Current Advances In Drug Delivery Through Fast Dissolving Disintegrating Dosage Forms

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Current Advances in Drug Delivery Through Fast Dissolving/Disintegrating Dosage Forms

Author : Vikas Anand Saharan
Publisher : Bentham Science Publishers
ISBN 13 : 1681084597
Total Pages : 453 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis Current Advances in Drug Delivery Through Fast Dissolving/Disintegrating Dosage Forms by : Vikas Anand Saharan

Download or read book Current Advances in Drug Delivery Through Fast Dissolving/Disintegrating Dosage Forms written by Vikas Anand Saharan and published by Bentham Science Publishers. This book was released on 2017-05-11 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fast Dissolving/Disintegrating Dosage Forms (FDDFs) have been commercially available since the late 1990s. FDDFs were initially available as orodispersible tablets, and later, as orodipsersible films for treating specific populations (pediatrics, geriatrics, and psychiatric patients). Granules, pellets and mini tablets are among latest additions to these dosage forms, which are still in the development pipeline. As drug delivery systems, FDDFs enable quicker onset of action, immediate drug delivery, and sometimes offer bioavailability benefits due to buccal/sublingual absorption. With time, FDDF have evolved to deliver drugs in a sustained and controlled manner. Their current market and application is increasing in demands with advances in age adapted dosage forms for different patients and changing regulatory requirements that warrant mandatory assessments of new drugs and drug products before commercial availability. This book presents detailed information about FDDFs from their inception to recent developments. Readers will learn about the technical details of various FDDF manufacturing methods, formulation aspects, evaluation and methods to conduct clinical studies. The authors also give examples of marketed fast disintegrating/dissolving drug products in US, Europe, Japan, and India. This reference is ideal for pharmacology students at all levels seeking information about this specific form of drug delivery and formulation.

Drug Delivery Research Advances

Author : Boris O. Mashkevich
Publisher : Nova Publishers
ISBN 13 : 9781600217326
Total Pages : 274 pages
Book Rating : 4.2/5 (173 download)

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Book Synopsis Drug Delivery Research Advances by : Boris O. Mashkevich

Download or read book Drug Delivery Research Advances written by Boris O. Mashkevich and published by Nova Publishers. This book was released on 2007 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug delivery is a term that refers to the delivery of a pharmaceutical compound to humans or animals. Most common methods of delivery include the preferred non-invasive oral (through the mouth), nasal, pneumonial (inhalation), and rectal routes. Many medications, however, can not be delivered using these routes because they might be susceptible to degradation or are not incorporated efficiently. For this reason many protein and peptide drugs have to be delivered by injection. For example, many immunisations are based on the delivery of protein drugs and are often done by injection. Current efforts in the area of drug delivery include the development of targeted delivery in which the drug is only active in the target area of the body (for example, in cancerous tissues) and sustained release formulations in which the drug is released over a period of time in a controlled manner from a formulation. This new book focuses on worldwide research on drug delivery and targeting at the molecular, cellular, and higher levels.

Pharmaceutical Dosage Forms and Drug Delivery

Author : Ram I. Mahato
Publisher : CRC Press
ISBN 13 : 1482253674
Total Pages : 690 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Pharmaceutical Dosage Forms and Drug Delivery by : Ram I. Mahato

Download or read book Pharmaceutical Dosage Forms and Drug Delivery written by Ram I. Mahato and published by CRC Press. This book was released on 2017-11-22 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, this third edition of Pharmaceutical Dosage Forms and Drug Delivery elucidates the basic principles of pharmaceutics, biopharmaceutics, dosage form design, and drug delivery – including emerging new biotechnology-based treatment modalities. The authors integrate aspects of physical pharmacy, chemistry, biology, and biopharmaceutics into drug delivery. This book highlights the increased attention that the recent spectacular advances in gene therapy and nanotechnology have brought to dosage form design and drug delivery. With the expiration of older patents and generic competition, the biopharmaceutical industry is evolving faster than ever. Apart from revising and updating existing chapters on the basic principles, this edition highlights the emerging emphasis on drug discovery, antibodies and antibody-drug conjugates as therapeutic moieties, individualized medicine including patient stratification strategies, targeted drug delivery, and the increasing role of modeling and simulation. Although there are numerous books on pharmaceutics and dosage forms, most cover different areas of the discipline and do not provide an integrated approach. The integrated approach of this book not only provides a singular perspective of the overall field, but also supplies a unified source of information for students, instructors and professionals, saving their time and money.

Pharmaceutical Dosage Forms and Drug Delivery

Author : Ram I. Mahato
Publisher : CRC Press
ISBN 13 : 1482253690
Total Pages : 773 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Pharmaceutical Dosage Forms and Drug Delivery by : Ram I. Mahato

Download or read book Pharmaceutical Dosage Forms and Drug Delivery written by Ram I. Mahato and published by CRC Press. This book was released on 2017-11-22 with total page 773 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, this third edition of Pharmaceutical Dosage Forms and Drug Delivery elucidates the basic principles of pharmaceutics, biopharmaceutics, dosage form design, and drug delivery – including emerging new biotechnology-based treatment modalities. The authors integrate aspects of physical pharmacy, chemistry, biology, and biopharmaceutics into drug delivery. This book highlights the increased attention that the recent spectacular advances in gene therapy and nanotechnology have brought to dosage form design and drug delivery. With the expiration of older patents and generic competition, the biopharmaceutical industry is evolving faster than ever. Apart from revising and updating existing chapters on the basic principles, this edition highlights the emerging emphasis on drug discovery, antibodies and antibody-drug conjugates as therapeutic moieties, individualized medicine including patient stratification strategies, targeted drug delivery, and the increasing role of modeling and simulation. Although there are numerous books on pharmaceutics and dosage forms, most cover different areas of the discipline and do not provide an integrated approach. The integrated approach of this book not only provides a singular perspective of the overall field, but also supplies a unified source of information for students, instructors and professionals, saving their time and money.

Recent Advances in Drug Delivery Systems

Author : James M Anderson
Publisher :
ISBN 13 : 9781461327462
Total Pages : 408 pages
Book Rating : 4.3/5 (274 download)

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Book Synopsis Recent Advances in Drug Delivery Systems by : James M Anderson

Download or read book Recent Advances in Drug Delivery Systems written by James M Anderson and published by . This book was released on 1984-05-31 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Melt Extrusion

Author : Michael A. Repka
Publisher : Springer Science & Business Media
ISBN 13 : 1461484324
Total Pages : 474 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Melt Extrusion by : Michael A. Repka

Download or read book Melt Extrusion written by Michael A. Repka and published by Springer Science & Business Media. This book was released on 2013-10-11 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides readers with the basic principles and fundamentals of extrusion technology and a detailed description of the practical applications of a variety of extrusion processes, including various pharma grade extruders. In addition, the downstream production of films, pellets and tablets, for example, for oral and other delivery routes, are presented and discussed utilizing melt extrusion. This book is the first of its kind that discusses extensively the well-developed science of extrusion technology as applied to pharmaceutical drug product development and manufacturing. By covering a wide range of relevant topics, the text brings together all technical information necessary to develop and market pharmaceutical dosage forms that meet current quality and regulatory requirements. As extrusion technology continues to be refined further, usage of extruder systems and the array of applications will continue to expand, but the core technologies will remain the same.

Drug Delivery to the Oral Cavity

Author : Tapash K. Ghosh
Publisher : CRC Press
ISBN 13 : 9780824782931
Total Pages : 448 pages
Book Rating : 4.7/5 (829 download)

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Book Synopsis Drug Delivery to the Oral Cavity by : Tapash K. Ghosh

Download or read book Drug Delivery to the Oral Cavity written by Tapash K. Ghosh and published by CRC Press. This book was released on 2005-02-28 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions from recognized authorities in industry, academia, and government, this reference presents the state-of-the-art in the testing, formulation, and clinical evaluation of intraoral drug delivery products-summarizing intraoral dosage forms in various stages of research, as well as products currently on the market.

Excipient Applications in Formulation Design and Drug Delivery

Author : Ajit S Narang
Publisher : Springer
ISBN 13 : 3319202065
Total Pages : 681 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Excipient Applications in Formulation Design and Drug Delivery by : Ajit S Narang

Download or read book Excipient Applications in Formulation Design and Drug Delivery written by Ajit S Narang and published by Springer. This book was released on 2015-10-07 with total page 681 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, emerging trends in the design and development of drug products have indicated ever greater need for integrated characterization of excipients and in-depth understanding of their roles in drug delivery applications. This book presents a concise summary of relevant scientific and mechanistic information that can aid the use of excipients in formulation design and drug delivery applications. Each chapter is contributed by chosen experts in their respective fields, which affords truly in-depth perspective into a spectrum of excipient-focused topics. This book captures current subjects of interest – with the most up to date research updates – in the field of pharmaceutical excipients. This includes areas of interest to the biopharmaceutical industry users, students, educators, excipient manufacturers, and regulatory bodies alike.

Polymer Gels

Author : Vijay Kumar Thakur
Publisher : Springer
ISBN 13 : 9811060835
Total Pages : 405 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Polymer Gels by : Vijay Kumar Thakur

Download or read book Polymer Gels written by Vijay Kumar Thakur and published by Springer. This book was released on 2018-08-07 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses a range of synthesis and characterization techniques that are critical for tailoring and broadening the various aspects of polymer gels, as well as the numerous advantages that polymer gel-based materials offer. It presents a comprehensive collection of chapters on the recent advances and developments in the science and fundamentals of both synthetic and natural polymer-based gels. Topics covered include: synthesis and structure of physically/chemically cross-linked polymer-gels/polymeric nanogels; gel formation through non-covalent cross-linking; molecular design and characterization; polysaccharide-based polymer gels: synthesis, characterization, and properties; modified polysaccharide gels: silica-based polymeric gels as platforms for the delivery of pharmaceuticals; gel-based approaches in genomic and proteomic sciences; emulgels in drug delivery; and organogels. The book provides a cutting-edge resource for researchers and scientists working in various fields involving polymers, biomaterials, bio-nanotechnology and functional materials.

Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems

Author : Ashok Katdare
Publisher : CRC Press
ISBN 13 : 1420004131
Total Pages : 452 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems by : Ashok Katdare

Download or read book Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems written by Ashok Katdare and published by CRC Press. This book was released on 2006-07-28 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: To facilitate the development of novel drug delivery systems and biotechnology-oriented drugs, the need for new excipients to be developed and approved continues to increase. Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems serves as a comprehensive source to improve understanding of excipients and forge new avenue

3D Printing of Pharmaceuticals

Author : Abdul W. Basit
Publisher : Springer
ISBN 13 : 3319907557
Total Pages : 240 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis 3D Printing of Pharmaceuticals by : Abdul W. Basit

Download or read book 3D Printing of Pharmaceuticals written by Abdul W. Basit and published by Springer. This book was released on 2018-08-06 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: 3D printing is forecast to revolutionise the pharmaceutical sector, changing the face of medicine development, manufacture and use. Potential applications range from pre-clinical drug development and dosage form design through to the fabrication of functionalised implants and regenerative medicine. Within clinical pharmacy practice, printing technologies may finally lead to the concept of personalised medicines becoming a reality. This volume aims to be the definitive resource for anyone thinking of developing or using 3D printing technologies in the pharmaceutical sector, with a strong focus on the translation of printing technologies to a clinical setting. This text brings together leading experts to provide extensive information on an array of 3D printing techniques, reviewing the current printing technologies in the pharmaceutical manufacturing supply chain, in particular, highlighting the state-of-the-art applications in medicine and discussing modern drug product manufacture from a regulatory perspective. This book is a highly valuable resource for a range of demographics, including academic researchers and the pharmaceutical industry, providing a comprehensive inventory detailing the current and future applications of 3D printing in pharmaceuticals. Abdul W. Basit is Professor of Pharmaceutics at the UCL School of Pharmacy, University College London. Abdul’s research sits at the interface between pharmaceutical science and gastroenterology, forging links between basic science and clinical outcomes. He leads a large and multidisciplinary research group, and the goal of his work is to further the understanding of gastrointestinal physiology by fundamental research. So far, this knowledge has been translated into the design of new technologies and improved disease treatments, many of which are currently in late-stage clinical trials. He has published over 350 papers, book chapters and abstracts and delivered more than 250 invited research presentations. Abdul is also a serial entrepreneur and has filed 25 patents and founded 3 pharmaceutical companies (Kuecept, Intract Pharma, FabRx). Abdul is a frequent speaker at international conferences, serves as a consultant to many pharmaceutical companies and is on the advisory boards of scientific journals, healthcare organisations and charitable bodies. He is the European Editor of the International Journal of Pharmaceutics. Abdul was the recipient of the Young Investigator Award in Pharmaceutics and Pharmaceutical Technology from the American Association of Pharmaceutical Scientists (AAPS) and is the only non-North American scientist to receive this award. He was also the recipient of the Academy of Pharmaceutical Sciences (APS) award. Simon Gaisford holds a Chair in Pharmaceutics and is Head of the Department of Pharmaceutics at the UCL School of Pharmacy, University College London. He has published 110 papers, 8 book chapters and 4 authored books. His research is focused on novel technologies for manufacturing medicines, particularly using ink-jet printing and 3D printing, and he is an expert in the physico-chemical characterisation of compounds and formulations with thermal methods and calorimetry.

Pharmaceutics

Author : Michael E. Aulton
Publisher :
ISBN 13 : 9780443055171
Total Pages : 679 pages
Book Rating : 4.0/5 (551 download)

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Book Synopsis Pharmaceutics by : Michael E. Aulton

Download or read book Pharmaceutics written by Michael E. Aulton and published by . This book was released on 2002 with total page 679 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive textbook covering the design of dosage forms and all aspects of drug delivery systems. 'Pharmaceutics' in its broadest sense is the 'art of the apothecary' or, in simple terms, pharmaceutical preparations. It remains a diverse subject in the pharmacy curriculum, encompassing design of drugs, their manufacture, and the elimination of micro-organisms from the products. This books encompasses all those areas and pays particular attention to the design of dosage forms and their manufacture.

Pharmaceutical Dosage Forms

Author : Larry L. Augsburger
Publisher : CRC Press
ISBN 13 : 9780824782894
Total Pages : 640 pages
Book Rating : 4.7/5 (828 download)

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Book Synopsis Pharmaceutical Dosage Forms by : Larry L. Augsburger

Download or read book Pharmaceutical Dosage Forms written by Larry L. Augsburger and published by CRC Press. This book was released on 1990-03-30 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Pharmaceutical Controlled Release Technology

Author : Donald L. Wise
Publisher : CRC Press
ISBN 13 : 1482289989
Total Pages : 903 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Handbook of Pharmaceutical Controlled Release Technology by : Donald L. Wise

Download or read book Handbook of Pharmaceutical Controlled Release Technology written by Donald L. Wise and published by CRC Press. This book was released on 2000-08-24 with total page 903 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Pharmaceutical Controlled Release Technology reviews the design, fabrication, methodology, administration, and classifications of various drug delivery systems, including matrices, and membrane controlled reservoir, bioerodible, and pendant chain systems. Contains cutting-edge research on the controlled delivery of biomolecules!

Hot-Melt Extrusion

Author : Dennis Douroumis
Publisher : John Wiley & Sons
ISBN 13 : 1118307879
Total Pages : 404 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Hot-Melt Extrusion by : Dennis Douroumis

Download or read book Hot-Melt Extrusion written by Dennis Douroumis and published by John Wiley & Sons. This book was released on 2012-04-24 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hot-melt extrusion (HME) - melting a substance and forcing it through an orifice under controlled conditions to form a new material - is an emerging processing technology in the pharmaceutical industry for the preparation of various dosage forms and drug delivery systems, for example granules and sustained release tablets. Hot-Melt Extrusion: Pharmaceutical Applications covers the main instrumentation, operation principles and theoretical background of HME. It then focuses on HME drug delivery systems, dosage forms and clinical studies (including pharmacokinetics and bioavailability) of HME products. Finally, the book includes some recent and novel HME applications, scale -up considerations and regulatory issues. Topics covered include: principles and die design of single screw extrusion twin screw extrusion techniques and practices in the laboratory and on production scale HME developments for the pharmaceutical industry solubility parameters for prediction of drug/polymer miscibility in HME formulations the influence of plasticizers in HME applications of polymethacrylate polymers in HME HME of ethylcellulose, hypromellose, and polyethylene oxide bioadhesion properties of polymeric films produced by HME taste masking using HME clinical studies, bioavailability and pharmacokinetics of HME products injection moulding and HME processing for pharmaceutical materials laminar dispersive & distributive mixing with dissolution and applications to HME technological considerations related to scale-up of HME processes devices and implant systems by HME an FDA perspective on HME product and process understanding improved process understanding and control of an HME process with near-infrared spectroscopy Hot-Melt Extrusion: Pharmaceutical Applications is an essential multidisciplinary guide to the emerging pharmaceutical uses of this processing technology for researchers in academia and industry working in drug formulation and delivery, pharmaceutical engineering and processing, and polymers and materials science. This is the first book from our brand new series Advances in Pharmaceutical Technology. Find out more about the series here.

Multiparticulate Drug Delivery

Author : Ali R. Rajabi-Siahboomi
Publisher : Springer
ISBN 13 : 1493970127
Total Pages : 396 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Multiparticulate Drug Delivery by : Ali R. Rajabi-Siahboomi

Download or read book Multiparticulate Drug Delivery written by Ali R. Rajabi-Siahboomi and published by Springer. This book was released on 2017-05-26 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by leading experts from academia, users and manufacturers, this book provides an authoritative account of the science and technology involved in multiparticulate drug delivery systems which offer superior clinical and technical advantages over many other specialized approaches in drug delivery. The book will cover market trends, potential benefits and formulation challenges for various types of multiparticulate systems. Drug solubility, dose, chemistry and therapeutic indications as well as excipient suitability coupled with manufacturing methods will be fully covered. Key approaches for taste-masking, delayed release and extended release of multiparticulates systems are of significant interest, especially their in-vivo and in-vitro performance. In addition, the principles of scale-up, QbD, and regulatory aspects of common materials used in this technology will be explained, as well as recent advances in materials and equipment enabling robust, flexible and cost-effective manufacture. Case studies illustrating best practices will also make the book a valuable resource to pharmaceutical scientists in industry and academia.

Particle Size Measurement

Author : Terence Allen
Publisher : Springer Science & Business Media
ISBN 13 : 9780412753305
Total Pages : 282 pages
Book Rating : 4.7/5 (533 download)

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Book Synopsis Particle Size Measurement by : Terence Allen

Download or read book Particle Size Measurement written by Terence Allen and published by Springer Science & Business Media. This book was released on 1996-12-31 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the fifth edition of the highly successful work first published in 1968, comprising two definitive volumes on particle characterisation. The first volume is devoted to sampling and particle size measurement, while surface area and pore size determination are reviewed in volume 2. Particle size and characterisation are central to understanding powder properties and behaviour. This book describes numerous potential measuring devices, how they operate and their advantages and disadvantages. It comprise a fully comprehensive treatise on the wide range of available equipment with an extensive literature survey, and a list of manufacturers and suppliers. The author's blend of academic and industrial experience results in a readable technical book with information on how to analyse, present, and extract useful information from data. This is an essential reference book for both industrial and academic research workers in a variety of areas including: pharmaceuticals, food science, pollution analysis and control, electronic materials, agricultural products, polymers, pigments and chemicals.