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Dynamics Of Cholinergic Function
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Book Synopsis Dynamics of Cholinergic Function by : Israel Hanin
Download or read book Dynamics of Cholinergic Function written by Israel Hanin and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 1242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book incorporates the proceedings of the Fifth International Cholinergic Conference, which took place in Oglebay Park, West Vir ginia, USA, on October 30th to November 4th, 1983. A scenic forty five minute ride from the City of Pittsburgh, surrounded by champion ship golf courses, luxurious woods and a picturesque lake, Oglebay provided relaxed and beautiful surroundings, conducive to contem plation, stimulating discussions and, thought-provoking scientific sessions. Over 160 individuals from allover the world participated in the sessions. The meeting was sub-divided into oral presentations, round table discussions and poster sessions, and centered upon ten key topics of cholinergic relevance (see Table of Contents). Following in the tradition of the four International Conferences which had preceded this one, the Conference featured the most up to-date developments in the area of cholinergic mechanisms, and provided for ample and productive discussion of new fields and di rections in this area. Moreover, both senior investigators in the field as well as recent newcomers to this sphere of investigation participated in the proceedings. This book, touches on a wide array of mechanisms and applications - from the preclinical to the clinical level. It should thus be useful as a comprehensive resource, with the cholinergic system as a focal hub. The Conference could not have been as successful as it turned out to be, without the support of a number of important contributors.
Book Synopsis Behavioral Pharmacology of the Cholinergic System by : Mohammed Shoaib
Download or read book Behavioral Pharmacology of the Cholinergic System written by Mohammed Shoaib and published by Springer Nature. This book was released on 2020-08-29 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: The molecular genetics of the cholinergic system including both muscarinic and nicotinic acetylcholine receptors, cholinesterases, acetylcholine synthesis and release have provided significant insights into potential targeting for pharmacological intervention. Cholinergic drugs are being used or evaluated for the treatment of diseases. Thus, this volume aims to broaden our understanding of the current state of cholinergic mechanisms to enable implementation of novel approaches for the development of more effective treatments.
Book Synopsis Cholinergic Function and Dysfunction by :
Download or read book Cholinergic Function and Dysfunction written by and published by Elsevier. This book was released on 1993-09-09 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cholinergic Function and Dysfunction
Book Synopsis Brain Cholinergic Systems by : Mircea Steriade
Download or read book Brain Cholinergic Systems written by Mircea Steriade and published by Oxford ; Toronto : Oxford University Press. This book was released on 1990 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, brain cholinergic systems are examined by leading authorities drawn from the fields of morphology, immunochemistry, electrophysiology, behaviour, and the study of cognitive disorders. The book covers major aspects of the organization and connectivity of cholinergic systems at thelight and electron-microscopic levels, intrinsic electrophysiological properties, and ionic conductances of central cholinergic neurons. It also discusses the effects of brainstem and basal forebrain cholinergic systems upon thalamic and cortical neurons, plasticity processes in the thalamins andcerebral cortex; and studies on Alzheimer's disease.
Book Synopsis Acetylcholine in the Cerebral Cortex by : L. Descarries
Download or read book Acetylcholine in the Cerebral Cortex written by L. Descarries and published by Elsevier. This book was released on 2004 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive exposé, by leading neuroscientists, of current knowledge on the neurotransmitter acetylcholine in the cerebral cortex. All aspects of the subject are covered, from its most elementary, at the molecular and cellular levels, to its systemic and holistic implications, including its role in cognition and involvement in human diseases and therapeutics. The twenty-two chapters are grouped under four main headings : I. Functional Morphology of the Acetylcholine Innervation in Cerebral Cortex (Including Hippocampus); II. Modes of Action of Acetylcholine in the Cerebral Cortex; III. Cortical Properties and Functions Modulated by Acetylcholine, and IV. Clinical, Pathological and Therapeutic Implications. This broad perspective updates the reader on recent advances and future trends in the study of a major neuromodulatory system in brain.
Book Synopsis The Orexin System. Basic Science and Role in Sleep Pathology by : M.A. Steiner
Download or read book The Orexin System. Basic Science and Role in Sleep Pathology written by M.A. Steiner and published by Karger Medical and Scientific Publishers. This book was released on 2021-05-28 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: The orexin system, discovered in 1998, has emerged as a crucial player in regulating the sleep and wake balance inside our brain. This discovery has sparked a burst of novel and dynamic research on the physiology and pathology of sleep. The Orexin System: Basic Science and Role in Sleep Pathology honors this research and the authors share their ideas and perspectives on the novel developments within the field. The book examines the intricate role of the orexin system in regulating sleep and wake, and its interaction with other wake-regulating systems. The orexin system is dissected at the cellular and molecular level to explore the diversity of the orexin-producing neurons, their projections, and their signaling pathways. Additionally, the book discusses the diseases which are associated with a dysfunctional orexin system, such as narcolepsy, insomnia, substance abuse, and Alzheimer’s disease, and explores the new potential therapeutic applications derived from the burst of research around this fascinating system. This publication is essential reading for neurobiologists, neurologists, psychopharmacologists, sleep researchers, and other researchers and clinical scientists interested in sleep, sleep research, insomnia, and medicine in general.
Author :Alexander G. Karczmar Publisher :Springer Science & Business Media ISBN 13 :038746526X Total Pages :698 pages Book Rating :4.3/5 (874 download)
Book Synopsis Exploring the Vertebrate Central Cholinergic Nervous System by : Alexander G. Karczmar
Download or read book Exploring the Vertebrate Central Cholinergic Nervous System written by Alexander G. Karczmar and published by Springer Science & Business Media. This book was released on 2007-04-05 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: Even if the “weapons of mass destruction” (WMD) and, among them, stocks of organoph- phorus (OP) agents (also referred to as war gases and nerve gases) were not found in Iraq following the US-Iraq war, the relative ease with which these substances can be made from harmless precursors and the low cost of their manufacture will continue to fascinate pow- hungry, ruthless dictators, as well as multinational and international terrorists, particularly as the close relationship between the OP agents and useful insecticides makes it easy to disguise the importation and purchase of small amounts of the precursors. Indeed, the use by Saddam Hussein of a nerve gas against the Kurds and his possible employment of the OP agents during his war with Iran, and the Sarin attack in the Tokyo underground by an extremist religious set magnetized the world with respect to the OP drugs. As these drugs exert their toxicity via their cholinergic action on the nervous, particularly central nervous, system, it is no wonder that the research in the cholinergic ? eld attracts, and merits, our intense attention. These considerations underlie the signi? cance of this book, as Alex Karczmar devotes an entire chapter of Exploring the Vertebrate Central Cholinergic Nervous System to anticholinest- ases (antiChEs), and as he is an acknowledged expert in the ? eld of cholinergic toxicity as well as a consultant to the Surgeon General of the U. S. Army.
Book Synopsis Movement Disorders by : Mark S. LeDoux
Download or read book Movement Disorders written by Mark S. LeDoux and published by Elsevier. This book was released on 2005-01-25 with total page 821 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of animal models is a key aspect of scientific research in numerous fields of medicine. This book vigorously examines the important contributions and application of animal models to the understanding of human movement disorders and will serve as an essential resource for basic neuroscientists engaged in movement disorders research. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in different animal models to the clinical features, pathophysiology and treatment of human movement disorders. A vital feature of this book is an accompanying DVD with video clips of human movement disorders and their corresponding animal models. The book is divided into sections on Parkinson disease, Huntington disease, dystonia, tremor, paroxysmal movement disorders, ataxia, myoclonus, restless legs syndrome, drug-induced movement disorders, multiple system atrophy, progressive supranuclear palsy/corticobasal degeneration and spasticity. This book serves as an essential resource for both clinicians interested in the science being generated with animal models and basic scientists studying the pathogenesis of particular movement disorders. * Provides a single comprehensive resource on animal models of movement disorders that academic clinicians, translational researchers, and basic neuroscientists can refer to* Includes contributions by expert movement disorder clinicians and top-level researchers in the field* Features a DVD containing over 170 video clips of human movement disorders and the corresponding animal models
Book Synopsis The Mouse Nervous System by : Charles Watson
Download or read book The Mouse Nervous System written by Charles Watson and published by Academic Press. This book was released on 2011-11-28 with total page 815 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Mouse Nervous System provides a comprehensive account of the central nervous system of the mouse. The book is aimed at molecular biologists who need a book that introduces them to the anatomy of the mouse brain and spinal cord, but also takes them into the relevant details of development and organization of the area they have chosen to study. The Mouse Nervous System offers a wealth of new information for experienced anatomists who work on mice. The book serves as a valuable resource for researchers and graduate students in neuroscience. Systematic consideration of the anatomy and connections of all regions of the brain and spinal cord by the authors of the most cited rodent brain atlases A major section (12 chapters) on functional systems related to motor control, sensation, and behavioral and emotional states A detailed analysis of gene expression during development of the forebrain by Luis Puelles, the leading researcher in this area Full coverage of the role of gene expression during development and the new field of genetic neuroanatomy using site-specific recombinases Examples of the use of mouse models in the study of neurological illness
Book Synopsis The Effects of Drug Abuse on the Human Nervous System by : Bertha Madras
Download or read book The Effects of Drug Abuse on the Human Nervous System written by Bertha Madras and published by Elsevier. This book was released on 2013-11-15 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug use and abuse continues to thrive in contemporary society worldwide and the instance and damage caused by addiction increases along with availability. The Effects of Drug Abuse on the Human Nervous System presents objective, state-of-the-art information on the impact of drug abuse on the human nervous system, with each chapter offering a specific focus on nicotine, alcohol, marijuana, cocaine, methamphetamine, MDMA, sedative-hypnotics, and designer drugs. Other chapters provide a context for drug use, with overviews of use and consequences, epidemiology and risk factors, genetics of use and treatment success, and strategies to screen populations and provide appropriate interventions. The book offers meaningful, relevant and timely information for scientists, health-care professionals and treatment providers. A comprehensive reference on the effects of drug addiction on the human nervous system Focuses on core drug addiction issues from nicotine, cocaine, methamphetamine, alcohol, and other commonly abused drugs Includes foundational science chapters on the biology of addiction Details challenges in diagnosis and treatment options
Book Synopsis Insect Nicotinic Acetylcholine Receptors by : Steeve Hervé Thany
Download or read book Insect Nicotinic Acetylcholine Receptors written by Steeve Hervé Thany and published by Springer Science & Business Media. This book was released on 2011-01-11 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to summarize our understanding on the insect nicotinic acetylcholine receptors. This area of research received great impetus from the identification of the first subunit sequences to be used as neonicotinoid insecticide target sites. Although a book of this nature can provide the details only of commonly published results, it is hoped that it may provide a useful guide to the newcomer to the field as well as to point out some of the future challenges. For example, we need to determine the precise subunit nomenclature of insect nicotinic receptors. This nomenclature varies amongst species and this led to some of the early confusion that persists. We need to be precise in identifying the subunit composition of native insect nicotinic receptor subtypes, their functional properties and physiological roles.
Book Synopsis Alzheimer Disease by : Robert Becker
Download or read book Alzheimer Disease written by Robert Becker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Brody's Human Pharmacology by : Lynn Wecker
Download or read book Brody's Human Pharmacology written by Lynn Wecker and published by Elsevier Health Sciences. This book was released on 2018-05-31 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on the essential aspects of pharmacology you need to know, Brody‘s Human Pharmacology, 6th Edition, keeps you fully up to date with all that’s new in the field. Streamlined content, a new organizational approach, and thoroughly updated information ensure your grasp of key concepts and prepare you for exams. Nearly 500 full-color illustrations explain important processes, while color-coded boxes for major drugs, therapeutic overviews, clinical problems, and trade names reinforce your mastery of the information. The 6th Edition of this easy-to-use text is now fully up to date with: NEW chapter devoted entirely to pharmacogenomics and personalized medicine. NEW chapter on cannabinoids and their use for pain and other disorders, in light of recent legalization in many states. NEW chapters on recent developments in the treatment of Alzheimer's disease, ADHD and the latest treatments for HIV. NEW section on pain management. NEW section in each chapter covering "Clinical Relevance for Healthcare Professionals" that provides important information specific to physical therapists, dentists and dental hygienists, and many other medical professionals. Plus these student-friendly features: A new organizational approach, focusing on integration and systems-based learning. Contributions from leading faculty who cover the most important aspects of pharmacology necessary for a basic understanding of the subject, including concepts, clinical applications, and side effects. USMLE-style self-assessment questions at the end of every chapter, answers and rationales in the Appendix. Evolve Instructor Resources, including a downloadable image and test bank, are available to instructors through their Elsevier sales rep or via request at: https://evolve.elsevier.com
Book Synopsis The Cholinergic Synapse by : Victor P. Whittaker
Download or read book The Cholinergic Synapse written by Victor P. Whittaker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most impressive works of scholarship in the field of experimental pharmacology has been the Heffter-Heubner Handbuch der experimentellen Pharmakologie, internationalized some years ago under the title Handbook 0/ Experimental Pharmacology and kept up to date by a series of numbered Ergiin zungswerke or supplementary volumes which have now replaced in importance the original Handbuch. These volumes constitute a valuable and continuously up dated multi author review series of topics important in modern pharmacology and allied sciences. The Editorial Board of the Handbook invited me 2 years ago to undertake, as subeditor, the preparation of a new volume entitled The Cholinergic Synapse. A previous volume in this series, vol. 15, Cholinesterases and Anticholinesterase Agents, edited by GEORGE KOELLE, was published in 1963 and was far wider in scope than its title suggested: it was, in fact an authoritative summing up of the whole subject of cholinergic function and still has some value today as an account of the state of the art as it was at that time. Since then another excellent review, of a specific cholinergic synapse, has appeared in this series: this was vol. 42, Neuromuscular Junction, edited by ELEANOR ZAIMIS and published in 1976. A third volume, vol. 53, Pharmacology o/Ganglionic Transmission, which appeared in 1980 and was edited by D. A. KHARKEVICH, includes important aspects of autonomic cholinergic function.
Book Synopsis Autonomic Failure by : Roger Bannister
Download or read book Autonomic Failure written by Roger Bannister and published by Oxford University Press, USA. This book was released on 1983 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: Life is a journey and we all have to go thru this progress. When I make wrong choices it was for a reason, it was for a purpose. I had to learn from it.I can not be ashamed of No one.I can not think that I am better then No One Else.I can not think less of No one Else.I can not talk about No One.Because My Father was not ashamed of Me.Because My Father did not think less of Me.Because My Father did not talk about my dirt or my sins to Anyone.Because My Father did not think that he was Better then me.HE ONLY LOVE ME
Book Synopsis Cognitive Changes and the Aging Brain by : Kenneth M. Heilman
Download or read book Cognitive Changes and the Aging Brain written by Kenneth M. Heilman and published by Cambridge University Press. This book was released on 2019-12-05 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the changes in the brain and in cognitive functions that occur with aging in the absence of a neurological, psychiatric, or medical disease. It discusses aging-related changes in many brain functions, including memory, language, sensory perception, motor function, creativity, attention, executive functions, emotions and mood. The neural mechanisms that may account for specific aging-related changes in cognition, perception and behavior are explored, as well as the means by which aging-related cognitive decrements can be managed and possibly ameliorated. Consequently, this book will be of value to clinicians, including neurologists, psychiatrists, geriatricians, primary care physicians, psychologists and speech-language pathologists. In addition, researchers and graduate students who want to learn about the aging brain will find this an indispensable guide.
Book Synopsis Introduction to Neuropsychopharmacology by : Leslie Iversen
Download or read book Introduction to Neuropsychopharmacology written by Leslie Iversen and published by Oxford University Press. This book was released on 2009 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: The text ranges from drugs that affect the mood and behavior to hypnotics, narcotics, anticonvulsants, and analgesics, as well as a variety of drugs that affect the autonomic nervous system and psychoactive drugs used for non-medical reasons - nicotine, alcohol, opiates, psychostimulants and cannabis."--BOOK JACKET.
