Drug Delivery Systems For Cardiovascular Diseases

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Drug Delivery Systems for Cardiovascular Diseases

Author : Shobha Rani R Hiremath
Publisher : CRC Press
ISBN 13 : 9781439852750
Total Pages : 304 pages
Book Rating : 4.8/5 (527 download)

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Book Synopsis Drug Delivery Systems for Cardiovascular Diseases by : Shobha Rani R Hiremath

Download or read book Drug Delivery Systems for Cardiovascular Diseases written by Shobha Rani R Hiremath and published by CRC Press. This book was released on 2014-01-15 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each year, more Americans die from heart diseases than cancer, yet there is no single source that combines information about cardiovascular diseases with disease-specific drug delivery systems. This book provides an overview of existing techniques, ongoing research, and novel approaches and concepts in the treatment of cardiovascular diseases by means of novel drug delivery systems. The text covers anatomy, biochemistry, pathophysiology, and pharmacotherapy. It also addresses problems associated with therapy, reasons for non-compliance, formulation and evaluation of drug delivery systems, as well as regulatory aspects of cardiovascular drug discovery systems.

Advanced Drug Delivery

Author : Ashim Mitra
Publisher : John Wiley & Sons
ISBN 13 : 1118662849
Total Pages : 844 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Advanced Drug Delivery by : Ashim Mitra

Download or read book Advanced Drug Delivery written by Ashim Mitra and published by John Wiley & Sons. This book was released on 2013-08-26 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatment of a broad range of human diseases. Advanced Drug Delivery features contributions from an international team of pharmaceutical scientists. Chapters reflect a thorough review and analysis of the literature as well as the authors' firsthand experience developing drug delivery systems. The book is divided into four parts: Part I, Introduction and Basics of Advanced Drug Delivery, explores physiological barriers, stability, transporters, and biomaterials in drug delivery Part II, Strategies for Advanced Drug Delivery, offers tested and proven strategies for advanced delivery of both small molecules and macromolecules Part III, Translational Research of Advanced Drug Delivery, focuses on regulatory considerations and translational applications of advanced drug delivery systems for the treatment of cardiovascular diseases, cancer, sexually transmitted diseases, ophthalmic diseases, and brain diseases Part IV, Future Applications of Advanced Drug Delivery in Emerging Research Areas, examines stem cell research, cell-based therapeutics, tissue engineering, and molecular imaging Each chapter provides objectives and assessment questions to help readers grasp key concepts and assess their knowledge as they progress through the book. Advanced Drug Delivery is recommended for graduates and upper-level undergraduates in the pharmaceutical sciences who need a solid foundation in the basics. It is also recommended for pharmaceutical professionals who want to take advantage of new and emerging applications in advanced drug delivery systems.

Antibody-Mediated Drug Delivery Systems

Author : Yashwant V. Pathak
Publisher : John Wiley & Sons
ISBN 13 : 0470612819
Total Pages : 542 pages
Book Rating : 4.4/5 (76 download)

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Book Synopsis Antibody-Mediated Drug Delivery Systems by : Yashwant V. Pathak

Download or read book Antibody-Mediated Drug Delivery Systems written by Yashwant V. Pathak and published by John Wiley & Sons. This book was released on 2012-05-15 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers various aspects of antibody mediated drug delivery systems – theoretical aspects, processing, viral and non-viral vectors, and fields where these systems find and /or are being evaluated for applications as therapeutics and diagnostic treatment. Chapters discuss actual applications of techniques used for formulation and characterization. Applications areas include cancer, pulmonary, ocular diseases; brain drug delivery; and vaccine delivery. The contributing authors represent over 10 different countries, covering recent developments happening around the globe.

Engineering Improvements for Epicardial Drug Delivery Systems

Author : Shahrin Islam
Publisher :
ISBN 13 :
Total Pages : 80 pages
Book Rating : 4.:/5 (113 download)

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Book Synopsis Engineering Improvements for Epicardial Drug Delivery Systems by : Shahrin Islam

Download or read book Engineering Improvements for Epicardial Drug Delivery Systems written by Shahrin Islam and published by . This book was released on 2019 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular diseases continue have a large disease burden despite advancements in technology, therapeutic modalities, and prevention efforts. For various cardiovascular pathologies, epicardial drug delivery systems have shown promise. Our group has developed a replenishable epicardial drug delivery device called Therepi that allows for repeat administrations of therapeutics without necessitating multiple invasive surgeries. The purpose of this thesis is to improve upon the Therepi device and utilize the platform to study the effects of specific therapeutics on cardiac function in a preclinical small animal myocardial infarction (MI) model. I first show that the fibrous capsule that forms around the polycarbonate membrane interface of the first iteration Therepi device post-implantation can impede transport of therapeutics from the device to the heart. Then, I utilize a modified version of Therepi without the polycarbonate membrane to study the effects of repeat administrations of FSTL1, a promising protein with great therapeutic potential, on cardiac function post-MI. Results from this study indicate that removal of the polycarbonate membrane reduces the formation of a fibrous capsule and that repeat administrations of FSTL1 improve cardiac function after MI. Following this, I utilize a computational macroscale model of Therepi to study the effect of important design parameters such as loading conditions, biomaterial geometry and orientation relative to the cardiac fibers on drug delivery to the myocardium. The simulations highlight the significance of the cardiac fiber anisotropy as a crucial factor in governing drug distribution on the epicardial surface and limiting factor for penetration into the myocardium. The multiscale model can be useful for rapid iteration of different device concepts and determination which designs for epicardial drug delivery may be optimal and most promising for the ultimate therapeutic goal. In the future, the findings from this thesis will be further investigated to develop an improved version of Therepi that allows for better device-tissue adhesion, conformability, and transport. The effects of repeat administrations of FSTL1 from the Therepi device will be elucidated further to mechanistically understand how cardiac function is improved through this strategy.

Application of Biomaterials in the Treatment of Cardiovascular Diseases

Author : Yi-Da Tang
Publisher : Springer
ISBN 13 : 9789811977114
Total Pages : 0 pages
Book Rating : 4.9/5 (771 download)

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Book Synopsis Application of Biomaterials in the Treatment of Cardiovascular Diseases by : Yi-Da Tang

Download or read book Application of Biomaterials in the Treatment of Cardiovascular Diseases written by Yi-Da Tang and published by Springer. This book was released on 2023-08-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the recent advancements for biomaterials in the field of cardiovascular disease, including drug delivery system (gene, protein, drug), implant interventional instrument (heart valve, heart blocker, stent, artificial blood vessel, patch, artificial heart, cardiac pacemaker, etc.) have been innovated and applied to the clinical uses to treatment of cardiovascular disease. Through the summary of this book, readers will have comprehensive and advanced understanding of the application of biomaterials in the field of cardiovascular disease.

Advances in Nanotechnology-Based Drug Delivery Systems

Author : Anupam Das Talukdar
Publisher : Elsevier
ISBN 13 : 0323904149
Total Pages : 672 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Advances in Nanotechnology-Based Drug Delivery Systems by : Anupam Das Talukdar

Download or read book Advances in Nanotechnology-Based Drug Delivery Systems written by Anupam Das Talukdar and published by Elsevier. This book was released on 2022-06-06 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Nanotechnology-Based Drug Delivery Systems covers the core concepts and latest research regarding the use of nanoscale materials for the development and application of drug delivery systems. The book introduces the reader to nanotechnology in drug delivery, covering the synthesis, encapsulation techniques, characterization and key properties of nanoscale drug delivery systems. Later chapters review the broad range of target applications, including site-specific delivery of drugs for cardiovascular disease, cancer, bacterial infection, bone regeneration. and much more. This book helps translate advanced research into a clinical setting, analyzing the toxicity and health and safety challenges associated with utilizing nanotechnology in biomedicine. This will be a useful reference for those interested in nano-sized drug delivery in biomedicine, including academics and researchers in materials science, biomedical engineering, pharmaceutical science and related disciplines. Provides a clear introduction to nanotechnology in drug delivery, covering key principles, synthesis, characterization and unique properties of nanoscale materials for drug delivery systems“/li> Discusses preclinical, clinical and patented nano-drug delivery systems, enabling the reader to grasp the current state-of-the-art and market Covers a broad range of targets for nanoscale drug delivery systems, such as in neurological disorders, oral disease, renal disease, cancer, skin protection, and much more

Nanomedicine and Cancer

Author : Rajaventhan Srirajaskanthan
Publisher : CRC Press
ISBN 13 : 1578087279
Total Pages : 462 pages
Book Rating : 4.5/5 (78 download)

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Book Synopsis Nanomedicine and Cancer by : Rajaventhan Srirajaskanthan

Download or read book Nanomedicine and Cancer written by Rajaventhan Srirajaskanthan and published by CRC Press. This book was released on 2011-12-20 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nanosciences are a rapidly expanding field of research with a wide applicability to all areas of health. They encompass a variety of technologies ranging from particles to networks and nanostructures. This book focuses on the application of nanomedicine and nanotechnology to cancer. It introduces nanocarriers, nanorods, nanoprobes nanoplatforms, nanorings, nanotubes nanowires, nano-sensor arrays and a variety of methodological techniques. This is done within the framework of numerous cancer types. Contributors are all leading experts and are carrying out groundbreaking work. The book is essential reading for oncologists, research scientists, doctors, health care professionals, pathologists, biologists, biochemists, chemists and physicists as well as those interested in disease and nanosciences or cancer in general.

Molecular Interventions and Local Drug Delivery

Author : Elazer R. Edelman
Publisher : Bailliere Tindall Limited
ISBN 13 :
Total Pages : 520 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular Interventions and Local Drug Delivery by : Elazer R. Edelman

Download or read book Molecular Interventions and Local Drug Delivery written by Elazer R. Edelman and published by Bailliere Tindall Limited. This book was released on 1995 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant advances continue to be made in elucidating the cellular and molecular mechanisms of cardiovascular diseases. Recent technical innovations - in molecular therapies and local drug delivery - now permit clinicians to exploit information on pathophysiology in order to treat these conditions more effectively. In this significant new work, Elazer Edelman and Robert Levy bring together a team of authorities in the field, integrating basic and clinical research data with state-of-the-art engineering and technology, to give the cardiovascular physician a clear, readable and up-to-the-minute resource of invaluable information, in the first systematic and comprehensive review of this area.

Pulsatile Drug Delivery System

Author : Ashutosh Pareek
Publisher : LAP Lambert Academic Publishing
ISBN 13 : 9783844392104
Total Pages : 68 pages
Book Rating : 4.3/5 (921 download)

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Book Synopsis Pulsatile Drug Delivery System by : Ashutosh Pareek

Download or read book Pulsatile Drug Delivery System written by Ashutosh Pareek and published by LAP Lambert Academic Publishing. This book was released on 2011-04 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pulsatile Drug Delivery Systems are gaining a lot of interest as these systems deliver the drug at specific time as per the pathophysiological need of the disease, thus providing spatial and temporal delivery and increasing patient compliance. Diseases wherein such delivery systems are promising include asthma, peptic ulcer, cardiovascular diseases, arthritis, attention deficit syndrome in children, and hypercholesterolemia. This book will cover various approaches that have been developed to control drug delivery profile with different polymeric systems like time controlling, internal stimuli induced (temperature induced and chemical stimuli-induced), external induced (magnetic fields, ultrasound, electric fields and light stimulation) and Multiparticulate system. Special attention have been made towards recent advances, patents, future opportunity and major challenges regarding formulation of pulsatile drug delivery of oral dosage forms and are summarized and discussed.

Drug Delivery

Author : Yitzhak Rosen
Publisher : CRC Press
ISBN 13 : 1466565950
Total Pages : 602 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Drug Delivery by : Yitzhak Rosen

Download or read book Drug Delivery written by Yitzhak Rosen and published by CRC Press. This book was released on 2017-09-19 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrating the clinical and engineering aspects of drug delivery, this book offers a much needed comprehensive overview and patient-oriented approach for enhanced drug delivery optimization and advancement. Starting with an introduction to the subject and pharmacokinetics, it explores advances for such topics as oral, gastroretentive, intravitreal, and intrathecal drug delivery, as well as insulin delivery, gene delivery, and biomaterials-based delivery systems. It also describes drug delivery in cancer, cardiac, infectious diseases, airway diseases, and obstetrics and gynecology applications. Examining special clinical states requiring innovative drug delivery modifications, such as hypercoagulability often seen in pregnancy, cancer, and autoimmune diseases, the book also discusses methods for improved drug delivery in clinical settings using clinical end points, clinical trials, simulations, and other venues. It also describes the latest drug delivery advances involving nanomaterials, NEMS and MEMS devices, hydrogels, microencapsulation, lipids, stem cells, patches, and ultrasound. The book is rounded out by a chapter on the FDA regulatory and bioethical challenges involved in advancing drug delivery.

Applications of Biotechnology in Cardiovascular Therapeutics

Author : Kewal K. Jain
Publisher : Springer Science & Business Media
ISBN 13 : 1617792403
Total Pages : 376 pages
Book Rating : 4.6/5 (177 download)

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Book Synopsis Applications of Biotechnology in Cardiovascular Therapeutics by : Kewal K. Jain

Download or read book Applications of Biotechnology in Cardiovascular Therapeutics written by Kewal K. Jain and published by Springer Science & Business Media. This book was released on 2011-07-25 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: For physicians, surgeons, and scientists working on cardiovascular disorders, Applications of Biotechnology in Cardiovascular Therapeutics serves as an invaluable reference by collecting the essential writings of Dr. Kewal K. Jain on the topics of biotechnology as they relate to cardiovascular disease. This thorough volume includes such subjects as biotechnology and therapeutic delivery to the cardiovascular system, cell-selective targeted drug delivery, cell and gene therapies, including antisense and RNA interference, cutting-edge gene therapy approaches, as well as personalized cardiology as a way of integrating new technologies into the selection of the best possible treatment for an individual patient. Selected references from recent literature are collected for each chapter, and the text is supplemented by a variety of useful tables and figures. Comprehensive and up-to-date, Applications of Biotechnology in Cardiovascular Therapeutics will be tremendously useful for those working in life sciences and the pharmaceutical sciences, and the inclusion of some basics of cardiovascular diseases will greatly benefit nonmedical readers as well.

Drug Delivery Systems in Cardiovascular Therapeutics

Author : Pamela Bassett
Publisher :
ISBN 13 : 9781579361907
Total Pages : 303 pages
Book Rating : 4.3/5 (619 download)

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Book Synopsis Drug Delivery Systems in Cardiovascular Therapeutics by : Pamela Bassett

Download or read book Drug Delivery Systems in Cardiovascular Therapeutics written by Pamela Bassett and published by . This book was released on 2002-01-01 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines several key trends that are emerging in the treatment of cardiovascular diseases that will change the course of therapy substantially during the next decade.

Advanced Drug Delivery Systems in the Management of Cancer

Author : Kamal Dua
Publisher : Elsevier
ISBN 13 : 0323900798
Total Pages : 572 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Advanced Drug Delivery Systems in the Management of Cancer by : Kamal Dua

Download or read book Advanced Drug Delivery Systems in the Management of Cancer written by Kamal Dua and published by Elsevier. This book was released on 2021-06-24 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Drug Delivery Systems in the Management of Cancer discusses recent developments in nanomedicine and nano-based drug delivery systems used in the treatment of cancers affecting the blood, lungs, brain, and kidneys. The research presented in this book includes international collaborations in the area of novel drug delivery for the treatment of cancer. Cancer therapy remains one of the greatest challenges in modern medicine, as successful treatment requires the elimination of malignant cells that are closely related to normal cells within the body. Advanced drug delivery systems are carriers for a wide range of pharmacotherapies used in many applications, including cancer treatment. The use of such carrier systems in cancer treatment is growing rapidly as they help overcome the limitations associated with conventional drug delivery systems. Some of the conventional limitations that these advanced drug delivery systems help overcome include nonspecific targeting, systemic toxicity, poor oral bioavailability, reduced efficacy, and low therapeutic index. This book begins with a brief introduction to cancer biology. This is followed by an overview of the current landscape in pharmacotherapy for the cancer management. The need for advanced drug delivery systems in oncology and cancer treatment is established, and the systems that can be used for several specific cancers are discussed. Several chapters of the book are devoted to discussing the latest technologies and advances in nanotechnology. These include practical solutions on how to design a more effective nanocarrier for the drugs used in cancer therapeutics. Each chapter is written with the goal of informing readers about the latest advancements in drug delivery system technologies while reinforcing understanding through various detailed tables, figures, and illustrations. Advanced Drug Delivery Systems in the Management of Cancer is a valuable resource for anyone working in the fields of cancer biology and drug delivery, whether in academia, research, or industry. The book will be especially useful for researchers in drug formulation and drug delivery as well as for biological and translational researchers working in the field of cancer. Presents an overview of the recent perspectives and challenges within the management and diagnosis of cancer Provides insights into how advanced drug delivery systems can effectively be used in the management of a wide range of cancers Includes up-to-date information on diagnostic methods and treatment strategies using controlled drug delivery systems

Emerging Approaches in Novel Drug Delivery System

Author : Preeti Singh
Publisher :
ISBN 13 : 9789360091729
Total Pages : 0 pages
Book Rating : 4.0/5 (917 download)

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Book Synopsis Emerging Approaches in Novel Drug Delivery System by : Preeti Singh

Download or read book Emerging Approaches in Novel Drug Delivery System written by Preeti Singh and published by . This book was released on 2024-05-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drug Targeting and Stimuli Sensitive Drug Delivery Systems

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
ISBN 13 : 0128136901
Total Pages : 836 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Drug Targeting and Stimuli Sensitive Drug Delivery Systems by : Alexandru Mihai Grumezescu

Download or read book Drug Targeting and Stimuli Sensitive Drug Delivery Systems written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2018-05-21 with total page 836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Targeting and Stimuli Sensitive Drug Delivery Systems covers recent advances in the area of stimuli sensitive drug delivery systems, providing an up-to-date overview of the physical, chemical, biological and multistimuli-responsive nanosystems. In addition, the book presents an analysis of clinical status for different types of nanoplatforms. Written by an internationally diverse group of researchers, it is an important reference resource for both biomaterials scientists and those working in the pharmaceutical industry who are looking to help create more effective drug delivery systems. Shows how the use of nanomaterials can help target a drug to specific tissues and cells Explores the development of stimuli-responsive drug delivery systems Includes case studies to showcase how stimuli responsive nanosystems are used in a variety of therapies, including camptothecin delivery, diabetes and cancer therapy

Chronotherapeutics

Author : P. H. Redfern
Publisher : Pharmaceutical Press
ISBN 13 : 9780853694885
Total Pages : 456 pages
Book Rating : 4.6/5 (948 download)

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Book Synopsis Chronotherapeutics by : P. H. Redfern

Download or read book Chronotherapeutics written by P. H. Redfern and published by Pharmaceutical Press. This book was released on 2003 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: In nature, many physical processes are governed by the passage of time. The study of these processes - chronobiology - reveals rhythmic patterns which may be yearly, monthly, daily or more frequent. Novel drug delivery systems are currently being delivered that will release varying quantities of a drug at optimum times to coincide with these rhythmic patterns.Chronotherapeutics considers the pharmaceutical and therapeutic implications associated with biological clocks. The book presents a comprehensive discussion of specific diseases that are time dependent, and the drugs and new drug formulations that can be used as treatments.Written by leading international experts in the field, Chronotherapeutics provides up-to-date information on chronobiology for non-chronobiologists in pharmaceutical and medical sciences. Peter Redfern is Professor of Pharmacology at the University of Bath, UK.

Nanomedicinal Approaches Towards Cardiovascular Disease

Author : Fahima Dilnawaz
Publisher : Bentham Science Publishers
ISBN 13 : 9814998222
Total Pages : 176 pages
Book Rating : 4.8/5 (149 download)

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Book Synopsis Nanomedicinal Approaches Towards Cardiovascular Disease by : Fahima Dilnawaz

Download or read book Nanomedicinal Approaches Towards Cardiovascular Disease written by Fahima Dilnawaz and published by Bentham Science Publishers. This book was released on 2021-07-27 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomedicinal Approaches Towards Cardiovascular Disease summarizes information about nanotechnology that is used in the diagnosis and regenerative treatment of heart diseases. Chapters in this reference introduce the reader to the basics of cardiac nanomedicine and cardiac regeneration before moving to advanced topics such as nanomedicine in cardiovascular diagnosis, imaging and therapeutics. Key Features - 13 chapters that cover nanotechnological aspects of cardiovascular diseases, contributed by expert scholars - Simple, reader-friendly text suitable for readers of all academic levels - Covers introductory topics of nanomedicine regenerative medicine in cardiovascular disease, cardiovascular diagnosis and therapeutics - Covers advanced topics such as cardiovascular nanotheranositics, cardiac reprogramming, biomimetics, drug delivery systems and smart nanomaterials - Includes a chapter on ethical implications in cardiovascular nanomedicine - Includes bibliographic references for each chapter Nanomedicinal Approaches Towards Cardiovascular Disease is a simple. informative reference on cardiovascular nanomedicine for scholars, healthcare professionals and nanotechnology enthusiasts, alike, which provides holistic knowledge on the subject in a single volume.