Dictyostelium A Model System For Cell And Developmental Biology

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Dictyostelium Discoideum

Author : William Loomis
Publisher : Elsevier
ISBN 13 : 032315980X
Total Pages : 225 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Dictyostelium Discoideum by : William Loomis

Download or read book Dictyostelium Discoideum written by William Loomis and published by Elsevier. This book was released on 2012-12-02 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dictyostelium Discoideum: A Developmental System presents D. discoideum as a model eukaryotic system to study a variety of developmental problems. The book describes the life cycle of the organism D. discoideum which exists in nature as a soil amoeba in forest detritus. The nuclei of D. discoideum contain DNA, RNA, and proteins which have properties similar to those of histones present in calf thymus nuclei. The unique sequences of the genome of the organism code for the gene products synthesize during its growth and development. One approach in genetic analyses to understanding the developmental processes of the organism is to isolate a large number of morphological mutants. The isolation process will indicate the number of variations that are open to the developing system, and will point to causal connections between stages. The text also explains that the number of cells which differentiate into stalk cells is the result of timing and mechanics of the process of culmination. Ashworth (1971) suggests that cells in pseudoplasmodia of D. discoideum adjust their positions in relation to the chemical structure of the sheath itself. A model shows how cells communicate their response to the sheath in an axial fashion. The book can prove beneficial for biochemists, micro-biologists, cellular researchers, and investigators involved in the study of cellular biology.

Dictyostelium discoideum Protocols

Author : Ludwig Eichinger
Publisher : Springer Science & Business Media
ISBN 13 : 1597451444
Total Pages : 556 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Dictyostelium discoideum Protocols by : Ludwig Eichinger

Download or read book Dictyostelium discoideum Protocols written by Ludwig Eichinger and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dictyostelium discoideum is a simple but fascinating eukaryotic microorg- ism, whose natural habitat is deciduous forest soil and decaying leaves, where the amoebae feed on bacteria and grow as independent single cells. Exhaustion of the bacterial food source triggers a developmental program, in which up to 100,000 cells aggregate by chemotaxis towards cAMP. Morphogenesis and cell different- tion then culminate in the production of spores enabling the organism to survive unfavorable conditions. Dictyostelium offers unique advantages for studying f- damental cellular processes with the aid of powerful molecular genetic, bioche- cal, and cell biological tools. These processes include signal transduction, chemotaxis, cell motility, cytokinesis, phagocytosis, and aspects of development such as cell sorting, pattern formation and cell type differentiation. Recently, D- tyostelium was also described as a suitable host for pathogenic bacteria in which one can conveniently study the process of infection. In addition, Dictyostelium has many of the experimental conveniences of Saccharomyces cerevisiae and is pr- ably the best experimentally manipulatable protozoan, providing insight into this diverse group of organisms, which includes some of the most dangerous human parasites. The recent completion of the Dictyostelium genome sequencing project strengthens the position of D. discoideum as a model organism. The completed genome sequence and other valuable community resources constitute the source for basic biological and biomedical research and for genome-wide analyses.

Dictyostelids

Author : Maria Romeralo
Publisher : Springer Science & Business Media
ISBN 13 : 3642384870
Total Pages : 259 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Dictyostelids by : Maria Romeralo

Download or read book Dictyostelids written by Maria Romeralo and published by Springer Science & Business Media. This book was released on 2013-07-16 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since their discovery in 1869, the dictyostelids have attracted the attention of scientists in a wide variety of fields. This interest has stemmed from their peculiar lifestyle and developmental properties, which were shaped by the evolutionary forces that generated multicellularity during eukaryotic evolution. More recently, the dictyostelids have gained attention due to the striking similarities found at the genomic, cellular and biochemical levels with human cells, which has propelled the species Dictyostelium discoideum to become a model system for biology and medicine in many laboratories. This book covers the latest advances in our knowledge of these extraordinary organisms with topics spanning from their evolutionary history, ecology and diversity to the recent discoveries regarding their cellular and molecular biology.

Dictyostelium, a Model System for Cell and Developmental Biology

Author : Yasuo Maeda
Publisher :
ISBN 13 : 9784946443459
Total Pages : 488 pages
Book Rating : 4.4/5 (434 download)

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Book Synopsis Dictyostelium, a Model System for Cell and Developmental Biology by : Yasuo Maeda

Download or read book Dictyostelium, a Model System for Cell and Developmental Biology written by Yasuo Maeda and published by . This book was released on 1997 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Dictyostelium

Author : Richard H. Kessin
Publisher : Cambridge University Press
ISBN 13 : 0521583640
Total Pages : 318 pages
Book Rating : 4.5/5 (215 download)

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Book Synopsis Dictyostelium by : Richard H. Kessin

Download or read book Dictyostelium written by Richard H. Kessin and published by Cambridge University Press. This book was released on 2001-01-11 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dictyostelia are soil amoebae capable of extraordinary feats of survival, motility, chemotaxis, and development. Characterised by their ability to transform from a single-celled organism into an elaborate assemblage of thousands of synchronously-moving cells, Dictyostelids are often referred to as 'social amoebae', and have been the subjects of serious study since the 1930s. Research in this area has been instrumental in understanding many problems in cellular biology. Beginning with the history of Dictyostelids and discussing each stage of their development, this book considers the evolution of this unique organism, analyses the special properties of the Dictyostelid genome, and presents in detail the methods available, at the time of the book's original publication in 2001, to manipulate their genes. Representing the synthesis of such material and with an emphasis on combining classical experiments with modern molecular findings, this book will be essential for researchers and graduates in developmental and cellular biology.

Dictyostelium discoideum Protocols

Author : Ludwig Eichinger
Publisher : Humana Press
ISBN 13 : 9781493959976
Total Pages : 479 pages
Book Rating : 4.9/5 (599 download)

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Book Synopsis Dictyostelium discoideum Protocols by : Ludwig Eichinger

Download or read book Dictyostelium discoideum Protocols written by Ludwig Eichinger and published by Humana Press. This book was released on 2016-08-23 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dictyostelium discoideum is a well-establish eukaryotic model organism that offers unique advantages for studying fundamental cellular processes, including signal transduction, random and directed cell motility, cytokinesis, endocytosis and vesicle transport and development. Dictyostelium is also increasingly used for the investigation of human disease genes and the crosstalk between host and pathogen. The availability of the genome sequence at a mouse click together with a whole range of supporting information and resources along with a powerful armoury of molecular genetics techniques have considerably enhanced the experimental attractiveness of D. discoideum in recent years. The second edition of Dictyostelium discoideum Protocols incorporates the most recent developments in a number of fields. The book is divided into four parts. The first part provides an introduction to the amoebozoa and community resources. The second part presents large-scale analysis methods made possible by the completion of the Dictyostelium genome sequence. The third part is dedicated to molecular genetics techniques, cell biological, biochemical and biophysical methods. The chapters in the fourth part describe the use of Dictyostelium as a model system to study vesicle formation, trafficking and infection by bacterial pathogens. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Dictyostelium discoideum Protocols, Second Edition seeks to aid scientists in the application of innovating techniques to study a range of fundamental biological processes in this attractive model organism.

The Development Of Dictyostelium Discoideum

Author : William Loomis
Publisher : Elsevier
ISBN 13 : 0323145663
Total Pages : 570 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis The Development Of Dictyostelium Discoideum by : William Loomis

Download or read book The Development Of Dictyostelium Discoideum written by William Loomis and published by Elsevier. This book was released on 2012-12-02 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Development of Dictyostelium discoideum consists of 11 chapters representing the 11 major aspects at which continuous progress are made in the study of Dictyostelium discoideum. This book begins with the discovery, classification, ecology, and development of Dictyostelium discoideum. It then outlines the advances in genetic manipulation and mutant isolation of the organism. Much of the advances in cell biology have been related to a better understanding of the composition and function of the cell membrane. Hence, analyses of Dictyostelium plasma membranes are collated. This reference material also describes the role of chemoattractants in organizing cell movements and the intracellular events triggered by occupancy of chemoreceptors. It also explains the understanding of the macromolecular components of the chemosensory system of Dictyostelium discoideum. It further discusses the cell motility, cell adhesion, morphogenetic signaling, cytodifferentiation, and gene expression in the species. Finally, the phenomenon of cell-type specification and regulation in this organism is addressed. This book will be valuable for those already familiar with the general outlines of Dictyostelium biology.

Dictyostelium Discoideum

Author : William F. Loomis
Publisher :
ISBN 13 : 9780124561502
Total Pages : 0 pages
Book Rating : 4.5/5 (615 download)

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Book Synopsis Dictyostelium Discoideum by : William F. Loomis

Download or read book Dictyostelium Discoideum written by William F. Loomis and published by . This book was released on 1975 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research

Author : Robert T. Gerlai
Publisher : Academic Press
ISBN 13 : 0128041161
Total Pages : 710 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research by : Robert T. Gerlai

Download or read book Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research written by Robert T. Gerlai and published by Academic Press. This book was released on 2018-04-24 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. - Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials - Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior - Written and edited by leading international experts

Dictyostelium Genomics

Author : William F. Loomis
Publisher : Taylor & Francis
ISBN 13 : 9781904933137
Total Pages : 302 pages
Book Rating : 4.9/5 (331 download)

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Book Synopsis Dictyostelium Genomics by : William F. Loomis

Download or read book Dictyostelium Genomics written by William F. Loomis and published by Taylor & Francis. This book was released on 2005 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dictyostelium discoideum is a model eukaryotic organism for basic biomedical research in cell and developmental biology and for the functional analysis of sequenced genes. The organism has unique advantages for studying fundamental cellular processes such as cytokinesis, motility, phagocytosis, chemotaxis, signal transduction, cell sorting, pattern formation, and cell-type determination. This book, written to coincide with the publication of the genome sequence of Dictyostelium, introduces the post-genomic era and focuses on the important aspects of Dictyostelium genomics. Leading experts in the field have contributed chapters on genomic mapping and sequencing, databases, multigene families, regulation of gene expression, signal transduction, the microfilament system, the GTPase superfamily, the kinome, glycosyltransferase genomics, and whole-genome functional analysis.

Current Protocols Essential Laboratory Techniques

Author : Sean R. Gallagher
Publisher : John Wiley & Sons
ISBN 13 : 047094241X
Total Pages : 679 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Current Protocols Essential Laboratory Techniques by : Sean R. Gallagher

Download or read book Current Protocols Essential Laboratory Techniques written by Sean R. Gallagher and published by John Wiley & Sons. This book was released on 2012-03-19 with total page 679 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest title from the acclaimed Current Protocols series, Current Protocols Essential Laboratory Techniques, 2e provides the new researcher with the skills and understanding of the fundamental laboratory procedures necessary to run successful experiments, solve problems, and become a productive member of the modern life science laboratory. From covering the basic skills such as measurement, preparation of reagents and use of basic instrumentation to the more advanced techniques such as blotting, chromatography and real-time PCR, this book will serve as a practical reference manual for any life science researcher. Written by a combination of distinguished investigators and outstanding faculty, Current Protocols Essential Laboratory Techniques, 2e is the cornerstone on which the beginning scientist can develop the skills for a successful research career.

The Social Amoebae

Author : John Tyler Bonner
Publisher : Princeton University Press
ISBN 13 : 9780691139395
Total Pages : 164 pages
Book Rating : 4.1/5 (393 download)

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Book Synopsis The Social Amoebae by : John Tyler Bonner

Download or read book The Social Amoebae written by John Tyler Bonner and published by Princeton University Press. This book was released on 2009-01-18 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Noted biologist and author John Tyler Bonner has experimented with cellular slime molds for more than sixty years, and he has done more than anyone else to raise these peculiar collections of amoebae from a minor biological curiosity to a major model organism--one that is widely studied for clues to the development and evolution of all living things. Now, five decades after he published his first pioneering book on cellular slime molds, Bonner steps back from the proliferating and increasingly specialized knowledge about the organism to provide a broad, nontechnical picture of its whole biology, including its evolution, sociobiology, ecology, behavior, and development. The Social Amoebae draws the big lessons from decades of research, and shows how slime molds fit into and illuminate biology as a whole. Slime molds are very different from other organisms; they feed as individual amoebae before coming together to form a multicellular organism that has a remarkable ability to move and orient itself in its environment. Furthermore, these social amoebae display a sophisticated division of labor; within each organism, some cells form the stalk and others become the spores that will seed the next generation. In The Social Amoebae, Bonner examines all these parts together, giving a balanced, concise, and clear overview of slime mold biology, from molecules to cells to multicells, as he advances some unconventional and unexpected insights.

Molecular Biology of Dictyostelium Development

Author : Alan R. Kimmel
Publisher : Alan R. Liss
ISBN 13 :
Total Pages : 508 pages
Book Rating : 4.:/5 (5 download)

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Book Synopsis Molecular Biology of Dictyostelium Development by : Alan R. Kimmel

Download or read book Molecular Biology of Dictyostelium Development written by Alan R. Kimmel and published by Alan R. Liss. This book was released on 1988 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cdc2 Links the Cell Division Cycle to Differentiation in Dictyostelium Discoideum

Author : Kimchi Doquang
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (11 download)

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Book Synopsis Cdc2 Links the Cell Division Cycle to Differentiation in Dictyostelium Discoideum by : Kimchi Doquang

Download or read book Cdc2 Links the Cell Division Cycle to Differentiation in Dictyostelium Discoideum written by Kimchi Doquang and published by . This book was released on 2003 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Dictyostelium discoideum, a multicellular organism stems from individual amoebae in response to nutrient depletion. Despite the vastly different strategy used to generate multicellular structures, processes associated with animal development including cell sorting, pattern formation and cell-type choice are mirrored to a remarkable degree in the development of Dictyostelium . Morphogenesis ultimately leads to the formation of a fruiting body composed of dormant spores mounted on a rigid stalk of dead cells. The simplicity of this dichotomous choice makes Dictyostelium a model system for the study of pattern formation in developing organisms. Several lines of evidence suggest that cell-type biases are directly linked to the cell cycle. Cells starved early in the cell cycle preferentially become the stalk cells while those starved in later phases of the cell cycle favour the spore pathway [Weijer, C., Duschl, G., David, C.N. (1984) J. Cell Sci ., 70, 133-145; MacDonald, S.A., Durston, A.J. (1984) J. Cell Sci ., 66, 195-204; Gomer, R.H., Firtel, R.A. (1987) Science, 237, 758-762; Ohmori, T., Maeda, Y. (1987) Cell Differentiation, 25, 11-18; Zimmerman, W., Weijer, C. (1993) Developmental Biology, 160, 178-185; Araki, T., Hajime, N., Takeuchi, I., Maeda, Y. (1994) Developmental Biology, 162, 221-228]. The underlying mechanism linking the cell cycle to cellular differentiation is unclear. To gain a better understanding of the relationship we have undertaken the analysis of proteins controlling the cell division cycle. In this work we describe a mutation in Cdc2 kinase, a pivotal cell cycle control element, and demonstrate that the cell-cycle control mechanism contributes directly to cell-type biases.

Molecular Biology of Dictyostelium Development

Author : Alan R. Kimmel
Publisher : Wiley-Liss
ISBN 13 : 9780471505068
Total Pages : 500 pages
Book Rating : 4.5/5 (5 download)

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Book Synopsis Molecular Biology of Dictyostelium Development by : Alan R. Kimmel

Download or read book Molecular Biology of Dictyostelium Development written by Alan R. Kimmel and published by Wiley-Liss. This book was released on 1989-02-07 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: This compilation of the work of international researchers provides a comprehensive overview of Dictyostelium discoideum and related dictyostelid cellular slime mold species. Using a multidisciplinary approach, it applies biochemical, genetic and molecular techniques to the dissection of developmental mutants in existence for over a decade. Divided into four sections covering the molecular biology of signalling, regulated gene expression, cytoskeletal and cell-surface events, and patterning.

Dictyostelium discoideum

Author : Alan R. Kimmel
Publisher : Springer Nature
ISBN 13 : 1071638947
Total Pages : 261 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Dictyostelium discoideum by : Alan R. Kimmel

Download or read book Dictyostelium discoideum written by Alan R. Kimmel and published by Springer Nature. This book was released on with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Dictyostelids

Author : Kenneth Bryan Raper
Publisher : Princeton University Press
ISBN 13 : 1400856566
Total Pages : 467 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis The Dictyostelids by : Kenneth Bryan Raper

Download or read book The Dictyostelids written by Kenneth Bryan Raper and published by Princeton University Press. This book was released on 2014-07-14 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kenneth Raper tells how dictyostelids are isolated, cultivated, and conserved in the laboratory; how myxamoebae aggregate to form multicellular pseudoplasmodia; how fructifications arise by transformation of amoeboid cells into stalk cells and spores; and how similar cells can, under certain conditions, enter a sexual phase. For each known dictyostelid Professor Raper includes a complete description and photographic illustrations; one new species is described. Originally published in 1984. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.