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Development And Characterization Of Biodegradable Polymeric Nanoparticles For Gene Delivery
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Book Synopsis Nanotechnology Applied To Pharmaceutical Technology by : Mahendra Rai
Download or read book Nanotechnology Applied To Pharmaceutical Technology written by Mahendra Rai and published by Springer. This book was released on 2017-11-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on the application of nanotechnology in pharmaceutical technology the editors seek to integrate the two in order to obtain innovative products and solutions in pharmacology. Interdisciplinary in content it is of interest to those who are involved in the development of nanoproducts including nanotechnologists, microbiologists, biotechnologists pharmacologists and clinicians. Recent studies are presented that include the biosynthesis of nanoparticles focusing on antimicrobials; nanomaterial-based formulations that treat cancer, infections, skin disorders and wounds;nanomaterials in eye diseases and toxicity and safety issues. It demonstrates the crucial role this plays in tackling multi-drug resistant threats.
Book Synopsis Drug Delivery Nanoparticles Formulation and Characterization by : Yashwant Pathak
Download or read book Drug Delivery Nanoparticles Formulation and Characterization written by Yashwant Pathak and published by CRC Press. This book was released on 2016-04-19 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exploring fundamental concepts, Drug Delivery Nanoparticles Formulation and Characterization presents key aspects of nanoparticulate system development for various therapeutic applications and provides advanced methods used to file for regulatory approval.This comprehensive guide features:Process Analytical Techniques (PAT) used in manufacturing Na
Book Synopsis Targeted Delivery of Pesticides Using Biodegradable Polymeric Nanoparticles by : Arnab De
Download or read book Targeted Delivery of Pesticides Using Biodegradable Polymeric Nanoparticles written by Arnab De and published by Springer Science & Business Media. This book was released on 2013-11-18 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brief is the first to focus exclusively on environmentally friendly delivery of pesticides (controlled-release nanoparticulate formulation of pesticides using biodegradable polymers as carriers). The brief also introduces pesticides like Chlorpyrifos and biodegradable polymers like guar-gum. The brief will be extremely useful to the researchers in the field of agrochemicals and will be equally useful for advanced professionals in the field of biology, chemistry, environmental biology, entomology and horticulture.
Book Synopsis Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment by : Jorge Coelho
Download or read book Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment written by Jorge Coelho and published by Springer Science & Business Media. This book was released on 2013-03-15 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is part of a series dedicated to recent advances on preventive, predictive and personalised medicine (PPPM). It focuses on the theme of “Drug delivery systems: advanced technologies potentially applicable in personalised treatments”. The critical topics involving the development and preparation of effective drug delivery systems, such as: polymers available, self-assembly, nanotechnology, pharmaceutical formulations, three dimensional structures, molecular modeling, tailor-made solutions and technological tendencies, are carefully discussed. The understanding of these areas constitutes a paramount route to establish personalised and effective solutions for specific diseases and individuals.
Book Synopsis Polymers and Nanomaterials for Gene Therapy by : Ravin Narain
Download or read book Polymers and Nanomaterials for Gene Therapy written by Ravin Narain and published by Woodhead Publishing. This book was released on 2016-01-09 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy. This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy. - Explores current challenges in the research of genetic diseases - Discusses polymers for gene therapy and their function in designing advanced materials - Provides examples of organic and inorganic nanomaterials for gene therapy - Includes labeling, targeting, and assays - Looks at characterization, physico-(bio)chemical properties, and applications
Book Synopsis Electrospun Materials and Their Allied Applications by : Inamuddin
Download or read book Electrospun Materials and Their Allied Applications written by Inamuddin and published by John Wiley & Sons. This book was released on 2020-05-27 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to explore the history, fundamentals, manufacturing processes, optimization parameters, and applications of electrospun materials. The book includes various types of electrospun materials such as antimicrobial, smart, bioinspired systems. It focuses on the many application areas for electrospun materials such as energy storage and harvesting, catalysis, biomedical including gene delivery and tissue engineering, separation, adsorption and water treatment technologies, packaging. The book emphasizes the enhanced sustainable properties of electrospun materials, with the challenges and future developments being discussed in detail. The chapters are written by top-class researchers and experts from throughout the world.
Book Synopsis Nanotechnology and Drug Delivery, Volume Two by : Jose L. Arias
Download or read book Nanotechnology and Drug Delivery, Volume Two written by Jose L. Arias and published by CRC Press. This book was released on 2016-04-21 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent introduction of nanomedicines in the drug therapy arena is revolutionizing the management of severe diseases. The key advance in the field is the optimization of the biological fate of drug molecules, thus improving the therapeutic effect while keeping to a very minimum the associated toxicity. Volume one of this book series, Nanoplatfor
Book Synopsis Translocator Protein (TSPO) by : Giovanni Natile
Download or read book Translocator Protein (TSPO) written by Giovanni Natile and published by MDPI. This book was released on 2018-03-05 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Translocator Protein (TSPO)" that was published in IJMS
Book Synopsis Nanoengineering of Biomaterials by : Sougata Jana
Download or read book Nanoengineering of Biomaterials written by Sougata Jana and published by John Wiley & Sons. This book was released on 2022-04-18 with total page 1063 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive discussion of various types of nanoengineered biomaterials and their applications In Nanoengineering of Biomaterials: Drug Delivery & Biomedical Applications, an expert team of chemists delivers a succinct exploration of the synthesis, characterization, in-vitro and in-vivo drug molecule release, pharmacokinetic activity, pharmacodynamic activity, and the biomedical applications of several types of nanoengineered biomaterials. The editors have also included resources to highlight the most current developments in the field. The book is a collection of valuable and accessible reference sources for researchers in materials chemistry and related disciplines. It uses a functions-directed approach to using organic and inorganic source compounds that translate into biological systems as scaffolds, micelles, dendrimers, and other delivery systems. Nanoengineering of Biomaterials offers readers up-to-date chemistry and material science insights that are readily transferrable to biomedical systems. The book also includes: Thorough introductions to alginate nanoparticle delivery of therapeutics and chitosan-based nanomaterials in biological applications Comprehensive explorations of nanostructured carrageenan as a drug carrier, gellan gum nanoparticles in drug delivery, and guar-gum nanoparticles in the delivery of bioactive molecules Practical discussions of protein-based nanoparticles for drug delivery, solid lipid nanoparticles as drug carriers, and pH-responsive nanoparticles in therapy In-depth examinations of stimuli-responsive nano carriers in drug targeting Perfect for pharmaceutical chemists, materials scientists, polymer chemists, life scientists, and medicinal chemists, Nanoengineering of Biomaterials: Drug Delivery and Biomedical Applications is also an indispensable resource for biologists and bioengineers seeking a one-stop reference on the transferability of materials chemistry and nanotechnology to biomedicine.
Book Synopsis Seaweed Polysaccharides by : Jayachandran Venkatesan
Download or read book Seaweed Polysaccharides written by Jayachandran Venkatesan and published by Elsevier. This book was released on 2017-05-30 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Seaweed Polysaccharides: Isolation, Biological, and Biomedical Applications examines the isolation and characterization of algal biopolymers, including a range of new biological and biomedical applications. In recent years, significant developments have been made in algae-based polymers (commonly called polysaccharides), and in biomedical applications such as drug delivery, wound dressings, and tissue engineering. Demand for algae-based polymers is increasing and represent a potential—very inexpensive—resource for these applications. The structure and chemical modification of algal polymers are covered, as well as the biological properties of these materials – including antithrombic, anti-inflammatory, anticoagulant, and antiviral aspects. Toxicity of algal biopolymers is also covered. Finally, the book introduces and explains real world applications of algal-based biopolymers in biomedical applications, including tissue engineering, drug delivery, and biosensors. This is the first book to cover the extraction techniques, biomedical applications, and the economic perspective of seaweed polysaccharides. It is an essential text for researchers and industry professionals looking to work with this renewable resource. - Provides comprehensive coverage of the research currently taking place in biomedical applications of algae biopolymers - Includes practical guidance on the isolation, extraction, and characterization of polysaccharides from sustainable marine sources - Covers the extraction techniques, biomedical applications, and economic outlook of seaweed polysaccharides
Book Synopsis Systemic Delivery Technologies in Anti-Aging Medicine: Methods and Applications by : Wing-Fu Lai
Download or read book Systemic Delivery Technologies in Anti-Aging Medicine: Methods and Applications written by Wing-Fu Lai and published by Springer Nature. This book was released on 2020-10-19 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a multidisciplinary assessment of the state of science in the use of systemic delivery technologies to deliver anti-aging therapeutics now under development. There is a gap between basic aging research and the development of intervention technologies. This major obstacle must be overcome before biogerontological interventions can be put into clinical practice. As biogerontology comes to understand aging as a systemic degenerative process, it is clear that there is a pressing need for technologies that enable cells and tissues in a fully developed adult body to be manipulated systemically to combat aging. The authors review advances in the chemistry and engineering of systemic delivery methods and analyze the strengths and limitations of each. The book is organized into six sections. The first offers an overview of the need for systemic delivery technologies alongside the development of anti-aging therapies and describes approaches that will be required for studying the properties and efficiency of carriers for systemic delivery. Sections II, III and IV describe recent advances in a range of strategies that may enable systemic delivery to help combat aging conditions ranging from cell senescence to decline in immune function and hormonal secretion. Section V discusses practical strategies to engineer and optimize the performance of delivery technologies for applications in systemic delivery, along with their working principles. The final section discusses technical and biological barriers that must be overcome as systemic delivery technologies move from research laboratory to clinical applications aimed at tackling aging and age-associated diseases. Benefiting scholars, students and a broader audience of interested readers, the book includes helpful glossary sections in each chapter, as well as sidebars that highlight important notes, and questions for future research.
Book Synopsis Nanobiomaterials by : Thandapani Gomathi
Download or read book Nanobiomaterials written by Thandapani Gomathi and published by CRC Press. This book was released on 2023-10-13 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanobiomaterials: Research Trends and Applications – Biomaterials are derived from natural resources such as plants, animals and marine sources. These biomaterials have advanced applications, across a range of key industries due to their low cost, being easy to process, being biocompatible and so on. The modification of biomaterials in the nanoform enhances their applications. The book begins with an overview of nanobiomaterials, processing, classifications, fabrication and sustainability. In-depth chapters in Part I address the most recent methods and techniques for physicochemical characterisation, processing of blends and composites based on nanomaterials, and separation. Chapters in Part II focus on the biological and biomedical applications specifically in antimicrobial chemotherapy, drug delivery, tissue engineering, cancer therapeutics, robust biosolar cells, and 3D printing. The chapters in Part III mostly focus on environmental applications, including wastewater treatment, water desalination, bioremediation, and agricultural uses. The book is extremely useful for scientists, R&D specialists, designers, and engineers across sectors and disciplines who are interested in using biopolymers for parts and products.
Book Synopsis Engineering Polymer Systems for Improved Drug Delivery by : Rebecca A. Bader
Download or read book Engineering Polymer Systems for Improved Drug Delivery written by Rebecca A. Bader and published by John Wiley & Sons. This book was released on 2014-01-17 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-specialists as well as a graduate level text for drug delivery courses.
Book Synopsis Natural Polymer Drug Delivery Systems by : Saurabh Bhatia
Download or read book Natural Polymer Drug Delivery Systems written by Saurabh Bhatia and published by Springer. This book was released on 2016-09-23 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes 200 bio-polymers, including the most recent and advanced nanotechnology applications. The applications of various bio-medical and other future potential uses are covered and examined in depth. Systematic discussion of current leading natural polymers is also included.
Book Synopsis Polymer Nanoparticles for Nanomedicines by : Christine Vauthier
Download or read book Polymer Nanoparticles for Nanomedicines written by Christine Vauthier and published by Springer. This book was released on 2017-01-07 with total page 649 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume serves as a valuable handbook for the development of nanomedicines made of polymer nanoparticles because it provides researchers, students, and entrepreneurs with all the material necessary to begin their own projects in this field. Readers will find protocols to prepare polymer nanoparticles using different methods, since these are based on the variety of experiences that experts encounter in the field. In addition, complex topics such as, the optimal characterization of polymer nanoparticles is discussed, as well as practical guidelines on how to formulate polymer nanoparticles into nanomedicines, and how to modify the properties of nanoparticles to give them the different functionalities required to become an efficient nanomedicine for different clinical applications. The book also discusses the translation of technology from research to practice, considering aspects related to industrialization of preparation and aspects of regulatory and clinical development.
Book Synopsis Nanoparticulates As Drug Carriers by : Vladimir P Torchilin
Download or read book Nanoparticulates As Drug Carriers written by Vladimir P Torchilin and published by World Scientific. This book was released on 2006-09-29 with total page 755 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by key experts in the field of nanomedicine, this book provides a broad introduction to the important field of nanomedicine and application of nanotechnology for drug delivery. It covers up-to-date information regarding various nanoparticulate drug delivery systems, describes the various opportunities for the application of nanoparticular drug carriers in different areas of clinical medicine, and analyzes already available information on their clinical applications.This book can be used as an advanced textbook by graduate students and young scientists and clinicians at the early stages of their career. It is also suitable for non-experts from related areas of chemistry, biochemistry, molecular biology, biomedical engineering, physiology, experimental and clinical medicine, and pharmaceutical sciences, who are interested in general problems of drug delivery and drug targeting, as well as in more specialized topics of using nanoparticulate-mediated drug delivery approaches in the individual areas of clinical medicine.Prof Torchilin is an expert in Nanomedicine and a recipient of numerous awards including the Lenin Prize in Science & Technology of the former USSR, membership in the European Academy of Sciences, and AAPS Research Achievement Award in Pharmaceutics and Drug Delivery. He served as an Associate Professor of Radiology at Harvard Medical School before joining Northeastern University as the Chairman of the Department of Pharmaceutical Sciences./a
Book Synopsis Smart Polymeric Nano-Constructs in Drug Delivery by : Suresh P Vyas
Download or read book Smart Polymeric Nano-Constructs in Drug Delivery written by Suresh P Vyas and published by Academic Press. This book was released on 2022-11-12 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications provides a thorough discussion of the most state of the art material and polymer exploitations for the delivery of bioactive(s) as well as their current and clinical status. The book enables researchers to prepare a variety of smart drug delivery systems to investigate their properties as well as to discover their uses and applications. The novelty of this approach addresses an existing need of exhaustively understanding the potential of the materials including polymeric drug delivery systems that are smartly designed to deliver bioactive(s) into the body at targeted sites without showing side effects. The book is helpful for those in the health sector, specifically those developing nanomedicine using smart material-based nano-delivery systems. Polymers have unique co-operative properties that are not found with low-molecular-weight compounds along with their appealing physical and chemical properties, constituting the root of their success in drug delivery. Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications discusses smart and stimuli responsive polymers applicable in drug delivery, followed detailed information about various concepts and designing of polymeric novel drug delivery systems for treatment of various type of diseases, also discussing patents related to the field. The book helps readers to design and develop novel drug delivery systems based on smart materials for the effective delivery of bioactive that take advantage of recent advances in smart polymer-based strategies. It is useful to those in pharmaceutical sciences and related fields in developing new drug delivery systems. - Provides comprehensive overview of the potential role of polymeric systems in drug delivery - Explores the design, synthesis, and application of different smart material-based delivery systems - Includes fundamental and clinical applications
