Dendritic Spines From Shape To Function

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Dendritic spines: from shape to function

Author : Nicolas Heck
Publisher : Frontiers Media SA
ISBN 13 : 2889197662
Total Pages : 237 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Dendritic spines: from shape to function by : Nicolas Heck

Download or read book Dendritic spines: from shape to function written by Nicolas Heck and published by Frontiers Media SA. This book was released on 2016-02-03 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: One fundamental requisite for a comprehensive view on brain function and cognition is the understanding of the neuronal network activity of the brain. Neurons are organized into complex networks, interconnected through synapses. The main sites for excitatory synapses in the brain are thin protrusions called dendritic spines that emerge from dendrites. Dendritic spines have a distinct morphology with a specific molecular organization. They are considered as subcellular compartments that constrain diffusion and influence signal processing by the neuron and, hence, spines are functional integrative units for which morphology and function are tightly coupled. The density of spines along the dendrite reflects the levels of connectivity within the neuronal network. Furthermore, the relevance of studying dendritic spines is emphasized by the observation that their morphology changes with synaptic plasticity and is altered in many psychiatric disorders. The present Research Topic deals with some of the most recent findings concerning dendritic spine structure and function, showing that, in order to understand how brain neuronal activity operates, these two factors should be regarded as being intrinsically linked.

Dendritic Spines

Author : Alberto A. Rasia-Filho
Publisher : Springer Nature
ISBN 13 : 3031361598
Total Pages : 511 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Dendritic Spines by : Alberto A. Rasia-Filho

Download or read book Dendritic Spines written by Alberto A. Rasia-Filho and published by Springer Nature. This book was released on 2023-12-16 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference provides detailed coverage of dendritic spines, the fascinating neuronal components that modulate synaptic transmission, development, strength, and plasticity and are involved in the function of multiple areas of the nervous system. The density, shape, and function of spines may indicate the cellular connectivity and synaptic plasticity in normal and pathological conditions. This field has undergone dramatic advances in terms of techniques and experimental findings from in vitro to in vivo data, from animal models to human neurons, and computational models using artificial intelligence. To address these cutting-edge findings, the book provides state-of-the-art, comprehensive coverage with chapters written by the leading international researchers in the field. The authors consider the multiple implications for the study of dendritic spines with broad implications in the neurosciences and related areas.

Drebrin

Author : Tomoaki Shirao
Publisher : Springer
ISBN 13 : 4431565507
Total Pages : 401 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Drebrin by : Tomoaki Shirao

Download or read book Drebrin written by Tomoaki Shirao and published by Springer. This book was released on 2017-08-31 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first comprehensive review of drebrin, which plays pivotal roles in various cellular events, via forming unique actin cytoskeletons, including synapse formation and in synaptic function. Particularly the loss of drebrin from dendritic spines is used as a marker of dementia in neurological disorders such as Alzheimer’s disease. Since drebrin was first identified by our group in 1985, many studies of drebrin have been done in various fields, including not only molecular biology, biophysics, cell biology, neuroscience, clinical studies, spermatogenesis, immunology, and cancer metastasis, but others as well. The structure of this book facilitates the understanding of the whole picture of studies on drebrin. The volume begins with a general introduction to drebrin, and then the chapters in the second part provide the basic knowledge for further understanding. The third part examines its function in the nervous system, and the fourth part discusses its function in the non-nervous system. This work will appeal to researchers who are interested in cytoskeletal dynamics at membrane-cytoskeletal interface as well as the number of them who use drebrin as a tool, such as a marker of synaptic function or a disease marker. This volume is kept as concise as possible in order to be understood by readers in diverse scientific disciplines.

Connecting Form and Function: Recent Advances in Understanding Dendrite Morphogenesis and Plasticity

Author : Quan Yuan
Publisher : Frontiers Media SA
ISBN 13 : 2889745627
Total Pages : 219 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Connecting Form and Function: Recent Advances in Understanding Dendrite Morphogenesis and Plasticity by : Quan Yuan

Download or read book Connecting Form and Function: Recent Advances in Understanding Dendrite Morphogenesis and Plasticity written by Quan Yuan and published by Frontiers Media SA. This book was released on 2022-03-03 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Dendritic Spines: from Biophysics to Neuropathology

Author : Menahem Segal
Publisher : Frontiers Media SA
ISBN 13 : 2889666336
Total Pages : 140 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Dendritic Spines: from Biophysics to Neuropathology by : Menahem Segal

Download or read book Dendritic Spines: from Biophysics to Neuropathology written by Menahem Segal and published by Frontiers Media SA. This book was released on 2021-03-26 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Theoretical Foundation of Dendritic Function

Author : Wilfrid Rall
Publisher : MIT Press
ISBN 13 : 9780262193566
Total Pages : 484 pages
Book Rating : 4.1/5 (935 download)

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Book Synopsis The Theoretical Foundation of Dendritic Function by : Wilfrid Rall

Download or read book The Theoretical Foundation of Dendritic Function written by Wilfrid Rall and published by MIT Press. This book was released on 1995 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection of fifteen previously published papers, some of them not widely available, have been carefully chosen and annotated by Rall's colleagues and other leading neuroscientists.

Neural Circuit Development and Function in the Healthy and Diseased Brain

Author : John Rubenstein
Publisher :
ISBN 13 : 9780123972675
Total Pages : 834 pages
Book Rating : 4.9/5 (726 download)

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Book Synopsis Neural Circuit Development and Function in the Healthy and Diseased Brain by : John Rubenstein

Download or read book Neural Circuit Development and Function in the Healthy and Diseased Brain written by John Rubenstein and published by . This book was released on 2013 with total page 834 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 3 offers 40 high level articles devoted mainly to anatomical and functional development of neural circuits and neural systems, as well as those that address neurodevelopmental disorders in humans and experimental organisms. Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop Features leading experts in various subfields as Section Editors and article Authors All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship Volume 3 sections include coverage of: mechanisms that control the assembly of neural circuits in specific regions of the nervous system, multiple aspects of cognitive development, and disorders of the nervous system arising through defects in neural development

Neurosteroids

Author : Hubert Vaudry
Publisher : Frontiers E-books
ISBN 13 : 2889190781
Total Pages : 476 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Neurosteroids by : Hubert Vaudry

Download or read book Neurosteroids written by Hubert Vaudry and published by Frontiers E-books. This book was released on with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thirty years ago, the group of Baulieu and colleagues discovered that certain steroid hormones were present in higher amounts in the brain than in the plasma, and also found that suppression of circulating steroids by adrenalectomy and castration did not affect the concentration of pregnenolone, dehydroepiandrosterone and their sulfate esters in the rat brain. These seminal observations led to the concept that the brain, in very much the same way as the adrenal cortex, testis, ovary and placenta, was capable of synthesizing steroids. These brain born steroids, called neurosteroids, have been found to exert a vast array of biological activities. A number of steroidogenic enzymes have now been identified in the central nervous system by immunohistochemistry and in situ hybridization, and the neuronal and hormonal mechanisms regulating the biosynthesis of neurosteroids have been partially elucidated. The aim of this Research Topic is to celebrate three decades of research on neurosteroids by gathering a bouquet of review papers and original articles from leading scientists in the flourishing field of neurosteroids.

Encyclopedia of Behavioral Neuroscience

Author :
Publisher : Elsevier
ISBN 13 : 0080453961
Total Pages : 1819 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Encyclopedia of Behavioral Neuroscience by :

Download or read book Encyclopedia of Behavioral Neuroscience written by and published by Elsevier. This book was released on 2010-06-03 with total page 1819 pages. Available in PDF, EPUB and Kindle. Book excerpt: Behavioral Neuroscientists study the behavior of animals and humans and the neurobiological and physiological processes that control it. Behavior is the ultimate function of the nervous system, and the study of it is very multidisciplinary. Disorders of behavior in humans touch millions of people’s lives significantly, and it is of paramount importance to understand pathological conditions such as addictions, anxiety, depression, schizophrenia, autism among others, in order to be able to develop new treatment possibilities. Encyclopedia of Behavioral Neuroscience is the first and only multi-volume reference to comprehensively cover the foundation knowledge in the field. This three volume work is edited by world renowned behavioral neuroscientists George F. Koob, The Scripps Research Institute, Michel Le Moal, Université Bordeaux, and Richard F. Thompson, University of Southern California and written by a premier selection of the leading scientists in their respective fields. Each section is edited by a specialist in the relevant area. The important research in all areas of Behavioral Neuroscience is covered in a total of 210 chapters on topics ranging from neuroethology and learning and memory, to behavioral disorders and psychiatric diseases. The only comprehensive Encyclopedia of Behavioral Neuroscience on the market Addresses all recent advances in the field Written and edited by an international group of leading researchers, truly representative of the behavioral neuroscience community Includes many entries on the advances in our knowledge of the neurobiological basis of complex behavioral, psychiatric, and neurological disorders Richly illustrated in full color Extensively cross referenced to serve as the go-to reference for students and researchers alike The online version features full searching, navigation, and linking functionality An essential resource for libraries serving neuroscientists, psychologists, neuropharmacologists, and psychiatrists

Dendrites

Author : Kazuo Emoto
Publisher : Springer
ISBN 13 : 4431560505
Total Pages : 608 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Dendrites by : Kazuo Emoto

Download or read book Dendrites written by Kazuo Emoto and published by Springer. This book was released on 2016-08-19 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies in human patients and animal models of disease suggest a strong correlation between defects in dendrite development and common neurological disorders such as autism. Much of this book is thus dedicated toward highlighting recent advances in our understanding of the cellular and molecular mechanisms that regulate the development and maintenance of dendrites, a crucial component of neurons. The book begins by presenting the current state of knowledge on the building blocks or cell biology of dendrites. Mechanisms that sculpt the stereotypic architecture of dendritic arbors and shape their connectivity are also discussed, along with recent work describing how dendritic organization and connectivity are perturbed in disease. A unique aspect of the book is its exploration of diverse neuronal cell types across vertebrates and invertebrates, allowing a comparison of mechanisms across distinct circuits and species. The book comprises six parts, which cover the major advances in the field: Part 1, Introduction; Part 2, Basic Biology of Dendrites; Part 3, Patterning Dendritic Architecture of Neurons and Their Populations; Part 4, Cellular and Molecular Control of Dendrite Development and Maintenance; Part 5, Synapse Formation onto Dendrites; and Part 6, Dendrites in Disease. The book offers an excellent point of entry for students interested in neuroscience, as well as for clinicians.

Encyclopedia of Neuroscience, Volume 1

Author : Larry R. Squire
Publisher : Academic Press
ISBN 13 : 0080963935
Total Pages : 12505 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Encyclopedia of Neuroscience, Volume 1 by : Larry R. Squire

Download or read book Encyclopedia of Neuroscience, Volume 1 written by Larry R. Squire and published by Academic Press. This book was released on 2009-06-12 with total page 12505 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of the Neuroscience explores all areas of the discipline in its focused entries on a wide variety of topics in neurology, neurosurgery, psychiatry and other related areas of neuroscience. Each article is written by an expert in that specific domain and peer reviewed by the advisory board before acceptance into the encyclopedia. Each article contains a glossary, introduction, a reference section, and cross-references to other related encyclopedia articles. Written at a level suitable for university undergraduates, the breadth and depth of coverage will appeal beyond undergraduates to professionals and academics in related fields.

Dendritic Spines

Author : Rafael Yuste
Publisher : MIT Press
ISBN 13 : 026254900X
Total Pages : 293 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Dendritic Spines by : Rafael Yuste

Download or read book Dendritic Spines written by Rafael Yuste and published by MIT Press. This book was released on 2023-08-22 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: A leading neurobiologist explores the fundamental function of dendritic spines in neural circuits by analyzing different aspects of their biology, including structure, development, motility, and plasticity. Most neurons in the brain are covered by dendritic spines, small protrusions that arise from dendrites, covering them like leaves on a tree. But a hundred and twenty years after spines were first described by Ramón y Cajal, their function is still unclear. Dozens of different functions have been proposed, from Cajal's idea that they enhance neuronal interconnectivity to hypotheses that spines serve as plasticity machines, neuroprotective devices, or even digital logic elements. In Dendritic Spines, leading neurobiologist Rafael Yuste attempts to solve the “spine problem,” searching for the fundamental function of spines. He does this by examining many aspects of spine biology that have fascinated him over the years, including their structure, development, motility, plasticity, biophysical properties, and calcium compartmentalization. Yuste argues that we may never understand how the brain works without understanding the specific function of spines. In this book, he offers a synthesis of the information that has been gathered on spines (much of which comes from his own studies of the mammalian cortex), linking their function with the computational logic of the neuronal circuits that use them. He argues that once viewed from the circuit perspective, all the pieces of the spine puzzle fit together nicely into a single, overarching function. Yuste connects these two topics, integrating current knowledge of spines with that of key features of the circuits in which they operate. He concludes with a speculative chapter on the computational function of spines, searching for the ultimate logic of their existence in the brain and offering a proposal that is sure to stimulate discussions and drive future research.

Bio-inspired Physiological Signal(s) and Medical Image(s) Neural Processing Systems Based on Deep Learning and Mathematical Modeling for Implementing Bio-Engineering Applications in Medical and Industrial Fields

Download Bio-inspired Physiological Signal(s) and Medical Image(s) Neural Processing Systems Based on Deep Learning and Mathematical Modeling for Implementing Bio-Engineering Applications in Medical and Industrial Fields PDF Online Free

Author : Francesco Rundo
Publisher : Frontiers Media SA
ISBN 13 : 2889719162
Total Pages : 213 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Bio-inspired Physiological Signal(s) and Medical Image(s) Neural Processing Systems Based on Deep Learning and Mathematical Modeling for Implementing Bio-Engineering Applications in Medical and Industrial Fields by : Francesco Rundo

Download or read book Bio-inspired Physiological Signal(s) and Medical Image(s) Neural Processing Systems Based on Deep Learning and Mathematical Modeling for Implementing Bio-Engineering Applications in Medical and Industrial Fields written by Francesco Rundo and published by Frontiers Media SA. This book was released on 2021-12-31 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The NEURON Book

Author : Nicholas T. Carnevale
Publisher : Cambridge University Press
ISBN 13 : 1139447831
Total Pages : 399 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis The NEURON Book by : Nicholas T. Carnevale

Download or read book The NEURON Book written by Nicholas T. Carnevale and published by Cambridge University Press. This book was released on 2006-01-12 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authoritative reference on NEURON, the simulation environment for modeling biological neurons and neural networks that enjoys wide use in the experimental and computational neuroscience communities. This book shows how to use NEURON to construct and apply empirically based models. Written primarily for neuroscience investigators, teachers, and students, it assumes no previous knowledge of computer programming or numerical methods. Readers with a background in the physical sciences or mathematics, who have some knowledge about brain cells and circuits and are interested in computational modeling, will also find it helpful. The NEURON Book covers material that ranges from the inner workings of this program, to practical considerations involved in specifying the anatomical and biophysical properties that are to be represented in models. It uses a problem-solving approach, with many working examples that readers can try for themselves.

Biology of the NMDA Receptor

Author : Antonius M. VanDongen
Publisher : CRC Press
ISBN 13 : 142004415X
Total Pages : 368 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Biology of the NMDA Receptor by : Antonius M. VanDongen

Download or read book Biology of the NMDA Receptor written by Antonius M. VanDongen and published by CRC Press. This book was released on 2008-10-29 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written

Neuroplasticity

Author : Victor Chaban
Publisher : BoD – Books on Demand
ISBN 13 : 1789231949
Total Pages : 206 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Neuroplasticity by : Victor Chaban

Download or read book Neuroplasticity written by Victor Chaban and published by BoD – Books on Demand. This book was released on 2018-06-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive and up-to-date insights into emerging research trends on neuroplasticity with current or future treatments for neurodevelopment and neurodegenerative diseases. The authors discuss structural and functional changes associated with cortical remapping, sensory substitution, synaptic and non-synaptic compensatory plasticity due to brain damage, brain training, chronic pain, meditation, music, exercise and related states. Key features include pathogenesis, and existing and new therapies together with a pharmacological and non-pharmacological approach in clinical treatment and management. The authors are established experts that contributed significantly to a better understanding of the etiology of neuroplasticity. This book is recommended to healthcare providers, clinical scientists, students and patients.

Plasticity in the Adult Brain: From Genes to Neurotherapy

Author : M.A. Hofman
Publisher : Elsevier
ISBN 13 : 008049773X
Total Pages : 496 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Plasticity in the Adult Brain: From Genes to Neurotherapy by : M.A. Hofman

Download or read book Plasticity in the Adult Brain: From Genes to Neurotherapy written by M.A. Hofman and published by Elsevier. This book was released on 2002-10-23 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decade neuronal plasticity has become a major theme of modern neurobiology, from cellular and molecular mechanisms of synapse formation in worms and insects to behavioural recovery from strokes in elderly humans. For this reason the focus of interest in the present volume of Progress in Brain Research is on the topic of neuroplasticity in mature organisms, including humans. Contributions range from neurogenesis and synaptic plasticity in the adult primate brain, to neural mechanisms of learning and memory, and the influence of environmental factors and aging on the functional potential of the central nervous system. Several contributions focus on recent developments in neural regeneration and brain repair, providing challenging evidence that the use of stem cell neurotherapy may be beneficial to humans suffering from various neurological and psychiatric diseases. This volume integrates new information on the cellular and molecular mechanisms of neuroplasticity and highlights challenging future questions in this exciting and topical area of neuroscience.