Concomitant Continuous Infusion Chemotherapy and Radiation

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Publisher : Springer Science & Business Media
ISBN 13 : 3642841864
Total Pages : 290 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Concomitant Continuous Infusion Chemotherapy and Radiation by : Marvin Rotman

Download or read book Concomitant Continuous Infusion Chemotherapy and Radiation written by Marvin Rotman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: The administration of chemotherapeutic agents by continuous infusion with concomitant radiation therapy heralds a new approach in the treatment of cancer. This comprehensive book on the subject includes, besides a discussion of its scientific basis, the most promising clinical data on the use of continuous infusion chemotherapy and radiation. Thus, it is an important update for clinical investigators involved in frontline research as well as for practicing physicians participating in the direct care of cancer patients. The contributions include the latest results of this new approach in a number of tumor sites. There is a detailed description of the principles of radiosensitization for malignant tumors and radioprotection for normal tissues; these are the principles which have led to concrete clinical applications. There is also a presentation of the most recent data on the beneficial effects resulting from the administration of commonly used drugs, such as 5-fluorouracil, cisplatinum and adriamycin, with concomitant radiation therapy. Much of the data has never before been published. The wealth of information in this volume makes it a valuable reference; at the same time it gives practicing physicians a detailed presentation of various therapeutic regimens which they could administer in their daily clinical practice. In the future, this innovative cancer treatment may lead to the decreased need for radical surgery and the increased ability to preserve organ function.

Clinical Applications of Continuous Infusion Chemotherapy and Concomitant Radiation Therapy

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461321972
Total Pages : 241 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Clinical Applications of Continuous Infusion Chemotherapy and Concomitant Radiation Therapy by : C. Julian Rosenthal

Download or read book Clinical Applications of Continuous Infusion Chemotherapy and Concomitant Radiation Therapy written by C. Julian Rosenthal and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first conference on concomitant infusion chemotherapy and radia tion therapy was organized with the intention of bringing together some of the investigators who have tested, during the last few years, the hypo thesis that continuous infusion chemotherapy could modulate the cytotoxic effect of radiation therapy to the point of having a strongly additive, if not synergistic activity on certain malignant tumors. This volume represents the detailed proceedings of this conference presented in a way that offers the reader a review of the on-going re search in the field. We have stressed a number of subjects from basic biologic research and influence of cell kinetics to the practical methods of drug delivery systems and early clinical experiences. The rationale for this new type of combined modality therapy has been presented by some of its pioneers. Early clinical investigations as well as the preliminary data of many that have not yet completely matured have also been included. The reader should look at these data with some reser vations. Ultimately, these results must be confirmed by larger prospective randomized studies with proper controls before becoming accepted as the treatment of choice in locally advanced tumors.

Holland-Frei Cancer Medicine

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Publisher : John Wiley & Sons
ISBN 13 : 111900084X
Total Pages : 2008 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.

Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2008 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Rectal Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 8847003431
Total Pages : 250 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Rectal Cancer by : Gian Gaetano Delaini

Download or read book Rectal Cancer written by Gian Gaetano Delaini and published by Springer Science & Business Media. This book was released on 2006-01-26 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite lifestyle improvements, the incidence of rectal cancer is increasing in industrialised countries. Rapid advances in technology, growing knowledge of the biological history of the disease and closer attention to patients' quality of life after surgery have led to a less invasive approach. In the last 15 years, the surgical approach has shifted from extended resection to sphincter-saving procedures, featuring a multidisciplinary approach and a high level of specialisation. The experienced surgeon can plan and choose the "right treatment for the right patient" only with the support of the radiologist, endoscopist and pathologist (preoperative staging), oncologist and radiotherapist (neoadjuvant therapy), and psychologist and stomatherapist (rehabilitation). In addition, the difficult problems of salvage procedure and the reconstruction of anal sphincter after abdominal resection are explored. The aim of this book is to clarify the rapid advances and to offer guidelines for doctors dealing with rectal cancer. Taking into account indications, contraindications, risks, benefits and controversies, the authors offer clear and practice-oriented answers for a wide range of specialists and experts, as well as those new to the field.

Late Sequelae in Oncology

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Publisher : Springer Science & Business Media
ISBN 13 : 3642467946
Total Pages : 436 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Late Sequelae in Oncology by : Jürgen Dunst

Download or read book Late Sequelae in Oncology written by Jürgen Dunst and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing survival figures and the use of more intense combined treatment regimens in modern oncology have raised the problem of late therapeutic sequelae in long-term survivors after cancer. Recent scientific approaches to late sequelae concentrate on the evaluation of subclinical changes with sophisticated functional measurements and experimental investigation of the underlying pathophysiological mechanisms. The objective of the book is to bring together these recent clinical and experimental data from different medical disciplines to give an overview of the most relevant problems of late sequelae. In clinical practice the book may help regarding estimation of risks, selection of diagnostic methods, and estimation of the prognosis of late sequelae.

Handbook on Hyperbaric Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 1402044488
Total Pages : 797 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Handbook on Hyperbaric Medicine by : Daniel Mathieu

Download or read book Handbook on Hyperbaric Medicine written by Daniel Mathieu and published by Springer Science & Business Media. This book was released on 2006-08-18 with total page 797 pages. Available in PDF, EPUB and Kindle. Book excerpt: The decade since the first Handbook on Hyperbaric Medicine has seen major advances: studies have clarified the actions of hyperbaric oxygenation; clinical practice is becoming more scientific; various organisational and operational guidelines are now widely accepted. This new Handbook arises from the EU Co-operation in Science and Technology (COST) programme for hyperbaric medicine, COST B14, in combination with the results of a number of recent experimental and clinical studies.

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1850 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1997 with total page 1850 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Principles of Cancer Biotherapy

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Publisher : Springer Science & Business Media
ISBN 13 : 9400900295
Total Pages : 512 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Principles of Cancer Biotherapy by : R.K. Oldham

Download or read book Principles of Cancer Biotherapy written by R.K. Oldham and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: At the time of the first edition of Principles of Cancer Biotherapy, this book represented the first comprehensive textbook on biological therapy. Whereas in 1991, when the second edition was published, there was still some doubt on the part of many oncologists and cancer researchers as to the therapeutic value of these new approaches, it is now generally agreed that biopharmaceuticals are producing major opportunities for new cancer therapies. Cancer biotherapy has truly matured into the fourth modality of cancer treatment. The third edition is now needed as a result of the tremendous progress that has been made in recent years using biologicals in cancer treatment. The book summarizes an evolving science and a rapidly changing medical practice. As we near the millennium, it now becomes possible to envision a much more diversified system of cancer research and treatment that will afford greater opportunities for patients. Some forms of cancer biotherapy use the strategy of tumour stabilization and control through continued biological therapy, akin to the use of insulin in the treatment of diabetes. This textbook illustrates new methods of thinking and new strategies for control of cancer. It is always difficult to move from past dogma to future opportunity, but this third edition of Principles of Cancer Biotherapy illustrates why it is so important to the patients, for researchers and clinicians to explore and apply these new opportunities in cancer biotherapy.

Radiation Therapy of Benign Diseases

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540005759
Total Pages : 280 pages
Book Rating : 4.0/5 (57 download)

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Book Synopsis Radiation Therapy of Benign Diseases by : Stanley E. Order

Download or read book Radiation Therapy of Benign Diseases written by Stanley E. Order and published by Springer Science & Business Media. This book was released on 2003-04-09 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This expanded and updated second edition is a practical text to aid radiation oncologists in evaluating and treating benign diseases. An introductory chapter by an eminent malpractice lawyer clarifies the medical-legal implications of the radiation treatment of such diseases, and this is followed by the various benign conditions in alphabetical order. In each case, a brief summary is followed by citations of pertinent literature in both explanatory tables and reference lists. Although a comprehensive review, it remains readily comprehensible and will be recognised as the standard text on the subject.

Clinical Target Volumes in Conformal and Intensity Modulated Radiation Therapy

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3662062704
Total Pages : 253 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Clinical Target Volumes in Conformal and Intensity Modulated Radiation Therapy by : Vincent Gregoire

Download or read book Clinical Target Volumes in Conformal and Intensity Modulated Radiation Therapy written by Vincent Gregoire and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conformal radiation therapy represents a new challenge. It offers the prospect of either increasing the radiation dose to target tissues while delivering a similar dose to organs at risk, or reducing the dose to organs at risk while maintaining the dose to target tissues. First, lymph node areas at risk are established using the available data from pathological examination. Then, based on a three-dimensional description of the anatomical regions, guidelines for the delineation of the clinical target volumes are proposed. The data presented should enable the reader to make appropriate decisions regarding the selection and delineation of the target volumes when confronted with the most frequent tumor types and sites.

Cancer Treatment An Update

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Publisher : Springer Science & Business Media
ISBN 13 : 2817807650
Total Pages : 905 pages
Book Rating : 4.8/5 (178 download)

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Book Synopsis Cancer Treatment An Update by : P. Banzet

Download or read book Cancer Treatment An Update written by P. Banzet and published by Springer Science & Business Media. This book was released on 2013-12-14 with total page 905 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers the educational lectures and the texts of the main presenta tions given at the 4th International Congress on Anticancer Chemotherapy which took place in February 1993 in Paris and was attended by 5 000 oncologists from all continents, physicians, students and nurses. This book aspires to give update of the most scientific and clinical aspects of modern oncology. It aims also at showing the prospects that are opened by the rapid progress of cancer biology. The editors are grateful to the authors whose scholarship de fines the quality of the book. Educational lectures The pathogenesis of human cancer metastasis I] Fidler Cancer is a collection of malignancies with each cancer of each organ consist ing of numerous subsets. This biologic and clinical heterogeneity is probably due to the different etiologies, origins, and selection pressures. Despite this heterogeneity, all malignant neoplasms have a uniform characteristic : the ability to invade host tissues and produce metastases. Clinical observations of cancer patients and studies with experimental rodent tumors have revealed that cer tain tumors produce metastasis to specific organs independent of vascular anat omy, rate of blood flow, and number of tumor cells delivered to each organ. The distribution and fate of hematogeneously disseminated, radiolabelled tumor cells in experimental rodent systems amply demonstrate that tumor cells reach the microvasculature of many organs.

Thermoradiotherapy and Thermochemotherapy

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Publisher : Springer Science & Business Media
ISBN 13 : 3642609384
Total Pages : 415 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Thermoradiotherapy and Thermochemotherapy by : M.Heinrich Seegenschmiedt

Download or read book Thermoradiotherapy and Thermochemotherapy written by M.Heinrich Seegenschmiedt and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hyperthermia has been found to be of great benefit in combination with radiation therapy or chemotherapy in the management of patients with difficult and com plicated tumor problems. It has been demonstrated to increase the efficacy of ionizing radiation when used locally but also has been of help in combination with systemic chemotherapy where hyperthermia is carried out to the total body. Triple modality (thermo-chemo-radiotherapy) or other treatment combinations have not been fully evaluated and may demonstrate extended clinical applications in the future. Problems remain with regard to maximizing the effects of hyperthermia as they are influenced by a variety of external and intrinsic factors including bloodflow, microenvironment etc. While the previous volume has summarized more theoretical aspects of hyper thermia, i.e. biology, physiology and physics, the present volume compiles the current knowledge relative to the clinical applications of hyperthermia in combina tion with radiation therapy and/or chemotherapy, providing a comprehensive over view of its use in cancer management.

Modification of Radiation Response

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540422310
Total Pages : 308 pages
Book Rating : 4.4/5 (223 download)

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Book Synopsis Modification of Radiation Response by : Carsten Nieder

Download or read book Modification of Radiation Response written by Carsten Nieder and published by Springer Science & Business Media. This book was released on 2003 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes and summarizes the radiation responses of both normal and neoplastic tissues with a focus on rational strategies for the modification of these responses. Emerging data from molecular oncology and radiobiology are reviewed in depth. The book covers not only general principles of radiation-induced reactions but also a large number of preclinical and clinical data that will guide the reader through this complex and dynamic field and will provide valuable information for the development of further research projects.

Atlas of Endoanal and Endorectal Ultrasonography

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Publisher : Springer Science & Business Media
ISBN 13 : 8847021294
Total Pages : 320 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Atlas of Endoanal and Endorectal Ultrasonography by : Giulio A. Santoro

Download or read book Atlas of Endoanal and Endorectal Ultrasonography written by Giulio A. Santoro and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts

Functional Preservation and Quality of Life in Head and Neck Radiotherapy

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Publisher : Springer Science & Business Media
ISBN 13 : 3540732322
Total Pages : 323 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Functional Preservation and Quality of Life in Head and Neck Radiotherapy by : Paul M. Harari

Download or read book Functional Preservation and Quality of Life in Head and Neck Radiotherapy written by Paul M. Harari and published by Springer Science & Business Media. This book was released on 2009-06-12 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emphasis on cancer management in the past was based primarily on control rates from multidisciplinary input in management. There has always been a recognition that one would like to achieve the best result with the least complication, but never has there been any major emphasis on evidence-based outcome studies, nor on functional preservation and quality of life. The authors of this book have dealt very effectively with the various tumor types in head and neck cancer with the experts in the ? eld of management. The contents range from epidemiology and treatment outcome, treatment techniques with the potential impact on the quality of life such as dysphagia, to the various options relative to high technology radiation therapy programs for mana- ment. The potential for improving form and function through surgical care as an integrated part of the program is dealt with very effectively as well as the potentials for chemotherapy and the use of targeted agents have on quality of life issues. The volume also addresses toxicity, quality of life, and techniques for prevention of adverse effects, as well as the potentials for rehabilitation and supportive care. The authors have clearly done an extraordinarily good job in addressing the mul- plicity of problems that impact upon the functional preservation and quality of life in head and neck radiation therapy. Philadelphia Luther W.

Radiotherapy of Intraocular and Orbital Tumors

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Publisher : Springer Science & Business Media
ISBN 13 : 3642559107
Total Pages : 334 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Radiotherapy of Intraocular and Orbital Tumors by : R.H. Sagerman

Download or read book Radiotherapy of Intraocular and Orbital Tumors written by R.H. Sagerman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition of Radiotherapy of Intraocular and Orbital Tumors in 1993 the treatment programs for cure have changed from the dominance of surgical resection to the utilization of radiation therapy with preservation of the eye intact and preservation of vision. In 2002 about 2,300 primary eye tumors will be diagnosed in the United states, 75% of which will be choroidal melanomas, 20% retinoblastomas, and the remainder a wide variety of tumors - malignant lymphoma, rhabdomyosarcomas, liposarcomas, meningiomas, malignant fibrous histiocytomas, etc. Even so, the majority of malignant tumors of the eye are metastatic, primarily from cancers of the lung or breast. The impact of newer imaging studies, including computed tomography, magnetic resonance imaging, and ultrasound with and without contrast medium, have allowed for better tumor definition, more precise treatment techniques, and major improvement in local control, with preservation of the eye intact and excellent survival. The better histologic definition of the tumor has selected more appropriately the cases suitable for adjuvant chemotherapy particularly demonstrated by the combined integrated multimodal treatment of rhabdomyosarcoma without enucleation. Surgical techniques are now being reserved for biopsy and for treatment failures, a dramatic change in treatment approaches since 1993. The second edition by Sagerman and Alberti clearly demonstrates this major change in treatment. The volume explores the impact of diagnostic workup, the role of surgery, the role of external beam radiation therapy, the use of radioactive plaques, photocoagulation, cryotherapy, and other less major surgical procedures.

Nasopharyngeal Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 3540928103
Total Pages : 336 pages
Book Rating : 4.5/5 (49 download)

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Book Synopsis Nasopharyngeal Cancer by : Jiade J. Lu

Download or read book Nasopharyngeal Cancer written by Jiade J. Lu and published by Springer Science & Business Media. This book was released on 2010-01-13 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nasopharyngeal Cancer - Multidisciplinary Management provides a comprehensive account of the current state of knowledge on nasopharyngeal cancer and its multidisciplinary management. The first ten chapters document contain essential background information on subjects such as epidemiology, pathogenesis, molecular biology, pathology, and the use of imaging in diagnosis and staging. Subsequently, the various treatment options and combinations in a range of settings are examined in depth. Detailed attention is given to the roles of concurrent, adjuvant, and neoadjuvant chemotherapy and advanced radiotherapy techniques. Further chapters then explore surgical treatment, follow-up, treatment of metastatic disease, treatment-related complications, and nasopharyngeal cancer in children. This is an important book that will prove essential reading for the radiation oncology community worldwide and meet the need for substantial improvements in knowledge of modern techniques.