Current Trends in X-Ray Crystallography

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Publisher : IntechOpen
ISBN 13 : 9789533077543
Total Pages : 450 pages
Book Rating : 4.0/5 (775 download)

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Book Synopsis Current Trends in X-Ray Crystallography by : Annamalai Chandrasekaran

Download or read book Current Trends in X-Ray Crystallography written by Annamalai Chandrasekaran and published by IntechOpen. This book was released on 2011-12-16 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book on X-ray Crystallography is a compilation of current trends in the use of X-ray crystallography and related structural determination methods in various fields. The methods covered here include single crystal small-molecule X-ray crystallography, macromolecular (protein) single crystal X-ray crystallography, and scattering and spectroscopic complimentary methods. The fields range from simple organic compounds, metal complexes to proteins, and also cover the meta-analyses of the database for weak interactions.

Current Trends in X-Ray Crystallography

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Publisher : BoD – Books on Demand
ISBN 13 : 9533077549
Total Pages : 452 pages
Book Rating : 4.5/5 (33 download)

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Book Synopsis Current Trends in X-Ray Crystallography by : Annamalai Chandrasekaran

Download or read book Current Trends in X-Ray Crystallography written by Annamalai Chandrasekaran and published by BoD – Books on Demand. This book was released on 2011-12-16 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book on X-ray Crystallography is a compilation of current trends in the use of X-ray crystallography and related structural determination methods in various fields. The methods covered here include single crystal small-molecule X-ray crystallography, macromolecular (protein) single crystal X-ray crystallography, and scattering and spectroscopic complimentary methods. The fields range from simple organic compounds, metal complexes to proteins, and also cover the meta-analyses of the database for weak interactions.

Handbook of X-Ray Crystallography

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Author :
Publisher :
ISBN 13 : 9781632382849
Total Pages : 0 pages
Book Rating : 4.3/5 (828 download)

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Book Synopsis Handbook of X-Ray Crystallography by : Sharon Levine

Download or read book Handbook of X-Ray Crystallography written by Sharon Levine and published by . This book was released on 2015-03-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: X-ray Crystallography is a scientific technique used to demonstrate the arrangement of atoms of a crystalline solid in 3D space. This book is a collection of latest trends, using X-ray crystallography and related structural determination techniques in a diverse variety of spheres. The procedures emphasized in this book consist of various processes and spectroscopic complimentary methods. The spectrum ranges from basic organic compounds to metal complexes to proteins and includes meta-analyses of a host of weak connections.

Small Angle Scattering and Diffraction

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Publisher : BoD – Books on Demand
ISBN 13 : 1789232465
Total Pages : 118 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Small Angle Scattering and Diffraction by : Margareth Kazuyo Kobayashi Dias Franco

Download or read book Small Angle Scattering and Diffraction written by Margareth Kazuyo Kobayashi Dias Franco and published by BoD – Books on Demand. This book was released on 2018-06-06 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reasoned and based on the difference between discovery and invention, according to the traditional conception, science can be distinguished between basic science and applied science. Nevertheless, we know that the sciences are inseparable. A century or more ago, Louis Pasteur said "there is no applied science, there are applications of science." With this assertion, he establishes the logic of complementarity between them. Science certainly goes beyond its own material application and brings us to issues that have intrigued humanity for a long time. During the many years that we have been working with techniques of material characterization, we observed that this complementarity was not always understood by the researchers. In line with the reasoning that the technique joined with science generates technology, the application of techniques that use x-ray and neutron sources seems to us of fundamental importance for the development of technology. In this way, we present in this book how the existing technology of material characterization can contribute to science and applied technology. The authors who contributed with this book sought to show the importance of applying the existing techniques in the development of their works.

Recent Advances in X-ray Characterization of Materials

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Publisher : Pergamon
ISBN 13 :
Total Pages : 288 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Recent Advances in X-ray Characterization of Materials by : Padmanabhan Krishna

Download or read book Recent Advances in X-ray Characterization of Materials written by Padmanabhan Krishna and published by Pergamon. This book was released on 1989 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Protein Molecular and Structural Biology Methods

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Publisher : Academic Press
ISBN 13 : 0323902650
Total Pages : 716 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Advances in Protein Molecular and Structural Biology Methods by : Timir Tripathi

Download or read book Advances in Protein Molecular and Structural Biology Methods written by Timir Tripathi and published by Academic Press. This book was released on 2022-01-14 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Protein Molecular and Structural Biology Methods offers a complete overview of the latest tools and methods applicable to the study of proteins at the molecular and structural level. The book begins with sections exploring tools to optimize recombinant protein expression and biophysical techniques such as fluorescence spectroscopy, NMR, mass spectrometry, cryo-electron microscopy, and X-ray crystallography. It then moves towards computational approaches, considering structural bioinformatics, molecular dynamics simulations, and deep machine learning technologies. The book also covers methods applied to intrinsically disordered proteins (IDPs)followed by chapters on protein interaction networks, protein function, and protein design and engineering. It provides researchers with an extensive toolkit of methods and techniques to draw from when conducting their own experimental work, taking them from foundational concepts to practical application. Presents a thorough overview of the latest and emerging methods and technologies for protein study Explores biophysical techniques, including nuclear magnetic resonance, X-ray crystallography, and cryo-electron microscopy Includes computational and machine learning methods Features a section dedicated to tools and techniques specific to studying intrinsically disordered proteins

Crystallization of Membrane Proteins

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Publisher : CRC Press
ISBN 13 : 1351088173
Total Pages : 376 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Crystallization of Membrane Proteins by : Hartmut Michel

Download or read book Crystallization of Membrane Proteins written by Hartmut Michel and published by CRC Press. This book was released on 2018-01-18 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: The precise knowledge of the structure of biological macromolecules forms the basis of understanding their function and their mechanism of action. It also lays the foundation for rational protein and drug design. The only method to obtain this knowledge is still crystallography. At present, the structures of about 400 proteins are known at or nearly at atomic proteins. However, only two of them are membrane proteins or complexes of the membrane proteins. The reasons for the difference is not the crystals of membrane proteins resists forming special problems when being analysed. The reason is that the membrane proteins resist into forming into well-ordered crystals. The intention of this book is to help to produce well-ordered crystals proteins and to provide guidelines, it is aimed at both biochemists and protein crystallographer‘s.

Chemical and Biochemical Approaches for the Study of Anesthetic Function

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Publisher : Academic Press
ISBN 13 : 0128127414
Total Pages : 432 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Chemical and Biochemical Approaches for the Study of Anesthetic Function by :

Download or read book Chemical and Biochemical Approaches for the Study of Anesthetic Function written by and published by Academic Press. This book was released on 2018-03-26 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical and Biochemical Approaches for the Study of Anesthetic Function, Part A, Volume 602 assembles new information on our understanding of anesthesia. This latest release in the series includes sections on how physical accuracy leads to biological relevance, best practices for simulating ligand-gated ion channels interacting with general anesthetics, computational approaches for studying voltage-gated ion channels modulation by general anesthetics, anesthetic parameterization, pharmacophore QSAR, QM, ONIOM, and kinetic modeling of electrophysiology data. We have selected the primary experts to write about each approach This provides one-stop shopping for all the means of addressing this complex question Anesthesia is enormously important as almost everybody receives it at some point

Advanced X-ray Crystallography

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Publisher : Springer Science & Business Media
ISBN 13 : 3642274072
Total Pages : 190 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Advanced X-ray Crystallography by : Kari Rissanen

Download or read book Advanced X-ray Crystallography written by Kari Rissanen and published by Springer Science & Business Media. This book was released on 2012-01-10 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Studies of Crystal Structure and Bonding, by Angelo Gavezzotti Cryo-Crystallography: Diffraction at Low Temperature and More, by Piero Macchi High-Pressure Crystallography, by Malcolm I. McMahon Chemical X-Ray Photodiffraction: Principles, Examples, and Perspectives, by Panče Naumov Powder Diffraction Crystallography of Molecular Solids, by Kenneth D. M. Harris

Introduction to Biomolecular Structure and Biophysics

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Publisher : Springer
ISBN 13 : 9811049688
Total Pages : 274 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Introduction to Biomolecular Structure and Biophysics by : Gauri Misra

Download or read book Introduction to Biomolecular Structure and Biophysics written by Gauri Misra and published by Springer. This book was released on 2017-09-07 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive book presents a modern concept in biophysics based on recently published research. It highlights various aspects of the biophysical fundamentals and techniques that are currently used to study different physical properties of biomolecules, and relates the biological phenomenon with the underlying physical concepts. The content is divided into nine chapters summarizing the structural details of proteins, including recently discovered novel folds, higher order structures of nucleic acids, as well as lipids and the physical forces governing the macromolecular interactions which are essential for the various biological processes. It also provides insights into the recent advances in biophysical techniques including Hydrogen Deuterium Exchange with Mass Spectrometry (HDX-MS), Small angle X-ray scattering (SAXS) and Cryo Electron Microscopy (cryo EM), supplemented with interesting experimental data. It is a valuable reference resource for anyone with a desire to gain a better understanding of the fundamentals of biophysical concepts and techniques of important biomolecules.

Characterization of Crystal Growth Defects by X-Ray Methods

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Publisher : Springer Science & Business Media
ISBN 13 : 1475711263
Total Pages : 615 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Characterization of Crystal Growth Defects by X-Ray Methods by : B.K. Tanner

Download or read book Characterization of Crystal Growth Defects by X-Ray Methods written by B.K. Tanner and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the proceedings of a NATO Advanced Study Institute entitled "Characterization of Crystal Growth Defects by X-ray Methods' held in the University of Durham, England from 29th August to 10th September 1979. The current interest in electronic materials, in particular silicon, gallium aluminium arsenide, and quartz, and the recent availability of synchrotron radiation for X-ray diffraction studies made this Advanced Study Institute particularly timely. Two main themes ran through the course: 1. A survey of the various types of defect occurring in crystal growth, the mechanism of their different methods of generation and their influence on the properties of relativelY perfect crystals. 2. A detailed and advanced course on the observation and characterization of such defects by X-ray methods. The main emphasis was on X-ray topographic techniques but a substantial amount of time was spent on goniometric techniques such as double crystal diffractometry and gamma ray diffraction. The presentation of material in this book reflects these twin themes. Section A is concerned with defects, Section C with techniques and in linking them. Section B provides a concise account of the basic theory necessary for the interpretation of X-ray topographs and diffractometric data. Although the sequence follows roughly the order of presentation at the Advanced Study Institute certain major changes have been made in order to improve the pedagogy. In particular, the first two chapters provide a vital, and seldom articulated, case for the need for characterization for crystals used in device technologies.

Solid State Development and Processing of Pharmaceutical Molecules

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Publisher : John Wiley & Sons
ISBN 13 : 352734635X
Total Pages : 578 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Solid State Development and Processing of Pharmaceutical Molecules by : Michael Gruss

Download or read book Solid State Development and Processing of Pharmaceutical Molecules written by Michael Gruss and published by John Wiley & Sons. This book was released on 2021-11-15 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solid State Development and Processing of Pharmaceutical Molecules A guide to the lastest industry principles for optimizing the production of solid state active pharmaceutical ingredients Solid State Development and Processing of Pharmaceutical Molecules is an authoritative guide that covers the entire pharmaceutical value chain. The authors—noted experts on the topic—examine the importance of the solid state form of chemical and biological drugs and review the development, production, quality control, formulation, and stability of medicines. The book explores the most recent trends in the digitization and automation of the pharmaceutical production processes that reflect the need for consistent high quality. It also includes information on relevant regulatory and intellectual property considerations. This resource is aimed at professionals in the pharmaceutical industry and offers an in-depth examination of the commercially relevant issues facing developers, producers and distributors of drug substances. This important book: Provides a guide for the effective development of solid drug forms Compares different characterization methods for solid state APIs Offers a resource for understanding efficient production methods for solid state forms of chemical and biological drugs Includes information on automation, process control, and machine learning as an integral part of the development and production workflows Covers in detail the regulatory and quality control aspects of drug development Written for medicinal chemists, pharmaceutical industry professionals, pharma engineers, solid state chemists, chemical engineers, Solid State Development and Processing of Pharmaceutical Molecules reviews information on the solid state of active pharmaceutical ingredients for their efficient development and production.

Advances in Nanostructured Composites

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Publisher : CRC Press
ISBN 13 : 1351644688
Total Pages : 642 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Advances in Nanostructured Composites by : Mahmood Aliofkhazraei

Download or read book Advances in Nanostructured Composites written by Mahmood Aliofkhazraei and published by CRC Press. This book was released on 2019-04-30 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt: Composites and nanocomposites are used in cases where long durability and strength of components are required; i.e., where high stress levels, erosion processes and multiphase environments are present, including the parts under collision and impact, the parts under rotating motion and erosion (like excavation drills in oil and gas wells). The first volume of this book aims to provide a guide for fabrication of new nanocomposites mainly based on carbon nanotubes and graphene. The main topics of this volume are: Application of Nano-powders for Formation of Metal Matrix of Composites, Conjugated Polymer Nanocomposites, Biopolymer Nanocomposites, Dental Nanocomposites, Graphene-based Nanocomposites for Electrochemical Energy Storage, Polymer/Filler Composites for Optical Diffuse Reflectors, Synthesis and Applications of LDH-Based Nanocomposites, Rubber—CNT Nanocomposites, Nanocomposite Fibers with Carbon Nanotubes, Fabrications of Graphene Based Nanocomposites for Electrochemical Sensing of Drug Molecules, Recent Advances in Graphene Metal Oxide Based Nanocomposites.

Photosynthesis. Energy from the Sun

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Publisher : Springer Science & Business Media
ISBN 13 : 1402067097
Total Pages : 1562 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Photosynthesis. Energy from the Sun by : John F. Allen

Download or read book Photosynthesis. Energy from the Sun written by John F. Allen and published by Springer Science & Business Media. This book was released on 2008-09-20 with total page 1562 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Proceedings of the 14th International Congress on Photosynthesis is a record of the most recent advances and emerging themes in the discipline. This volume contains over 350 contributions from some 800 participants attending the meeting in Glasgow, UK in July 2007. These range from summary overview presentations from plenary speakers to expanded content of posters presented by students and their supervisors featuring the most recent achievements in photosynthesis research. In the words of Professor Eva-Mari Aro, President of the international Society of Photosynthesis Research 2004-7, “Having been taken for granted for centuries, research in photosynthesis has now become a matter of utmost importance for the future of planet Earth...Major initiatives are underway that will use research into natural and artificial photosynthesis for sustainable energy production....”. These volumes thus provide a glimpse of the future, from the molecule to the biosphere

Structural Bioinformatics

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Publisher : John Wiley & Sons
ISBN 13 : 1118210565
Total Pages : 1105 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Structural Bioinformatics by : Jenny Gu

Download or read book Structural Bioinformatics written by Jenny Gu and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 1105 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structural Bioinformatics was the first major effort to show the application of the principles and basic knowledge of the larger field of bioinformatics to questions focusing on macromolecular structure, such as the prediction of protein structure and how proteins carry out cellular functions, and how the application of bioinformatics to these life science issues can improve healthcare by accelerating drug discovery and development. Designed primarily as a reference, the first edition nevertheless saw widespread use as a textbook in graduate and undergraduate university courses dealing with the theories and associated algorithms, resources, and tools used in the analysis, prediction, and theoretical underpinnings of DNA, RNA, and proteins. This new edition contains not only thorough updates of the advances in structural bioinformatics since publication of the first edition, but also features eleven new chapters dealing with frontier areas of high scientific impact, including: sampling and search techniques; use of mass spectrometry; genome functional annotation; and much more. Offering detailed coverage for practitioners while remaining accessible to the novice, Structural Bioinformatics, Second Edition is a valuable resource and an excellent textbook for a range of readers in the bioinformatics and advanced biology fields. Praise for the previous edition: "This book is a gold mine of fundamental and practical information in an area not previously well represented in book form." —Biochemistry and Molecular Education "... destined to become a classic reference work for workers at all levels in structural bioinformatics...recommended with great enthusiasm for educators, researchers, and graduate students." —BAMBED "...a useful and timely summary of a rapidly expanding field." —Nature Structural Biology "...a terrific job in this timely creation of a compilation of articles that appropriately addresses this issue." —Briefings in Bioinformatics

Fragment-Based Drug Discovery and X-Ray Crystallography

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Publisher : Springer Science & Business Media
ISBN 13 : 3642275397
Total Pages : 235 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Fragment-Based Drug Discovery and X-Ray Crystallography by : Thomas G. Davies

Download or read book Fragment-Based Drug Discovery and X-Ray Crystallography written by Thomas G. Davies and published by Springer Science & Business Media. This book was released on 2012-01-23 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Fragment-Based Drug Discovery, by Daniel A. Erlanson Fragment Screening Using X-Ray Crystallography, by Thomas G. Davies and Ian J. Tickle Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening, by Stephen Roughley, Lisa Wright, Paul Brough, Andrew Massey and Roderick E. Hubbard Combining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 Inhibitors, by Daniel F. Wyss, Yu-Sen Wang, Hugh L. Eaton, Corey Strickland, Johannes H. Voigt, Zhaoning Zhu and Andrew W. Stamford Combining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery, by Michael Hennig, Armin Ruf and Walter Huber Targeting Protein–Protein Interactions and Fragment-Based Drug Discovery, by Eugene Valkov, Tim Sharpe, May Marsh, Sandra Greive and Marko Hyvönen Fragment Screening and HIV Therapeutics, by Joseph D. Bauman, Disha Patel and Eddy Arnold Fragment-Based Approaches and Computer-Aided Drug Discovery, by Didier Rognan

Biochemistry (Loose-Leaf)

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Publisher : Macmillan
ISBN 13 : 9781429235020
Total Pages : 1164 pages
Book Rating : 4.2/5 (35 download)

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Book Synopsis Biochemistry (Loose-Leaf) by : Jeremy M. Berg

Download or read book Biochemistry (Loose-Leaf) written by Jeremy M. Berg and published by Macmillan. This book was released on 2007 with total page 1164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Useful for students, this work deals with Biochemistry, introducing developments.