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Author : Jacob Ellegood
Publisher :
ISBN 13 :
Total Pages : 364 pages
Book Rating : 4.:/5 (474 download)
Download or read book Diffusion Weighted Magnetic Resonance Spectroscopy of Human Brain written by Jacob Ellegood and published by . This book was released on 2008 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Herman Bachelard
Publisher : Springer Science & Business Media
ISBN 13 : 1461558638
Total Pages : 427 pages
Book Rating : 4.4/5 (615 download)
Download or read book Magnetic Resonance Spectroscopy and Imaging in Neurochemistry written by Herman Bachelard and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Advances in Neurochemistry series was initiated for a readership of neuroscientists with a background in biochemistry. True to this concept, the present volume brings together various applications of magnetic resonance technology to advance our knowledge of how the nervous system functions. Whether at the cellular, tissue slice, or intact organism level. magnetic resonance techniques are by their nature noninvasive, and thus provide a window through which biochemical reactions can be viewed without grinding, binding, or other wise perturbing ongoing physiological processes. As technological improve ments in methodology, such as higher and more uniform magnetic fields, novel paradigms for data analysis, etc. , are made, we find increased sensitivity and improved temporal and spatial resolution for functional imaging techniques on the one hand, and better separation of signals that identify chemical properties in spectral shift studies, on the other. It is upon knowledge such as is described in the twelve chapters that follow, that further advances in scientific discovery and the biomedical applications of tomorrow will be based. We are grateful to Dr. Bachelard, the Volume Editor, and to the authors of the individual chapters for their efforts. We also note that with this volume Dr. Morris Aprison, a co-founder of the Advances in Neurochemistry series has stepped down and acknowledge with thanks his major role in its inception. In addition, we thank our past and present Advisory Editors. Bernard W. Agranoff Kunihiko Suzuki Series Editors ix CONTENTS LIST OF SYMBOLS AND GLOSSARY . . . . . . . . . . . . . . . . . . . . . . . . . . . XXI INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Author : Guglielmo Genovese
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (123 download)
Download or read book Evaluation of Microstructural Alterations in the Human Brain and in Experimental Models with Diffusion-weighted Magnetic Resonance Spectroscopy written by Guglielmo Genovese and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffusion-weighted magnetic resonance spectroscopy (DW-MRS) is a unique tool to investigate brain microstructure in a cell-specific manner, while neglecting phenomena related to the extracellular environment. In this thesis, we studied DW-MRS in several complementary ways in order to be able to apply this technique in later clinical studies: optimization of the acquisition pipeline and data analysis, reproducibility of the diffusion measures, and histological validation of the DW-MRS metrics as potential useful markers of brain diseases-related microstructural alterations. The thesis is composed of three parts. In the first part, we propose an optimization of the acquisition and of the post-processing procedures for single-voxel DW-MRS experiments in humans, and an evaluation of the feasibility of a DW-semi-LASER sequence for clinical studies at 3 T. Power calculations for the metabolite diffusion measures were reported in order to provide useful information for designing case-control studies in patients with brain diseases. In the second part, we focused on validating DW-MRS metrics using histological measures in two different mouse models of myelinopathy. A strong correlation was found between mIns diffusivity and the astrocyte area fraction confirming the hypothesis that mIns diffusivity can be used as a marker of astrocyte hypertrophy during the inflammatory process. In the last part, we studied the longitudinal evolution of axonal and glial alterations after ischemic stroke in the human brain. We observed the presence of inflammation due to glial reactivity about one month after ischemic stroke and astrocytic reactivity up to about three months after the ischemic stroke.
Author : Moo K. Chung
Publisher : Cambridge University Press
ISBN 13 : 110718486X
Total Pages : 343 pages
Book Rating : 4.1/5 (71 download)
Download or read book Brain Network Analysis written by Moo K. Chung and published by Cambridge University Press. This book was released on 2019-06-27 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: This coherent mathematical and statistical approach aimed at graduate students incorporates regression and topology as well as graph theory.
Author : Derek K Jones
Publisher : Oxford University Press
ISBN 13 : 0199708703
Total Pages : 784 pages
Book Rating : 4.1/5 (997 download)
Download or read book Diffusion MRI written by Derek K Jones and published by Oxford University Press. This book was released on 2010-11-11 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Professor Derek Jones, a world authority on diffusion MRI, has assembled most of the world's leading scientists and clinicians developing and applying diffusion MRI to produce an authorship list that reads like a "Who's Who" of the field and an essential resource for those working with diffusion MRI. Destined to be a modern classic, this definitive and richly illustrated work covers all aspects of diffusion MRI from basic theory to clinical application. Oxford Clinical Neuroscience is a comprehensive, cross-searchable collection of resources offering quick and easy access to eleven of Oxford University Press's prestigious neuroscience texts. Joining Oxford Medicine Online these resources offer students, specialists and clinical researchers the best quality content in an easy-to-access format.
Author : Società italiana di fisica
Publisher : IOS Press
ISBN 13 : 161499224X
Total Pages : 602 pages
Book Rating : 4.6/5 (149 download)
Download or read book Magnetic Resonance and Brain Function: Approaches from Physics written by Società italiana di fisica and published by IOS Press. This book was released on 1999 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decade, NMR has set the basis for the understanding of the function and disfunction of the human brain. Particularly, Magnetic Resonance Imaging (MRI) has a leading position among the methodologies used for investigation and diagnostic of the Central Nervous System. In the 1990's the objective of finding new investigating means drove scientists towards different approaches, including: 1) Blood Oxygen Level Dependent (BOLD) MRI; 2) Double Magnetic Resonance (DMR); 3) Hyperpolarized Gases. These 3 methods are aimed at detecting brain metabolites with increasing sensitivity and resolution. This Enrico Fermi Course is of interest to researchers who work at the development of these interdisciplinary areas, i.e. physicists, chemists, engineers, but also the biomedical aspects of brain function in connection to the NMR potentialities.
Author : Julien Valette
Publisher : Frontiers Media SA
ISBN 13 : 2889458415
Total Pages : 193 pages
Book Rating : 4.8/5 (894 download)
Download or read book Assessing Cellular Microstructure in Biological Tissues using In Vivo Diffusion-Weighted Magnetic Resonance written by Julien Valette and published by Frontiers Media SA. This book was released on 2019-05-16 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance imaging (MRI) and spectroscopy (MRS) techniques have opened new doors for examining biological tissues in vivo. By combining sensitization to diffusion using magnetic field gradients with a variety of imaging and localization schemes, diffusion-weighted MRI and diffusion-weighted MRS allow investigating translational diffusion of endogenous molecules, such as water or metabolites, in biological tissues, most commonly the brain but also other organs such as the prostate. The typical voxel resolution of MRI or MRS is in the millimeter to centimeter range, much lower than the cellular scale. However, as molecules are typically diffusing over just a few µm during the duration of the measurement (the “diffusion time”) and encounter numerous biological membranes at these scales, the average cellular microstructure has a critical influence on the measured diffusion signal. Hence, diffusion-weighted MRI and diffusion-weighted MRS are sensitive to tissue microstructure at a scale well below the nominal imaging resolution. However, the connection between diffusion properties and tissue microstructure remains indirect, so any attempt to quantify microstructure will rely on modeling. The goal of this Research Topic was to gather experts in various acquisition and modeling strategies and show how these approaches, despite their own strengths and weaknesses, can yield unique information about cellular microstructure, and sometimes complement each other.
Author : Xuan Gu
Publisher : Linköping University Electronic Press
ISBN 13 : 9175190036
Total Pages : 93 pages
Book Rating : 4.1/5 (751 download)
Download or read book Advanced analysis of diffusion MRI data written by Xuan Gu and published by Linköping University Electronic Press. This book was released on 2019-11-19 with total page 93 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffusion magnetic resonance imaging (diffusion MRI) is a non-invasive imaging modality which can measure diffusion of water molecules, by making the MRI acquisition sensitive to diffusion. Diffusion MRI provides unique possibilities to study structural connectivity of the human brain, e.g. how the white matter connects different parts of the brain. Diffusion MRI enables a range of tools that permit qualitative and quantitative assessments of many neurological disorders, such as stroke and Parkinson. This thesis introduces novel methods for diffusion MRI data analysis. Prior to estimating a diffusion model in each location (voxel) of the brain, the diffusion data needs to be preprocessed to correct for geometric distortions and head motion. A deep learning approach to synthesize diffusion scalar maps from a T1-weighted MR image is proposed, and it is shown that the distortion-free synthesized images can be used for distortion correction. An evaluation, involving both simulated data and real data, of six methods for susceptibility distortion correction is also presented in this thesis. A common problem in diffusion MRI is to estimate the uncertainty of a diffusion model. An empirical evaluation of tractography, a technique that permits reconstruction of white matter pathways in the human brain, is presented in this thesis. The evaluation is based on analyzing 32 diffusion datasets from a single healthy subject, to study how reliable tractography is. In most cases only a single dataset is available for each subject. This thesis presents methods based on frequentistic (bootstrap) as well as Bayesian inference, which can provide uncertainty estimates when only a single dataset is available. These uncertainty measures can then, for example, be used in a group analysis to downweight subjects with a higher uncertainty.
Author : Madan M Kaila
Publisher : Elsevier
ISBN 13 : 0123847125
Total Pages : 517 pages
Book Rating : 4.1/5 (238 download)
Download or read book Quantum Magnetic Resonance Imaging Diagnostics of Human Brain Disorders written by Madan M Kaila and published by Elsevier. This book was released on 2010-06-21 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic resonance imaging (MRI) is a medical imaging technique used to visualize detailed internal structure of the body. This book discusses the recent developments in the field of MRI and its application to the diagnosis of human brain disorders. In addition, it reviews the newly emerging concepts and technology, based on the multi-coherence imaging (MQCI). It explains how computer packages can be used to generate images in diseased states and compare them to in vivo results. This will help improve the diagnosis of brain disorders based on the real-time events happening on atomic and molecular quantum levels. This is important since quantum-based MRI would enable clinicians to detect brain tumors at the very early stages. Uses practical examples to explain the techniques - making it easier to understand the concepts Uses diagrams to explain the physics behind the technique - avoiding the use of complicated mathematical formulae
Author : Tommaso Scarabino
Publisher : Springer
ISBN 13 : 3319441744
Total Pages : 385 pages
Book Rating : 4.3/5 (194 download)
Download or read book High Field Brain MRI written by Tommaso Scarabino and published by Springer. This book was released on 2017-02-27 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the development of systems of magnetic resonance imaging using the higher magnetic field strength of 3 tesla, in comparison to the current gold standard of 1.5 tesla. These new systems of MRI make it possible to perform with high spatial, temporal and contrast resolution not only morphological examinations but also functional studies on spectroscopy, diffusion, perfusion, and cortical activation, thus helping research and providing an important tool for routine diagnostic activity. At the same time the new systems offer unparalleled sensitivity and specificity in the numerous conditions of neuroradiological interest.
Author : Jörg Polzehl
Publisher : Springer Nature
ISBN 13 : 3031389492
Total Pages : 268 pages
Book Rating : 4.0/5 (313 download)
Download or read book Magnetic Resonance Brain Imaging written by Jörg Polzehl and published by Springer Nature. This book was released on 2023-11-12 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses modelling and analysis of Magnetic Resonance Imaging (MRI) data of the human brain. For the data processing pipelines we rely on R, the software environment for statistical computing and graphics. The book is intended for readers from two communities: Statisticians, who are interested in neuroimaging and look for an introduction to the acquired data and typical scientific problems in the field and neuroimaging students, who want to learn about the statistical modeling and analysis of MRI data. Being a practical introduction, the book focuses on those problems in data analysis for which implementations within R are available. By providing full worked-out examples the book thus serves as a tutorial for MRI analysis with R, from which the reader can derive its own data processing scripts. The book starts with a short introduction into MRI. The next chapter considers the process of reading and writing common neuroimaging data formats to and from the R session. The main chapters then cover four common MR imaging modalities and their data modeling and analysis problems: functional MRI, diffusion MRI, Multi-Parameter Mapping and Inversion Recovery MRI. The book concludes with extended Appendices on details of the utilize non-parametric statistics and on resources for R and MRI data. The book also addresses the issues of reproducibility and topics like data organization and description, open data and open science. It completely relies on a dynamic report generation with knitr: The books R-code and intermediate results are available for reproducibility of the examples.
Author : Heidi Johansen-Berg
Publisher : Academic Press
ISBN 13 : 0124055095
Total Pages : 627 pages
Book Rating : 4.1/5 (24 download)
Download or read book Diffusion MRI written by Heidi Johansen-Berg and published by Academic Press. This book was released on 2013-11-04 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments. Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo. This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie. Fully revised and updated edition of the first comprehensive reference on a powerful technique in brain imaging Covers all aspects of a diffusion MRI study from acquisition through analysis to interpretation, and from fundamental theory to cutting-edge developments New chapters covering connectomics, advanced diffusion acquisition, artifact removal, and applications to the neonatal brain Provides practical advice on running an experiment Includes discussion of applications in psychiatry, neurology, neurosurgery, and basic neuroscience Full color throughout
Author : Jonathan H. Gillard
Publisher : Cambridge University Press
ISBN 13 : 9781139455701
Total Pages : 906 pages
Book Rating : 4.4/5 (557 download)
Download or read book Clinical MR Neuroimaging written by Jonathan H. Gillard and published by Cambridge University Press. This book was released on 2004-12-02 with total page 906 pages. Available in PDF, EPUB and Kindle. Book excerpt: The physiological magnetic resonance techniques of diffusion imaging, perfusion imaging and spectroscopy offer insights into brain structure, function and metabolism. Until recently, they were mainly applied within the realm of medical research, but with their increasing availability on clinical MRI machines, they are now coming into clinical practice for the evaluation of neuropathology in individual patients. This book provides the reader with a thorough review of the underlying physical principles of each of these methods, as well as comprehensive coverage of their clinical applications. Topics covered include single- and multiple-voxel MRS techniques, MR perfusion based on both arterial spin labelling and dynamic bolus tracking approaches, and diffusion-weighted imaging, including techniques for mapping brain white matter fiber bundles. Clinical applications are reviewed in depth for each technique, with case reports included throughout the book. Attention is also drawn to possible artifacts and pitfalls associated with these techniques.
Author : Yoshiaki Toyama
Publisher : Springer Nature
ISBN 13 : 9811379084
Total Pages : 292 pages
Book Rating : 4.8/5 (113 download)
Download or read book Make Life Visible written by Yoshiaki Toyama and published by Springer Nature. This book was released on 2019-10-02 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completelyimpossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology inthe broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into three parts, the first of which addresses the topic of visualizing and controlling molecules for life. Th e second part is devoted to imaging of disease mechanisms, while the final part comprises studies on the application of imaging technologies to diagnosis and therapy. Th e book contains the proceedings of the 12th Uehara International Symposium 2017, “Make Life Visible” sponsored by the Uehara Memorial Foundation and held from June 12 to 14, 2017. It is written by leading scientists in the field and is an open access publication under a CC BY 4.0 license.
Author : Evren Özarslan
Publisher : Springer Nature
ISBN 13 : 3030562158
Total Pages : 284 pages
Book Rating : 4.0/5 (35 download)
Download or read book Anisotropy Across Fields and Scales written by Evren Özarslan and published by Springer Nature. This book was released on 2021 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on processing, modeling, and visualization of anisotropy information, which are often addressed by employing sophisticated mathematical constructs such as tensors and other higher-order descriptors. It also discusses adaptations of such constructs to problems encountered in seemingly dissimilar areas of medical imaging, physical sciences, and engineering. Featuring original research contributions as well as insightful reviews for scientists interested in handling anisotropy information, it covers topics such as pertinent geometric and algebraic properties of tensors and tensor fields, challenges faced in processing and visualizing different types of data, statistical techniques for data processing, and specific applications like mapping white-matter fiber tracts in the brain. The book helps readers grasp the current challenges in the field and provides information on the techniques devised to address them. Further, it facilitates the transfer of knowledge between different disciplines in order to advance the research frontiers in these areas. This multidisciplinary book presents, in part, the outcomes of the seventh in a series of Dagstuhl seminars devoted to visualization and processing of tensor fields and higher-order descriptors, which was held in Dagstuhl, Germany, on October 28-November 2, 2018.
Author : Nicole Seiberlich
Publisher : Academic Press
ISBN 13 : 0128170581
Total Pages : 1094 pages
Book Rating : 4.1/5 (281 download)
Download or read book Quantitative Magnetic Resonance Imaging written by Nicole Seiberlich and published by Academic Press. This book was released on 2020-11-18 with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches
Author : Denis Le Bihan
Publisher : Raven Press (ID)
ISBN 13 :
Total Pages : 418 pages
Book Rating : 4.3/5 (91 download)
Download or read book Diffusion and Perfusion Magnetic Resonance Imaging written by Denis Le Bihan and published by Raven Press (ID). This book was released on 1995 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt:
