Contemporary Topics in Molecular Immunology

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ISBN 13 : 9781468439182
Total Pages : 244 pages
Book Rating : 4.4/5 (391 download)

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Book Synopsis Contemporary Topics in Molecular Immunology by : F. P. Inman

Download or read book Contemporary Topics in Molecular Immunology written by F. P. Inman and published by . This book was released on 2014-09-01 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Contemporary Topics in Molecular Immunology

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ISBN 13 : 9781468428421
Total Pages : 272 pages
Book Rating : 4.4/5 (284 download)

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Book Synopsis Contemporary Topics in Molecular Immunology by : R. Porter

Download or read book Contemporary Topics in Molecular Immunology written by R. Porter and published by . This book was released on 2014-01-15 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Contemporary Topics in Molecular Immunology

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ISBN 13 : 9781468445183
Total Pages : 264 pages
Book Rating : 4.4/5 (451 download)

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Book Synopsis Contemporary Topics in Molecular Immunology by : F. Inman

Download or read book Contemporary Topics in Molecular Immunology written by F. Inman and published by . This book was released on 2014-01-15 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Contemporary Topics in Molecular Immunology

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Publisher : Springer Science & Business Media
ISBN 13 : 1461589304
Total Pages : 258 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Contemporary Topics in Molecular Immunology by : F. P. Inman

Download or read book Contemporary Topics in Molecular Immunology written by F. P. Inman and published by Springer Science & Business Media. This book was released on 2013-11-22 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are many unanswered questions regarding the molecular nature of antibodies, components of complement, and other substances which participate in the immune response. The list of substances which need to be analyzed chemically is increasing. Plasma cell products, of course, have long been of great interest because the most prevalent ones are immunoglobulins. Other cell types, however, are the source of the broad spectrum of additional substances which classically fall into the sanctum of the molecular immunologist. It is these substances, and especially those more recently discovered, which are responsible for the broadening investigative interests of immunologists. In this volume we have provided you with descriptions of research being done with immunoglobulins and with complement. Additionally, we have in cluded two reports that deal with molecules which are among the more recent acquisitions of the molecular immunologist. The components of complement are known to react in a cascading manner which results in the lysis of cellular antigens. The first step in the classical pathway requires the activation of CI by the antibody-antigen aggregates. This volume of Contemporary Topics in Molecular Immunology begins with the report of Reid and Porter which describes their investigation of the mechanism of activation of C I. Their descriptions of C I q and of the reaction of C I with immunoglobulins are especially intriguing. It is clearly apparent from their report that activation of the components of complement is a complex phenome non.

Contemporary Topics in Molecular Immunology

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ISBN 13 : 9781468477740
Total Pages : 296 pages
Book Rating : 4.4/5 (777 download)

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Book Synopsis Contemporary Topics in Molecular Immunology by : R. Reisfeld

Download or read book Contemporary Topics in Molecular Immunology written by R. Reisfeld and published by . This book was released on 2014-01-15 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Contemporary Topics in Molecular Immunology

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (429 download)

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Book Synopsis Contemporary Topics in Molecular Immunology by :

Download or read book Contemporary Topics in Molecular Immunology written by and published by . This book was released on 1973 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Contemporary Topics in Molecular Immunology

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ISBN 13 : 9781468481433
Total Pages : 256 pages
Book Rating : 4.4/5 (814 download)

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Book Synopsis Contemporary Topics in Molecular Immunology by : H. Eisen

Download or read book Contemporary Topics in Molecular Immunology written by H. Eisen and published by . This book was released on 2014-01-15 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Contemporary Topics in Molecular Immunology

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Publisher : Springer Science & Business Media
ISBN 13 : 1468439170
Total Pages : 238 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Contemporary Topics in Molecular Immunology by : F. P. Inman

Download or read book Contemporary Topics in Molecular Immunology written by F. P. Inman and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Included in this volume is a broad range of topics. Immunology is such a diverse field that many of the subspecialties overlap, and one finds it convenient and necessary to integrate information from several of them. We try to focus on the molecular aspects of immunology as much as is reasonable, but some con tributions consist of ablend of molecular and cellular immunology and even immunopathology. This is as it should be, since information at the molecular level often provides an explanation of phenomena observed at other levels. Myelin basic protein holds the interest of immunologists because it is impli cated in the induction of the autoimmune disease called experimental allergie encephalomyelitis (EAE). Although much biochemical and immunological information about this protein has been uncovered, it is not understood how such an inaccessible self-antigen can serve as the focal point in the central ner vous system for myelin basic protein-specific EAE-inducing T cells. Day dis cusses the problem by first reviewing the sequences of the proteins from several species and the antigenicity of the proteins and peptides derived from them. The reader is then led into a thorough discussion of the immunological relation ships that do and do not influence development of the encephalitis. From this discussion, the author promulgates the bystander model as the best overall mechanism to explain why different fragments of the highly conserved protein are needed by various species to give rise to the same type of localized central nervous system disease.

Contemporary Topics in Molecular Immunology

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ISBN 13 : 9781468428391
Total Pages : 280 pages
Book Rating : 4.4/5 (283 download)

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Book Synopsis Contemporary Topics in Molecular Immunology by : Gordon Ada

Download or read book Contemporary Topics in Molecular Immunology written by Gordon Ada and published by . This book was released on 1974-09-01 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Contemporary Topics in Molecular Immunology

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Publisher : Springer
ISBN 13 : 9781468428407
Total Pages : 260 pages
Book Rating : 4.4/5 (284 download)

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Book Synopsis Contemporary Topics in Molecular Immunology by : Gordon Ada

Download or read book Contemporary Topics in Molecular Immunology written by Gordon Ada and published by Springer. This book was released on 2012-03-19 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: A series of volumes devoted to molecular immunology will contain, for the most part, articles which attempt to explain immunological phenomena in terms of the behavior and properties of particular molecules. Many of the articles in this volume do this. At the same time, there are many instances-and this is particularly so in the case of immunology-where phenomena must first be described and interpreted in terms of the properties and behavior of cells. Most of us would hope that in due course a fuller understanding will be forthcoming. This volume starts off with such a contribution. Perhaps the most fascinat ing problem in immunology is how diversity is generated. There are two broad proposals: (1) that complete information exists ab initio (the germ-line theory), and (2) that there is initially a limited amount of information, and diversity is generated by somatic mutation. The issue is unresolved, but Cunningham has taken many of the data which have previously been used to support the germ-line theory and shows that the interpretations are not always clear-cut and can frequently be used to support another possibility-that new specificities may arise after stimulation of appropriate cells by antigens. And he has produced experimental evidence to support this notion. On the other hand, there can be little doubt that to a considerable degree the specificity of the immune response is determined by the selection by antigen of cells with receptors of appropriate specificity. This is essentially a surface phenomenon.

Contemporary Topics in Molecular Immunology, V. 3

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (914 download)

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Book Synopsis Contemporary Topics in Molecular Immunology, V. 3 by : Ralph A. Reisfeld

Download or read book Contemporary Topics in Molecular Immunology, V. 3 written by Ralph A. Reisfeld and published by . This book was released on 1974 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Contemporary Topics in Molecular Immunology, V.6

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ISBN 13 :
Total Pages : 252 pages
Book Rating : 4.:/5 (98 download)

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Book Synopsis Contemporary Topics in Molecular Immunology, V.6 by : G. L. Ada

Download or read book Contemporary Topics in Molecular Immunology, V.6 written by G. L. Ada and published by . This book was released on 1977 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Contemporary Topics in Molecular Immunology

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Publisher : Springer
ISBN 13 : 9780306361043
Total Pages : 272 pages
Book Rating : 4.3/5 (61 download)

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Book Synopsis Contemporary Topics in Molecular Immunology by : F. P. Inman

Download or read book Contemporary Topics in Molecular Immunology written by F. P. Inman and published by Springer. This book was released on 1975-09-01 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are many unanswered questions regarding the molecular nature of antibodies, components of complement, and other substances which participate in the immune response. The list of substances which need to be analyzed chemically is increasing. Plasma cell products, of course, have long been of great interest because the most prevalent ones are immunoglobulins. Other cell types, however, are the source of the broad spectrum of additional substances which classically fall into the sanctum of the molecular immunologist. It is these substances, and especially those more recently discovered, which are responsible for the broadening investigative interests of immunologists. In this volume we have provided you with descriptions of research being done with immunoglobulins and with complement. Additionally, we have in cluded two reports that deal with molecules which are among the more recent acquisitions of the molecular immunologist. The components of complement are known to react in a cascading manner which results in the lysis of cellular antigens. The first step in the classical pathway requires the activation of CI by the antibody-antigen aggregates. This volume of Contemporary Topics in Molecular Immunology begins with the report of Reid and Porter which describes their investigation of the mechanism of activation of C I. Their descriptions of C I q and of the reaction of C I with immunoglobulins are especially intriguing. It is clearly apparent from their report that activation of the components of complement is a complex phenome non.

Contemporary Topics in Molecular Immunology

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Publisher : Springer Science & Business Media
ISBN 13 : 1468445170
Total Pages : 256 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Contemporary Topics in Molecular Immunology by : F. Inman

Download or read book Contemporary Topics in Molecular Immunology written by F. Inman and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: recipients and acceptance of allografts can be made. The authors have the experi ence and ability to bridge the entire field of transplantation and their article encompasses both clinical and immunochemical data in this area. Their data show clearly that matches for the DR antigens are more important than those at the ABC loci in determination of graft survival. Additional relevant factors, in cluding autoimmunity and other B-cell antigens, are discussed and correlated with graft survival. The authors also present pathology data concerning the distribution of HLA-DR antigens in various tissues. These data indicate a fruitful area for future investigations on the chemical aspects of the various antigens encoded within the human MHC. Do changes in the structure of lymphocyte surface glycoproteins, especially changes in their carbohydrate portions, occur during normal lymphoid differen tiation? Information about this question is limited, and pertinent data are avail able for only a few proteins. Three of the proteins are major glycoprotein con stituents of rodent thymocyte membranes: the Thy-! antigen, a glycosylated leukocyte sialoglycoprotein called W3/13, and a high-molecular-weight glycopro tein known as the leukocyte-common antigen. In his contribution, Pink thor oughly characterizes these glycoproteins and discusses the evidence that the structures change when a thymocyte differentiates into a mature, peripheral T cell. A comparison is drawn between lymphocyte glycoprotein changes and those that occur during red blood cell differentiation. The reader will find Pink's discourse informative and provocative. Mast cells, basophils, and related tumor lines bind IgE with very high affinity.

Contemporary Topics in Immunochemistry

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Publisher : Springer Science & Business Media
ISBN 13 : 1475713436
Total Pages : 196 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Contemporary Topics in Immunochemistry by : F. Inman

Download or read book Contemporary Topics in Immunochemistry written by F. Inman and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1897, Ehrlich suggested that natural preformed receptors from the surface of cells provided immunity to various chemical substances. Many years later, in 1940, Pauling proffered the concept that antibodies comprised a single poly peptide chain and that each end of the protein could form an antigen-binding site. Burnet tried to explain the diversity of antibody specificity by hypothesizing that it was cell-derived. These hypotheses probably have led to as much or more experimentation and discussion than any other of the many conjectures set forth to explain immunity on a molecular and cellular basis. Extensive investigations, initially stimulated by these propositions, proved Pauling's notion incorrect. In its demise, however, the multichain structure of the immunoglobulins was realized. In retrospect it be comes obvious that Ehrlich's idea, though not correct, was borne of amazing logic and cognition. Expansion of Burnet's theory seems to be occurring presently; much excitement is engendered by the finding of cell-bound immunoglobulin receptors. Ouring the preceding dozen years, immunochemists have accumulated enormous quantities of data. Though there is so much yet to be done, as a result of this research one may now discuss antigen-binding sites in relation to the protein's primary structure. There is even considerable understanding of the cellular assembly of some immunoglobulins. Entire books can be written about the chemistry of antigens and of complement.

Contemporary Topics in Immunobiology

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Publisher : Springer Science & Business Media
ISBN 13 : 1468430459
Total Pages : 277 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Contemporary Topics in Immunobiology by : Max Cooper

Download or read book Contemporary Topics in Immunobiology written by Max Cooper and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contemporary immunobiology is an ever-diversifying field that embraces many aspects of cellular and humoral immune responsiveness. This includes the phylogeny, ontogeny, induction, regulation, expression, and differentiation of the immune-cell series, as well as the relationship of these to the pathogenesis of many disease processes. It is clearly beyond the limitations of each volume in this series to comprehensively cover progress in each of these fields. Three general areas of contemporary investigations are discussed in the current issue: cellular events of B cell differentiation, including antigen recognition and respon siveness of B lymphocytes; regulation of the immune response by T cells, and the roles of this regulatory system in allotype suppression and in autoimm unity; and the genetic control of immune responses and its possible relation to disease pathogenesis. Analysis of responsiveness of B lymphocytes has been greatly aided by the availability of athymic nude mice. The immunological responsiveness of these mice to a wide range of stimuli has been reviewed and analyzed by H. H. Wortis. This article concludes with the provocative thesis that in the future "nudes will supply new rather than confirmatory data . . . (especially regarding) the develop ment of neoplasia. " In contrast to the studies on the congenitally athymic mice, G. F.

Contemporary Topics in Immunobiology, Vol. 7:T Cells

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Publisher : Springer Science & Business Media
ISBN 13 : 1468430548
Total Pages : 397 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Contemporary Topics in Immunobiology, Vol. 7:T Cells by : Osis Stutman

Download or read book Contemporary Topics in Immunobiology, Vol. 7:T Cells written by Osis Stutman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: And even I can remember A day when historians left blanks in their writings, I mean for things they didn't know. -Ezra Pound, Canto XIII * The prefaces to the previous volumes of this series have all expressed in various ways the actual motivation behind these collective efforts. There was agreement in most instances that we are facing some kind of publication explosion, and that the present type of compact and personalized reviews may be of help, from both a conceptual and a purely informational standpoint. The aims of the series were, and still are, to focus attention on the rapidly changing fields within the realm of immunology, and to present in each chapter the summation of results generated by an investigator or group of Investigators, either as an analysis of their own work or as a correlation of such work with the general field in question. The present volume does not differ in its construction from its predecessors, although it does concentrate on a single target, the T lymphocyte and its biology. The selection of subjects as well as contributors has been the sole responsi bility of this editor; however, the actual format and length of the individual contributions was left to the discretion and inspiration of the different authors. Even the styles, ranging from the concise statement to the meticulously detailed review, attest to the freedom of format.