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Death Of A Gene
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Book Synopsis The Selfish Gene by : Richard Dawkins
Download or read book The Selfish Gene written by Richard Dawkins and published by Oxford University Press, USA. This book was released on 1989 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science need not be dull and bogged down by jargon, as Richard Dawkins proves in this entertaining look at evolution. The themes he takes up are the concepts of altruistic and selfish behaviour; the genetical definition of selfish interest; the evolution of aggressive behaviour; kinshiptheory; sex ratio theory; reciprocal altruism; deceit; and the natural selection of sex differences. 'Should be read, can be read by almost anyone. It describes with great skill a new face of the theory of evolution.' W.D. Hamilton, Science
Book Synopsis SIDS Sudden Infant and Early Childhood Death by : Roger W. Byard
Download or read book SIDS Sudden Infant and Early Childhood Death written by Roger W. Byard and published by . This book was released on 2018-04 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers aspects of sudden infant and early childhood death, ranging from issues with parental grief, to the most recent theories of brainstem neurotransmitters. It also deals with the changes that have occurred over time with the definitions of SIDS (sudden infant death syndrome), SUDI (sudden unexpected death in infancy) and SUDIC (sudden unexpected death in childhood). The text will be indispensable for SIDS researchers, SIDS organisations, paediatric pathologists, forensic pathologists, paediatricians and families, in addition to residents in training programs that involve paediatrics. It will also be of use to other physicians, lawyers and law enforcement officials who deal with these cases, and should be a useful addition to all medical examiner/forensic, paediatric and pathology departments, hospital and university libraries on a global scale. Given the marked changes that have occurred in the epidemiology and understanding of SIDS and sudden death in the very young over the past decade, a text such as this is very timely and is also urgently needed.
Download or read book Death of a Gene written by Gary B. Boyd and published by AuthorHouse. This book was released on 2014-04-23 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rodney Miller was just the tip of the iceberg. Festering in his tortured mind was the depravity that defined him and his progeny for generations to come. His genetic code was written to be read in the annals of history. His sister, Mary Miller, was less tortured but possessive of the same malevolent genetics. Though separated by circumstance, her offspring and his were destined to corrupt the human genome and meet in a climactic battle of evil wills. Only Divine Providence could unravel the double-helix and erase the error before irreparable damage could be done to the human race.
Book Synopsis The Neurobiological Basis of Suicide by : Yogesh Dwivedi
Download or read book The Neurobiological Basis of Suicide written by Yogesh Dwivedi and published by CRC Press. This book was released on 2012-06-25 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.
Download or read book The Family Gene written by Joselin Linder and published by HarperCollins. This book was released on 2017-03-14 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: A riveting medical mystery about a young woman’s quest to uncover the truth about her likely fatal genetic disorder that opens a window onto the exploding field of genomic medicine When Joselin Linder was in her twenties her legs suddenly started to swell. After years of misdiagnoses, doctors discovered a deadly blockage in her liver. Struggling to find an explanation for her unusual condition, Joselin compared the medical chart of her father—who had died from a mysterious disease, ten years prior—with that of an uncle who had died under similarly strange circumstances. Delving further into the past, she discovered that her great-grandmother had displayed symptoms similar to hers before her death. Clearly, this was more than a fluke. Setting out to build a more complete picture of the illness that haunted her family, Joselin approached Dr. Christine Seidman, the head of a group of world-class genetic researchers at Harvard Medical School, for help. Dr. Seidman had been working on her family’s case for twenty years and had finally confirmed that fourteen of Joselin’s relatives carried something called a private mutation—meaning that they were the first known people to experience the baffling symptoms of a brand new genetic mutation. Here, Joselin tells the story of their gene: the lives it claimed and the future of genomic medicine with the potential to save those that remain. Digging into family records and medical history, conducting interviews with relatives and friends, and reflecting on her own experiences with the Harvard doctor, Joselin pieces together the lineage of this deadly gene to write a gripping and unforgettable exploration of family, history, and love. A compelling chronicle of survival and perseverance, The Family Gene is an important story of a young woman reckoning with her father’s death, her own mortality, and her ethical obligations to herself and those closest to her.
Book Synopsis The Death Gene by : George J. Brewer
Download or read book The Death Gene written by George J. Brewer and published by Xlibris Corporation. This book was released on 2002-04-29 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: As most everyone who reads the newspapers these days will be aware, DNA technology and cloning genes (isolating and obtaining the DNA for a specific gene) is on the cutting edge of science. Almost every week a new gene is cloned, its DNA sequence determined, and its function discovered. Discoveries of genes that cause specific diseases, even some cancers (such as breast cancer), are being made on a regular basis. The gene that is discovered in the present story is, at present, fictional. It is a gene that promotes the aging process, and therefore, it promotes death. The flip side of the gene is that if its action is turned off by a new drug, as it is in the story, it stops aging and allows an unlimited life-span. Neither the discovery of such a gene, or its manipulation by a drug, are at all far-fetched. In fact, it can be anticipated that such a gene probably will be discovered sooner or later. This is a story about what happens when such a gene, and a way to turn it off, are discovered. Story Line It all started with something seemingly trivial, the interruption of the usual behavior of the pet mice in Dr. Al Grogans laboratory. A world-class physician-scientist in his mid-fifties, Grogan has been spending long evenings in his lab and office trying to solve a riddle. Why had one of his discoveries, a promising new long-acting contraceptive called DNA-C129, quit working? The unusual squeaks and sounds of protest from the mice interrupted Grogans concentration. The reason the mice are disturbed is obvious. Maria, Grogans new lab assistant, an attractive lady in her late thirties, has disturbed the mice by peering closely at them. Initially disgruntled at the interruption, Grogan nevertheless demonstrates to Maria a trick he had taught the mice. Maria asks about the age of the mice and Grogan says theyre maybe four years old, since they were part of the original DNA-C129 experiments. Maria, who has had considerable experience studying mouse aging, contradicts her boss, saying that mice of this strain simply dont live that long. In human terms, they would be the equivalent of two-hundred years old! Grogan, who now realizes he isnt very well-informed about mouse life-span, tells Maria he was probably mistaken about the age of the mice. But he knows they are really about four years old, and his mind starts churning excitedly about some of the possible effects of DNA-C129, and about the reason it may have stopped working. With this new clue, things begin to snap into place in Grogans mind. DNA-C129 had quit working when he had lost his junior partner, a younger man named Bowdler, who had been carrying out the actual experiments under Grogans general supervision. Bowdler had been killed in an auto accident. Grogan now realizes that DNA-C129 has antiaging properties, and probably owes its long-lasting effects to Bowdler doing an outlaw experiment, namely using an illegal vector (the viral-like particle that delivers the therapy DNA), one that had not been authorized by Grogan. The keys to DNA-C129 effects, including its antiaging effects, no doubt lay not only in its own innate properties, but in the vector Bowdler had used. With Bowdlers death, and with Grogan now using the standard vector, DNA-C129 had lost its properties in Grogans experiments. During the next four months the Grogan lab becomes a beehive of activity as Grogan sets out to test these ideas. As the work goes on, a romance develops between Grogan and Maria. However, Grogan is very secretive about the purpose of the experiments, even with Maria. He works for a modest-sized biotech company, in Madison, Wisconsin, called DNA Unlimited, and he doesnt trust management. He codes all the results, and mixes up the experiments in such a manner that no single technician has a complete picture of the studies and the results. During this time Grogan places regular calls to a former student, and current best friend, Kirk Starge
Book Synopsis Population Biology and Evolution by : K. Wöhrmann
Download or read book Population Biology and Evolution written by K. Wöhrmann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the papers presented at a symposium on popula tion biology sponsored by the Deutsche Forschungsgemeinschaft. It was . held at the guest house of the University of Ttibingen at Oberjoch on May 15-19, 1983. Prior to this conference a small group of European biologists had met in Berlin (June 1981) and Pavia (September 1982) to discuss re search problems on the borderline between population genetics and evolutionary ecology. From the contributions and discussions at these meetings it became evident that the unification of approaches to evolutionary problems in population genetics and evolutionary ecology has not yet been suc cessful and requires further efforts. It was the consensus that a larger symposium with international participation would be helpful to con front and discuss the different approaches to population biology in order to assess "where we are now" and "where we should be going. " As a result an organizational committee was formed (F. Christiansen, S. Jayakar, V. Loeschcke, W. Scharloo, and K. W6hrmann) to iden tify topics that seemed, at least to them, to be fruitful in tackling problems in population biology. Consequently, a number of colleagues were asked to participate in the meeting. We have divided this book into chapters corresponding to the eight topics chosen. The volume begins with the relation between genotype and phenotype and is followed by a chapter on quantitative genetics and selection in natural populations.
Download or read book The Death Gene written by Malcolm Rose and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Evolution by Gene Duplication by : Susumu Ohno
Download or read book Evolution by Gene Duplication written by Susumu Ohno and published by Springer Science & Business Media. This book was released on 2013-12-11 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is said that "necessity is the mother of invention". To be sure, wheels and pulleys were invented out of necessity by the tenacious minds of upright citi zens. Looking at the history of mankind, however, one has to add that "Ieisure is the mother of cultural improvement". Man's creative genius flourished only when his mind, freed from the worry of daily toils, was permitted to entertain apparently useless thoughts. In the same manner, one might say with regard to evolution that "natural selection mere(y tnodifted, while redundanry created". Natural selection has been extremely effective in policing alleHe mutations which arise in already existing gene loci. Because of natural selection, organisms have been able to adapt to changing environments, and by adaptive radiation many new species were created from a common ancestral form. Y et, being an effective policeman, natural selection is extremely conservative by nature. Had evolution been entirely dependent upon natural selection, from a bacterium only numerous forms of bacteria would have emerged. The creation of metazoans, vertebrates and finally mammals from unicellular organisms would have been quite impos sible, for such big leaps in evolution required the creation of new gene loci with previously nonexistent functions. Only the cistron which became redun dant was able to escape from the relentless pressure of natural selection, and by escaping, it accumulated formerly forbidden mutations to emerge as a new gene locus.
Download or read book The Last Chapter written by Gene Amole and published by Big Earth Publishing. This book was released on 2002 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Denver's beloved columnist Gene Amole stunned readers of the Rocky Mountain News in October 2001 when he announced in his column that he was dying. He passed away six months later, just shy of his 79th birthday. This book presents Amole's powerful, poignant, and first-person account of his last days.
Download or read book The Creative Gene written by Hideo Kojima and published by VIZ Media LLC. This book was released on 2021-10-19 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ever since he was a child, Metal Gear Solid and Death Stranding creator Hideo Kojima was a voracious consumer of movies, music, and books. They ignited his passion for stories and storytelling, and the results can be seen in his groundbreaking, iconic video games. Now the head of independent studio Kojima Productions, Kojima’s enthusiasm for entertainment media has never waned. This collection of essays explores some of the inspirations behind one of the titans of the video game industry, and offers an exclusive insight into one of the brightest minds in pop culture. -- VIZ Media
Download or read book The Gene written by Siddhartha Mukherjee and published by Simon and Schuster. This book was released on 2016-05-17 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).
Download or read book Epigenetics written by Joel D. Wallach and published by SelectBooks, Inc.. This book was released on 2014-05 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHAT IS EPIGENETICS? Epigenetics is an emerging field of science that studies alterations in gene expression caused by factors other than changes in the DNA sequence. Epigenetics: The Death of the Genetic Theory of Disease Transmission is the result of decades of research and its findings that could be as critical to our understanding of human health as Pasteur’s research in bacteriology. Dr. Joel “Doc” Wallach has dedicated his life work to identifying connections between certain nutritional deficiencies and a range of maladies, formerly thought to be hereditary, including Cystic Fibrosis and Muscular Dystrophy. This nexus between nutrition and so-called genetic disease has been observed in both humans and primates, and it is the central theme of Epigenetics. To bring us Epigenetics, Wallach has teamed with noted scholars Dr. Ma Lan and Dr. Gerhard N. Schrauzer. Their collective expertise gives this book its far reaching perspective. Epigenetics is of vital importance to anyone who wants real knowledge about how the human body functions, and it provides a path for better health. Epigentics dispels the dogma and misinformation propagated by medical institutions and doctors resistant to change. Epigenetics is the beginning of a new era of well-being on this planet.
Book Synopsis Health Effects of Exposure to Low Levels of Ionizing Radiation by : National Research Council
Download or read book Health Effects of Exposure to Low Levels of Ionizing Radiation written by National Research Council and published by National Academies. This book was released on 1990-02-01 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.
Download or read book Genome written by Matt Ridley and published by Harper Collins. This book was released on 2013-03-26 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Ridley leaps from chromosome to chromosome in a handy summation of our ever increasing understanding of the roles that genes play in disease, behavior, sexual differences, and even intelligence. . . . . He addresses not only the ethical quandaries faced by contemporary scientists but the reductionist danger in equating inheritability with inevitability.” — The New Yorker The genome's been mapped. But what does it mean? Matt Ridley’s Genome is the book that explains it all: what it is, how it works, and what it portends for the future Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life. Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.
Download or read book Sex and Death written by Kim Sterelny and published by University of Chicago Press. This book was released on 1999-06-15 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this introduction to philosophy of biology, Kim Sterelny and Paul E. Griffiths present both the science and the philosophical context necessary for a critical understanding of the debates shaping biology at the end of the 20th century.
Book Synopsis Essays Upon Heredity and Kindred Biological Problems by : August Weismann
Download or read book Essays Upon Heredity and Kindred Biological Problems written by August Weismann and published by . This book was released on 1891 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt:
