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Author : Nicholas C. Dracopoli
Publisher :
ISBN 13 : 9780555012383
Total Pages : pages
Book Rating : 4.0/5 (123 download)
Download or read book Current Protocols in Human Genetics Tabs written by Nicholas C. Dracopoli and published by . This book was released on 2003-04-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Nicholas C. Dracopoli
Publisher :
ISBN 13 : 9780555008089
Total Pages : pages
Book Rating : 4.0/5 (8 download)
Download or read book Current Protocols in Human Genetics Tabs Reprint written by Nicholas C. Dracopoli and published by . This book was released on 2002-10-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 : 9780471161325
Total Pages : pages
Book Rating : 4.1/5 (613 download)
Download or read book Current Protocols on CD-ROM. written by and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Sean R. Gallagher
Publisher : John Wiley & Sons
ISBN 13 : 047094241X
Total Pages : 679 pages
Book Rating : 4.4/5 (79 download)
Download or read book Current Protocols Essential Laboratory Techniques written by Sean R. Gallagher and published by John Wiley & Sons. This book was released on 2012-03-19 with total page 679 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest title from the acclaimed Current Protocols series, Current Protocols Essential Laboratory Techniques, 2e provides the new researcher with the skills and understanding of the fundamental laboratory procedures necessary to run successful experiments, solve problems, and become a productive member of the modern life science laboratory. From covering the basic skills such as measurement, preparation of reagents and use of basic instrumentation to the more advanced techniques such as blotting, chromatography and real-time PCR, this book will serve as a practical reference manual for any life science researcher. Written by a combination of distinguished investigators and outstanding faculty, Current Protocols Essential Laboratory Techniques, 2e is the cornerstone on which the beginning scientist can develop the skills for a successful research career.
Author : Indranil Mukhopadhyay
Publisher : Springer Nature
ISBN 13 : 9819932203
Total Pages : 281 pages
Book Rating : 4.8/5 (199 download)
Download or read book Statistical Methods in Human Genetics written by Indranil Mukhopadhyay and published by Springer Nature. This book was released on 2023-10-10 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of statistical concepts and basic methodology for the study of genetics of human traits and diseases. It attempts to provide a step-by-step description of problem identification, study design, methodology of data collection, data exploration, data summarization and visualization, and more advanced analytical methods for inferring genetic underpinnings of human phenotypes. The book provides codes in R programming language for implementation of most of the statistical methods described, which will enable practitioners to perform analysis of data on their own, without having to mold the data to fit the requirements of commercial statistical packages. Useful to anyone engaged in studies to understand and manage good health, the book is a useful guide for sustainable development of humankind. Primarily intended for practicing biologists especially those who carry out quantitative biological research, in particular, human geneticists, the book is also helpful in classroom teaching.
Author : Aad Tibben
Publisher : Academic Press
ISBN 13 : 9780128133354
Total Pages : 0 pages
Book Rating : 4.1/5 (333 download)
Download or read book Clinical Genome Sequencing written by Aad Tibben and published by Academic Press. This book was released on 2019-04-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Genome Sequencing: Psychological Aspects thoroughly details key psychological factors to consider while implementing genome sequencing in clinical practice, taking into account the subtleties of genetic risk assessment, patient consent and best practices for sharing genomic findings. Chapter contributions from leading international researchers and practitioners cover topics ranging from the current state of genomic testing, to patient consent, patient responses to sequencing data, common uncertainties, direct-to-consumer genomics, the role of genome sequencing in precision medicine, genetic counseling and genome sequencing, genome sequencing in pediatrics, genome sequencing in prenatal testing, and ethical issues in genome sequencing. Applied clinical case studies support concept illustration, making this an invaluable, practical reference for this important and multifaceted topic area within genomic medicine.
Author :
Publisher : Academic Press
ISBN 13 : 0128243260
Total Pages : 972 pages
Book Rating : 4.1/5 (282 download)
Download or read book Medical Epigenetics written by and published by Academic Press. This book was released on 2021-08-27 with total page 972 pages. Available in PDF, EPUB and Kindle. Book excerpt: **Selected for Doody's Core Titles® 2024 in Clinical Genetics** Medical Epigenetics, Second Edition provides a comprehensive analysis of epigenetics in health management, across a broad spectrum of disease categories and specialties, and with a focus on human systems, epigenetic diseases that affect these systems, and evolving modes of epigenetic-based treatment. Here, more than 40 leading researchers examine how each human system is affected by epigenetic maladies, offering an all-in-one resource on medical epigenetics not only for those directly involved with health care, but investigators in life sciences, biotech companies, graduate students, and others who are interested in applied aspects of epigenetics. Incorporating both diagnostic and prognostic epigenetic approaches, this volume also fully supports the application of epigenetics in precision medicine. This second edition of Medical Epigenetics, a volume in the Translational Epigenetics series, has been fully revised to address recent advances in disease epigenetics and role of epigenetics in precision medicine, with all-new chapters on skin cancer epigenetics, network analysis in medical epigenetics, machine learning in epigenetic diseases, and clinical trials of epigenetics drugs. - Features chapters from leading researchers and clinicians dedicated to the burgeoning role of epigenetics in medical practice - Covers emerging topics, including twin epigenetics, as well as epigenetics of gastrointestinal disease, muscle disorders, endocrine disorders, ocular medicine, pediatric diseases, sports medicine, noncoding RNA therapeutics, pain management and regenerative medicine - Organized from system disorders to multi-system disorders that involve epigenetic aberrations - Examines the role of epigenetics in precision medicine
Author : Michael P. Starkey
Publisher : Springer Science & Business Media
ISBN 13 : 159259235X
Total Pages : 537 pages
Book Rating : 4.5/5 (925 download)
Download or read book Genomics Protocols written by Michael P. Starkey and published by Springer Science & Business Media. This book was released on 2008-02-03 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: We must unashamedly admit that a large part of the motivation for editing Genomics Protocols was selfish. The possibility of assembling in a single volume a unique and comprehensive collection of complete protocols, relevant to our work and the work of our colleagues, was too good an opportunity to miss. We are pleased to report, however, that the outcome is something of use not only to those who are experienced practitioners in the genomics field, but is also valuable to the larger community of researchers who have recognized the potential of genomics research and may themselves be beginning to explore the technologies involved. Some of the techniques described in Genomics Protocols are clearly not restricted to the genomics field; indeed, a prerequisite for many procedures in this discipline is that they require an extremely high throughput, beyond the scope of the average investigator. However, what we have endeavored here to achieve is both to compile a collection of procedures concerned with geno- scale investigations and to incorporate the key components of “bottom-up” and “top-down” approaches to gene finding. The technologies described extend from those traditionally recognized as coming under the genomics umbrella, touch on proteomics (the study of the expressed protein complement of the genome), through to early therapeutic approaches utilizing the potential of genome programs via gene therapy (Chapters 27–30).
Author :
Publisher : Academic Press
ISBN 13 : 012816574X
Total Pages : 228 pages
Book Rating : 4.1/5 (281 download)
Download or read book Cellular and Animal Models in Human Genomics Research written by and published by Academic Press. This book was released on 2019-07-30 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular and Animal Models in Human Genomics Research provides an indispensable resource for applying comparative genomics in the annotation of disease-gene associated variants that are identified by human genomic sequencing. The book presents a thorough overview of effective protocols for the use of cellular and animal modeling methods to turn lists of plausible genes into causative biomarkers. With chapters written by international experts, the book first addresses the fundamental aspects of using cellular and animal models in genetic and genomic studies, including in-depth examples of specific models and their utility, i.e., yeast, worms, flies, fish, mice and large animals. Protocols for properly conducting model studies, genomic technology, modeling candidate genes vs. genetic variants, integrative modeling, utilizing induced pluripotent stem cells, and employing CRISPR-Cas9 are also discussed in-depth. - Provides a thorough, accessible resource that helps researchers and students employ cellular and animal models in their own genetic and genomic studies - Offers guidance on how to effectively interpret the results and significance of genetic and genomic model studies for human health - Features chapters from international experts in the use of specific cellular and animal models, including yeast, worms, flies, fish, mice, and large animals, among other organisms
Author : Christoph W. Sensen
Publisher : John Wiley & Sons
ISBN 13 : 3527612653
Total Pages : 442 pages
Book Rating : 4.5/5 (276 download)
Download or read book Essentials of Genomics and Bioinformatics written by Christoph W. Sensen and published by John Wiley & Sons. This book was released on 2008-09-26 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides an overview of the rapidly evolving field of genomics with coverage of nucleic acid technologies, proteomics and bioinformatics. It includes chapters on applications in human health, agriculture and comparative genomics and also contains two chapters on the legal and ethical issues of genomics, a topic that is becoming increasingly important as genomics moves out of the laboratory into practical applications.
Author : Vinood B. Patel
Publisher : Springer Nature
ISBN 13 : 3031080149
Total Pages : 1163 pages
Book Rating : 4.0/5 (31 download)
Download or read book Biomarkers in Diabetes written by Vinood B. Patel and published by Springer Nature. This book was released on 2022-09-29 with total page 1163 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook focuses specifically on biomarkers in diabetes and provides a comprehensive understanding of this field. Readers will gain deep insights into bioinformatics and network analysis of biomarkers in diabetes, and will learn about circulating biomarkers in body fluids and specific pathological features of diabetes. Various animal models in diabetes research are also presented. In addition, like the previous volumes in this large reference series, the book provides a comprehensive look at genetics, cellular, and histological variables. The goal of this handbook is to provide information on markers of this disease to facilitate diagnosis, introduce new technologies, and ultimately improve health. It is a must for researchers as well as advanced students and physicians in the field of diabetes and biomarker research and application.
Author : Ion Mandoiu
Publisher : John Wiley & Sons
ISBN 13 : 1118169484
Total Pages : 460 pages
Book Rating : 4.1/5 (181 download)
Download or read book Computational Methods for Next Generation Sequencing Data Analysis written by Ion Mandoiu and published by John Wiley & Sons. This book was released on 2016-10-03 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces readers to core algorithmic techniques for next-generation sequencing (NGS) data analysis and discusses a wide range of computational techniques and applications This book provides an in-depth survey of some of the recent developments in NGS and discusses mathematical and computational challenges in various application areas of NGS technologies. The 18 chapters featured in this book have been authored by bioinformatics experts and represent the latest work in leading labs actively contributing to the fast-growing field of NGS. The book is divided into four parts: Part I focuses on computing and experimental infrastructure for NGS analysis, including chapters on cloud computing, modular pipelines for metabolic pathway reconstruction, pooling strategies for massive viral sequencing, and high-fidelity sequencing protocols. Part II concentrates on analysis of DNA sequencing data, covering the classic scaffolding problem, detection of genomic variants, including insertions and deletions, and analysis of DNA methylation sequencing data. Part III is devoted to analysis of RNA-seq data. This part discusses algorithms and compares software tools for transcriptome assembly along with methods for detection of alternative splicing and tools for transcriptome quantification and differential expression analysis. Part IV explores computational tools for NGS applications in microbiomics, including a discussion on error correction of NGS reads from viral populations, methods for viral quasispecies reconstruction, and a survey of state-of-the-art methods and future trends in microbiome analysis. Computational Methods for Next Generation Sequencing Data Analysis: Reviews computational techniques such as new combinatorial optimization methods, data structures, high performance computing, machine learning, and inference algorithms Discusses the mathematical and computational challenges in NGS technologies Covers NGS error correction, de novo genome transcriptome assembly, variant detection from NGS reads, and more This text is a reference for biomedical professionals interested in expanding their knowledge of computational techniques for NGS data analysis. The book is also useful for graduate and post-graduate students in bioinformatics.
Author :
Publisher :
ISBN 13 :
Total Pages : 116 pages
Book Rating : 4.3/5 (91 download)
Download or read book Human Genome written by and published by . This book was released on 1997 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kursad Turksen
Publisher : Springer Science & Business Media
ISBN 13 : 1588294978
Total Pages : 390 pages
Book Rating : 4.5/5 (882 download)
Download or read book Human Embryonic Stem Cell Protocols written by Kursad Turksen and published by Springer Science & Business Media. This book was released on 2006 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: "All of the electronic versions of illustrations in this book may be found on the Companion CD attached to the inside back cover ... compatible with both MAC and PC operating systems"--P. xv.
Author : Angel Carracedo
Publisher : Springer Science & Business Media
ISBN 13 : 1592598676
Total Pages : 282 pages
Book Rating : 4.5/5 (925 download)
Download or read book Forensic DNA Typing Protocols written by Angel Carracedo and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: A state-of-the-art collection of readily reproducible laboratory methods for DNA identity analysis, including Y chromosome haplotyping, mtDNA, and SNP typing. The book offers well-tested protocols for DNA quantification using real-time PCR on forensic samples and for the determination of the number of amelogenine gene copies. For forensic geneticists, there are readily reproducible methods for species identification, ancient DNA, and pharmacogenetics. Additional chapters address new applications in the forensic genetics lab, such a species identification or typing of CYP polymorphisms for the analysis of adverse to drugs.
Author : United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Oversight and Investigations
Publisher :
ISBN 13 :
Total Pages : 292 pages
Book Rating : 4.0/5 ( download)
Download or read book Human tissue samples written by United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Oversight and Investigations and published by . This book was released on 2006 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 652 pages
Book Rating : 4.F/5 ( download)
Download or read book Recombinant DNA Research written by and published by . This book was released on 1986 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt:
