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Author : CPNC
Publisher :
ISBN 13 : 9780555008713
Total Pages : pages
Book Rating : 4.0/5 (87 download)
Download or read book Current Protocols in Nucleic Acid Chemistry Binder written by CPNC and published by . This book was released on 2003-03-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Beaucage
Publisher :
ISBN 13 : 9780555002117
Total Pages : pages
Book Rating : 4.0/5 (21 download)
Download or read book Current Protocols in Nucleic Acid Chemistry Binder written by Beaucage and published by . This book was released on 2002-10-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Serge L. Beaucage
Publisher : Current Protocols
ISBN 13 : 9780471246626
Total Pages : pages
Book Rating : 4.2/5 (466 download)
Download or read book Current Protocols in Nucleic Acid Chemistry written by Serge L. Beaucage and published by Current Protocols. This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Good methods must be reliable, well-tested, and honed to minimize the time and expense required to achieve the desired results. CPNC provides a continuously growing and evolving set of protocols that allows researchers to benefit from the experience of other researchers around the world. The core manual provides a comprehensive set of protocols that have been compiled, revised, and streamlined over the last 6 years. Quarterly updates provide new protocols in emerging areas of research as well as continued advances and new applications for fundamental methods. The book is designed to grow and change with the field of nucleic acid chemistry. Fundamental nucleoside chemistry methods include sugar-base condensation, phosphorylation, and nucleoside protection. Methods for oligonucleotide synthesis include H-phosphonate and phosphoramidite approaches, solid-phase and solution-phase synthesis, large-scale synthesis, synthesis for modified and unmodified oligonucleotides, conjugation of oligonucleotides, synthesis without base protection, and synthesis on microarrays. More specialized synthetic methods include synthesis of biologically active nucleosides and prodrugs. Purification and characterization methods are detailed. Advanced methods include biophysical analysis, combinatorial methods, and nanotechnology. Each protocol includes rationale for choosing appropriate methods, step-by-step procedures, complete recipes, anticipated results, characterization data, and troubleshooting, as well as background and recommended reading. The level of procedural detail is far beyond that found in the research literature, and tips and comments from authors are geared towards ensuring reliable duplication in the laboratory.
Author : Serge L. Beaucage
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (838 download)
Download or read book Current Protocols in Nucleic Acid Chemistry written by Serge L. Beaucage and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Bergstrom
Publisher : Current Protocols
ISBN 13 : 9780471142706
Total Pages : pages
Book Rating : 4.1/5 (427 download)
Download or read book Current Protocols in Nucleic Acid Chemistry Online written by Bergstrom and published by Current Protocols. This book was released on 2003-04-16 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Beaucage
Publisher :
ISBN 13 : 9780555005736
Total Pages : pages
Book Rating : 4.0/5 (57 download)
Download or read book Current Protocols in Nucleic Acid Chemistry Supplement written by Beaucage and published by . This book was released on 2002-10-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Beaucage
Publisher :
ISBN 13 : 9780555009192
Total Pages : pages
Book Rating : 4.0/5 (91 download)
Download or read book Current Protocols in Nucleic Acid Chemistry Supplement 21 written by Beaucage and published by . This book was released on 2005-06-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : CPNC
Publisher :
ISBN 13 : 9780555008690
Total Pages : pages
Book Rating : 4.0/5 (86 download)
Download or read book Current Protocols in Nucleic Acid Chemistry Core Reprint written by CPNC and published by . This book was released on 2003-03-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Beaucage
Publisher :
ISBN 13 : 9780555002124
Total Pages : pages
Book Rating : 4.0/5 (21 download)
Download or read book Current Protocols in Nucleic Acid Chemistry Core Reprint written by Beaucage and published by . This book was released on 2002-10-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : CPNC
Publisher :
ISBN 13 : 9780555008706
Total Pages : pages
Book Rating : 4.0/5 (87 download)
Download or read book Current Protocols in Nucleic Acid Chemistry Tabs Reprint written by CPNC and published by . This book was released on 2003-03-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Beaucage
Publisher :
ISBN 13 : 9780555002209
Total Pages : pages
Book Rating : 4.0/5 (22 download)
Download or read book Current Protocols in Nucleic Acid Chemistry Tabs Reprint written by Beaucage and published by . This book was released on 2002-10-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Beaucage
Publisher : John Wiley & Sons
ISBN 13 : 9780471246602
Total Pages : pages
Book Rating : 4.2/5 (466 download)
Download or read book Current Protocols in Nucleic Acid Chemistry on CD-ROM written by Beaucage and published by John Wiley & Sons. This book was released on 1999-01-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Frederick M. Ausubel
Publisher :
ISBN 13 :
Total Pages : 1020 pages
Book Rating : 4.3/5 (91 download)
Download or read book Current Protocols in Molecular Biology written by Frederick M. Ausubel and published by . This book was released on 1987 with total page 1020 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Frederick M. Ausubel
Publisher :
ISBN 13 : 9780555001219
Total Pages : pages
Book Rating : 4.0/5 (12 download)
Download or read book Current Protocols in Molecular Biology Binder Volu Me written by Frederick M. Ausubel and published by . This book was released on 2002-04-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ralph Rapley
Publisher : Springer Science & Business Media
ISBN 13 : 1592590381
Total Pages : 997 pages
Book Rating : 4.5/5 (925 download)
Download or read book The Nucleic Acid Protocols Handbook written by Ralph Rapley and published by Springer Science & Business Media. This book was released on 2008-06-29 with total page 997 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive treasury of all the key molecular biology methods-ranging from DNA extraction to gene localization in situ-needed to function effectively in the modern laboratory. Each of the 120 highly successful techniques follows the format of the much acclaimed Methods in Molecular BiologyOao series, providing an introduction to the scientific basis of each technique, a complete listing of all the necessary materials and reagents, and clear step-by-step instruction to permit error-free execution. Included for each technique are notes about pitfalls to avoid, troubleshooting tips, alternate methods, and explanations of the reasons for certain steps-all key elements contributing significantly to success or failure in the lab. The Nucleic Acid Protocols Handbook constitutes today's most comprehensive collection of all the key classic and cutting-edge techniques for the successful isolation, analysis, and manipulation of nucleic acids by both experienced researchers and those new to the field."
Author : Frederick M. Ausubel
Publisher :
ISBN 13 : 9780555012406
Total Pages : pages
Book Rating : 4.0/5 (124 download)
Download or read book Current Protocols in Molecular Biology Core written by Frederick M. Ausubel and published by . This book was released on 2003-05-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Martine Demeunynck
Publisher : John Wiley & Sons
ISBN 13 : 3527605665
Total Pages : 754 pages
Book Rating : 4.5/5 (276 download)
Download or read book Small Molecule DNA and RNA Binders written by Martine Demeunynck and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of molecules that selectively bind to nucleic acids has provided many details about DNA and RNA recognition. The range of such substances, such as metal complexes, peptides, oligonucleotides and a wide array of synthetic organic compounds, is as manifold as the functions of nucleic acids. Nucleic acid recognition sequences are often found in the major or minor groove of a double strand, while other typical interactions include intercalation between base pairs or the formation of triple or quadruple helices. One example of a binding mode that has recently been proposed is end stacking on such complex structures as the telomere tetraplex. In this comprehensive book, internationally recognized experts describe in detail the important aspects of nucleic acid binding, and in so doing present impressive approaches to drug design. Since typical substances may be created naturally or synthetically, emphasis is placed on natural products, chemical synthesis, the use of combinatorial libraries, and structural characterization. The whole is rounded off by contributions on molecular modeling, as well as investigations into the way in which any given drug interacts with its nucleic acid recognition site.
