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Dosimetry For Radiopharmaceutical Therapy
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Book Synopsis Dosimetry for Radiopharmaceutical Therapy by : IAEA
Download or read book Dosimetry for Radiopharmaceutical Therapy written by IAEA and published by International Atomic Energy Agency. This book was released on 2024-04-30 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this publication the basic principles of radiation physics, imaging and non-imaging instrumentation used, measurement of the administered activity, calibration procedures and methods for obtaining quantitative information on the biodistribution of the radioactive drug to be used with radioisotopes relevant to therapy are specified. It also describes methods for segmentation and registration of images acquired at different time points, strategies for fitting and integration of activity measurements over the time of treatment, absorbed dose calculations and derived dosimetric indexes with methods to estimate the overall uncertainty of different radionuclide therapies. The aim of this book is to fill the existing gaps in education and training of medical physicists on methods for patient-specific dosimetry. The overall objective of this book is to highlight the tools and methodologies to assure that radiopharmaceutical therapy is implemented through a dosimetry-guided individualized treatment approach.
Author :International Atomic Energy Agency Publisher :International Atomic Energy Agency ISBN 13 :9789201395238 Total Pages :0 pages Book Rating :4.3/5 (952 download)
Book Synopsis Dosimetry for Radiopharmaceutical Therapy by : International Atomic Energy Agency
Download or read book Dosimetry for Radiopharmaceutical Therapy written by International Atomic Energy Agency and published by International Atomic Energy Agency. This book was released on 2024-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this publication the basic principles of radiation physics, imaging and non-imaging instrumentation used, measurement of the administered activity, calibration procedures and methods for obtaining quantitative information on the biodistribution of the radioactive drug to be used with radioisotopes relevant to therapy are specified. It also describes methods for segmentation and registration of images acquired at different time points, strategies for fitting and integration of activity measurements over the time of treatment, absorbed dose calculations and derived dosimetric indexes with methods to estimate the overall uncertainty of different radionuclide therapies. The aim of this book is to fill the existing gaps in education and training of medical physicists on methods for patient-specific dosimetry. The overall objective of this book is to highlight the tools and methodologies to assure that radiopharmaceutical therapy is implemented through a dosimetry-guided individualized treatment approach.
Book Synopsis MIRD: Radionuclide Data and Decay Schemes by : Keith F. Eckerman
Download or read book MIRD: Radionuclide Data and Decay Schemes written by Keith F. Eckerman and published by Snmmi. This book was released on 2007 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Targeted Radionuclide Therapy by : Tod W. Speer
Download or read book Targeted Radionuclide Therapy written by Tod W. Speer and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioimmunotherapy, also known as systemic targeted radiation therapy, uses antibodies, antibody fragments, or compounds as carriers to guide radiation to the targets. It is a topic rapidly increasing in importance and success in treatment of cancer patients. This book represents a comprehensive amalgamation of the radiation physics, chemistry, radiobiology, tumor models, and clinical data for targeted radionuclide therapy. It outlines the current challenges and provides a glimpse at future directions. With significant advances in cell biology and molecular engineering, many targeting constructs are now available that will safely deliver these highly cytotoxic radionuclides in a targeted fashion. A companion website includes the full text and an image bank.
Book Synopsis Radiopharmaceuticals for Therapy by : F. F. (Russ) Knapp
Download or read book Radiopharmaceuticals for Therapy written by F. F. (Russ) Knapp and published by Springer. This book was released on 2016-01-20 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides detailed information on therapeutic radiopharmaceuticals and discusses emerging technologies which have potential for broad clinical implementation. Recent advances in molecular biology, radiopharmaceutical chemistry and radioisotope production have stimulated a new era for the use of radiopharmaceuticals for targeted radionuclide therapy (TRT). Emerging clinical trials include use of peptides and monoclonal antibodies radiolabeled with therapeutic radionuclides for cancer therapy. In addition, small molecules are used for the treatment of chronic diseases such as metastatic bone pain palliation and radiation synovectomy of inflammatory joints. In the interventional arena, therapy of primary and metastatic liver cancer and arterial restenosis following angioplasty of both the coronary and peripheral arteries are being explored. Reactor and accelerator production of therapeutic radioisotopes is also integrated into these discussions. The development and use of radiopharmaceutical targeting characteristics required for treatment of specific disease processes and how these are implemented for radiopharmaceutical design strategies are also described. Radiopharmaceuticals for Therapy will benefit audiences in nuclear medicine and radionuclide therapy and will thus prove an invaluable source of up-to-date information for students, radiopharmaceutical scientists and professionals working in the radiopharmacy and nuclear medicine specialties.
Book Synopsis Radiopharmaceutical Therapy and Dosimetry by : Robert F. Hobbs
Download or read book Radiopharmaceutical Therapy and Dosimetry written by Robert F. Hobbs and published by . This book was released on 2023-06-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiopharmaceutical Therapy (RPT) is fast becoming a mainstream modality with the development and approval of new emitters and conjugates. Professionals from the fields of radiation oncology and nuclear medicine are expressing interest in learning the fundamentals of implementing radiopharmaceutical therapy in their clinics. While multiple efforts are underway to add more radiopharmaceutical-specific material to training programs, retrospective training of medical physicists in this discipline is a gigantic unmet need. To meet this need, the AAPM held a comprehensive summer school program in Minneapolis in 2023 on radiopharmaceutical therapy and dosimetry.These summer school proceedings cover all aspects of RPT, from a comprehensive list of currently approved radiopharmaceuticals and their uses to post-treatment patient release criteria. The program placed a special emphasis on the state of the art in voxelized and organ-level dosimetry for RPT. Presenters gave a description of how RPT could adopt patient-specific, dosimetry-based treatment planning in the near future instead of relying upon a one-size-fits-all dosing approach.Many of the world's leading authorities in RPT have contributed chapters for this book. Their insights will be referred to and valued for years to come.
Book Synopsis Nuclear Medicine Radiation Dosimetry by : Brian J McParland
Download or read book Nuclear Medicine Radiation Dosimetry written by Brian J McParland and published by Springer Science & Business Media. This book was released on 2010-07-03 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complexities of the requirements for accurate radiation dosimetry evaluation in both diagnostic and therapeutic nuclear medicine (including PET) have grown over the past decade. This is due primarily to four factors: Growing consideration of accurate patient-specific treatment planning for radionuclide therapy as a means of improving the therapeutic benefit, development of more realistic anthropomorphic phantoms and their use in estimating radiation transport and dosimetry in patients, Design and use of advanced Monte Carlo algorithms in calculating the above-mentioned radiation transport and dosimetry which require the user to have a thorough understanding of the theoretical principles used in such algorithms, their appropriateness and their limitations, increasing regulatory scrutiny of the radiation dose burden borne by nuclear medicine patients in the clinic and in the development of new radiopharmaceuticals, thus requiring more accurate and robust dosimetry evaluations. An element common to all four factors is the need for precise radiation dosimetry in nuclear medicine, which is fundamental to the therapeutic success of a patient undergoing radionuclide therapy and to the safety of the patients undergoing diagnostic nuclear medicine and PET procedures. As the complexity of internal radiation dosimetry applied to diagnostic and therapeutic nuclear medicine increases, this book will provide the theoretical foundations for: enabling the practising nuclear medicine physicist to understand the dosimetry calculations being used and their limitations, allowing the research nuclear medicine physicist to critically examine the internal radiation dosimetry algorithms available and under development; and providing the developers of Monte Carlo codes for the transport of radiation resulting from internal radioactive sources with the only comprehensive and definitive.
Book Synopsis Advances in Dosimetry and New Trends in Radiopharmaceuticals by : Elisabeth Eppard
Download or read book Advances in Dosimetry and New Trends in Radiopharmaceuticals written by Elisabeth Eppard and published by BoD – Books on Demand. This book was released on 2024-04-03 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Dosimetry and New Trends in Radiopharmaceuticals is organized into two sections. The first section discusses different dosimetry methods that are used in radiotherapy systems, such as image-guided radiotherapy (IGRT). The second section examines the types and quality of radiochemical applications in nuclear medicine and their radiation dosimetry analysis.
Book Synopsis Third International Radiopharmaceutical Dosimetry Symposium by : Evelyn E. Watson
Download or read book Third International Radiopharmaceutical Dosimetry Symposium written by Evelyn E. Watson and published by . This book was released on 1981 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book MIRD written by and published by . This book was released on 2015 with total page 67 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Practice of Internal Dosimetry in Nuclear Medicine by : Michael G. Stabin
Download or read book The Practice of Internal Dosimetry in Nuclear Medicine written by Michael G. Stabin and published by CRC Press. This book was released on 2016-10-14 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by one of the world's leading experts in the field of nuclear medicine dosimetry, this text describes in detail the use of internal dose calculations in the practice of nuclear medicine. While radiation therapy with external sources of radiation always employs calculations of dose to optimize therapy for each patient, this is not routinely conducted in nuclear medicine therapy. As the trend towards an increasing role of dosimetry in therapy planning increases, this book reviews the available methods and technologies available to make this a more common practice. The book begins by covering the mathematical fundamentals of internal dose calculations, and uses sample calculations to demonstrate key principles. The book then moves forward to describe anthropomorphic models, dosimetric models, and types and uses of diagnostic and therapeutic radiopharmaceuticals. The depth of coverage makes it useful reference and guide for researchers performing dose calculations and for physicians considering incorporating dose calculations into the treatment of their cancer patients.
Book Synopsis Advancing Nuclear Medicine Through Innovation by : National Research Council
Download or read book Advancing Nuclear Medicine Through Innovation written by National Research Council and published by National Academies Press. This book was released on 2007-09-11 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.
Book Synopsis Locoregional Radionuclide Cancer Therapy by : Franklin C.L. Wong
Download or read book Locoregional Radionuclide Cancer Therapy written by Franklin C.L. Wong and published by Springer Nature. This book was released on 2020-12-08 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews locoregional radionuclide cancer therapies (LRCT). Proving an increasingly viable alternative to radiotherapy, radionuclide therapy includes a diversity of choices of well characterized biochemical and physiologic target molecules. The delivery and retention of radionuclides may be monitored by advanced imaging for exact tissue localization and for real-time dosimetry to enable personalized precision medicine. Radiopharmaceuticals in human cancer therapies are typically delivered in systemic routes but can also be designed for locoregional routes to harness pharmacokinetic advantages of higher payload and lower systemic toxicities. This book explores the latest advancements and clinical considerations of the locoregional approach. Throughout the chapters, the clinical and scientific bases of cancer treatment and the locoregional use of radionculides are explored. Mathematical models of radiation dosimetry of locoregional radionculdies on tissues are studied using common models for multiple commercially available radionuclides. Rodent and canine tumor models of LRCT are compared for selected radionuclides and radiopharmaceuticals. The practical aspects of radiopharmaceuticals production, marketing, transport, as well as radiation protection are reviewed. Finally, the combination of LRCT with immunotherapy and other cancer therapies and prospective future use of LRCT are discussed. This is a guide for practicing nuclear physicians, interventional radiologists, radiation oncologists, radiation scientists, veterinarians and oncologists to expand their knowledge base and to prepare for designing locoregional radionuclide cancer therapies in animals and in humans.
Book Synopsis Therapeutic Nuclear Medicine by : Richard P. Baum
Download or read book Therapeutic Nuclear Medicine written by Richard P. Baum and published by Springer. This book was released on 2014-08-16 with total page 922 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. This up-to-date, comprehensive book, written by world-renowned experts, discusses the basic principles of radionuclide therapy, explores in detail the available treatments, explains the regulatory requirements, and examines likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the role of the therapeutic nuclear physician in coordinating a diverse multidisciplinary team, which is central to the safe provision of treatment.
Book Synopsis Radiopharmaceutical Therapy and Dosimetry by : Robert Hobbs
Download or read book Radiopharmaceutical Therapy and Dosimetry written by Robert Hobbs and published by . This book was released on 2023-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Physics for Clinical Oncology by : Amen Sibtain
Download or read book Physics for Clinical Oncology written by Amen Sibtain and published by Oxford University Press. This book was released on 2022-11-24 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiotherapy remains a major non-surgical treatment modality for malignant disease, and an understanding of how this treatment works is essential in ensuring optimum practice. Trainees in oncology learn about ionising radiation, but to understand it fully they must also understand the physics relevant to its use in therapy. This book is written specifically for the oncology and radiation team, supporting clinical oncologists in their understanding of the science which underpins radiotherapy. It begins with basic concepts and then explores the principles and practice of physics as it relates to radiotherapy, including discussion of specific types of therapy. Written by authors chosen for their expertise in in their respective fields, and aligned to the Royal College of Radiologists FRCR Curriculum in Oncology, this volume will provide an excellent source of information for trainee and practicing oncologists, and wider radiotherapy teams. This second edition has been fully updated to reflect advances in technology and the increased complexity in modern radiotherapy, including two new chapters on imaging and a new brachytherapy chapter.
Author :International Atomic Energy Agency Publisher :International Atomic Energy Agency ISBN 13 :9789201040190 Total Pages : pages Book Rating :4.0/5 (41 download)
Book Synopsis Nuclear Medicine Resources Manual by : International Atomic Energy Agency
Download or read book Nuclear Medicine Resources Manual written by International Atomic Energy Agency and published by International Atomic Energy Agency. This book was released on 2021-03-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical imaging is crucial in a variety of medical settings and at all levels of health care. In public health and preventive medicine as well as in both curative and palliative care, effective decisions depend on correct diagnoses. This edition addresses the most current needs and offers guidance on clinical practice, radiation safety and patient protection, human resource development and training required for the overall practice of nuclear medicine.
