Current Research In Systemic Lupus Erythematosus

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Current Research in Systemic Lupus Erythematosus

Author : Carrie Kane
Publisher :
ISBN 13 : 9781632429162
Total Pages : 237 pages
Book Rating : 4.4/5 (291 download)

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Book Synopsis Current Research in Systemic Lupus Erythematosus by : Carrie Kane

Download or read book Current Research in Systemic Lupus Erythematosus written by Carrie Kane and published by . This book was released on 2020-09-22 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systemic lupus erythematosus is an autoimmune disease characterized by fever, painful and swollen joints, chest pain, swollen lymph nodes, red rash, etc. This condition is caused because the immune system of the body attacks many healthy tissues of the body. It is believed to arise due to a combination of genetic and environmental factors. Some of the risk factors associated with the incidence of this disease are vitamin D deficiency, female sex hormones, smoking, certain infections and sunlight. It can be diagnosed through serologic testing. Clinically indirect immunofluorescence is the most widely used method. Testing for complement system levels, liver enzymes, electrolytes and kidney function, and complete blood count also aid in the diagnosis. The treatment of systemic lupus erythematosus involves the use of corticosteroids and anti-malarial drugs. Some forms of lupus nephritis may require intermittent cytotoxic drugs. This book brings forth some of the most innovative concepts and elucidates the unexplored aspects of systemic lupus erythematosus. It presents researches and studies performed by experts across the globe. Through this book, we attempt to enlighten the readers about the new concepts in the diagnosis and treatment of systemic lupus erythematosus.

Lupus

Author : Sophia Lionaki
Publisher : BoD – Books on Demand
ISBN 13 : 1838801693
Total Pages : 140 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Lupus by : Sophia Lionaki

Download or read book Lupus written by Sophia Lionaki and published by BoD – Books on Demand. This book was released on 2020-03-25 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systemic lupus erythematosus, the prototype of an autoimmune disorder, may affect several organs and may run a chronic course between relapse and remission. This book covers important aspects of the disease, including epidemiology, pathophysiology, and neuropsychiatric manifestations, including basic science and clinical features and management. In affected patients, the fundamental problem of fertility is reassessed including the risk of the disease, the possibility of fetal loss, the safety of drugs during pregnancy, and the current diagnostic and suggested therapeutic strategies of reproductive medicine. Finally, the issue of pathogenesis is revisited with a thorough description of animal models in relation to physiology and potential novel therapies.

Systemic Lupus Erythematosus: New Insights for the Healthcare Professional: 2011 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464902003
Total Pages : 200 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Systemic Lupus Erythematosus: New Insights for the Healthcare Professional: 2011 Edition by :

Download or read book Systemic Lupus Erythematosus: New Insights for the Healthcare Professional: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systemic Lupus Erythematosus: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Systemic Lupus Erythematosus. The editors have built Systemic Lupus Erythematosus: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Systemic Lupus Erythematosus in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Systemic Lupus Erythematosus: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Current Rheumatology Diagnosis & Treatment

Author : John B. Imboden
Publisher : McGraw-Hill/Appleton & Lange
ISBN 13 :
Total Pages : 532 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Current Rheumatology Diagnosis & Treatment by : John B. Imboden

Download or read book Current Rheumatology Diagnosis & Treatment written by John B. Imboden and published by McGraw-Hill/Appleton & Lange. This book was released on 2004 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: An ideal quick reference for primary care providers, specialists, and trainees, this accessible resource offers up-to-date assessment and management solutions for the entire range of rheumatologic diseases.

Systemic Lupus Erythematosus: Advances in Research and Treatment: 2011 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464945551
Total Pages : 35 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Systemic Lupus Erythematosus: Advances in Research and Treatment: 2011 Edition by :

Download or read book Systemic Lupus Erythematosus: Advances in Research and Treatment: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 35 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systemic Lupus Erythematosus: Advances in Research and Treatment: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Systemic Lupus Erythematosus in a compact format. The editors have built Systemic Lupus Erythematosus: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Systemic Lupus Erythematosus in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Systemic Lupus Erythematosus: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Pathogenesis of Systemic Lupus Erythematosus

Author : Alberta Hoi
Publisher : Springer Nature
ISBN 13 : 3030851613
Total Pages : 192 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Pathogenesis of Systemic Lupus Erythematosus by : Alberta Hoi

Download or read book Pathogenesis of Systemic Lupus Erythematosus written by Alberta Hoi and published by Springer Nature. This book was released on 2021-11-15 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scope of this contributed volume is to provide an overview of the latest translational research in the field of lupus pathogenesis, with particular emphasis on how these discoveries progress in parallel with therapeutic drug development. Systemic lupus erythematosus (SLE) is a multifaceted disease with a number of well-defined immune pathways that are dysregulated, resulting in an immune-mediated chronic inflammatory injury at target organs. As knowledge of these pathways evolves to provide opportunities for targeted drug therapy and lays the foundation for personalized medicine, clinicians and researchers need to keep up with the ever-expanding medical literature. This book will critically appraise the current understanding of important immunological pathways that contribute to the pathogenesis of lupus. We will review the role of interferons as part of the innate immune defects that perpetuate the loss of self-tolerance in SLE. B cell hyperactivity, as a defining hallmark of SLE, and different strategies of B cell targeted therapy will be discussed. The role of co-stimulation or immune checkpoint molecules in activating B and T cells will be reviewed, as well as other cytokines that serve in the amplification loop promoting a more proinflammatory Th1 or Th17 responses. Intracellular targets, such as signaling molecules in the JAK/STAT pathway, or a variety of kinases and proteasomes, can cause a cascading downstream effect of transcriptional responses that are important in SLE. Immune homeostasis can also be restored by bolstering the naturally occurring anti-inflammatory mechanisms. Glucocorticoid, as a potent natural anti-inflammatory hormone, can mediate its effects by recruiting histone deacetylase that serve to repress gene transcription. Glucocorticoid-induced leucine zipper is a gene upregulated by glucocorticoid that can be a potential target for development of anti-inflammatory strategy. Finally, T regulatory cells can be utilized to help restore to immune tolerance and are amongst the latest focus of therapeutic development in SLE.

Systemic Lupus Erythematosus: New Insights for the Healthcare Professional: 2013 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481662341
Total Pages : 180 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Systemic Lupus Erythematosus: New Insights for the Healthcare Professional: 2013 Edition by :

Download or read book Systemic Lupus Erythematosus: New Insights for the Healthcare Professional: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-07-22 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systemic Lupus Erythematosus: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Systemic Lupus Erythematosus: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Systemic Lupus Erythematosus: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Lahita's Systemic Lupus Erythematosus

Author : Robert G. Lahita
Publisher : Elsevier
ISBN 13 : 0128205830
Total Pages : 730 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Lahita's Systemic Lupus Erythematosus by : Robert G. Lahita

Download or read book Lahita's Systemic Lupus Erythematosus written by Robert G. Lahita and published by Elsevier. This book was released on 2021-07-27 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systemic lupus erythematosus (SLE), commonly called lupus, is a chronic autoimmune disorder that can affect virtually any organ of the body. In lupus, the body's immune system, which normally functions to protect against foreign invaders, becomes hyperactive, forming antibodies that attack normal tissues and organs, including the skin, joints, kidneys, brain, heart, lungs, and blood. Lupus is characterized by periods of illness, called flares, and periods of wellness or remission. Because its symptoms come and go and mimic those of other diseases, lupus is difficult to diagnose. There is no single laboratory test that can definitively prove that a person has the complex illness. To date, lupus has no known cause or cure. Early detection and treatment are the key to a better health outcome and can usually lessen the progression and severity of the disease. Anti-inflammatory drugs, antimalarials, and steroids (such as cortisone and others) are often used to treat lupus. Cytotoxic chemotherapies, like those used in the treatment of cancer, are also used to suppress the immune system in lupus patients. A new edition of this established and well-regarded reference combines basic science with clinical science to provide a translational medicine model. Systemic Lupus Erythematosus, Sixth Edition, is a useful reference for specialists in the diagnosis and management of patients with SLE, a tool for measurement of clinical activity for pharmaceutical development and basic research of the disease, and a reference work for hospital libraries. Completely updated, revised, and expanded with the most comprehensive and accessible reference on SLE for clinicians and scientists Full-color presentation throughout the book Provides the latest information available on diagnosis and treatment Incorporates an international panel of authors who are experts in their fields, with an emphasis on young, cutting-edge scientists and physicians

Recent Advances in Systemic Lupus Erythematosus

Author : Paul Henri Lambert
Publisher :
ISBN 13 :
Total Pages : 359 pages
Book Rating : 4.:/5 (251 download)

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Book Synopsis Recent Advances in Systemic Lupus Erythematosus by : Paul Henri Lambert

Download or read book Recent Advances in Systemic Lupus Erythematosus written by Paul Henri Lambert and published by . This book was released on 1984 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Systemic Lupus Erythematosus: New Insights for the Healthcare Professional: 2012 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464971625
Total Pages : 142 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Systemic Lupus Erythematosus: New Insights for the Healthcare Professional: 2012 Edition by :

Download or read book Systemic Lupus Erythematosus: New Insights for the Healthcare Professional: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-10 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systemic Lupus Erythematosus: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Systemic Lupus Erythematosus. The editors have built Systemic Lupus Erythematosus: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Systemic Lupus Erythematosus in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Systemic Lupus Erythematosus: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Progress in Systemic Lupus Erythematosus Research

Author : Tomas I. Seward
Publisher : Nova Publishers
ISBN 13 : 9781600218613
Total Pages : 284 pages
Book Rating : 4.2/5 (186 download)

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Book Synopsis Progress in Systemic Lupus Erythematosus Research by : Tomas I. Seward

Download or read book Progress in Systemic Lupus Erythematosus Research written by Tomas I. Seward and published by Nova Publishers. This book was released on 2007 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new book is devoted to leading-edge research developments in lupus which is a condition of chronic inflammation caused by an autoimmune disease. Autoimmune diseases are illnesses that occur when the body's tissues are attacked by its own immune system. The immune system is a complex system within the body that is designed to fight infectious agents, for example, bacteria, and other foreign invaders. One of the mechanisms that the immune system uses to fight infections is the production of antibodies. Patients with lupus produce abnormal antibodies in their blood that target tissues within their own body rather than foreign infectious agents. Because the antibodies and accompanying cells of inflammation can involve tissues anywhere in the body, lupus has the potential to affect a variety of areas of the body. Sometimes lupus can cause disease of the skin, heart, lungs, kidneys, joints, and/or nervous system. When only the skin is involved, the condition is called discoid lupus. When internal organs are involved, the condition is called systemic lupus erythematosus (SLE).

New Directions for Research in Systemic Lupus Erythematosus

Author : Arthritis Foundation
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (846 download)

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Book Synopsis New Directions for Research in Systemic Lupus Erythematosus by : Arthritis Foundation

Download or read book New Directions for Research in Systemic Lupus Erythematosus written by Arthritis Foundation and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Outcome Measures and Metrics in Systemic Lupus Erythematosus

Author : Zahi Touma
Publisher : Springer Nature
ISBN 13 : 3030733033
Total Pages : 418 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Outcome Measures and Metrics in Systemic Lupus Erythematosus by : Zahi Touma

Download or read book Outcome Measures and Metrics in Systemic Lupus Erythematosus written by Zahi Touma and published by Springer Nature. This book was released on 2021-07-22 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that manifests with a myriad of clinical and laboratory features. The assessment of SLE is comprehensive and includes different core set domains; disease activity, damage, health-related quality of life, adverse events and economic impact. This comprehensive book is focused on the instruments and outcome measures utilized in the assessment of SLE. It targets different audiences including physicians, scientists/researchers and different health professionals interested in learning about the art of measurement in SLE. The book highlights the importance of measurement in the assessment of SLE in a clinical settings, research and clinical trials. Each of the chapters provide a systematic approach to the instruments utilized in the assessment of a specific construct in SLE (e.g., disease activity, fatigue, etc.) and incorporate a comprehensive coverage of disease specific and disease generic measures. It also discusses different patient-reported outcomes that are crucial to reflect patient perceptions of their health condition and cover constructs such as fatigue, pain, anxiety and depression, cognition, frailty, and many others.

Lupus: New Insights for the Healthcare Professional: 2011 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464901945
Total Pages : 189 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Lupus: New Insights for the Healthcare Professional: 2011 Edition by :

Download or read book Lupus: New Insights for the Healthcare Professional: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lupus: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Lupus. The editors have built Lupus: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Lupus in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Lupus: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Systemic Lupus Erythematosus

Author :
Publisher :
ISBN 13 :
Total Pages : 40 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Systemic Lupus Erythematosus by :

Download or read book Systemic Lupus Erythematosus written by and published by . This book was released on 2000 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Systemic Lupus Erythematosus

Author : Caroline Gordon
Publisher : Oxford University Press
ISBN 13 : 0198739184
Total Pages : 161 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis Systemic Lupus Erythematosus by : Caroline Gordon

Download or read book Systemic Lupus Erythematosus written by Caroline Gordon and published by Oxford University Press. This book was released on 2016 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systemic Lupus Erythematosus provides a practical approach to the assessment and management of patients with this complex, multisystem autoimmune disease to improve the diagnosis and treatment of the disease and its complications.

Systemic Lupus Erythematosus E-Book

Author : George Tsokos
Publisher : Elsevier Health Sciences
ISBN 13 : 0323070876
Total Pages : 607 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Systemic Lupus Erythematosus E-Book by : George Tsokos

Download or read book Systemic Lupus Erythematosus E-Book written by George Tsokos and published by Elsevier Health Sciences. This book was released on 2007-02-23 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new companion to Hochberg et al.'s Rheumatology masterwork provides new insights into the causes, detection and therapy of this challenging disease. In this state-of-the-art resource, you'll find ‘one stop' coverage of all the latest scientific and clinical developments in SLE: new concepts in epidemiology, disease activity measures and outcomes; new concepts in immunoregulation, genetic and pathogenic mechanisms; new understanding and novel presentation of the processes of tissue/organ damage; comprehensive coverage of clinical features; and the very latest concepts in treatment. Provides the very latest understanding of the pathogenesis of SLE. Distills current understanding of the cellular, molecular, genetic and environmental factors that instigate and drive the disease. Includes comprehensive coverage of clinical features, including fatigue, organ system manifestations, overlap syndromes, infections, and more. Conveys the very latest understanding of mechanisms of tissue damage, including immune complexes, antibodies, and other mechanisms that lead to organ damage. Contains expert discussion of processes that are responsible for tissue injury - a hallmark of this text. Incorporates the latest treatment modalities, including steroids and non-steroidals, cytotoxic drug treatment, PAP's, and therapies on the horizon. Discusses the latest treatment options on disease modifying or disease controlling agents.