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The AGT Cytogenetics Laboratory Manual

Author : Marilyn S. Arsham
Publisher : John Wiley & Sons
ISBN 13 : 1119061288
Total Pages : 2226 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis The AGT Cytogenetics Laboratory Manual by : Marilyn S. Arsham

Download or read book The AGT Cytogenetics Laboratory Manual written by Marilyn S. Arsham and published by John Wiley & Sons. This book was released on 2017-03-03 with total page 2226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cytogenetics is the study of chromosome morphology, structure, pathology, function, and behavior. The field has evolved to embrace molecular cytogenetic changes, now termed cytogenomics. Cytogeneticists utilize an assortment of procedures to investigate the full complement of chromosomes and/or a targeted region within a specific chromosome in metaphase or interphase. Tools include routine analysis of G-banded chromosomes, specialized stains that address specific chromosomal structures, and molecular probes, such as fluorescence in situ hybridization (FISH) and chromosome microarray analysis, which employ a variety of methods to highlight a region as small as a single, specific genetic sequence under investigation. The AGT Cytogenetics Laboratory Manual, Fourth Edition offers a comprehensive description of the diagnostic tests offered by the clinical laboratory and explains the science behind them. One of the most valuable assets is its rich compilation of laboratory-tested protocols currently being used in leading laboratories, along with practical advice for nearly every area of interest to cytogeneticists. In addition to covering essential topics that have been the backbone of cytogenetics for over 60 years, such as the basic components of a cell, use of a microscope, human tissue processing for cytogenetic analysis (prenatal, constitutional, and neoplastic), laboratory safety, and the mechanisms behind chromosome rearrangement and aneuploidy, this edition introduces new and expanded chapters by experts in the field. Some of these new topics include a unique collection of chromosome heteromorphisms; clinical examples of genomic imprinting; an example-driven overview of chromosomal microarray; mathematics specifically geared for the cytogeneticist; usage of ISCN’s cytogenetic language to describe chromosome changes; tips for laboratory management; examples of laboratory information systems; a collection of internet and library resources; and a special chapter on animal chromosomes for the research and zoo cytogeneticist. The range of topics is thus broad yet comprehensive, offering the student a resource that teaches the procedures performed in the cytogenetics laboratory environment, and the laboratory professional with a peer-reviewed reference that explores the basis of each of these procedures. This makes it a useful resource for researchers, clinicians, and lab professionals, as well as students in a university or medical school setting.

Microbiology

Author : Nina Parker
Publisher :
ISBN 13 : 9781938168147
Total Pages : 1301 pages
Book Rating : 4.1/5 (681 download)

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Book Synopsis Microbiology by : Nina Parker

Download or read book Microbiology written by Nina Parker and published by . This book was released on 2016-05-30 with total page 1301 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter. Microbiology's art program enhances students' understanding of concepts through clear and effective illustrations, diagrams, and photographs. Microbiology is produced through a collaborative publishing agreement between OpenStax and the American Society for Microbiology Press. The book aligns with the curriculum guidelines of the American Society for Microbiology."--BC Campus website.

Chromosome Analysis Protocols

Author : John R. Gosden
Publisher : Springer Science & Business Media
ISBN 13 : 1592595162
Total Pages : 508 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Chromosome Analysis Protocols by : John R. Gosden

Download or read book Chromosome Analysis Protocols written by John R. Gosden and published by Springer Science & Business Media. This book was released on 2008-02-02 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromosomes, as the genetic vehicles, provide the basic material for a large proportion of genetic investigations, from the construction of gene maps and models of chromosome organization, to the inves tigation of gene function and dysfunction. The study of chromosomes has developed in parallel with other aspects of molecular genetics, beginning with the first preparations of chromosomes from animal cells, through the development of banding techniques, which permitted the unequivocal identification of each chromosome in a karyotype, to the present analytical methods of molecular cytogenetics. Although some of these techniques have been in use for many years, and can be learned relatively easily, most published scientific reports—as a result of pressure on space from editors, and the response to that pressure by authors—contain little in the way of technical detail, and thus are rarely adequate for a researcher hoping to find all the necessary information to embark on a method from scratch. A new user needs not only a detailed description of the methods, but also some help with problem solving and sorting out the difficulties en countered in handling any biological system. This was the require ment to which the series Methods in Molecular Biology is addressed, and Chromosome Analysis Protocols forms a part of this series.

Microbiology

Author : Holly Ahern
Publisher :
ISBN 13 : 9781942341536
Total Pages : 140 pages
Book Rating : 4.3/5 (415 download)

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Book Synopsis Microbiology by : Holly Ahern

Download or read book Microbiology written by Holly Ahern and published by . This book was released on 2018-05-22 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a group of organisms that are too small to see and best known for being agents of disease and death, microbes are not always appreciated for the numerous supportive and positive contributions they make to the living world. Designed to support a course in microbiology, Microbiology: A Laboratory Experience permits a glimpse into both the good and the bad in the microscopic world. The laboratory experiences are designed to engage and support student interest in microbiology as a topic, field of study, and career. This text provides a series of laboratory exercises compatible with a one-semester undergraduate microbiology or bacteriology course with a three- or four-hour lab period that meets once or twice a week. The design of the lab manual conforms to the American Society for Microbiology curriculum guidelines and takes a ground-up approach -- beginning with an introduction to biosafety and containment practices and how to work with biological hazards. From there the course moves to basic but essential microscopy skills, aseptic technique and culture methods, and builds to include more advanced lab techniques. The exercises incorporate a semester-long investigative laboratory project designed to promote the sense of discovery and encourage student engagement. The curriculum is rigorous but manageable for a single semester and incorporates best practices in biology education.

Immunochemical Protocols

Author : John Pound
Publisher : Springer Science & Business Media
ISBN 13 : 1592592570
Total Pages : 501 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Immunochemical Protocols by : John Pound

Download or read book Immunochemical Protocols written by John Pound and published by Springer Science & Business Media. This book was released on 2008-02-03 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: This much anticipated second edition provides a user-friendly, up-to-date handbook of reliable immunochemical techniques optimized for molecular biologists. It covers the breadth of relevant established methods from protein blotting and immunoassays through to visualization of cellular antigens and in situ hybridization, each with their latest refinements. Protocols for the production and purification of important classes of immunochemical reagents are also provided, including "conventional" and recombinant antibodies, fusion proteins and their various conjugates. This book will open the door to a new generation of immunochemical reagents with exciting possibilities.

In Situ Molecular Pathology and Co-expression Analyses

Author : Gerard J. Nuovo
Publisher : Academic Press
ISBN 13 : 0128206543
Total Pages : 422 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis In Situ Molecular Pathology and Co-expression Analyses by : Gerard J. Nuovo

Download or read book In Situ Molecular Pathology and Co-expression Analyses written by Gerard J. Nuovo and published by Academic Press. This book was released on 2020-09-03 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Major advancements in the field of in situ molecular pathology have occurred since publication of the first edition. In Situ Molecular Pathology and Co-expression Analyses, Second Edition, continues to teach both the molecular basis for the improvements and the actual protocols. This is the unique feature that separates it from the pack of other "cook-book" type approaches. The fields of in situ hybridization and immunohistochemistry have expanded rapidly where computer-based analyses systems have greatly expanded the power of these methods. Further, knowledge of the marked improvements in the reagents themselves since the first edition can make the difference of excellent versus misleading data. The automated platforms require that researchers and diagnostic biomedical investigators have a good understanding of the basics of in situ based tests, protocols, and biochemistry for troubleshooting in order to maximize the use of these platforms. This second edition focuses attention on straightforward protocols used to simultaneously detect two or more proteins/nucleic acids within intact tissue by doing co-expression analyses. Practicing molecular pathologists, diagnostic pathologists, laboratory directors, and toxicologists, as well as clinicians and researchers in training, will benefit from this clear presentation of protocols and theoretical framework. Data derived from in situ hybridization and immunohistochemistry. - Explains the theory and foundation of immunohistochemistry and in situ hybridization and presents easy-to-follow experimental protocols with tricks of the trade - Includes two new chapters: Recent improvements in immunohistochemistry and in situ hybridization, Quality control for immunohistochemistry and in situ hybridization: How to know if the color change is signal or background - The second edition also includes a detailed test to help one learn the basics of histologic interpretation of tissues and a separate detailed test in how to differentiate signal from background - Includes chapter-ending summaries of Key Points to Remember, bringing beginners up to speed with any seasoned veteran in the field - Thoughtfully tackles the molecular basis if IHC and ISH, along with application of that knowledge to improving the techniques is significant

Cell Cycle - Materials and Methods

Author : Michele Pagano
Publisher : Springer Science & Business Media
ISBN 13 : 9783540580669
Total Pages : 324 pages
Book Rating : 4.5/5 (86 download)

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Book Synopsis Cell Cycle - Materials and Methods by : Michele Pagano

Download or read book Cell Cycle - Materials and Methods written by Michele Pagano and published by Springer Science & Business Media. This book was released on 1995-12-12 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: During their lifetime, especially when growing and dividing, cells go through various steps of the cell cycle. Knowledge of the individual steps of the cell cycle will help us understand the development of a variety of diseases better, including cancer, and also to design new drugs against it. New techniques for studying the molecular basis of these processes have recently been developed and are described in detail in this manual. A glossary helps the reader to cope with the complex cell cycle terminology.

Theory and Practice of Histological Techniques

Author : John D. Bancroft
Publisher : Elsevier Health Sciences
ISBN 13 : 0443102791
Total Pages : 742 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Theory and Practice of Histological Techniques by : John D. Bancroft

Download or read book Theory and Practice of Histological Techniques written by John D. Bancroft and published by Elsevier Health Sciences. This book was released on 2008-01-01 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt: This leading reference work on histological techniques is an essential and invaluable resource no matter what part you play in histological preparations and applications, whether you're a student or a highly experienced laboratory professional.

Stain Technology

Author :
Publisher :
ISBN 13 :
Total Pages : 160 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Stain Technology by :

Download or read book Stain Technology written by and published by . This book was released on 1926 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Jones Strain-Counterstrain

Author : Lawrence H. Jones
Publisher :
ISBN 13 : 9780964513549
Total Pages : 0 pages
Book Rating : 4.5/5 (135 download)

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Book Synopsis Jones Strain-Counterstrain by : Lawrence H. Jones

Download or read book Jones Strain-Counterstrain written by Lawrence H. Jones and published by . This book was released on 1995 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Image Analysis in Histology

Author : Richard Wootton
Publisher : CUP Archive
ISBN 13 : 9780521434829
Total Pages : 468 pages
Book Rating : 4.4/5 (348 download)

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Book Synopsis Image Analysis in Histology by : Richard Wootton

Download or read book Image Analysis in Histology written by Richard Wootton and published by CUP Archive. This book was released on 1995-05-11 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a timely and useful introduction to the theory and practical application of image analysis in histology. This powerful research technique can be used to detect not only stored products in a cell (immunocytochemistry) but the synthetic machinery and the genes that control it (in situ hybridisation), as well as the specific binding sites that act as receptors for a molecule following its release (in vitro autoradiography). The book provides a good introduction for beginners before looking in greater detail at more advanced material in selected areas. The volume highlights the importance of technique in gathering quantitative information. The book is divided into four sections: introductory material, image acquisition, image processing, and applications. The applications areas include quantitative immunochemistry, quantification of nerves and neurotransmitters and automated grain counting in in situ hybridisation histochemistry.

Amyloid and Related Disorders

Author : Maria M. Picken
Publisher : Humana Press
ISBN 13 : 3319192949
Total Pages : 536 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Amyloid and Related Disorders by : Maria M. Picken

Download or read book Amyloid and Related Disorders written by Maria M. Picken and published by Humana Press. This book was released on 2015-08-17 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this text presents an overview of the most recent developments in this area including clinical presentation, etiology, pathogenesis, and differential diagnosis. The rationale for various therapies, including transplantation, is discussed and tissue diagnosis (its pitfalls and strategies for avoiding them) and laboratory support are included. The involvement of all major organ systems including renal/genitourinary, cardiac, gastrointestinal, pulmonary, peripheral nerve/central nervous system, soft tissue, skin, lymph node/spleen and bone marrow pathology is also covered. Amyloid and Related Disorders, Second Edition will be invaluable to specialized and general pathologists as well as cytopathologists. Other medical professionals may also benefit from this concise update on the systemic amyloidoses.

Imaging and Spectroscopic Analysis of Living Cells

Author : P. Michael Conn
Publisher : Academic Press
ISBN 13 : 0123884489
Total Pages : 594 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Imaging and Spectroscopic Analysis of Living Cells by : P. Michael Conn

Download or read book Imaging and Spectroscopic Analysis of Living Cells written by P. Michael Conn and published by Academic Press. This book was released on 2012-02 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Methods in Enzymology is the second of three parts looking at current methodology for the imaging and spectroscopic analysis of live cells. The chapters provide hints and tricks not available in primary research publications. It is an invaluable resource for academics, researchers and students alike. Expert authors who are leaders in the field Extensively referenced and useful figures and tables Provides hints and tricks to facilitate reproduction of methods

Proceedings of the section of sciences

Author : Koninklijke Nederlandse Akademie van Wetenschappen. Afdeling Natuurkunde
Publisher :
ISBN 13 :
Total Pages : 822 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Proceedings of the section of sciences by : Koninklijke Nederlandse Akademie van Wetenschappen. Afdeling Natuurkunde

Download or read book Proceedings of the section of sciences written by Koninklijke Nederlandse Akademie van Wetenschappen. Afdeling Natuurkunde and published by . This book was released on 1912 with total page 822 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Gastric Cancer In The Precision Medicine Era

Author : Vincenzo Canzonieri
Publisher : Springer
ISBN 13 : 3030048616
Total Pages : 259 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Gastric Cancer In The Precision Medicine Era by : Vincenzo Canzonieri

Download or read book Gastric Cancer In The Precision Medicine Era written by Vincenzo Canzonieri and published by Springer. This book was released on 2019-05-02 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastric cancer is one of the most common and potentially lethal gastrointestinal malignancy, but it is now at the forefront of modern oncology due to new discoveries. In recent years, the field of gastric cancer has been transformed by many notable developments in both the diagnostic area and the therapeutic strategies. The main aim of the text is to propose a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for oncologists, pathologists, surgeons and researchers with an interest in gastric cancer. The first chapters will review the interplay between pathogens and especially H. pylori, inflammation, genomic instability, and tumorigenesis. Secondly, an exhaustive overview of the diagnosis of gastric cancer from a clinical/endoscopic and pathologic perspectives will be illustrated. Two specific chapters will deal with tissue and serum biomarkers with an important role in diagnosis as well as prognostic and predictive markers of response to specific therapy. A central section of the book will focus on treatment options available today for patients. Surgery is the cornerstone of treatment for gastric cancer; however, the prognosis of patients with locally advanced disease is still poor even after curative resection. Therefore, in order to improve the prognosis of patients, especially with advanced stage, a multimodal strategy is advisable and is thoroughly addressed in the appropriate section. With the advent of next-generation sequencing and new preclinical model technologies, the genomic landscape of gastric cancer has been delineated and molecular characterizations finalized to novel therapeutic targets of each molecular subtype have been identified. These advances are making it feasible to integrate clinical and phenotype-based diagnostic and therapeutic methods and are described in a dedicated section. The text will conclude with chapters focusing on the future direction of gastric cancer research in the precision medicine era: an in-depth analysis of non-coding RNAs and their role in gastric cancer, the impact of immunomodulation/immunotherapy and the perspectives of nano-medicine will be finally proposed to the audience. A brief review of the existing literature addressing the above mentioned topics will be present in each chapter. This text will serve as a useful resource for physicians and researchers dealing with, and interested in, this challenging malignancy. It will provide a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters will be written by experts in their fields and will include the most up to date scientific and clinical information.

Color Atlas of Medical Bacteriology

Author : Luis M. de la Maza
Publisher : John Wiley & Sons
ISBN 13 : 1683670485
Total Pages : 464 pages
Book Rating : 4.6/5 (836 download)

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Book Synopsis Color Atlas of Medical Bacteriology by : Luis M. de la Maza

Download or read book Color Atlas of Medical Bacteriology written by Luis M. de la Maza and published by John Wiley & Sons. This book was released on 2020-05-12 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique visual reference presents more than 750 brilliant, four-color images of bacterial isolates commonly encountered in diagnostic microbiology and the methods used to identify them, including microscopic and phenotypic characteristics, colony morphology, and biochemical properties. Chapters cover the most important bacterial pathogens and related organisms, including updated taxonomy, epidemiology, pathogenicity, laboratory and antibiotic susceptibility testing, and molecular biology methodology Tables summarize and compare key biochemical reactions and other significant characteristics New to this edition is a separate chapter covering the latest developments in total laboratory automation The comprehensive chapter on stains, media, and reagents is now augmented with histopathology images A new Fast Facts chapter presents tables that summarize and illustrate the most significant details for some of the more commonly encountered organisms For the first time, this easy-to-use atlas is available digitally for enhanced searching. Color Atlas of Medical Bacteriology remains the most valuable illustrative supplement for lectures and laboratory presentations, as well as for laboratorians, clinicians, students, and anyone interested in diagnostic medical bacteriology.

Journal of the National Cancer Institute

Author :
Publisher :
ISBN 13 :
Total Pages : 1248 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Journal of the National Cancer Institute by :

Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 2000 with total page 1248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each issue is packed with extensive news about important cancer related science, policy, politics and people. Plus, there are editorials and reviews by experts in the field, book reviews, and commentary on timely topics.