De la qualification d'une installation de lyophilisation à la validation du procédé

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Publisher :
ISBN 13 :
Total Pages : 322 pages
Book Rating : 4.:/5 (493 download)

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Book Synopsis De la qualification d'une installation de lyophilisation à la validation du procédé by : Benoit Moreau

Download or read book De la qualification d'une installation de lyophilisation à la validation du procédé written by Benoit Moreau and published by . This book was released on 2006 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: L'administration de préparations pharmaceutiques par voie parentérale s'est développée au XIXème siècle, suite aux découvertes de Pasteur qui ont conduit à la stérilisation des préparations injectables. Parmi ces préparations, les lyophilisats injectables sont des poudres stériles, réparties en doses unitaires, lesquelles après reconstitution sous forme liquide, sont destinées à être injectées ou perfusées. La lyophilisation, procédé utilisé pour la fabrication de cette forme galénique, est une opération de séchage qui vise à limiter au maximum les altérations de substances ou principes actifs fragiles en solution. Le procédé de lyophilisation est complexe et nécessite une maîtrise de tous les paramètres physiques et environnementaux afin de garantir la qualité du produit fini. Les contrôles effectués sur le produit en fin de fabrication ne suffisent pas à garantir l'obtention de la qualité requise. Dans ce but, la validation du procédé de fabrication permet d'apporter les preuves documentées que ce procédé permet d'obtenir, de façon reproductible, un produit répondant aux spécifications et aux critères de qualité définis par les BPF. Ce mémoire a pour objet de présenter la qualification d'une installation de lyophilisation et la démarche de validation du procédé de fabrication d'un lyophilisat injectable au moyens de protocoles issues de situations réelles et présentés sous formes de modes opératoires.

Root Ecology

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540001850
Total Pages : 424 pages
Book Rating : 4.0/5 (18 download)

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Book Synopsis Root Ecology by : Hans de Kroon

Download or read book Root Ecology written by Hans de Kroon and published by Springer Science & Business Media. This book was released on 2003-05-21 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the course of evolution, a great variety of root systems have learned to overcome the many physical, biochemical and biological problems brought about by soil. This development has made them a fascinating object of scientific study. This volume gives an overview of how roots have adapted to the soil environment and which roles they play in the soil ecosystem. The text describes the form and function of roots, their temporal and spatial distribution, and their turnover rate in various ecosystems. Subsequently, a physiological background is provided for basic functions, such as carbon acquisition, water and solute movement, and for their responses to three major abiotic stresses, i.e. hard soil structure, drought and flooding. The volume concludes with the interactions of roots with other organisms of the complex soil ecosystem, including symbiosis, competition, and the function of roots as a food source.

Public Assistance Program and Policy Guide

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Publisher : Independently Published
ISBN 13 : 9781097219360
Total Pages : 220 pages
Book Rating : 4.2/5 (193 download)

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Book Synopsis Public Assistance Program and Policy Guide by : Fema

Download or read book Public Assistance Program and Policy Guide written by Fema and published by Independently Published. This book was released on 2019-05-06 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: April 2018 Full COLOR 8 1/2 by 11 inches The Public Assistance Program and Policy Guide provides an overview of the Presidential declaration process, the purpose of the Public Assistance (PA) Program, and the authoritiesauthorizing the assistance that the Federal Emergency Management Agency provides under the PA Program. It provides PA policy language to guide eligibility determinations. Overarching eligibility requirements are presented first and are not reiterated for each topic. It provides a synopsis of the PA Program implementation process beginning with pre-declaration activities and continuing through closeout of the PA Program award. When a State, Territorial, or Indian Tribal Government determines that an incident may exceed State, Territorial, Indian Tribal, and local government capabilities to respond, it requests a joint Preliminary Damage Assessment (PDA) with the Federal Emergency Management Agency (FEMA). Federal, State, Territorial, Indian Tribal, local government, and certain private nonprofit (PNP) organization officials work together to estimate and document the impact and magnitude of the incident. Why buy a book you can download for free? We print the paperback book so you don't have to. First you gotta find a good clean (legible) copy and make sure it's the latest version (not always easy). Some documents found on the web are missing some pages or the image quality is so poor, they are difficult to read. If you find a good copy, you could print it using a network printer you share with 100 other people (typically its either out of paper or toner). If it's just a 10-page document, no problem, but if it's 250-pages, you will need to punch 3 holes in all those pages and put it in a 3-ring binder. Takes at least an hour. It's much more cost-effective to just order the bound paperback from Amazon.com This book includes original commentary which is copyright material. Note that government documents are in the public domain. We print these paperbacks as a service so you don't have to. The books are compact, tightly-bound paperback, full-size (8 1/2 by 11 inches), with large text and glossy covers. 4th Watch Publishing Co. is a HUBZONE SDVOSB. https: //usgovpub.com Buy the paperback from Amazon and get Kindle eBook FREE using MATCHBOOK. go to https: //usgovpub.com to learn how

The UNESCO Training Manual for the Protection of the Underwater Cultural Heritage in Latin America and the Caribbean

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Publisher : UNESCO Publishing
ISBN 13 : 9231004271
Total Pages : 517 pages
Book Rating : 4.2/5 (31 download)

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Book Synopsis The UNESCO Training Manual for the Protection of the Underwater Cultural Heritage in Latin America and the Caribbean by : Netherlands. Ministry of Education, Culture and Science. Cultural Heritage Agency

Download or read book The UNESCO Training Manual for the Protection of the Underwater Cultural Heritage in Latin America and the Caribbean written by Netherlands. Ministry of Education, Culture and Science. Cultural Heritage Agency and published by UNESCO Publishing. This book was released on 2021-03-10 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Good beekeeping practices for sustainable apiculture

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Publisher : Food & Agriculture Org.
ISBN 13 : 9251346127
Total Pages : 262 pages
Book Rating : 4.2/5 (513 download)

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Book Synopsis Good beekeeping practices for sustainable apiculture by : Food and Agriculture Organization of the United Nations

Download or read book Good beekeeping practices for sustainable apiculture written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org.. This book was released on 2021-09-21 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bees provide a critical link in the maintenance of ecosystems, pollination. They play a major role in maintaining biodiversity, ensuring the survival of many plants, enhancing forest regeneration, providing sustainability and adaptation to climate change and improving the quality and quantity of agricultural production systems. In fact, close to 75 percent of the world’s crops that produce fruits and seeds for human consumption depend, at least in part, on pollinators for sustained production, yield and quality. Beekeeping, also called apiculture, refers to all activities concerned with the practical management of social bee species. These guidelines aim to provide useful information and suggestions for a sustainable management of bees around the world, which can then be applied to project development and implementation.

Organic Micropollutants in the Aquatic Environment

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Publisher : Springer Science & Business Media
ISBN 13 : 9401133565
Total Pages : 545 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Organic Micropollutants in the Aquatic Environment by : G. Angeletti

Download or read book Organic Micropollutants in the Aquatic Environment written by G. Angeletti and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 10 years after the "First European Symposium on Organic Micropollutants in the Aquatic Environment", the "Sixth Symposium" was held in Lisbon (Portugal) from 22 to 24 May 1990. The Symposium was organised within the framework of the Concerted Action COST 641 * which is included in the Fourth R&D Programme on the Environment of the Commission of the European Communities expiring at the end of 1990. After restructuring the Concerted Action in 1984, particular attention has been devoted to fate and transformation of organic micropollutants in the aquatic environment. Therefore, a major aim of the Symposium was to review current studies and progress in these areas, besides more general aspects related to analytical methodologies and behaviour of pollutants during water treatment processes. This volume contains the plenary papers presented in the following sessions at the Symposium: - Multidisciplinary studies - Partitioning of organic micropollutants in the aquatic environment - Novel analytical techniques in environmental chemistry - Monitoring micropollutant - Degradation of organic micropollutants during field conditions - Reclamation of polluted ground water - Chemical and photochemical oxidation - Future of environmental chemistry. In addition, extended versions of posters are included, covering the four topics which are dealt within the four Working Parties forming the structure of the Concerted Action: 1. Analytical methodologies 2. Transport and distribution 3. Transformation reactions 4. Water treatment. We believe that the Proceedings give a good overview of current activities in these fields of research in Europe.

Science and Technology in Historic Preservation

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Publisher : Springer Science & Business Media
ISBN 13 : 146154145X
Total Pages : 404 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Science and Technology in Historic Preservation by : Ray A. Williamson

Download or read book Science and Technology in Historic Preservation written by Ray A. Williamson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technology transfer has played an increasingly important role in historic preservation during the latter half of the twentieth century, a situation attested to by the undertaking of an important congressional study in 1986 that assessed the role of federal agencies in the field. In this book leading researchers update the earlier findings and contribute state-of-the-art reviews and evaluations of technological progress in their areas of expertise.

Knowledge Representation and the Semantics of Natural Language

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Publisher : Springer Science & Business Media
ISBN 13 : 3540299661
Total Pages : 652 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Knowledge Representation and the Semantics of Natural Language by : Hermann Helbig

Download or read book Knowledge Representation and the Semantics of Natural Language written by Hermann Helbig and published by Springer Science & Business Media. This book was released on 2005-12-19 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Language is not only the most important means of communication between human beings, it is also used over historical periods for the pres- vation of cultural achievements and their transmission from one generation to the other. During the last few decades, the ?ood of digitalized information has been growing tremendously. This tendency will continue with the globali- tion of information societies and with the growing importance of national and international computer networks. This is one reason why the theoretical und- standing and the automated treatment of communication processes based on natural language have such a decisive social and economic impact. In this c- text, the semantic representation of knowledge originally formulated in natural language plays a central part, because it connects all components of natural language processing systems, be they the automatic understanding of natural language (analysis), the rational reasoning over knowledge bases, or the g- eration of natural language expressions from formal representations. This book presents a method for the semantic representation of natural l- guage expressions (texts, sentences, phrases, etc. ) which can be used as a u- versal knowledge representation paradigm in the human sciences, like lingu- tics, cognitive psychology, or philosophy of language, as well as in com- tational linguistics and in arti?cial intelligence. It is also an attempt to close the gap between these disciplines, which to a large extent are still working separately.

Water & Heritage

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ISBN 13 : 9789088903861
Total Pages : 434 pages
Book Rating : 4.9/5 (38 download)

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Book Synopsis Water & Heritage by : Willem Willems

Download or read book Water & Heritage written by Willem Willems and published by . This book was released on 2017-01-15 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Water is vital for life, and its availability has been a concern for mankind throughout the ages. Its presence has always been ascertained in a variety of ways and the development of human society everywhere is connected with various forms of water management. Man also needed to manage water to find protection from its dangers and the need for that is increasing. In the coming decades, the impact of climate change is expected to intensify floods and droughts, affect groundwater resources, raise sea levels, increase pollution and enhance the frequency and magnitude of disasters. Societies around the world are challenged to adapt to these threats to ensure water security, economic prosperity and environmental and cultural sustainability. This book deals with the heritage of water management and the use that was made of water, as well as the impact of water management on heritage. An example of the former may be an ancient irrigation system in the Filipines or in the Middle East that still functions today, while the latter may reflect the importance of maintaining groundwater levels for the preservation of organic remains on archaeological sites or of wooden piles underneath standing buildings. In either case the papers in this book reflect the dynamic nature of water, and hence the equally dynamic relation between water management and heritage. This publication follows up on a Heritage and Water conference in Amsterdam, the first of its kind. Its main purpose is to credibly present the importance and value of heritage and historical experience for water and sustainable development, and vice versa, present the importance of water management for the protection of heritage. It presents evolving insights and concepts about Water and about Heritage from a variety of disciplines, policy and public perspectives illustrated with cases studies and aims to connect decision makers with experts such as engineers, archaeologists, historians, geographers, ecologist and landscape architects

Stable Isotope Techniques in the Study of Biological Processes and Functioning of Ecosystems

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Publisher : Springer Science & Business Media
ISBN 13 : 9780792370789
Total Pages : 312 pages
Book Rating : 4.3/5 (77 download)

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Book Synopsis Stable Isotope Techniques in the Study of Biological Processes and Functioning of Ecosystems by : M.J. Unkovich

Download or read book Stable Isotope Techniques in the Study of Biological Processes and Functioning of Ecosystems written by M.J. Unkovich and published by Springer Science & Business Media. This book was released on 2001-07-31 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has a very strong practical orientation, telling readers what methodologies are available using stable isotopes, how studies should be designed and executed to maximise effectiveness and incisiveness in terms of data obtained and outcomes in terms of understanding events and processes in plant and ecosystem functioning. The readership is very much aimed toward postgraduates with good knowledge of general biological principles and underlying chemical and physical processes. Pre-existing knowledge of or experience in application and assay of stable isotopes is not required. The stable isotope research field is one of the most rapidly growing areas of ecophysiology and techniques using stable isotopes comprise an ever increasing component of research programs of university postgraduates and a wide range of agencies conducting environmental monitoring and rehabilitation programs. The book is tailor-made for such an audience.

Lamiaceae Species

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Publisher : MDPI
ISBN 13 : 3039284185
Total Pages : 140 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Lamiaceae Species by : Milan Stankovic

Download or read book Lamiaceae Species written by Milan Stankovic and published by MDPI. This book was released on 2020-03-05 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue Book entitled "Lamiaceae Species: Biology, Ecology and Practical Uses" contributes to the knowledge of selected Lamiaceae species from several perspectives, such as diversity and phytogeography, taxonomy, ethnobotany, and quantitative and qualitative composition, as well as the biological activity of secondary metabolites.

Environmental Aspects of the Transuranics

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Publisher :
ISBN 13 :
Total Pages : 212 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Environmental Aspects of the Transuranics by : F. M. Martin

Download or read book Environmental Aspects of the Transuranics written by F. M. Martin and published by . This book was released on 1975 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gharial Conservation in Nepal

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ISBN 13 :
Total Pages : 168 pages
Book Rating : 4.0/5 (889 download)

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Book Synopsis Gharial Conservation in Nepal by : Tirtha Man Maskey

Download or read book Gharial Conservation in Nepal written by Tirtha Man Maskey and published by . This book was released on 2008 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Desert Truffles

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Publisher : Springer Science & Business Media
ISBN 13 : 3642400965
Total Pages : 391 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Desert Truffles by : Varda Kagan-Zur

Download or read book Desert Truffles written by Varda Kagan-Zur and published by Springer Science & Business Media. This book was released on 2013-10-30 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Desert truffles are found in every known desert, irrespective of the habitat – cool or hot, loamy or acidic, sandy or heavy soil – the only common condition seems to be a limited supply of water. In contrast to ‘true’ truffles, desert truffles have evolved over time in different families, mainly within the order Pezizales. While in some arid areas, desert truffles have been traditionally used as food, in most regions interest has only recently been increasing, and truffles are now treasured for their nutritional value, as an income source and for research. This volume gives a comprehensive overview of the phylogeny, biology, mycorrhizal association, and distribution of desert truffles, their use, biochemical and medicinal properties, as well as their domestication and cultivation.

Advances in Plant Ecophysiology Techniques

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Publisher : Springer
ISBN 13 : 3319932330
Total Pages : 491 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Advances in Plant Ecophysiology Techniques by : Adela M. Sánchez-Moreiras

Download or read book Advances in Plant Ecophysiology Techniques written by Adela M. Sánchez-Moreiras and published by Springer. This book was released on 2018-08-17 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook covers the most commonly used techniques for measuring plant response to biotic and abiotic stressing factors, including: in vitro and in vivo bioassays; the study of root morphology, photosynthesis (pigment content, net photosynthesis, respiration, fluorescence and thermoluminiscence) and water status; thermal imaging; the measurement of oxidative stress markers; flow cytometry for measuring cell cycle and other physiological parameters; the use of microscope techniques for studying plant microtubules; programmed-cell-death; last-generation techniques (metabolomics, proteomics, SAR/QSAR); hybridization methods; isotope techniques for plant and soil studies; and the measurement of detoxification pathways, volatiles, soil microorganisms, and computational biology.

Submerged Prehistory

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Publisher : Oxbow Books Limited
ISBN 13 : 9781842174180
Total Pages : 0 pages
Book Rating : 4.1/5 (741 download)

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Book Synopsis Submerged Prehistory by : Jonathan Benjamin

Download or read book Submerged Prehistory written by Jonathan Benjamin and published by Oxbow Books Limited. This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Major events of human prehistory such as the post-glacial recolonization of Northern Europe and the spread of agriculture through the Mediterranean took place on landscapes that are now, at least partially, underwater. Large parts of this submerged terrain are accessible to divers and can be investigated archaeologically. Prehistoric underwater research has emerged in recent decades as a distinct sub-discipline, developing approaches and methodologies that can be applied in coastal regions worldwide. As a result there is growing awareness of the potential for underwater archaeology to transform our ideas about the course of prehistory. This volume examines existing practice and new developments in the field of submerged prehistoric landscape research. The 25 peer-reviewed contributions from leading authors cover the results of recent research on three continents and the application of methodologies and techniques for site discovery, investigation and interpretation.

Bio-Based Building Materials

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Publisher : Trans Tech Publications Ltd
ISBN 13 : 3035736995
Total Pages : 902 pages
Book Rating : 4.0/5 (357 download)

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Book Synopsis Bio-Based Building Materials by : Sofiane Amziane

Download or read book Bio-Based Building Materials written by Sofiane Amziane and published by Trans Tech Publications Ltd. This book was released on 2022-01-06 with total page 902 pages. Available in PDF, EPUB and Kindle. Book excerpt: Selected peer-reviewed full text papers from the 4th International Conference on Bio-Based Building Materials (ICBBM 2021) Selected peer-reviewed full text papers from the 4th International Conference on Bio-Based Building Materials (ICBBM 2021), June 16-18, 2021, Barcelona, Spain