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Author : Caroline Pouget-Jasson
Publisher :
ISBN 13 :
Total Pages : 48 pages
Book Rating : 4.:/5 (12 download)
Download or read book Drug Re-challenges in Cutaneous Adverse Drug Reactions written by Caroline Pouget-Jasson and published by . This book was released on 2009 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sylvia Helena Kardaun
Publisher :
ISBN 13 : 9789088914348
Total Pages : 273 pages
Book Rating : 4.9/5 (143 download)
Download or read book Severe Cutaneous Adverse Drug Reactions written by Sylvia Helena Kardaun and published by . This book was released on 2012 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Neil H. Shear
Publisher : Springer
ISBN 13 : 9811314896
Total Pages : 307 pages
Book Rating : 4.8/5 (113 download)
Download or read book Advances in Diagnosis and Management of Cutaneous Adverse Drug Reactions written by Neil H. Shear and published by Springer. This book was released on 2018-10-19 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This resource guides prescribers, pharmacists, and regulators with an update on the recent expansion of basic and clinical knowledge that forms a framework for understanding cutaneous reactions. This understanding will lead, in turn, to better outcomes and decisions in treatment and management, both in the clinic and in the life cycle of drug development. The skin is a common target for adverse drug events and even mild rashes can be part of life-threatening syndromes. Patients and practitioners often face important decisions about therapy after a drug eruption, including treatment, cross-reactivity with future pharmaceuticals, genetic considerations and dealing with long-term sequelae after a reaction. An international team of experts and leaders in the field share their story and insights into the scientific details and relevant clinical context.
Author : Tannvir Jaffar Bandjee
Publisher :
ISBN 13 :
Total Pages : 38 pages
Book Rating : 4.:/5 (1 download)
Download or read book Value of Gradual Drug Re-challenges for Less Suspected Drugs in Severe Cutaneous Drug Reactions written by Tannvir Jaffar Bandjee and published by . This book was released on 2016 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt: BACKGROUND : Severe Cutaneous Drug Reactions (SCARs) can be life threatening and drug rechallenges are forbidden. Causality assessment criteria and patch tests help to identify culprit drugs. Yet, there is no recommendation about how to deal with the less suspected drugs, frequently stopped at the occurrence of SCARs, especially when they are essential therapeutics. METHODS : This was a retrospective unicenter study of practice, concerning drug reaction with eosinophilia and systemic symptoms (DRESS), acute generalised exanthematous pustulosis (AGEP) and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN). All consecutive patients who underwent a drug controlled gradual rechallenge between 2003 and 2016 were included. All the re-challenges were done after a medical concertation meeting, after consulting the prescribing physician. With the patient agreement, absolutely necessary drugs but with a low estimated responsibility in inducing the SCARs were re-administered step by step, at the rate of one dose each 7 to 10 days, from 10-5 of the daily dose to the full dose, with clinical and biological controls. RESULTS : Forty-one patients (80.5% DRESS, 4.9% AGEP, 14.6% SJS/TEN) underwent 105 gradual challenges. We observed 11 relapses for 9 patients, in 6 provocation tests and 5 substitution tests. All were non-severe reactions except one with a moderate reactivation of DRESS (pruriginous generalized exanthema, dyspnea, hypereosinophilia, liver cytolysis) 24 hours after the full dose, during an oral provocation test to rifampicin, for a DRESS caused by Vancomycin. CONCLUSIONS : Controlled gradual drug re-challenge, performed with great caution, in competent centres, is a safe method to test less suspected drug in order to identify well-tolerated essential therapeutics in SCARs.
Author : Andreas J. Bircher
Publisher : Springer Nature
ISBN 13 : 3030827437
Total Pages : 346 pages
Book Rating : 4.0/5 (38 download)
Download or read book Cutaneous Drug Hypersensitivity written by Andreas J. Bircher and published by Springer Nature. This book was released on 2022-07-09 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers all aspects of hypersensitivity to drugs, providing practical information for non-specialist physicians as well as addressing issues of interest to practitioners in different specialties and presenting the expert knowledge required by specialist allergists and immunologists. The opening, general section discusses basics such as clinical manifestations, histopathology, mechanisms, risk factors, drug hypersensitivity in particular populations, and the full range of diagnostic methods. The second part of the book provides concise information on the most important drug classes and guides the reader on how to proceed when patients present with a suspected reaction. For each drug class, the current level of evidence for use of the different diagnostic tools, including skin tests, provocation tests, and in vitro tests, is clarified, and management options, outlined. The inclusion of helpful tables and algorithms is designed to aid in decision making. Drug hypersensitivity is among the more complex allergological issues, and this book will meet the needs of general practitioners, internists, and specialists.
Author : Kirsti Kauppinen
Publisher : CRC-Press
ISBN 13 : 9780849383762
Total Pages : 178 pages
Book Rating : 4.3/5 (837 download)
Download or read book Skin Reactions to Drugs written by Kirsti Kauppinen and published by CRC-Press. This book was released on 1998-06-01 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasising the mechanisms and clinical and laboratory proof of a cause-and-effect relationship between drugs and adverse reactions, this book discusses the technique of drug challenge, which has been extensively developed in Finland, but not commonly practiced in the rest of the world. 12 of the most common drug eruptions are described both clinically and histologically. It features a chapter on systemic contact dermatitis and also addresses cutaneous adverse drug reactions that appear in HIV-infected patients. 40 full-color photographs provide vivid examples of the reactions being discussed. A highly practical resource for practicing physicians and other health care workers.
Author : Lars E. French
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805599706
Total Pages : 255 pages
Book Rating : 4.8/5 (55 download)
Download or read book Adverse Cutaneous Drug Eruptions written by Lars E. French and published by Karger Medical and Scientific Publishers. This book was released on 2012 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: An indispensable tool for understanding, diagnosing and managing this common clinical problem The skin is one of the most frequently involved organs in adverse drug reactions. Occurring with an incidence of 1-5% for certain types of drugs, cutaneous drug eruptions are mostly benign in nature, and comprise the maculopapular type of eruption and urticaria. However, about one third of them require hospital treatment, leading to a considerable burden for the health care system. In this book, a selected group of experts provide an up-to-date, condensed and clinically relevant overview of the field of cutaneous drug eruptions, ranging from epidemiology and genetic predisposition to available therapeutic measures, including rapid drug desensitization. Reflecting the great progress made in recent years in this field, this publication will be a useful tool for a better understanding, diagnosis and management of cutaneous drug eruptions, not only for general physicians, dermatologists and clinical allergologists, but also for nurses and scientists.
Author : Anne Lee
Publisher : Pharmaceutical Press
ISBN 13 : 9780853696018
Total Pages : 504 pages
Book Rating : 4.6/5 (96 download)
Download or read book Adverse Drug Reactions written by Anne Lee and published by Pharmaceutical Press. This book was released on 2006 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adverse reactions to medicines continue to present a burden on healthcare, causing considerable morbidity and mortality. Aswell as knowing about the benefits of medicines, healthcare professionals need to understand the problem of adverse drugreactions and be aware of how they can be prevented and managed. This essential and practical guide has been extensively revised and updated to include three new chapters on adverse effectsof drugs in pregnancy, pharmacogenetics, and side effects and patients. Case studies are provided with each chapter.
Author : O. L. Wade
Publisher : Elsevier
ISBN 13 : 1483141772
Total Pages : 241 pages
Book Rating : 4.4/5 (831 download)
Download or read book Adverse Reactions to Drugs written by O. L. Wade and published by Elsevier. This book was released on 2013-10-22 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adverse Reactions to Drugs, Second Edition focuses on the problems posed by the adverse responses to drugs, as well as drug interactions, dosage, and drug metabolism. The publication first tackles adverse reactions and factors which predispose to adverse drug reactions. Topics include dose adjustment, overdose, renal failure, cumulation, side effects, drug allergy, cumulative overdose, and delayed effects. The text then ponders on drug interactions, including renal excretion, drug metabolism, mutual toxicity, and interactions affecting transport to site of action. The manuscript examines adverse reactions in dental practice, drugs used in pregnancy, the neonate, and lactation, and problems for the pharmaceutical industry before marketing a new drug. Discussions focus on ethical problems of drug studies in man, pregnancy, hemorrhage, oxygen toxicity, chloramphenicol, drugs and lactation, drugs used in dental practice, and local anesthetics. The book then elaborates on monitoring adverse reactions to drugs and the therapeutic audit and drug regulatory bodies and their problems. The publication is a valuable source of data for doctors and dentists wanting to focus on research on the adverse reaction to drugs.
Author : David Khan
Publisher : Elsevier Health Sciences
ISBN 13 : 0323497071
Total Pages : 250 pages
Book Rating : 4.3/5 (234 download)
Download or read book Drug Allergy Testing written by David Khan and published by Elsevier Health Sciences. This book was released on 2017-07-05 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a focus on improving diagnosis and treatment, Drug Allergy Testing is your new go-to resource for understanding various drug allergies and testing methods, the epidemiology of and economic impact of drug allergies, and new drug and allergy developments. Features a wealth of up-to-date information for allergists, immunologists, and primary care physicians who diagnose and treat patients with drug allergies and hypersensitivity. Covers the basics of drug allergy evaluation and management as well as specific drugs including antibiotics, ASA/NSAIDs, chemotherapeutic agents and monoclonal antibodies.
Author : Rajesh Verma
Publisher : CRC Press
ISBN 13 : 135116502X
Total Pages : 1296 pages
Book Rating : 4.3/5 (511 download)
Download or read book Dermatological Emergencies written by Rajesh Verma and published by CRC Press. This book was released on 2019-05-20 with total page 1296 pages. Available in PDF, EPUB and Kindle. Book excerpt: ‘Dermatological Emergencies’ aims to cover aspects of situations and their management when they present in a Dermatology setup. This includes severe drug reactions, bullous disorders, erythroderma, infections, vasculitis and systemic emergencies presenting with skin signs. This book guides the reader to recognize such emergencies, helps to approach the initial phase of management, identifies the investigations, thus leading to a holistic management of the scene. Case scenarios are used in all chapters with logical flow of text, flowcharts, algorithms and representative clinical and laboratory images for better understanding of the readers. Key Features Details all dermatological emergencies Discusses manifestation of these emergencies with unique algorithms and flowcharts Examines case scenarios for first-hand experience Consists of Do's and Don'ts for effective management of cases Uses high quality clinical images for clarity
Author : Sandra Benavides
Publisher :
ISBN 13 : 9781932658897
Total Pages : 909 pages
Book Rating : 4.6/5 (588 download)
Download or read book Pediatric Pharmacotherapy written by Sandra Benavides and published by . This book was released on 2012 with total page 909 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Stephen Breathnach
Publisher : Wiley-Blackwell
ISBN 13 : 9780632033492
Total Pages : 408 pages
Book Rating : 4.0/5 (334 download)
Download or read book Adverse Drug Reactions and the Skin written by Stephen Breathnach and published by Wiley-Blackwell. This book was released on 1992-11-10 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adverse Drug Reactions and the Skin is a thoroughly modern and comprehensive text/atlas covering the side effects to the skin, from medications, and the dermatological and other internal adverse manifestations of medications used by dermatologists. Illustrated in full color, this major new work will enjoy wide use across a broad cross-section of the medical profession. This volume is divided into three major sections. The first deals with the incidence and mechanisms of drug adverse reactions. The second section discusses reaction patterns that are recognized as characteristic of cutaneous drug reactions to particular medications. The reaction patterns are fully discussed and the text is fully supported by wide use of full-color illustrations. Lists of the drugs most commonly implicated in the causation of these reactions are also included. The final section includes the drugs reported to have caused skin side-effects, in a systematic listing by therapeutic groups. This listing includes dermatological preparations. Thus, the reader is able to research information on skin changes potentially caused by a given drug, and also to determine which drugs cause a given clinical reaction pattern.
Author : John C. Hall
Publisher : Springer
ISBN 13 : 1447167295
Total Pages : 456 pages
Book Rating : 4.4/5 (471 download)
Download or read book Cutaneous Drug Eruptions written by John C. Hall and published by Springer. This book was released on 2015-08-21 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The burden of cutaneous drug reactions is significant, in both outpatient and inpatient settings, and can result in morbidity and even mortality. This book is unique in its approach to this problem. This text is divided into basic principles, common drug reactions, skin conditions mimicked by drug reactions, drug reactions to the skin appendages, life-threatening drug reactions, less common drug reactions, and special groupings of drug reactions. For the clinician, the skin can only morphologically react in to many limited ways. This is also true for the pathologist. Combining these two forever linked specialties is a synergistic paradigm that greatly enhances diagnosis, and ultimately therapy, for these pernicious conditions. Drug reactions in the skin remain a common complication of therapy. True incidences of drug reactions are not available. For general discussion, the rule of 3% can be applied with reasonable assuredness. Approximately 3% of all hospitalized patients develop an adverse cutaneous drug reaction. Approximately 3% of these reactions are considered severe. Outpatient data is even more obscure, but at least 3% of dermatology clinic outpatient visits are due to a drug reaction. Cutaneous drug reactions compromise approximately 3% of all drug reactions. Even more challenging is the fact that the most vulnerable populations to drug reactions are increasing and include the elderly patients on prolonged drug therapy, and patients that use multiple drugs at the same time.
Author : Ranthilaka R. Ranawaka
Publisher : Springer Nature
ISBN 13 : 9811554838
Total Pages : 1048 pages
Book Rating : 4.8/5 (115 download)
Download or read book Atlas of Dermatoses in Pigmented Skin written by Ranthilaka R. Ranawaka and published by Springer Nature. This book was released on 2020-12-23 with total page 1048 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the representation of dermatological diseases in pigmented skin, fills an important gap in the literature, and facilitates better dermatological diagnosis when dealing with patients of various ethnicities. It discusses over 400 diseases and their representations with the help of over 2000 high-quality images and illustrations. This book elaborates on each single disease using easy-to-follow schematics and a focused approach to facilitate reader learning. Pursuing a comprehensive, the book covers not only common skin diseases such as psoriasis, lichen planus, eczema, erythrasma, cutaneous tuberculosis, leprosy, leishmaniasis and oral submucous fibrosis, but also rare tropical diseases such as sporotrichosis, mycetoma, rhinosporodiosis, lobomycosis, mucormycosis and subcutaneous zygomycosis. It also addresses aesthetic concerns by covering hypopigmented and hyperpigmented disorders in pigmented skin such as guttate hypomelanosis, vitiligo, progressive macular hypomelanosis, chemical or physical induced depigmentation, melasma, sebo-melanosis, lichen and macular amyloidosis. Offering comprehensive coverage of dermatological disorders and diseases in pigmented skin, the book is a must-have resource for dermatology trainees and practitioners who treat or care for pigmented skin patients.
Author : Heng Leong Chan
Publisher :
ISBN 13 : 9789814045513
Total Pages : 140 pages
Book Rating : 4.0/5 (455 download)
Download or read book Cutaneous Adverse Drug Reactions written by Heng Leong Chan and published by . This book was released on 2000 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Amanda Oakley
Publisher : Scion Publishing Ltd
ISBN 13 : 1911510118
Total Pages : 438 pages
Book Rating : 4.9/5 (115 download)
Download or read book Dermatology Made Easy written by Amanda Oakley and published by Scion Publishing Ltd. This book was released on 2017-05-06 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise overview of the common dermatological conditions most likely to present in general medicine From reviews: "... a perfect solution to the constant struggle that dermatology diagnosis presents to primary care physicians and other providers... This well-formatted book covers a vast array of topics ranging from common to rare skin disorders. The pictures are immensely helpful in the understanding of various skin rashes...." Fam Med 2019;51(5):451–452. “... easy to read and informative. One cannot emphasise enough the quality and comprehensive nature of the photographic content.... As someone who was interested in dermatology even as a medical student my only regret is that this book was not around when I was a student as it would have very adequately guided me into my beloved subspecialty.” Ulster Med J 2017;86(3):1–1. “The introduction outlines dermatological conditions by symptom, morphology and body site, providing an excellent index prior to delving into greater detail in the following chapters. The logical approach and level of detail make this text perfect for medical students, interns/residents, primary care physicians and other specialists who wish to quickly identify differential diagnoses or refresh their knowledge of dermatological conditions.” A Lecturer in Dermatology Dermatology Made Easy is based on the hugely popular DermNet New Zealand website and is designed to help GPs, medical students and dermatologists diagnose skin conditions with confidence. The book starts by providing a series of comprehensive tables, complete with over 500 thumbnail photos, to aid diagnosis according to symptoms, morphology, or body site. Once you have narrowed down the diagnosis, cross-references then guide you to more detailed descriptions, and another 700 photographs, covering: common infections inflammatory rashes non-inflammatory conditions skin lesions Every section provides consistent information on the disorder: who gets it and what causes it? what are the clinical features and does it cause any complications? how do you diagnose it? how do you treat it and how long does it take to resolve? The book concludes with a comprehensive section on further investigations and treatment options. Dermatology Made Easy combines the essential focus of the Made Easy book series with the authority and knowledge base of DermNet New Zealand’s unparalleled resources. Printed in full colour throughout.
