SARS-CoV-2 Spike Protein Convergent Evolution

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Author :
Publisher : Springer Nature
ISBN 13 : 3030873242
Total Pages : 140 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis SARS-CoV-2 Spike Protein Convergent Evolution by : Daniele Focosi

Download or read book SARS-CoV-2 Spike Protein Convergent Evolution written by Daniele Focosi and published by Springer Nature. This book was released on 2021-10-11 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the current knowledge of the globally circulating SARS-CoV-2 variants, highlights their distinct genetic characteristics and associated conformational changes in the viral spike protein, and profoundly discusses the mechanisms of convergent evolution that led to the rise of these mutated strains at different geographic regions during the Covid-19 pandemic. Furthermore, the book explores how these variants do and may impact the efficacy of established neutralizing antibody-based (nAb) vaccines and therapeutics by analysing latest in vivo and in vitro clinical data. Finally, the author discusses ways on how nAb Covid-19 treatment derived immune escape of SARS-CoV-2 could be minimized in the future.

Blue Marble Health

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Publisher : JHU Press
ISBN 13 : 1421420465
Total Pages : 224 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis Blue Marble Health by : Peter J. Hotez

Download or read book Blue Marble Health written by Peter J. Hotez and published by JHU Press. This book was released on 2016-09 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why do diseases of poverty afflict more people in wealthy countries than in the developing world? In 2011, Dr. Peter J. Hotez relocated to Houston to launch Baylor’s National School of Tropical Medicine. He was shocked to discover that a number of neglected diseases often associated with developing countries were widespread in impoverished Texas communities. Despite the United States’ economic prowess and first-world status, an estimated 12 million Americans living at the poverty level currently suffer from at least one neglected tropical disease, or NTD. Hotez concluded that the world’s neglected diseases—which include tuberculosis, hookworm infection, lymphatic filariasis, Chagas disease, and leishmaniasis—are born first and foremost of extreme poverty. In this book, Hotez describes a new global paradigm known as “blue marble health,” through which he asserts that poor people living in wealthy countries account for most of the world’s poverty-related illness. He explores the current state of neglected diseases in such disparate countries as Mexico, South Korea, Argentina, Australia, the United States, Japan, and Nigeria. By crafting public policy and relying on global partnerships to control or eliminate some of the world’s worst poverty-related illnesses, Hotez believes, it is possible to eliminate life-threatening disease while at the same time creating unprecedented opportunities for science and diplomacy. Clear, compassionate, and timely, Blue Marble Health is a must-read for leaders in global health, tropical medicine, and international development, along with anyone committed to helping the millions of people who are caught in the desperate cycle of poverty and disease.

Patent Landscape Report on Vaccines for Selected Infectious Diseases

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Author :
Publisher : WIPO
ISBN 13 : 9280521780
Total Pages : 185 pages
Book Rating : 4.2/5 (85 download)

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Book Synopsis Patent Landscape Report on Vaccines for Selected Infectious Diseases by : World Intellectual Property Organization

Download or read book Patent Landscape Report on Vaccines for Selected Infectious Diseases written by World Intellectual Property Organization and published by WIPO. This book was released on 2012-09-14 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scope of this report is to detect patterns of patenting activity and innovation in the area of vaccine research and manufacturing in order to facilitate the sourcing of vaccine technologies that could potentially be used in developing countries. Part I provides an overview of patenting activity in the area of vaccines by means of a statistical analysis. Part II focuses on the patenting related to vaccines for: streptococcus pneumonia conjugate vaccines; typhoid conjugate vaccines; and influenza vaccines. Each part of the report also includes a special focus on the patenting activity in Brazil, China and India.

COVID-19-Related Vaccines and Therapeutics :

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Author :
Publisher : WIPO
ISBN 13 : 9280533606
Total Pages : 83 pages
Book Rating : 4.2/5 (85 download)

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Book Synopsis COVID-19-Related Vaccines and Therapeutics : by : World Intellectual Property Organization

Download or read book COVID-19-Related Vaccines and Therapeutics : written by World Intellectual Property Organization and published by WIPO. This book was released on 2022-02-24 with total page 83 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the start of the COVID-19 pandemic there have been remarkable research and innovation efforts to fight the SARS-COV-2 virus and the related disease. This patent landscape report provides early observations on the patenting activity which took place in the field of COVID-19 vaccines and therapeutics, and compares results with clinical trial data for related candidate vaccines and drugs.

CDC Yellow Book 2018: Health Information for International Travel

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Author :
Publisher : Oxford University Press
ISBN 13 : 0190628634
Total Pages : 705 pages
Book Rating : 4.1/5 (96 download)

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Book Synopsis CDC Yellow Book 2018: Health Information for International Travel by : Centers for Disease Control and Prevention CDC

Download or read book CDC Yellow Book 2018: Health Information for International Travel written by Centers for Disease Control and Prevention CDC and published by Oxford University Press. This book was released on 2017-04-17 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.

Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis

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Author :
Publisher : Springer Nature
ISBN 13 : 3030022390
Total Pages : 334 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis by : Renato Alberto Sinico

Download or read book Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis written by Renato Alberto Sinico and published by Springer Nature. This book was released on 2019-09-13 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, written by well-known experts in the field, covers all aspects of Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis (AAV). The expression refers to a group of diseases, characterized by destruction and inflammation of small vessels. The clinical signs vary and affect several organs, such as the kidney, lung, skin, nervous system and others. The opening chapters give some historical hints, explain the genetic basis of the disease and provide insights into the pathogenesis derived from recent experimental studies and guides the reader through classification and nomenclature. A large part of the book is then devoted to a detailed description of the specific related diseases and their clinical presentations, the disease course, and potential complications. The advice regarding treatment is based on the best currently available evidence in this constantly evolving area. The book is part of Springer’s series Rare Diseases of the Immune System, which presents recently acquired knowledge on pathogenesis, diagnosis, and therapy with the aim of promoting a more holistic approach to these conditions. AAVs are systemic autoimmune diseases of unknown cause that affect small (to medium) sized blood vessels. They include granulomatosis with polyangiitis (formerly Wegener's granulomatosis), microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis (formerly Churg–Strauss syndrome). This volume will be an invaluable source of up-to-date information for all practitioners involved in the care of patients with these diseases.

COVID-19 Vaccines and Therapeutics

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Author :
Publisher : WIPO
ISBN 13 : 9280535307
Total Pages : 85 pages
Book Rating : 4.2/5 (85 download)

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Book Synopsis COVID-19 Vaccines and Therapeutics by : World Intellectual Property Organization

Download or read book COVID-19 Vaccines and Therapeutics written by World Intellectual Property Organization and published by WIPO. This book was released on 2023-04-20 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the start of the COVID-19 pandemic there have been remarkable research and innovation efforts to fight the SARS-CoV-2 virus and the COVID-19 disease. This report provides observations based on a comprehensive review of the patenting activity that took place in the field of COVID-19 vaccines and therapeutics and builds on the insights discussed in the first WIPO COVID-19 Patent Landscape Report published in March 2022.

Delineating Health and Health System: Mechanistic Insights into Covid 19 Complications

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Author :
Publisher : Springer Nature
ISBN 13 : 9811651051
Total Pages : 496 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Delineating Health and Health System: Mechanistic Insights into Covid 19 Complications by : R. C. Sobti

Download or read book Delineating Health and Health System: Mechanistic Insights into Covid 19 Complications written by R. C. Sobti and published by Springer Nature. This book was released on 2021-11-30 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the organ-specific systemic manifestations of COVID-19. The initial chapters of the book review the origin and evolution of the coronaviruses, followed by pathogenesis and immune response during COVID-19 infection. The book also provides insight into the role of angiotensin-converting enzyme 2 in the onset of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogenesis. It summarizes the neurological aspects of SARS-CoV2, including transmission pathways, mechanisms of invasion into the nervous system, and mechanisms of neurological disease. It also delineates the association of severe disease with high blood plasma levels of inflammatory cytokines and inflammatory markers in SARS-CoV-2 infection. Lastly, it discusses the perturbation of gut microbiota by SARS-CoV-2 and uncovers the potential risk of virus infection on reproductive health.

MERS-CoV

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Author :
Publisher : MDPI
ISBN 13 : 3039218506
Total Pages : 274 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis MERS-CoV by : Fang Li

Download or read book MERS-CoV written by Fang Li and published by MDPI. This book was released on 2019-12-12 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging zoonotic coronavirus. First identified in 2012, MERS-CoV has caused over 2460 infections and a fatality rate of about 35% in humans. Similar to severe acute respiratory syndrome coronavirus (SARS-CoV), MERS-CoV likely originated from bats; however, different from SARS-CoV, which potentially utilized palm civets as its intermediate hosts, MERS-CoV likely transmits to humans through dromedary camels. Animal models, such as humanized mice and nonhuman primates, have been developed for studying MERS-CoV infection. Currently, there are no vaccines and therapeutics approved for the prevention and treatment of MERS-CoV infection, although a number of them have been developed preclinically or tested clinically. This book covers one editorial and 16 articles (including seven review articles and nine original research papers) written by researchers working in the field of MERS-CoV. It describes the following three main aspects: (1) MERS-CoV epidemiology, transmission, and pathogenesis; (2) current progress on MERS-CoV animal models, vaccines, and therapeutics; and (3) challenges and future prospects for MERS-CoV research. Overall, this book will help researchers in the MERS-CoV field to further advance their work on the virus. It also has important implications for other coronaviruses as well as viruses outside the coronavirus family with pandemic potentials.

World Health Statistics 2009

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Author :
Publisher : World Health Organization
ISBN 13 : 9241563818
Total Pages : 150 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis World Health Statistics 2009 by : World Health Organization

Download or read book World Health Statistics 2009 written by World Health Organization and published by World Health Organization. This book was released on 2009 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: World Health Statistics 2009 contains WHO's annual compilation of data from its 193 member states, and includes a summary of progress towards the health-related millennium development goals and targets. This edition also contains a new section on reported cases of selected infectious diseases. It provides a comprehensive summary of the current status of national health and health systems including; mortality and burden of disease, causes of death, reported infectious diseases, health service coverage, risk factors, health systems resources, health expenditures, inequities and demographic and socioeconomic statistics. The section on inequities presents statistics on the distribution of selected health outcomes and interventions within countries, disaggregated by sex, age, urban and rural settings, wealth, and educational level. WHO presents World Health Statistics 2009 as an integral part of its ongoing effort to inform better measures of population health and national health systems.

Viruses as Therapeutics

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Author :
Publisher :
ISBN 13 : 9781071610145
Total Pages : pages
Book Rating : 4.6/5 (11 download)

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Book Synopsis Viruses as Therapeutics by : Alexandra R. Lucas

Download or read book Viruses as Therapeutics written by Alexandra R. Lucas and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Prevention And Control Of Covid-19

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Author :
Publisher : World Scientific
ISBN 13 : 9811220514
Total Pages : 72 pages
Book Rating : 4.8/5 (112 download)

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Book Synopsis Prevention And Control Of Covid-19 by :

Download or read book Prevention And Control Of Covid-19 written by and published by World Scientific. This book was released on 2020-04-15 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shanghai COVID-19 Medical Treatment Expert Team edits this timely guide for effective prevention and control of COVID-19. Readers will obtain useful guidance on prevention and control of COVID-19 in different places ranging from homes, outdoors, workplaces, etc. You will know 'What is the purpose and significance of home quarantine?', ' When do you need to wear a mask?', 'How should you wash your hands?', 'Do you need to wear a mask in an elevator?', 'What foods are safe to eat and what are not?', 'How to deal with express parcels from major epidemic areas or other areas?' and many other useful tips.Related Link(s)

Antibody Patenting

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Publisher : Kluwer Law International B.V.
ISBN 13 : 9403510803
Total Pages : 516 pages
Book Rating : 4.4/5 (35 download)

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Book Synopsis Antibody Patenting by : Jürgen Meier

Download or read book Antibody Patenting written by Jürgen Meier and published by Kluwer Law International B.V.. This book was released on 2019-08-08 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibodies have revolutionized medicine and biotechnology, and have become indispensable tools in therapy, diagnostics, analytics, and research. Therapeutic antibodies, for example, have come to dominate the ranks of blockbuster drugs, currently accounting for 10 out of the top 15 best-selling medicines. At the same time, a body of case law dealing specifically with the patentability of antibody-related inventions and the enforcement of antibody patents has emerged in major jurisdictions. The, at times, significant divergences between different jurisdictions have been compounded by recent decisions in the United States, most notably Amgen v. Sanofi, 872 F.3d 1367 (Fed. Cir. 2017), which have severely curtailed the possibilities to obtain broad antibody patents. It is therefore essential to understand how antibody inventions are assessed in different jurisdictions in order to secure an optimal patent protection and to successfully enforce such patents. This book provides practitioners with a comprehensive resource elucidating all aspects of the patenting of antibodies from initial drafting and prosecution to enforcement, using a country-by-country format. It covers 23 of the most important IP jurisdictions worldwide – i.e., the European Patent Office, France, Germany, Italy, the Netherlands, Poland, Spain, Switzerland, the United Kingdom, Israel, the United States of America, Argentina, the Andean Community (Bolivia, Colombia, Ecuador, and Peru), Brazil, Canada, Chile, Mexico, China, India, Japan, Singapore, South Korea, and Australia. The 35 contributors to this book, all distinguished experts in this field, provide clear and practice-oriented advice on a range of topics including: – Which types of antibody inventions are patent-eligible? – Which types of functional and structural features are accepted for claiming antibodies? – What needs to be considered when defining antibodies in terms of their antigen, target affinity, binding specificity, epitope, competitive binding and other characteristics in relation to reference antibodies, as well as their effects on the target? – Which pitfalls must be avoided when defining amino acid sequences, chemical modifications or glycosylation patterns, and when relying on cell line deposits? – Which breadth of claims is accepted for antibody inventions, and what experimental support is required? – Which specific medical applications of antibodies can be claimed? – How is inventive step assessed in the specific case of antibody inventions? – What has to be considered when enforcing antibody patents, including in relation to biosimilars as well as the doctrine of equivalence? All chapters follow the same structure, which makes this book easily accessible and allows a direct comparison between different jurisdictions. Practitioners will find the much-needed tools and guidance to secure the best possible patent protection for antibody inventions in 23 of the most important jurisdictions worldwide. This book is the fifth volume in the AIPPI Law Series which has been established together with the International Association for the Protection of Intellectual Property (AIPPI), a non-affiliated, non-profit organization dedicated to improving and promoting the protection of intellectual property at both national and international levels.

Guidelines for Preparing Patent Landscape Reports

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Author :
Publisher : WIPO
ISBN 13 : 9280525298
Total Pages : 131 pages
Book Rating : 4.2/5 (85 download)

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Book Synopsis Guidelines for Preparing Patent Landscape Reports by : World Intellectual Property Organization

Download or read book Guidelines for Preparing Patent Landscape Reports written by World Intellectual Property Organization and published by WIPO. This book was released on 2015-08-24 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: These Guidelines are designed both for general users of patent information, as well as for those involved in producing Patent Landscape Reports (PLRs). They provide step-by-step instructions on how to prepare a PLR, as well as background information such as objectives, patent analytics, concepts and frameworks.

Canadian Immunization Guide

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Publisher :
ISBN 13 : 9780660193922
Total Pages : 392 pages
Book Rating : 4.1/5 (939 download)

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Book Synopsis Canadian Immunization Guide by : Canada. Comité consultatif national de l'immunisation

Download or read book Canadian Immunization Guide written by Canada. Comité consultatif national de l'immunisation and published by . This book was released on 2006 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: The seventh edition of the Canadian Immunization Guide was developed by the National Advisory Committee on Immunization (NACI), with the support ofthe Immunization and Respiratory Infections Division, Public Health Agency of Canada, to provide updated information and recommendations on the use of vaccines in Canada. The Public Health Agency of Canada conducted a survey in 2004, which confi rmed that the Canadian Immunization Guide is a very useful and reliable resource of information on immunization.

Private Power, Public Law

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Author :
Publisher : Cambridge University Press
ISBN 13 : 9780521525398
Total Pages : 244 pages
Book Rating : 4.5/5 (253 download)

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Book Synopsis Private Power, Public Law by : Susan K. Sell

Download or read book Private Power, Public Law written by Susan K. Sell and published by Cambridge University Press. This book was released on 2003 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analysis of the power of multinational corporations in moulding international law on intellectual property rights.

Patent Landscape Report on Palm Oil Production and Waste Treatment Technologies

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Author :
Publisher : WIPO
ISBN 13 : 9280526960
Total Pages : 124 pages
Book Rating : 4.2/5 (85 download)

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Book Synopsis Patent Landscape Report on Palm Oil Production and Waste Treatment Technologies by : World Intellectual Property Organization

Download or read book Patent Landscape Report on Palm Oil Production and Waste Treatment Technologies written by World Intellectual Property Organization and published by WIPO. This book was released on with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report provides an overview of the global patent landscape in the area of palm oil production and waste exploitation, and includes national patent applications from Malaysia. It covers patenting activity related to technologies in production of palm oil and palm kernel oil, and treatment of waste from palm oil production.