and medical students, interns and residents, allied health professionals and nutrition researchers, registered dietitians and public health professions who are actively involved in providing data-driven recommendations on the role of sucrose, HFCS, glucose, fructose and non-nutritive sweeteners in the health of their students, patients and clients. Comprehensive chapters discuss the effects of both nutritive and non-nutritive sweeteners on appetite and food consumption as well as the physiologic and neurologic responses to sweetness. Chapter authors are world class, practice and research oriented nutrition authorities, who provide practical, data-driven resources based upon the totality of the evidence to help the reader understand the basics of fructose, high fructose corn syrup and sucrose biochemistry and examine the consequences of acute and chronic consumption of these sweeteners in the diets of young children through to adolescence and adulthood. Fructose, High Fructose Corn Syrup, Sucrose and Health fills a much needed gap in the literature and will serve the reader as the most authoritative resource in the field to date.

Brain Glycogen Metabolism

Author : Mauro DiNuzzo
Publisher : Springer Nature
ISBN 13 : 3030274802
Total Pages : 443 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Brain Glycogen Metabolism by : Mauro DiNuzzo

Download or read book Brain Glycogen Metabolism written by Mauro DiNuzzo and published by Springer Nature. This book was released on 2019-10-31 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to provide a state-of-the-art summary of what is currently known about brain glycogen metabolism, detailing the recent advances in our understanding of why glycogen is so critical for normal brain function. The role of glycogen in cellular neurophysiology remains largely unclear and its specific contribution to the energy demand of brain cells is still elusive.Glycogen is the sole cerebral glucose reserve and is emerging as a fundamental component of brain energy metabolism. Pharmacological or genetic manipulation of glycogen metabolism in the brain impairs memory formation and increases susceptibility to epileptic seizures and cortical spreading depression. Glycogen is also directly implicated in abnormal neuronal excitability and mental retardation that characterize brain disorders like Lafora disease and Pompe disease.

Carbohydrate Metabolism in Health and Disease

Author : Javier T. Gonzalez
Publisher : MDPI
ISBN 13 : 3038429996
Total Pages : 267 pages
Book Rating : 4.0/5 (384 download)

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Book Synopsis Carbohydrate Metabolism in Health and Disease by : Javier T. Gonzalez

Download or read book Carbohydrate Metabolism in Health and Disease written by Javier T. Gonzalez and published by MDPI. This book was released on 2018-07-04 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Carbohydrate Metabolism in Health and Disease" that was published in Nutrients

Medical Biochemistry

Author : Antonio Blanco
Publisher : Academic Press
ISBN 13 : 0323916007
Total Pages : 910 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Medical Biochemistry by : Antonio Blanco

Download or read book Medical Biochemistry written by Antonio Blanco and published by Academic Press. This book was released on 2022-03-23 with total page 910 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of Medical Biochemistry is supported by more than 45 years of teaching experience, providing coverage of basic biochemical topics, including the structural, physical, and chemical properties of water, carbohydrates, lipids, proteins, and nucleic acids. In addition, the general aspects of thermodynamics, enzymes, bioenergetics, and metabolism are presented in straightforward and easy-to-comprehend language. This book ties these concepts into more complex aspects of biochemistry using a systems approach, dedicating chapters to the integral study of biological phenomena, including cell membrane structure and function, gene expression and regulation, protein synthesis and post-translational modifications, metabolism in specific organs and tissues, autophagy, cell receptors, signal transduction pathways, biochemical bases of endocrinology, immunity, vitamins and minerals, and hemostasis. The field of biochemistry is continuing to grow at a fast pace. This edition has been revised and expanded with all-new sections on the cell plasma membrane, the human microbiome, autophagy, noncoding, small and long RNAs, epigenetics, genetic diseases, virology and vaccines, cell signaling, and different modes of programmed cell death. The book has also been updated with full-color figures, new tables, chapter summaries, and further medical examples to improve learning and better illustrate the concepts described and their clinical significance. Integrates basic biochemistry principles with molecular biology and molecular physiology Illustrates basic biochemical concepts through medical and physiological examples Utilizes a systems approach to understanding biological phenomena Fully updated for recent studies and expanded to include clinically relevant examples and succinct chapter summaries

Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases

Author : Solomon Habtemariam
Publisher : Academic Press
ISBN 13 : 0081029233
Total Pages : 1180 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases by : Solomon Habtemariam

Download or read book Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases written by Solomon Habtemariam and published by Academic Press. This book was released on 2019-06-08 with total page 1180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases: The Chemical and Pharmacological Basis of their Action focuses on active pharmacological principles that modulate diabetes, associated risk factors, complications and the mechanism of action of widely used anti-diabetic herbal plants—rather than just the nutritional composition of certain foods. The book provides up-to-date information on acclaimed antidiabetic super fruits, spices and other food ingredients. Sections cover diabetes and obesity at the global level, the physiological control of carbohydrate and lipid metabolism, the pathophysiology of type-2 diabetes, the chemistry and pharmacology of a variety of spices, and much more. This book will be invaluable for research scientists and students in the medical and pharmaceutical sciences, medicinal chemistry, herbal medicine, drug discovery/development, nutrition science, and for herbal practitioners and those from the nutraceutical and pharm industries. Provides background knowledge on type-2 diabetes and its pathophysiology and therapeutic targets down to the molecular level Explores, in detail, the chemistry or secondary metabolites of the indicated foods that potentially modify diabetes and/or associated diseases Examines the pharmacological findings on medicinal foods, including available clinical trials

The Effect of Endotoxins on Hepatic Glycogen Metabolism

Author : Peter Zwadyk
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis The Effect of Endotoxins on Hepatic Glycogen Metabolism by : Peter Zwadyk

Download or read book The Effect of Endotoxins on Hepatic Glycogen Metabolism written by Peter Zwadyk and published by . This book was released on 1971 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Volpe's Neurology of the Newborn E-Book

Author : Joseph J. Volpe
Publisher : Elsevier Health Sciences
ISBN 13 : 0323508650
Total Pages : 1526 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Volpe's Neurology of the Newborn E-Book by : Joseph J. Volpe

Download or read book Volpe's Neurology of the Newborn E-Book written by Joseph J. Volpe and published by Elsevier Health Sciences. This book was released on 2017-09-13 with total page 1526 pages. Available in PDF, EPUB and Kindle. Book excerpt: A clear, engaging writing style, hundreds of full-color images, and new information throughout make Volpe’s Neurology of the Newborn, 6th Edition, an indispensable resource for those who provide care for neonates with neurological conditions. World authority Dr. Joseph Volpe, along with Dr. Terrie E. Inder and other distinguished editors, continue the unparalleled clarity and guidance you’ve come to expect from the leading reference in the field – keeping you up to date with today’s latest advances in diagnosis and management, as well as the many scientific and technological advances that are revolutionizing neonatal neurology. Features a brand new, full-color design with hundreds of new figures, tables, algorithms, and micrographs. Includes two entirely new chapters: Neurodevelopmental Follow-Up and Stroke in the Newborn; a new section on Neonatal Seizures; and an extensively expanded section on Hypoxic-Ischemia and Other Disorders. Showcases the experience and knowledge of a new editorial team, led by Dr. Joseph Volpe and Dr. Terrie E. Inder, Chair of the Department of Pediatric Newborn Medicine at Brigham and Women’s Hospital, all of whom bring a wealth of insight to this classic text. Offers comprehensive updates from cover to cover to reflect all of the latest information regarding the development of the neural tube; prosencephalic development; congenital hydrocephalus; cerebellar hemorrhage; neuromuscular disorders and genetic testing; and much more. Uses an improved organization to enhance navigation.