Correlation-based network analysis of cancer metabolism

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Publisher : Springer
ISBN 13 : 1493906151
Total Pages : 67 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Correlation-based network analysis of cancer metabolism by : Emily G. Armitage

Download or read book Correlation-based network analysis of cancer metabolism written by Emily G. Armitage and published by Springer. This book was released on 2014-05-12 with total page 67 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the rise of systems biology as an approach in biochemistry research, using high throughput techniques such as mass spectrometry to generate metabolic profiles of cancer metabolism is becoming increasingly popular. There are examples of cancer metabolic profiling studies in the academic literature; however they are often only in journals specific to the metabolomics community. This book will be particularly useful for post-graduate students and post-doctoral researchers using this pioneering technique of network-based correlation analysis. The approach can be adapted to the analysis of any large scale metabolic profiling experiment to answer a range of biological questions in a range of species or for a range of diseases.

The Heterogeneity of Cancer Metabolism

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Publisher : Springer
ISBN 13 : 331977736X
Total Pages : 186 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis The Heterogeneity of Cancer Metabolism by : Anne Le

Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

NMR-based Metabolomics

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Publisher : Royal Society of Chemistry
ISBN 13 : 184973643X
Total Pages : 384 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis NMR-based Metabolomics by : Hector C Keun

Download or read book NMR-based Metabolomics written by Hector C Keun and published by Royal Society of Chemistry. This book was released on 2018-01-17 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the state of the art in the application of NMR spectroscopy to metabolomics and will be a key title for researchers and practitioners.

Gene Network Inference

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Publisher : Springer Science & Business Media
ISBN 13 : 3642451616
Total Pages : 135 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Gene Network Inference by : Alberto Fuente

Download or read book Gene Network Inference written by Alberto Fuente and published by Springer Science & Business Media. This book was released on 2014-01-03 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents recent methods for Systems Genetics (SG) data analysis, applying them to a suite of simulated SG benchmark datasets. Each of the chapter authors received the same datasets to evaluate the performance of their method to better understand which algorithms are most useful for obtaining reliable models from SG datasets. The knowledge gained from this benchmarking study will ultimately allow these algorithms to be used with confidence for SG studies e.g. of complex human diseases or food crop improvement. The book is primarily intended for researchers with a background in the life sciences, not for computer scientists or statisticians.

AACR 2018 Proceedings: Abstracts 3028-5930

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Publisher : CTI Meeting Technology
ISBN 13 : 1370247702
Total Pages : pages
Book Rating : 4.3/5 (72 download)

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Book Synopsis AACR 2018 Proceedings: Abstracts 3028-5930 by : American Association for Cancer Research

Download or read book AACR 2018 Proceedings: Abstracts 3028-5930 written by American Association for Cancer Research and published by CTI Meeting Technology. This book was released on 2018-04-10 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Network Theory and Agent-Based Modeling in Economics and Finance

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Publisher : Springer Nature
ISBN 13 : 9811383197
Total Pages : 458 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Network Theory and Agent-Based Modeling in Economics and Finance by : Anindya S. Chakrabarti

Download or read book Network Theory and Agent-Based Modeling in Economics and Finance written by Anindya S. Chakrabarti and published by Springer Nature. This book was released on 2019-10-23 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest findings on network theory and agent-based modeling of economic and financial phenomena. In this context, the economy is depicted as a complex system consisting of heterogeneous agents that interact through evolving networks; the aggregate behavior of the economy arises out of billions of small-scale interactions that take place via countless economic agents. The book focuses on analytical modeling, and on the econometric and statistical analysis of the properties emerging from microscopic interactions. In particular, it highlights the latest empirical and theoretical advances, helping readers understand economic and financial networks, as well as new work on modeling behavior using rich, agent-based frameworks. Innovatively, the book combines observational and theoretical insights in the form of networks and agent-based models, both of which have proved to be extremely valuable in understanding non-linear and evolving complex systems. Given its scope, the book will capture the interest of graduate students and researchers from various disciplines (e.g. economics, computer science, physics, and applied mathematics) whose work involves the domain of complexity theory.

Yeast Systems Biology

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Publisher : Humana Press
ISBN 13 : 9781617791727
Total Pages : 0 pages
Book Rating : 4.7/5 (917 download)

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Book Synopsis Yeast Systems Biology by : Juan I. Castrillo

Download or read book Yeast Systems Biology written by Juan I. Castrillo and published by Humana Press. This book was released on 2011-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Biology aims at deciphering the genotype-phenotype relationships at the levels of genes, transcripts (RNAs), peptides, proteins, metabolites, and environmental factors participating in complex cellular networks in order to reveal the mechanisms and principles governing the behavior of complex biological systems. Yeast Systems Biology: Methods and Protocols presents an up-to-date view of the optimal characteristics of the yeast Saccharomyces cerevisiae as a model eukaryote, perspective on the latest experimental and computational techniques for systems biology studies, most of which were first designed for and validated in yeast, and selected examples of yeast systems biology studies and their applications in biotechnology and medicine. These experiments under controlled conditions can uncover the complexity and interplay of biological networks with their dynamics, basic principles of internal organization, and balanced orchestrated functions between organelles in direct interaction with the environment as well as the characterization of short and long-term effects of perturbations and dysregulation of networks that may illuminate the origin of complex human diseases. Written for the highly successful Methods in Molecular BiologyTM series, this volume contains the kind of detailed description and implementation advice that is crucial for getting optimal results. Practical and cutting-edge, Yeast Systems Biology: Methods and Protocols serves researchers interested in comprehensive systems biology strategies in well-defined model systems with specific objectives as well as a better knowledge of the latest post-genomic strategies at all ‘omic levels and computational approaches towards analysis, integration, and modeling of biological systems, from single-celled organisms to higher eukaryotes.

Frontiers in Drug Design & Discovery

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Publisher : Bentham Science Publishers
ISBN 13 : 1681081652
Total Pages : 313 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis Frontiers in Drug Design & Discovery by : Atta-ur-Rahman

Download or read book Frontiers in Drug Design & Discovery written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2016-05-18 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Drug Design and Discovery is an eBook series devoted to publishing the latest and the most important advances in drug design and discovery. Eminent scientists have contributed chapters focused on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. This eBook series should prove to be of interest to all pharmaceutical scientists who are involved in research in drug design and discovery and who wish to keep abreast of rapid and important developments in the field. The seventh volume of this series brings together seven reviews covering chemotherapeutic agents, antimicrobials and phytochemicals. Some topics included in this volume are: 1. Metabolic pathways and chemotherapy drugs 2. Cardiotoxicity of cancer chemotherapy 3. Nanotherapeutics for infectious diseases 4. Natural sources of angiogenesis inhibitors …and much more.

Plant Metabolomics

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Publisher : Springer Science & Business Media
ISBN 13 : 3540297820
Total Pages : 351 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Plant Metabolomics by : Kazuki Saito

Download or read book Plant Metabolomics written by Kazuki Saito and published by Springer Science & Business Media. This book was released on 2006-06-29 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolomics – which deals with all metabolites of an organism – is a rapidly-emerging sector of post-genome research fields. It plays significant roles in a variety of fields from medicine to agriculture and holds a fundamental position in functional genomics studies and their application in plant biotechnology. This volume comprehensively covers plant metabolomics for the first time. The chapters offer cutting-edge information on analytical technology, bioinformatics and applications. They were all written by leading researchers who have been directly involved in plant metabolomics research throughout the world. Up-to-date information and future developments are described, thereby producing a volume which is a landmark of plant metabolomics research and a beneficial guideline to graduate students and researchers in academia, industry, and technology transfer organizations in all plant science fields.

The New Frontier of Network Physiology: From Temporal Dynamics to the Synchronization and Principles of Integration in Networks of Physiological Systems

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Publisher : Frontiers Media SA
ISBN 13 : 2889714357
Total Pages : 842 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis The New Frontier of Network Physiology: From Temporal Dynamics to the Synchronization and Principles of Integration in Networks of Physiological Systems by : Plamen Ch. Ivanov

Download or read book The New Frontier of Network Physiology: From Temporal Dynamics to the Synchronization and Principles of Integration in Networks of Physiological Systems written by Plamen Ch. Ivanov and published by Frontiers Media SA. This book was released on 2022-02-17 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Progress in Cell Cycle Research

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Publisher : Springer
ISBN 13 : 9781461374510
Total Pages : 0 pages
Book Rating : 4.3/5 (745 download)

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Book Synopsis Progress in Cell Cycle Research by : Laurent Meijer

Download or read book Progress in Cell Cycle Research written by Laurent Meijer and published by Springer. This book was released on 2012-10-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest volume in this highly regarded series covers current advances in the fast-moving field of cell cycle research by gathering reviews otherwise scattered throughout the literature. Contributions encompass fields from cell and molecular biology to biochemistry.

Quantitative Analysis of Ecological Networks

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Publisher : Cambridge University Press
ISBN 13 : 1108632971
Total Pages : 250 pages
Book Rating : 4.1/5 (86 download)

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Book Synopsis Quantitative Analysis of Ecological Networks by : Mark R. T. Dale

Download or read book Quantitative Analysis of Ecological Networks written by Mark R. T. Dale and published by Cambridge University Press. This book was released on 2021-04-15 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Network thinking and network analysis are rapidly expanding features of ecological research. Network analysis of ecological systems include representations and modelling of the interactions in an ecosystem, in which species or factors are joined by pairwise connections. This book provides an overview of ecological network analysis including generating processes, the relationship between structure and dynamic function, and statistics and models for these networks. Starting with a general introduction to the composition of networks and their characteristics, it includes details on such topics as measures of network complexity, applications of spectral graph theory, how best to include indirect species interactions, and multilayer, multiplex and multilevel networks. Graduate students and researchers who want to develop and understand ecological networks in their research will find this volume inspiring and helpful. Detailed guidance to those already working in network ecology but looking for advice is also included.

Network Medicine

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Publisher : Harvard University Press
ISBN 13 : 0674436539
Total Pages : 449 pages
Book Rating : 4.6/5 (744 download)

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Book Synopsis Network Medicine by : Joseph Loscalzo

Download or read book Network Medicine written by Joseph Loscalzo and published by Harvard University Press. This book was released on 2017-02-01 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Big data, genomics, and quantitative approaches to network-based analysis are combining to advance the frontiers of medicine as never before. With contributions from leading experts, Network Medicine introduces this rapidly evolving field of research, which promises to revolutionize the diagnosis and treatment of human diseases.

Necrotizing Soft Tissue Infections

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Publisher : Springer Nature
ISBN 13 : 3030576167
Total Pages : 212 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Necrotizing Soft Tissue Infections by : Anna Norrby-Teglund

Download or read book Necrotizing Soft Tissue Infections written by Anna Norrby-Teglund and published by Springer Nature. This book was released on 2020-10-20 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume aims to enhance the current understanding of clinical features, treatment and pathogenic aspects in necrotizing soft tissue infections. Various representative case studies are discussed to enhance the readers’ understanding of these complex diseases. Necrotizing soft tissue infections are rapidly spreading infections that may cause extensive soft tissue or limb loss, multiorgan failure and are associated with a considerable fatality rate. It is undisputed that rapid diagnosis and prompt intervention is directly related to survival. The initial presentation may be limited to unspecific symptoms such as tenderness, swelling, erythema and pain. Thus, diagnosis and management are challenging due to heterogeneity in clinical presentation, in co-morbidities, in microbiological aetiology, as well as in the pathogenic mechanisms. An international and multidisciplinary consortium, INFECT, has for the last 6 years been pursuing research aimed to advance the understanding of the clinical and pathogenic aspects of these infections. A central part has been to create a comprehensive clinical registry and associated biobank which have also formed the basis for the experimental studies. Using the INFECT patient cohort, as well as an integrated systems biology approach in patients and clinically relevant experimental models, an advanced insight of diagnostic features, causative microbial agents, treatment strategies, and pathogenic mechanisms (host and bacterial disease traits and their underlying interaction network) has been obtained.

Genetics Meets Metabolomics

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Publisher : Springer Science & Business Media
ISBN 13 : 1461416892
Total Pages : 328 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Genetics Meets Metabolomics by : Karsten Suhre

Download or read book Genetics Meets Metabolomics written by Karsten Suhre and published by Springer Science & Business Media. This book was released on 2012-06-15 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is written by leading researchers in the fields about the intersection of genetics and metabolomics which can lead to more comprehensive studies of inborn variation of metabolism.

Issues in Applied, Analytical, and Imaging Sciences Research: 2011 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464964106
Total Pages : 2773 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Issues in Applied, Analytical, and Imaging Sciences Research: 2011 Edition by :

Download or read book Issues in Applied, Analytical, and Imaging Sciences Research: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 2773 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Applied, Analytical, and Imaging Sciences Research: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Applied, Analytical, and Imaging Sciences Research. The editors have built Issues in Applied, Analytical, and Imaging Sciences Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Applied, Analytical, and Imaging Sciences Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Applied, Analytical, and Imaging Sciences Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Soft Computing in Data Science

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Publisher : Springer
ISBN 13 : 9811027773
Total Pages : 311 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Soft Computing in Data Science by : Michael W. Berry

Download or read book Soft Computing in Data Science written by Michael W. Berry and published by Springer. This book was released on 2016-09-17 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the International Conference on Soft Computing in Data Science, SCDS 2016, held in Putrajaya, Malaysia, in September 2016. The 27 revised full papers presented were carefully reviewed and selected from 66 submissions. The papers are organized in topical sections on artificial neural networks; classification, clustering, visualization; fuzzy logic; information and sentiment analytics.