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Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sarah Graves
Publisher : Bantam
ISBN 13 : 0553807900
Total Pages : 257 pages
Book Rating : 4.5/5 (538 download)
Download or read book Dead Level written by Sarah Graves and published by Bantam. This book was released on 2012 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Driving deep into the woods to her husband's cottage with her best friend, Ellie White, in tow, Jakes knows she has a challenging week ahead of her.
Author : Burkhard Madea
Publisher : CRC Press
ISBN 13 : 1444181777
Total Pages : 292 pages
Book Rating : 4.4/5 (441 download)
Download or read book Estimation of the Time Since Death written by Burkhard Madea and published by CRC Press. This book was released on 2015-09-08 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Estimation of the Time Since Death remains the foremost authoritative book on scientifically calculating the estimated time of death postmortem. Building on the success of previous editions which covered the early postmortem period, this new edition also covers the later postmortem period including putrefactive changes, entomology, and postmortem r
Author : Fumio Hanaoka
Publisher : Springer
ISBN 13 : 443155873X
Total Pages : 548 pages
Book Rating : 4.4/5 (315 download)
Download or read book DNA Replication, Recombination, and Repair written by Fumio Hanaoka and published by Springer. This book was released on 2016-01-22 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the "3Rs") and the related processes, with special consciousness of their biological and clinical consequences. The 3Rs are fundamental molecular mechanisms for organisms to maintain and sometimes intentionally alter genetic information. DNA replication, recombination, and repair, individually, have been important subjects of molecular biology since its emergence, but we have recently become aware that the 3Rs are actually much more intimately related to one another than we used to realize. Furthermore, the 3R research fields have been growing even more interdisciplinary, with better understanding of molecular mechanisms underlying other important processes, such as chromosome structures and functions, cell cycle and checkpoints, transcriptional and epigenetic regulation, and so on. This book comprises 7 parts and 21 chapters: Part 1 (Chapters 1–3), DNA Replication; Part 2 (Chapters 4–6), DNA Recombination; Part 3 (Chapters 7–9), DNA Repair; Part 4 (Chapters 10–13), Genome Instability and Mutagenesis; Part 5 (Chapters 14–15), Chromosome Dynamics and Functions; Part 6 (Chapters 16–18), Cell Cycle and Checkpoints; Part 7 (Chapters 19–21), Interplay with Transcription and Epigenetic Regulation. This volume should attract the great interest of graduate students, postdoctoral fellows, and senior scientists in broad research fields of basic molecular biology, not only the core 3Rs, but also the various related fields (chromosome, cell cycle, transcription, epigenetics, and similar areas). Additionally, researchers in neurological sciences, developmental biology, immunology, evolutionary biology, and many other fields will find this book valuable.
Author : Francisco Martínez
Publisher : Berghahn Books
ISBN 13 : 1789203325
Total Pages : 339 pages
Book Rating : 4.7/5 (892 download)
Download or read book Repair, Brokenness, Breakthrough written by Francisco Martínez and published by Berghahn Books. This book was released on 2019-09-01 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exploring some of the ways in which repair practices and perceptions of brokenness vary culturally, Repair, Brokenness, Breakthrough argues that repair is both a process and also a consequence which is sought out—an attempt to extend the life of things as well as an answer to failures, gaps, wrongdoings, and leftovers. This volume develops an open-ended combination of empirical and theoretical questions including: What does it mean to claim that something is broken? At what point is something broken repairable? What are the social relationships that take place around repair? And how much tolerance for failure do our societies have?
Author : Lois Peterson
Publisher : Orca Book Publishers
ISBN 13 : 1554698197
Total Pages : 129 pages
Book Rating : 4.5/5 (546 download)
Download or read book Beyond Repair written by Lois Peterson and published by Orca Book Publishers. This book was released on 2011-04-01 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: Key Selling Points New, enhanced features (dyslexia-friendly font, cream paper, larger trim size) to increase reading accessibility for dyslexic and other striving readers.
Author : Drew Gilpin Faust
Publisher : Vintage
ISBN 13 : 0375703837
Total Pages : 385 pages
Book Rating : 4.3/5 (757 download)
Download or read book This Republic of Suffering written by Drew Gilpin Faust and published by Vintage. This book was released on 2009-01-06 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: NATIONAL BESTSELLER • NATIONAL BOOK AWARD FINALIST • An "extraordinary ... profoundly moving" history (The New York Times Book Review) of the American Civil War that reveals the ways that death on such a scale changed not only individual lives but the life of the nation. An estiated 750,000 soldiers lost their lives in the American Civil War. An equivalent proportion of today's population would be seven and a half million. In This Republic of Suffering, Drew Gilpin Faust describes how the survivors managed on a practical level and how a deeply religious culture struggled to reconcile the unprecedented carnage with its belief in a benevolent God. Throughout, the voices of soldiers and their families, of statesmen, generals, preachers, poets, surgeons, nurses, northerners and southerners come together to give us a vivid understanding of the Civil War's most fundamental and widely shared reality. With a new introduction by the author, and a new foreword by Mike Mullen, 17th Chairman of the Joint Chiefs of Staff.
Author : Zahra Zakeri
Publisher :
ISBN 13 :
Total Pages : 236 pages
Book Rating : 4.F/5 ( download)
Download or read book Mechanisms of Cell Death written by Zahra Zakeri and published by . This book was released on 1999 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contains papers from a July 1998 conference held at the Queens College Campus of the City University of New York. Papers are arranged in sections on mechanisms and general considerations, programmed (developmental) cell death, and cell death and pathological and clinical situations. Specific topics
Author : Robert Vink
Publisher : University of Adelaide Press
ISBN 13 : 0987073052
Total Pages : 354 pages
Book Rating : 4.9/5 (87 download)
Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Author : Han-Ming Shen
Publisher : Springer Science & Business Media
ISBN 13 : 1461482208
Total Pages : 402 pages
Book Rating : 4.4/5 (614 download)
Download or read book Necrotic Cell Death written by Han-Ming Shen and published by Springer Science & Business Media. This book was released on 2014-03-29 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Starting with discussion of basic concepts and the molecular mechanisms of necrosis, this book looks first at several forms of necrotic cell death that have been identified, including necroptosis, autophagic cell death, and PARP-mediated cell death. As necrotic cell death is increasingly known to play a critical role in many physiological processes, the next chapters discuss its effect on metabolism, inflammation, immunity, and development. Necrotic cell death is closely implicated in human diseases like cancer, so the next chapters examine its relevance to human diseases, and final chapters cover methodologies for measuring necrosis. This book presents comprehensive coverage of necrosis from recognized experts from leading academic and medical institutions around the world. In contrast to apoptosis, well-defined as a form of programmed cell death, necrosis used to be considered as accidental (i.e., non-programmed) cell death, usually in response to a severe injury. Accumulating evidence now suggests, however, that necrosis is also programmed and controlled by distinctive "death machinery" in response to various stimuli like oxidative stress or DNA damage.
Author : Sarah Graves
Publisher : Bantam
ISBN 13 : 0307490149
Total Pages : 322 pages
Book Rating : 4.3/5 (74 download)
Download or read book Repair to Her Grave written by Sarah Graves and published by Bantam. This book was released on 2008-12-10 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Home repair can be murder. Jacobia Tiptree and her teenage son are used to their Eastport, Maine, home attracting more than its share of houseguests. This year Jake is hoping the plaster dust will keep them away while she finally gets her gem of a fixer-upper into shape — from doorknobs and chandeliers to leaky pipes to ghostly phenomena. But when the charming and mysterious Jonathan Raines appears on her doorstep — and then just as suddenly disappears — remodeling the house becomes the least of Jake’s problems. Could Jonathan’s disappearance have something to do with his quest for a cursed violin — the one that local legend says was hidden by a long-ago owner of Jake’s house before he too vanished without a trace? Soon Jonathan’s grief-stricken girlfriend arrives downeast, and Jake needs to strip Eastport’s past of its idyllic veneer — before a killer paints her very dead indeed!
Author : Belton Y. Cooper
Publisher : Presidio Press
ISBN 13 : 0307415007
Total Pages : 394 pages
Book Rating : 4.3/5 (74 download)
Download or read book Death Traps written by Belton Y. Cooper and published by Presidio Press. This book was released on 2007-12-18 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: “An important contribution to the history of World War II . . . I have never before been able to learn so much about maintenance methods of an armored division, with precise details that underline the importance of the work, along with descriptions of how the job was done.”—Russell F. Weigley, author of Eisenhower’s Lieutenants “Cooper saw more of the war than most junior officers, and he writes about it better than almost anyone. . . . His stories are vivid, enlightening, full of life—and of pain, sorrow, horror, and triumph.”—Stephen E. Ambrose, from his Foreword “In a down-to-earth style, Death Traps tells the compelling story of one man’s assignment to the famous 3rd Armored Division that spearheaded the American advance from Normandy into Germany. Cooper served as an ordnance officer with the forward elements and was responsible for coordinating the recovery and repair of damaged American tanks. This was a dangerous job that often required him to travel alone through enemy territory, and the author recalls his service with pride, downplaying his role in the vast effort that kept the American forces well equipped and supplied. . . . [Readers] will be left with an indelible impression of the importance of the support troops and how dependent combat forces were on them.”—Library Journal “As an alumnus of the 3rd, I eagerly awaited this book’s coming out since I heard of its release . . . and the wait and the book have both been worth it. . . . Cooper is a very polished writer, and the book is very readable. But there is a certain quality of ‘you are there’ many other memoirs do not seem to have. . . . Nothing in recent times—ridgerunning in Korea, firebases in Vietnam, or even the one hundred hours of Desert Storm—pressed the ingenuity and resolve of American troops . . . like WWII. This book lays it out better than any other recent effort, and should be part of the library of any contemporary warrior.”—Stephen Sewell, Armor Magazine “Cooper’s writing and recall of harrowing events is superb and engrossing. Highly recommended.”—Robert A. Lynn, The Stars and Stripes “This detailed story will become a classic of WWII history and required reading for anyone interested in armored warfare.”—Publishers Weekly (starred review) “[Death Traps] fills a critical gap in WWII literature. . . . It’s a truly unique and valuable work.”—G.I. Journal
Author : American Bar Association. House of Delegates
Publisher : American Bar Association
ISBN 13 : 9781590318737
Total Pages : 216 pages
Book Rating : 4.3/5 (187 download)
Download or read book Model Rules of Professional Conduct written by American Bar Association. House of Delegates and published by American Bar Association. This book was released on 2007 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Model Rules of Professional Conduct provides an up-to-date resource for information on legal ethics. Federal, state and local courts in all jurisdictions look to the Rules for guidance in solving lawyer malpractice cases, disciplinary actions, disqualification issues, sanctions questions and much more. In this volume, black-letter Rules of Professional Conduct are followed by numbered Comments that explain each Rule's purpose and provide suggestions for its practical application. The Rules will help you identify proper conduct in a variety of given situations, review those instances where discretionary action is possible, and define the nature of the relationship between you and your clients, colleagues and the courts.
Author : Richard A. Lockshin
Publisher : Wiley-Liss
ISBN 13 :
Total Pages : 536 pages
Book Rating : 4.3/5 ( download)
Download or read book When Cells Die written by Richard A. Lockshin and published by Wiley-Liss. This book was released on 1998-04-13 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: When Cells Die A Comprehensive Evaluation of Apoptosis and Programmed Cell Death Edited by Richard A. Lockshin, Zahra Zakeri, and Jonathan L. Tilly Cell death is fast becoming one of the most dynamic areas of biological research -involving as it does the study of apoptosis and programmed cell death and the role these phenomena play in development and homeostasis on the one hand, and aging and disease on the other. The profound implications for medicine and agriculture from the manipulation of these processes have spawned a deluge of research papers, articles, approaches, and methods -making it difficult for scientists to get an overview of the field. When Cells Die establishes a coherent framework for the study of cell death -cutting across viewpoints and disciplines and consolidating disparate research efforts. Leading international researchers describe a wide range of topics, including evaluation methods for programmed cell death and apoptosis in numerous tissues and circumstances; genetic mechanism, signal transduction, and observed manifestations of physiological cell death; model systems ranging from nematodes to humans; relevant work in cancer research, AIDS, immune disorders, fertility, eye disease, and Alzheimer's disease; and more. Written to provide an in-depth overview of cell death, the book is divided into five major parts: * The phenomenon of cell death * Themes and approaches to cell death * Cell death where mitosis is high and evanescence is desirable * Cell death in long-lived cells * The clinical relevance of apoptosis. When Cells Die offers a comprehensive introduction to an intriguing discipline, insight into areas in need of exploration, and information on new techniques and therapeutic applications -all supported with diagrams and flowcharts and a fully cross-referenced and indexed text. It is important reading for anyone working in cell and developmental biology, neuroscience, immunology, cancer research, and virology. It is also useful for advanced undergraduate and graduate-level students, postdoctoral fellows, and researchers just entering the field.
Author : Alma Balestrazzi
Publisher : Frontiers Media SA
ISBN 13 : 2889198200
Total Pages : 131 pages
Book Rating : 4.8/5 (891 download)
Download or read book Maintenance of Genome Integrity: DNA Damage Sensing, Signaling, Repair and Replication in Plants written by Alma Balestrazzi and published by Frontiers Media SA. This book was released on 2016-05-06 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental stresses and metabolic by-products can severely affect the integrity of genetic information by inducing DNA damage and impairing genome stability. As a consequence, plant growth and productivity are irreversibly compromised. To overcome genotoxic injury, plants have evolved complex strategies relying on a highly efficient repair machinery that responds to sophisticated damage perception/signaling networks. The DNA damage signaling network contains several key components: DNA damage sensors, signal transducers, mediators, and effectors. Most of these components are common to other eukaryotes but some features are unique to the plant kingdom. ATM and ATR are well-conserved members of PIKK family, which amplify and transduce signals to downstream effectors. ATM primarily responds to DNA double strand breaks while ATR responds to various forms of DNA damage. The signals from the activated transducer kinases are transmitted to the downstream cell-cycle regulators, such as CHK1, CHK2, and p53 in many eukaryotes. However, plants have no homologue of CHK1, CHK2 nor p53. The finding of Arabidopsis transcription factor SOG1 that seems functionally but not structurally similar to p53 suggests that plants have developed unique cell cycle regulation mechanism. The double strand break repair, recombination repair, postreplication repair, and lesion bypass, have been investigated in several plants. The DNA double strand break, a most critical damage for organisms are repaired non-homologous end joining (NHEJ) or homologous recombination (HR) pathway. Damage on template DNA makes replication stall, which is processed by translesion synthesis (TLS) or error-free postreplication repair (PPR) pathway. Deletion of the error-prone TLS polymerase reduces mutation frequencies, suggesting PPR maintains the stalled replication fork when TLS is not available. Unveiling the regulation networks among these multiple pathways would be the next challenge to be completed. Some intriguing issues have been disclosed such as the cross-talk between DNA repair, senescence and pathogen response and the involvement of non-coding RNAs in global genome stability. Several studies have highlighted the essential contribution of chromatin remodeling in DNA repair DNA damage sensing, signaling and repair have been investigated in relation to environmental stresses, seed quality issues, mutation breeding in both model and crop plants and all these studies strengthen the idea that components of the plant response to genotoxic stress might represent tools to improve stress tolerance and field performance. This focus issue gives researchers the opportunity to gather and interact by providing Mini-Reviews, Commentaries, Opinions, Original Research and Method articles which describe the most recent advances and future perspectives in the field of DNA damage sensing, signaling and repair in plants. A comprehensive overview of the current progresses dealing with the genotoxic stress response in plants will be provided looking at cellular and molecular level with multidisciplinary approaches. This will hopefully bring together valuable information for both plant biotechnologists and breeders.
Author : Ioly Kotta-Loizou
Publisher : Springer
ISBN 13 : 9783030765736
Total Pages : 0 pages
Book Rating : 4.7/5 (657 download)
Download or read book RNA Damage and Repair written by Ioly Kotta-Loizou and published by Springer. This book was released on 2022-07-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ribonucleic acid (RNA) is a macromolecule that plays a central role in cell physiology: RNA molecules act as intermediates between the deoxyribonucleic acid (DNA), where genetic information is stored, and proteins, which perform the necessary functions within the cell. Traditionally, the structural and functional properties of RNA are closely linked to gene expression. However, RNA-based enzymes, called ribozymes, are also involved in catalysis and small RNAs regulate key cellular processes, such as cell growth, division, differentiation, aging and death. RNA is a sensitive macromolecule that can be easily damaged by environmental conditions (ultraviolet radiation, oxidative stress) and biological factors (ribonucleases, ribotoxins, CRISPR-Cas systems). Therefore, cells have developed mechanisms to protect and/or repair RNA molecules. This book presents an overview of the biology of RNA damage, protection and repair in prokaryotes and eukaryotes. Individual chapters cover the expression regulation, enzymology and physiological role of such systems, and link them to important human diseases such as cancer and degenerative diseases.
Author : Larry D. Nooden
Publisher : Elsevier
ISBN 13 : 0080492088
Total Pages : 419 pages
Book Rating : 4.0/5 (84 download)
Download or read book Plant Cell Death Processes written by Larry D. Nooden and published by Elsevier. This book was released on 2003-12-09 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Programmed cell death is a common pattern of growth and development in both animals and plants. However, programmed cell death and related processes are not as generally recognized as central to plant growth. This is changing fast and is becoming more of a focus of intensive research. This edited work will bring under one cover recent reviews of programmed cell death, apoptosis and senescence.Summaries of the myriad aspects of cell death in plantsDiscussion of the broadest implications of these disparite resultsA unification of fields where there has been no cross talkEnables easy entry into diverse but related lines of research
