Construction And Characterization Of Human Adenovirus Recombinants Expressing The Vesicular Stomatitis Virus Glycoprotein Gene

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Adenoviral Vectors for Gene Therapy

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Author : David T. Curiel
Publisher : Academic Press
ISBN 13 : 0128005106
Total Pages : 870 pages
Book Rating : 4.1/5 (28 download)

Book Synopsis Adenoviral Vectors for Gene Therapy by : David T. Curiel

Download or read book Adenoviral Vectors for Gene Therapy written by David T. Curiel and published by Academic Press. This book was released on 2016-03-10 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research. This book presents topics ranging from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models, with final consideration of the regulatory issues surrounding human clinical gene therapy trials. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors. - Provides complete coverage of the basic biology of adenoviruses, as well as their construction, propagation, and purification of adenoviral vectors - Introduces common strategies for the development of adenoviral vectors, along with cutting-edge methods for their improvement - Demonstrates noninvasive imaging of adenovirus-mediated gene transfer - Discusses utility of adenoviral vectors in animal disease models - Considers Federal Drug Administration regulations for human clinical trials

Viral Vectors

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Author : Michael G. Kaplitt
Publisher : Academic Press
ISBN 13 : 008054357X
Total Pages : 525 pages
Book Rating : 4.0/5 (85 download)

Book Synopsis Viral Vectors by : Michael G. Kaplitt

Download or read book Viral Vectors written by Michael G. Kaplitt and published by Academic Press. This book was released on 1995-08-14 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic manipulation of the adult mammalian nervous system is one of the most exciting areas in contemporary neurobiology. The explosive growth of this field has been facilitated by harnessing the power of viruses to transfer genetic material into mammalian cells.Viral Vectors: Gene Therapy and Neuroscience Applications represents the first comprehensive review of viral vector applications to the nervous system by leaders in virology, molecular neurobiology, neuroanatomy, and developmental neurobiology. It serves both as a source of fundamental information for those newly interested in viral vectors and as a compilation of state-of-the-art technologies and applications for more experienced researchers.This work provides expert background information on viral systems, and the broad range of applications will help readers appreciate the current and future impact of viral vectors in both clinical and basic neuroscience.

Ebola and Marburg Viruses

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Author : Hans-Dieter Klenk
Publisher : Garland Science
ISBN 13 : 9780954523237
Total Pages : 392 pages
Book Rating : 4.5/5 (232 download)

Book Synopsis Ebola and Marburg Viruses by : Hans-Dieter Klenk

Download or read book Ebola and Marburg Viruses written by Hans-Dieter Klenk and published by Garland Science. This book was released on 2004 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Ebola and Marburg viruses are a pair of filoviruses that are among the most lethal hemorrhagic viruses on the planet. The authors present a review of past and current research into these pathogens, including 12 papers addressing the structure of the viral proteins; genomic replication; molecular mechanisms of entry; pathogenesis in nonhuman primates, guinea pigs, and mice; virus modulation of innate immunity; and cellular and molecular mechanisms of Ebola pathogenicity and related approaches to vaccine development.

Cumulated Index Medicus

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Author :
Publisher :
ISBN 13 :
Total Pages : 1860 pages
Book Rating : 4.:/5 (319 download)

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Download or read book Cumulated Index Medicus written by and published by . This book was released on 1997 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Baculovirus Expression Vectors

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Author : David R. O'Reilly
Publisher :
ISBN 13 : 9780195091311
Total Pages : 366 pages
Book Rating : 4.0/5 (913 download)

Book Synopsis Baculovirus Expression Vectors by : David R. O'Reilly

Download or read book Baculovirus Expression Vectors written by David R. O'Reilly and published by . This book was released on 1994 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Baculoviruses have proven to be the most powerful and versatile eukaryotic expression vectors available. This unique laboratory manual is designed to help both beginning and experienced researchers construct and use baculovirus vector systems. It simplifies selection of the most appropriatebaculovirus vector design for a given problem, then describes each step of the implementation process--from vector construction to large-scale protein production. The book provides an understanding of how the vectors work; a biological overview of cells, viruses, plasmids, and promoters; guidelinesfor choosing optimum vectors; protocols for growing insect cells and recombinant viruses; methods of analyzing protein products and scaling up protein production; techniques for producing proteins in insect larvae; and easy-to-use maps charting available expression vectors. This comprehensiveapproach has many benefits for researchers and students alike. It allows them to understand how and why the vector system works and offers a rapid comparison of options for choosing the right virus, plasmid or promoter for vector design and construction, with a minimum amount of lost time. Themanual is an invaluable resource for every individual engaged in the production of proteins for any purpose.

Oncoimmunology

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Author : Laurence Zitvogel
Publisher : Springer
ISBN 13 : 3319624318
Total Pages : 700 pages
Book Rating : 4.3/5 (196 download)

Book Synopsis Oncoimmunology by : Laurence Zitvogel

Download or read book Oncoimmunology written by Laurence Zitvogel and published by Springer. This book was released on 2017-12-13 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, leading experts in cancer immunotherapy join forces to provide a comprehensive guide that sets out the main principles of oncoimmunology and examines the latest advances and their implications for clinical practice, focusing in particular on drugs with FDA/EMA approvals and breakthrough status. The aim is to deliver a landmark educational tool that will serve as the definitive reference for MD and PhD students while also meeting the needs of established researchers and healthcare professionals. Immunotherapy-based approaches are now inducing long-lasting clinical responses across multiple histological types of neoplasia, in previously difficult-to-treat metastatic cancers. The future challenges for oncologists are to understand and exploit the cellular and molecular components of complex immune networks, to optimize combinatorial regimens, to avoid immune-related side effects, and to plan immunomonitoring studies for biomarker discovery. The editors hope that this book will guide future and established health professionals toward the effective application of cancer immunology and immunotherapy and contribute significantly to further progress in the field.

Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases E-Book

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Author : John E. Bennett
Publisher : Elsevier Health Sciences
ISBN 13 : 1437720609
Total Pages : 4306 pages
Book Rating : 4.4/5 (377 download)

Book Synopsis Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases E-Book by : John E. Bennett

Download or read book Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases E-Book written by John E. Bennett and published by Elsevier Health Sciences. This book was released on 2009-10-19 with total page 4306 pages. Available in PDF, EPUB and Kindle. Book excerpt: After thirty years, PPID is still the reference of choice for comprehensive, global guidance on diagnosing and treating the most challenging infectious diseases. Drs. Mandell, Bennett, and Dolin have substantially revised and meticulously updated, this new edition to save you time and to ensure you have the latest clinical and scientific knowledge at your fingertips. With new chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 7th Edition helps you identify and treat whatever infectious disease you see. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Get the answers to questions you have with more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than you’ll find in any other infectious disease resource. Find the latest diagnoses and treatments for currently recognized and newly emerging infectious diseases, such as those caused by avian and swine influenza viruses. Put the latest knowledge to work in your practice with new or completely revised chapters on influenza (new pandemic strains); new Middle East respiratory syndrome (MERS) virus; probiotics; antibiotics for resistant bacteria; antifungal drugs; new antivirals for hepatitis B and C; Clostridium difficile treatment; sepsis; advances in HIV prevention and treatment; viral gastroenteritis; Lyme disease; Helicobacter pylori; malaria; infections in immunocompromised hosts; immunization (new vaccines and new recommendations); and microbiome. Benefit from fresh perspectives and global insights from an expanded team of international contributors. Find and grasp the information you need easily and rapidly with newly added chapter summaries. These bulleted templates include diagnosis, therapy, and prevention and are designed as a quick summary of the chapter and to enhance relevancy in search and retrieval on Expert Consult. Stay current on Expert Consult with a thorough and regularly scheduled update program that ensures access to new developments in the field, advances in therapy, and timely information. Access the information you need easily and rapidly with new succinct chapter summaries that include diagnosis, therapy, and prevention. Experience clinical scenarios with vivid clarity through a richly illustrated, full-color format that includes 1500 photographs for enhanced visual guidance.

Fields' Virology

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Author : David Mahan Knipe
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781760607
Total Pages : 3116 pages
Book Rating : 4.7/5 (66 download)

Book Synopsis Fields' Virology by : David Mahan Knipe

Download or read book Fields' Virology written by David Mahan Knipe and published by Lippincott Williams & Wilkins. This book was released on 2007 with total page 3116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Accompanying CD-ROM has same title as book.

Index Medicus

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Author :
Publisher :
ISBN 13 :
Total Pages : 1940 pages
Book Rating : 4.:/5 (319 download)

Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 1940 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Research Awards Index

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Author :
Publisher :
ISBN 13 :
Total Pages : 1170 pages
Book Rating : 4.3/5 ( download)

Book Synopsis Research Awards Index by :

Download or read book Research Awards Index written by and published by . This book was released on 1982 with total page 1170 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Recombinant DNA Research and Viruses

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Author : Yechiel Becker
Publisher : Springer Science & Business Media
ISBN 13 : 146132565X
Total Pages : 372 pages
Book Rating : 4.4/5 (613 download)

Book Synopsis Recombinant DNA Research and Viruses by : Yechiel Becker

Download or read book Recombinant DNA Research and Viruses written by Yechiel Becker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of recombinant DNA technology has made a marked impact on molecular virology. The cleavage of viral DNA genomes with restriction enzymes and the cloning of such DNA fragments in bacterial p1asmids has led to the amplification of selected viral DNA fragments for sequencing and gene expression. RNA virus genomes which can be transcribed to their cDNA form were also cloned in bacterial p1asmids, facilitating the study of RNA virus genes. With the elucidation in recent years of the promoter sequence of various viral genes and the expression of these genes in bacteria or yeast, the understanding of many viral gene functions has made great progress. Cloning and expression of viral genes in mammalian cells was made possible by the construction of shuttle plasmid vectors which carry the origins of DNA replication from bacteria and/or mammalian viruses. The expression of viral genes in bacteria, yeast and eukaryotic cells gives reason to hope that it will be possible to produce viral antigens in large quantities for use as human or animal vaccines. The present volume attempts to capture for the reader some of the high lights of recombinant DNA research in the field of animal and plant viruses.

Virology & AIDS Abstracts

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Author :
Publisher :
ISBN 13 :
Total Pages : 854 pages
Book Rating : 4.0/5 ( download)

Book Synopsis Virology & AIDS Abstracts by :

Download or read book Virology & AIDS Abstracts written by and published by . This book was released on 1991 with total page 854 pages. Available in PDF, EPUB and Kindle. Book excerpt: Monthly. Includes references to literature on phage, animal, or plant viruses, as well as molecular, in vitro, immunological, clinical, epidemiological and other aspects of AIDS. Topical arrangement. Author, subject indexes.

Mammalian Cell Biotechnology in Protein Production

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Author : Hansjörg Hauser
Publisher : Walter de Gruyter
ISBN 13 : 3110809281
Total Pages : 513 pages
Book Rating : 4.1/5 (18 download)

Book Synopsis Mammalian Cell Biotechnology in Protein Production by : Hansjörg Hauser

Download or read book Mammalian Cell Biotechnology in Protein Production written by Hansjörg Hauser and published by Walter de Gruyter. This book was released on 2011-07-13 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: „Hauser und Wagner haben die neuen Möglichkeiten der Mammalian Cell Biology sehr anregend dargestellt.“ Prof. Dr. Hans Fritz, Ludwig-Maximilians-Universität München

Abeloff's Clinical Oncology E-Book

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Author : John E. Niederhuber
Publisher : Elsevier Health Sciences
ISBN 13 : 1455728810
Total Pages : 2712 pages
Book Rating : 4.4/5 (557 download)

Book Synopsis Abeloff's Clinical Oncology E-Book by : John E. Niederhuber

Download or read book Abeloff's Clinical Oncology E-Book written by John E. Niederhuber and published by Elsevier Health Sciences. This book was released on 2013-09-12 with total page 2712 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical and clinically focused, Abeloff’s Clinical Oncology is a trusted medical reference book designed to capture the latest scientific discoveries and their implications for cancer diagnosis and management of cancer in the most accessible manner possible. Abeloff’s equips everyone involved - from radiologists and oncologists to surgeons and nurses - to collaborate effectively and provide the best possible cancer care. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Select the most appropriate tests and imaging studies for cancer diagnosis and staging of each type of cancer, and manage your patients in the most effective way possible by using all of the latest techniques and approaches in oncology. Enhance your understanding of complex concepts with a color art program that highlights key points and illustrates relevant scientific and clinical problems. Stay at the forefront of the latest developments in cancer pharmacology, oncology and healthcare policy, survivorship in cancer, and many other timely topics. See how the most recent cancer research applies to practice through an increased emphasis on the relevance of new scientific discoveries and modalities within disease chapters. Streamline clinical decision making with abundant new treatment and diagnostic algorithms as well as concrete management recommendations. Take advantage of the collective wisdom of preeminent multidisciplinary experts in the field of oncology, including previous Abeloff’s editors John E. Niederhuber, James O. Armitage, and Michael B. Kastan as well as new editors James H. Doroshow from the National Cancer Institute and Joel E. Tepper of Gunderson & Tepper: Clinical Radiation Oncology. Quickly and effortlessly access the key information you need with the help of an even more user-friendly, streamlined format. Access the complete contents anytime, anywhere at Expert Consult, and test your mastery of the latest knowledge with 500 online multiple-choice review questions.

Principles of Tissue Engineering

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Author : Robert Lanza
Publisher : Academic Press
ISBN 13 : 0080548849
Total Pages : 1344 pages
Book Rating : 4.0/5 (85 download)

Book Synopsis Principles of Tissue Engineering by : Robert Lanza

Download or read book Principles of Tissue Engineering written by Robert Lanza and published by Academic Press. This book was released on 2011-10-13 with total page 1344 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1997, Principles of Tissue Engineering is the widely recognized definitive resource in the field. The third edition provides a much needed update of the rapid progress that has been achieved in the field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world's experts of what is currently known about each specific organ system. This edition includes greatly expanded focus on stem cells, including adult and embryonic stem cells and progenitor populations that may soon lead to new tissue engineering therapies for heart disease, diabetes, and a wide variety of other diseases that afflict humanity. This up-to-date coverage of stem cell biology and other emerging technologies is complemented by a series of new chapters on recent clinical experience in applying tissue engineering. The result is a comprehensive textbook that we believe will be useful to students and experts alike.New to this edition:*Includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves*Expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems

Hepatobiliary and Pancreatic Cancer

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Author : Daniele Regge
Publisher : Springer
ISBN 13 : 3319502964
Total Pages : 127 pages
Book Rating : 4.3/5 (195 download)

Book Synopsis Hepatobiliary and Pancreatic Cancer by : Daniele Regge

Download or read book Hepatobiliary and Pancreatic Cancer written by Daniele Regge and published by Springer. This book was released on 2018-02-26 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the pathways of dissemination of primary liver, biliary, and pancreatic neoplasms and proposes a practical and clinically driven approach to their imaging. The typical dissemination pathways for hepatocellular carcinoma, cholangiocarcinoma, exocrine pancreatic carcinoma, and neuroendocrine pancreatic tumors are systematically reviewed, and more unusual pathways are also documented. The content is presented in an extremely schematic way, with numerous high-quality graphical illustrations and multimodality images (US, CT, MRI, and PET) that are accompanied by clear explanatory text. The clinical significance of findings and potential therapeutic options are explained whenever appropriate. In addition, relevant background information is provided on the role of morphopathological drivers of cancer spread and anatomy.

Biotechnology Research Abstracts

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Author :
Publisher :
ISBN 13 :
Total Pages : 954 pages
Book Rating : 4.:/5 ( download)

Book Synopsis Biotechnology Research Abstracts by :

Download or read book Biotechnology Research Abstracts written by and published by . This book was released on 1989 with total page 954 pages. Available in PDF, EPUB and Kindle. Book excerpt: Monthly. Classified listing of references to worldwide articles dealing with all aspects of biotechnology. Also includes books and conferences. Each entry gives bibliographic information, institutional address of author(s), and abstract. Author and subject index.