Design and synthesis of chiral auxiliaries for use in asymmetric synthesis

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ISBN 13 :
Total Pages : 428 pages
Book Rating : 4.:/5 (143 download)

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Book Synopsis Design and synthesis of chiral auxiliaries for use in asymmetric synthesis by : Hwang-Hsing Chen

Download or read book Design and synthesis of chiral auxiliaries for use in asymmetric synthesis written by Hwang-Hsing Chen and published by . This book was released on 1985 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Tools for Efficient Asymmetric Synthesis [electronic Resource] : Design, Synthesis and Application of Fluorous Oxazolidinone Chiral Auxiliaries

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Publisher : University of Manitoba
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (855 download)

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Book Synopsis Tools for Efficient Asymmetric Synthesis [electronic Resource] : Design, Synthesis and Application of Fluorous Oxazolidinone Chiral Auxiliaries by : Hein, Jason Ellis

Download or read book Tools for Efficient Asymmetric Synthesis [electronic Resource] : Design, Synthesis and Application of Fluorous Oxazolidinone Chiral Auxiliaries written by Hein, Jason Ellis and published by University of Manitoba. This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluorous chiral auxiliary -- asymmetric synthesis -- organic chemistry -- oxazolidinones -- aldol reactions.

Principles and Applications of Asymmetric Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 0471465240
Total Pages : 536 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis Principles and Applications of Asymmetric Synthesis by : Guo-Qiang Lin

Download or read book Principles and Applications of Asymmetric Synthesis written by Guo-Qiang Lin and published by John Wiley & Sons. This book was released on 2003-05-29 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Asymmetric synthesis remains a challenge to practicing scientistsas the need for enantiomerically pure or enriched compoundscontinues to increase. Over the last decade, a large amount ofliterature has been published in this field. Principles andApplications of Asymmetric Synthesis consolidates and evaluates themost useful methodologies into a one-volume resource for theconvenience of practicing scientists and students. Authored by internationally renowned scientists in the field, thisreliable reference covers more than 450 reactions and includesimportant stoichiometric as well as catalytic asymmetric reactions.The first chapter reviews the basic principles, commonnomenclature, and analytical methods, and the remainder of the bookis organized according to reaction type. The text examines suchtopics as: Carbon-carbon bond formations involving carbonyls, enamines,imines, and enolates Asymmetric C-O bond formations including epoxidation,dihydroxylation, and aminohydroxylation Asymmetric synthesis using the Diels-Alder reaction and othercyclizations Applications to the total synthesis of natural products Use of enzymes in asymmetric synthesis Practicing chemists in the pharmaceutical, fine chemical, andagricultural professions as well as graduate students will findthat Principles and Applications of Asymmetric Synthesis affordscomprehensive and current coverage.

Chiral Auxiliaries and Ligands in Asymmetric Synthesis

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Publisher : Wiley-Interscience
ISBN 13 :
Total Pages : 744 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Chiral Auxiliaries and Ligands in Asymmetric Synthesis by : J. Seyden-Penne

Download or read book Chiral Auxiliaries and Ligands in Asymmetric Synthesis written by J. Seyden-Penne and published by Wiley-Interscience. This book was released on 1995-10-23 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: Table of Contents Preface Abbreviations Introduction 1 1 Enantiomerically Pure Chiral Auxiliaries 43 2 Chiral Reagents 87 3 Chiral Catalysis and Catalysts Bearing Chiral Ligands 117 4 Asymmetric Deprotonations and Protonations 143 5 Alkylations and Related Reactions 157 6 Additions to C=O and C=N Double Bonds 209 7 Additions to Carbon-Carbon Double Bonds 367 8 Additions to Double Bonds Bearing Heteroatoms. Oxidations of Sulfides and Selenides 503 9 Cycloadditions 513 10 Sigmatropic Rearrangements 593 11 Transition Metal Catalyzed Reactions 619 References 637 Index 707.

Chiral Building Blocks in Asymmetric Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 3527834192
Total Pages : 692 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Chiral Building Blocks in Asymmetric Synthesis by : Jacek Wojaczynski

Download or read book Chiral Building Blocks in Asymmetric Synthesis written by Jacek Wojaczynski and published by John Wiley & Sons. This book was released on 2022-08-05 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chiral Building Blocks in Asymmetric Synthesis A comprehensive introduction to the important classes of chiral building blocks Chirality — the asymmetric quality found in certain chemical compounds — plays an essential role in our world: chiral compounds can be found in biology, pharmaceutical compounds, agrochemicals, and fragrances. The stereoselective preparation of these complex molecular constructions constitutes a challenge. To this end, modern asymmetric synthesis utilizes a variety of valuable and efficient reagents employed as chiral auxiliaries, metal complexes and organocatalysts in stereoselective catalysis, and enantiopure reactants termed as chiral building blocks. In Chiral Building Blocks in Asymmetric Synthesis, the achievements in the fields of preparation of and applications of chiral blocks are presented. In doing so, the book comprehensively discusses the important classes of these reactants as the key for the asymmetric synthesis of chiral molecules. As such, it is an indispensable resource about synthetic methods, as well as possible modifications and transformations of important classes of chiral compounds. It also highlights the importance of their use as reactants and auxiliaries in the preparation of more sophisticated molecules or supramolecular systems. In Chiral Building Blocks in Asymmetric Synthesis readers will also find: Organization according to the most important compound classes — e.g. amino acids, BINOL and its derivatives, terpenes, and others — with an emphasis on synthesis and application A focus on the use of chiral building blocks for the preparation of bioactive compounds and supramolecular assemblies Chiral Building Blocks in Asymmetric Synthesis is a useful reference for organic chemists, catalytic chemists, chemists in industry, medicinal chemists, pharmaceutical chemists, and the libraries that support them.

Design, Synthesis and Evaluation of Chiral Auxiliaries, Ligands and Catalysts for Asymmetric Synthesis [microform]

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Publisher : Library and Archives Canada = Bibliothèque et Archives Canada
ISBN 13 :
Total Pages : 590 pages
Book Rating : 4.:/5 (243 download)

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Book Synopsis Design, Synthesis and Evaluation of Chiral Auxiliaries, Ligands and Catalysts for Asymmetric Synthesis [microform] by : Arun A. (Arun Anil) Narine

Download or read book Design, Synthesis and Evaluation of Chiral Auxiliaries, Ligands and Catalysts for Asymmetric Synthesis [microform] written by Arun A. (Arun Anil) Narine and published by Library and Archives Canada = Bibliothèque et Archives Canada. This book was released on 2004 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chirality in Drug Design and Synthesis

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Publisher : Academic Press
ISBN 13 : 1483288242
Total Pages : 264 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Chirality in Drug Design and Synthesis by : C. Brown

Download or read book Chirality in Drug Design and Synthesis written by C. Brown and published by Academic Press. This book was released on 2013-10-22 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chirality in Drug Design and Synthesis is a collection of papers that discusses the property of asymmetry in the structural and synthetic chemistry of natural products, including the significance of chirality in medicinal chemistry. These papers examine the need for the preparation and study of pure enantiomers of chiral drug substances and their mechanism of interaction with enzymes and receptors. These papers also investigate the techniques in studying these interactions, as well as analyze the methods for their synthesis in enantiomerically pure form. One paper discusses the pharmacological and pharmacokinetic analyses made that point to the differences in the activity and disposition of enantiometric pairs. Another paper reviews the implications of the neglect of stereoselectivity at the different levels during the examination process of racemic drugs. Since no general guidelines exists for the development of drugs with chiral centers, one paper suggests a case-by-case approach in evaluating the safety and efficacy of drugs, particularly as regards how isomers differ in their effects. This collection is suitable for the pharmacologist, medicinal chemists, toxicologists, mechanistic chemists and synthetic organic chemists.

Chiral Reagents for Asymmetric Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 9780470856253
Total Pages : 618 pages
Book Rating : 4.8/5 (562 download)

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Book Synopsis Chiral Reagents for Asymmetric Synthesis by : Leo A. Paquette

Download or read book Chiral Reagents for Asymmetric Synthesis written by Leo A. Paquette and published by John Wiley & Sons. This book was released on 2003-08-01 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Derived from the renowned, Encyclopedia of Reagents for Organic Synthesis (EROS), the related editors have created a new handbook which focuses on chiral reagents used in asymmetric synthesis and is designed for the chemist at the bench. This new handbook follows the same format as the Encyclopedia, including an introduction and an alphabetical arrangement of the reagents. As chiral reagents are the key for the successful asymmetric synthesis, choosing the right reagents is essential, in this handy reference the editors give details on how to prepare, store and use the reagents as well as providing key reactions to demonstrate where reagents have been successfully used. Comprehensive information on 226 reagents Covers 64 reagents which were not included in EROS All information in one easy to use volume – at an affordable price All reagents included will be added to e-EROS – please visit the site where you can gain access to over 50,000 reactions and 3,800 of the most frequently consulted reagents. Visit: www.interscience.wiley.com/eros

Design, Synthesis and Evaluation of Chiral Auxiliaries, Ligands and Catalysts for Asymmetric Synthesis

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (112 download)

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Book Synopsis Design, Synthesis and Evaluation of Chiral Auxiliaries, Ligands and Catalysts for Asymmetric Synthesis by : Arun A. Narine

Download or read book Design, Synthesis and Evaluation of Chiral Auxiliaries, Ligands and Catalysts for Asymmetric Synthesis written by Arun A. Narine and published by . This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Task definition theoretically is one of the main components of self-regulated learning because one's representation of the task directs cognitive activities such as setting goals, creating plans, and enacting those plans to create task products. To date, little research has examined students' representations of tasks or how those representations change over time. In this dissertation I characterize students' initial representations of tasks and explore factors influencing how they refine these representations over time. Fifty-eight undergraduate students taking an undergraduate instructional psychology course participated in a semester-long examination of how students constructed and refined their task understanding. The data source was a studying portfolio consisting of detailed descriptions about and reflections on strategic processes they used to complete two main writing assignments in the course: a think paper and a design project. Analyses of these data suggest students' representations of tasks varied across two dimensions: breadth and depth. In terms of breadth, students selected information from the design project description of different grain sizes. Students with greater depth not only searched and selected information from the task, but they actively assembled elements of the task and monitored how those components fit with one another. Most students set goals and created plans; however, not all goals or plans were framed in light of criteria that would theoretically foster self-regulated learning. To revise task understanding, students metacognitively monitored their processes and outcomes of learning activities, which updated information about task, cognitive, and motivational conditions. This additional information afforded students opportunity to reassess the discrepancy between the initial state and the goal state to determine next steps to reach task goals. Although students may have recognized the need to change their approaches, they often failed to engage in effective metacognitive control to adapt approaches to learning. I interpret this to indicate that control processes require not only the skill for enacting these processes but also the motivational catalyst to sustain these efforts when competing factors are present. Future research should strive to create new measures for task understanding, and to track how students' perceptions and representations of tasks influence self-regulated learning and achievement.

The resolution and use of chiral auxiliaries in asymmetric synthesis

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Publisher :
ISBN 13 :
Total Pages : 450 pages
Book Rating : 4.:/5 (222 download)

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Book Synopsis The resolution and use of chiral auxiliaries in asymmetric synthesis by : Robert Michael Lawrence

Download or read book The resolution and use of chiral auxiliaries in asymmetric synthesis written by Robert Michael Lawrence and published by . This book was released on 1988 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Design and Synthesis of Chiral Auxiliaries for Use in Carbon-carbon Bond Forming Reactions

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Publisher :
ISBN 13 :
Total Pages : 120 pages
Book Rating : 4.:/5 (841 download)

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Book Synopsis Design and Synthesis of Chiral Auxiliaries for Use in Carbon-carbon Bond Forming Reactions by : Jessica Marie Sligar

Download or read book Design and Synthesis of Chiral Auxiliaries for Use in Carbon-carbon Bond Forming Reactions written by Jessica Marie Sligar and published by . This book was released on 2003 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: A variety of chiral auxiliaries have been synthesized from derivatives of natural products (I R, 2S)-ephedrine, (L)-valine and S-methyl-(L)-cysteine. These ligands were designed for use as chiral non-transferable ligands in organocuprate reactions. Different parameters such as solvent, the use of chiral additives and copper(l) salt have been studied and compared. Enantiomeric excesses as high as 64% have been obtained.

Advanced Asymmetric Synthesis

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Publisher : Boom Koninklijke Uitgevers
ISBN 13 : 9780751400496
Total Pages : 454 pages
Book Rating : 4.4/5 (4 download)

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Book Synopsis Advanced Asymmetric Synthesis by : G.R. Stephenson

Download or read book Advanced Asymmetric Synthesis written by G.R. Stephenson and published by Boom Koninklijke Uitgevers. This book was released on 1996-06-30 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Design of asymmetric synthesis. Nonlinear effects in enantioselective synthesis - asymmetric amplification. Chiral enolates. Optically active B-ketosulfoxides in asymmetric synthesis. Chiral aminals in asymmetric synthesis. Asymmetric deprotonation reactions using enantiopure lithium amide bases. Asymmetric Diels-Alder reactions. Asymmetric oxidiation. Transition metal catalysts for asymmetric reduction. Asymmetric hydroboration. Asymmetric hydrosilylation and hydroformylation. Asymmetric conjugate addition reactions. Stereoselective transformations mediated by chiral titanium complexes. Asymmetric synthesis using enzymes and whole cells. Asymmetric palladium catalysed coupling reactions. Palladium allyl pi-complexes in asymmetric synthesis. Worked examples in asymmetric synthesis design. Stoichiometric electrophilic pi-complexes in asymmetric synthesis.

Part I, the Design and Synthesis of a Chiral Auxiliary for Use in Diels-Alder Cycloadditions and Aldol Condensation Reactions

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Publisher :
ISBN 13 :
Total Pages : 502 pages
Book Rating : 4.:/5 (395 download)

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Book Synopsis Part I, the Design and Synthesis of a Chiral Auxiliary for Use in Diels-Alder Cycloadditions and Aldol Condensation Reactions by : Michelle Ann Laci

Download or read book Part I, the Design and Synthesis of a Chiral Auxiliary for Use in Diels-Alder Cycloadditions and Aldol Condensation Reactions written by Michelle Ann Laci and published by . This book was released on 1997 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Chiral Auxiliary Design and Application. Diastereoselective Ester Enolate Alkylations. Asymmetric Synthesis of Chiral Cyclohexanes. Synthesis and Characterization of N,N'-disubstituted Diaza-14- Crown-4 Ethers

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Publisher :
ISBN 13 :
Total Pages : 126 pages
Book Rating : 4.:/5 (115 download)

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Book Synopsis Chiral Auxiliary Design and Application. Diastereoselective Ester Enolate Alkylations. Asymmetric Synthesis of Chiral Cyclohexanes. Synthesis and Characterization of N,N'-disubstituted Diaza-14- Crown-4 Ethers by : Richard E. Taylor

Download or read book Chiral Auxiliary Design and Application. Diastereoselective Ester Enolate Alkylations. Asymmetric Synthesis of Chiral Cyclohexanes. Synthesis and Characterization of N,N'-disubstituted Diaza-14- Crown-4 Ethers written by Richard E. Taylor and published by . This book was released on 1992 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Part I: the Design and Synthesis of a Chiral Auxiliary for Use in Diels-Alder Cycloaddtions and Aldol Condensation Reactions

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Publisher :
ISBN 13 : 9780591730753
Total Pages : 251 pages
Book Rating : 4.7/5 (37 download)

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Book Synopsis Part I: the Design and Synthesis of a Chiral Auxiliary for Use in Diels-Alder Cycloaddtions and Aldol Condensation Reactions by : Michelle Ann Laci

Download or read book Part I: the Design and Synthesis of a Chiral Auxiliary for Use in Diels-Alder Cycloaddtions and Aldol Condensation Reactions written by Michelle Ann Laci and published by . This book was released on 1998 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Design and Synthesis of a Novel Series of Chiral Auxiliaries

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (66 download)

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Book Synopsis Design and Synthesis of a Novel Series of Chiral Auxiliaries by : C. Louise Picken

Download or read book Design and Synthesis of a Novel Series of Chiral Auxiliaries written by C. Louise Picken and published by . This book was released on 1996 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Design and Synthesis of a Novel Series of Chiral Auxiliaries

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (66 download)

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Book Synopsis Design and Synthesis of a Novel Series of Chiral Auxiliaries by : C. Louise Picken

Download or read book Design and Synthesis of a Novel Series of Chiral Auxiliaries written by C. Louise Picken and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: