Computer Analysis Of Genetic Macromolecules Structure Function And Evolution

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Computer Analysis of Genetic Macromolecules

Author : N. A. Kolchanov
Publisher : World Scientific
ISBN 13 : 9789810213787
Total Pages : 590 pages
Book Rating : 4.2/5 (137 download)

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Book Synopsis Computer Analysis of Genetic Macromolecules by : N. A. Kolchanov

Download or read book Computer Analysis of Genetic Macromolecules written by N. A. Kolchanov and published by World Scientific. This book was released on 1994 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular biology and genetics are fast-growing fields with significant results and findings being reported virtually every day. Raw data from the wet lab accumulate at an astonishing rate, making it necessary to analyze the biological data with the use of computers. This book reveals how the current challenges of molecular biology and genetics are met with computer and mathematical treatments. A combined effort of the Computational Genetics and Biophysics Group (Supercomputer Computations Research Institute, USA), the Theoretical Molecular Genetics (Russian Academy of Sciences, Russia) and the Bioinformatics Group (Consiglio Nazionale delle Ricerche, Italy), many of these findings are firsthand discoveries made by these groups. The book emphasizes the fundamental principles of the structural-functional organization of the 3 major classes of genetic macromolecules: DNA, RNA and proteins. It also introduces universally applicable theoretical principles into the enormous realm of raw data and develops an integrative, theoretical computer approach to the analysis of these macromolecules to gain insights into the complexities of their function and evolution.

Computer Analysis of Genetic Macromolecules: Structure, Function and Evolution

Author : N A Kolchanov
Publisher : World Scientific
ISBN 13 : 9814504270
Total Pages : 580 pages
Book Rating : 4.8/5 (145 download)

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Book Synopsis Computer Analysis of Genetic Macromolecules: Structure, Function and Evolution by : N A Kolchanov

Download or read book Computer Analysis of Genetic Macromolecules: Structure, Function and Evolution written by N A Kolchanov and published by World Scientific. This book was released on 1994-03-29 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular biology and genetics are fast-growing fields with significant results and findings being reported virtually every day. Raw data from the wet lab accumulate at an astonishing rate, making it necessary to analyze the biological data with the use of computers. This book reveals how the current challenges of molecular biology and genetics are met with computer and mathematical treatments. A combined effort of the Computational Genetics and Biophysics Group (Supercomputer Computations Research Institute, USA), the Theoretical Molecular Genetics (Russian Academy of Sciences, Russia) and the Bioinformatics Group (Consiglio Nazionale delle Ricerche, Italy), many of these findings are firsthand discoveries made by these groups. The book emphasizes the fundamental principles of the structural-functional organization of the 3 major classes of genetic macromolecules: DNA, RNA and proteins. It also introduces universally applicable theoretical principles into the enormous realm of raw data and develops an integrative, theoretical computer approach to the analysis of these macromolecules to gain insights into the complexities of their function and evolution. Contents:Computer Analysis of Structural-Functional Organization of Nucleotide SequencesMobile Genetic Elements and Transposable Sequences: Principles of Structural-Functional Organization and EvolutionComputer Investigation of Molecular Mechanisms of MutagenesisInvestigation of Protein Structural-Functional Organization and EvolutionGenetic Macro-molecules: Principles and Mechanisms of Evolution Readership: Biochemists, computational scientists, geneticists, mathematicians and molecular biologists. keywords:Computer Analysis;Genetic Macromolecules;Evolution;DNA;RNA;Proteins;Bioinformatics;DNA/RNA Atructure;Gene Expression

Biological Sequence Analysis

Author : Richard Durbin
Publisher : Cambridge University Press
ISBN 13 : 113945739X
Total Pages : 372 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Biological Sequence Analysis by : Richard Durbin

Download or read book Biological Sequence Analysis written by Richard Durbin and published by Cambridge University Press. This book was released on 1998-04-23 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Probabilistic models are becoming increasingly important in analysing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analysing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it aims to be accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time present the state-of-the-art in this new and highly important field.

Molecular Evolution

Author : Vadim A. Ratner
Publisher : Springer Science & Business Media
ISBN 13 : 3662125307
Total Pages : 439 pages
Book Rating : 4.6/5 (621 download)

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Book Synopsis Molecular Evolution by : Vadim A. Ratner

Download or read book Molecular Evolution written by Vadim A. Ratner and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1970, Manfred Eigen initiated the study of the origin of self-reproducing systems of macromolecules and their evolution. Large-scale nucleotide sequencing (with computer methods) was introduced from 1977. The authors of this book, the first edition of which appeared (in Russian) in 1985, have been engaged in the research of the evolution of molecular genetic regulatory systems ever since those pioneering years. The book considers many fundamental problems of molecular biology, evolution, molecular genetic organization, the structure and function of macromolecules, always with the underlying motive of developing a unified theory. It describes many original, theoretical results as well as computational methods.

Sequence — Evolution — Function

Author : Eugene Koonin
Publisher : Springer Science & Business Media
ISBN 13 : 9781402072741
Total Pages : 496 pages
Book Rating : 4.0/5 (727 download)

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Book Synopsis Sequence — Evolution — Function by : Eugene Koonin

Download or read book Sequence — Evolution — Function written by Eugene Koonin and published by Springer Science & Business Media. This book was released on 2002-11-30 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.

Computer Methods for Macromolecular Sequence Analysis

Author : Russell F. Doolittle
Publisher : Academic Press
ISBN 13 :
Total Pages : 760 pages
Book Rating : 4.X/5 (2 download)

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Book Synopsis Computer Methods for Macromolecular Sequence Analysis by : Russell F. Doolittle

Download or read book Computer Methods for Macromolecular Sequence Analysis written by Russell F. Doolittle and published by Academic Press. This book was released on 1996-05-23 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume supplements Volume 183 in the "Methods in Enyzmology" series and complements Volume 224. It addresses a variety of areas in which computers are used to manage and manipulate macromolecular sequence data. The manipulations include searching, aligning and determining the significance of similarities as well as the construction of phylogenetic trees that show evolutionary history of related sequences

Molecular Biology of The Cell

Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Bibliography on Computational Molecular Biology and Genetics

Author : Sarah Barron
Publisher : DIANE Publishing
ISBN 13 : 9780941375917
Total Pages : 120 pages
Book Rating : 4.3/5 (759 download)

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Book Synopsis A Bibliography on Computational Molecular Biology and Genetics by : Sarah Barron

Download or read book A Bibliography on Computational Molecular Biology and Genetics written by Sarah Barron and published by DIANE Publishing. This book was released on 1991 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a definitive bibliographic review of the literature related to DNA mapping and sequence analysis, with a focus on computer and mathematical aspects of molecular biology and genetics. Over 2200 entries, arranged by author's name.

Electrophoresis, Supercomputing And The Human Genome - Proceedings Of The First International Conference

Author : Hwa A Lim
Publisher : World Scientific
ISBN 13 : 9814611484
Total Pages : 352 pages
Book Rating : 4.8/5 (146 download)

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Book Synopsis Electrophoresis, Supercomputing And The Human Genome - Proceedings Of The First International Conference by : Hwa A Lim

Download or read book Electrophoresis, Supercomputing And The Human Genome - Proceedings Of The First International Conference written by Hwa A Lim and published by World Scientific. This book was released on 1991-03-01 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the Conference and its proceedings is to provide a forum in which experts from both the academic and the industrial sectors as well as other interested individuals (young researchers and students) can gain a first hand knowledge of the scope, direction and future prospects in the international initiation of human genome research and its supporting technologies of electrophoresis and computing.

Practical Protein Bioinformatics

Author : Florencio Pazos
Publisher : Springer
ISBN 13 : 3319127276
Total Pages : 111 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Practical Protein Bioinformatics by : Florencio Pazos

Download or read book Practical Protein Bioinformatics written by Florencio Pazos and published by Springer. This book was released on 2014-11-28 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes more than 60 web-accessible computational tools for protein analysis and is totally practical, with detailed explanations on how to use these tools and interpret their results and minimal mentions to their theoretical basis (only when that is required for making a better use of them). It covers a wide range of tools for dealing with different aspects of proteins, from their sequences, to their three-dimensional structures, and the biological networks they are immersed in. The selection of tools is based on the experience of the authors that lead a protein bioinformatics facility in a large research centre, with the additional constraint that the tools should be accessible through standard web browsers without requiring the local installation of specific software, command-line tools, etc. The web tools covered include those aimed to retrieve protein information, look for similar proteins, generate pair-wise and multiple sequence alignments of protein sequences, work with protein domains and motifs, study the phylogeny of a family of proteins, retrieve, manipulate and visualize protein three-dimensional structures, predict protein structural features as well as whole three-dimensional structures, extract biological information from protein structures, summarize large protein sets, study protein interaction and metabolic networks, etc. The book is associated to a dynamic web site that will reflect changes in the web addresses of the tools, updates of these, etc. It also contains QR codes that can be scanned with any device to direct its browser to the tool web site. This monograph will be most valuable for researchers in experimental labs without specific knowledge on bioinformatics or computing.

Bioinformatics of Genome Regulation and Structure

Author : Nikolay Kolchanov
Publisher : Springer Science & Business Media
ISBN 13 : 1441971521
Total Pages : 373 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Bioinformatics of Genome Regulation and Structure by : Nikolay Kolchanov

Download or read book Bioinformatics of Genome Regulation and Structure written by Nikolay Kolchanov and published by Springer Science & Business Media. This book was released on 2013-06-05 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: - The data gathered can be used to solve a wide range of problems - for basic science and applied science

Biomacromolecules

Author : C. Stan Tsai
Publisher : John Wiley & Sons
ISBN 13 : 0470080116
Total Pages : 770 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Biomacromolecules by : C. Stan Tsai

Download or read book Biomacromolecules written by C. Stan Tsai and published by John Wiley & Sons. This book was released on 2007-01-16 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an integrated treatment of the structure and function of nucleic acids, proteins, and glycans, including thorough coverage of relevant computational biochemistry. The text begins with an introduction to the biomacromolecules, followed by discussion of methods of isolation and purification, physiochemical and biochemical properties, and structural characteristics. The next section of the book deals with sequence analysis, analysis of conformation using spectroscopy, chemical synthesis, and computational approaches. The following chapters discuss biomolecular interactions, enzyme action, gene transmission, signal transduction, and biomacromolecular informatics. The author concludes with presenting the latest findings in genomics, proteomics, glycomics, and biomacromolecular evolution. This text is an invaluable resource for research professionals wishing to move into genomics, proteomics, and glycomics research. It is also useful for students in biochemistry, molecular biology, bioengineering, biotechnology, and bioinformatics.

Handbook of Statistical Genetics

Author : David J. Balding
Publisher : John Wiley & Sons
ISBN 13 : 9780470997628
Total Pages : 1616 pages
Book Rating : 4.9/5 (976 download)

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Book Synopsis Handbook of Statistical Genetics by : David J. Balding

Download or read book Handbook of Statistical Genetics written by David J. Balding and published by John Wiley & Sons. This book was released on 2008-06-10 with total page 1616 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook for Statistical Genetics is widely regarded as the reference work in the field. However, the field has developed considerably over the past three years. In particular the modeling of genetic networks has advanced considerably via the evolution of microarray analysis. As a consequence the 3rd edition of the handbook contains a much expanded section on Network Modeling, including 5 new chapters covering metabolic networks, graphical modeling and inference and simulation of pedigrees and genealogies. Other chapters new to the 3rd edition include Human Population Genetics, Genome-wide Association Studies, Family-based Association Studies, Pharmacogenetics, Epigenetics, Ethic and Insurance. As with the second Edition, the Handbook includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between the chapters, tying the different areas together. With heavy use of up-to-date examples, real-life case studies and references to web-based resources, this continues to be must-have reference in a vital area of research. Edited by the leading international authorities in the field. David Balding - Department of Epidemiology & Public Health, Imperial College An advisor for our Probability & Statistics series, Professor Balding is also a previous Wiley author, having written Weight-of-Evidence for Forensic DNA Profiles, as well as having edited the two previous editions of HSG. With over 20 years teaching experience, he’s also had dozens of articles published in numerous international journals. Martin Bishop – Head of the Bioinformatics Division at the HGMP Resource Centre As well as the first two editions of HSG, Dr Bishop has edited a number of introductory books on the application of informatics to molecular biology and genetics. He is the Associate Editor of the journal Bioinformatics and Managing Editor of Briefings in Bioinformatics. Chris Cannings – Division of Genomic Medicine, University of Sheffield With over 40 years teaching in the area, Professor Cannings has published over 100 papers and is on the editorial board of many related journals. Co-editor of the two previous editions of HSG, he also authored a book on this topic.

Genetically Yours

Author : Hwa A. Lim
Publisher : World Scientific
ISBN 13 : 981024939X
Total Pages : 440 pages
Book Rating : 4.8/5 (12 download)

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Book Synopsis Genetically Yours by : Hwa A. Lim

Download or read book Genetically Yours written by Hwa A. Lim and published by World Scientific. This book was released on 2002 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers all the key aspects and current affairs in the field of biotechnology, with topics ranging from genome projects, through animal and human cloning, to biowarfare.

Novel Compounds From Natural Products In The New Millennium: Potential And Challenges

Author : Benny Kwong Huat Tan
Publisher : World Scientific
ISBN 13 : 9814481254
Total Pages : 337 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Novel Compounds From Natural Products In The New Millennium: Potential And Challenges by : Benny Kwong Huat Tan

Download or read book Novel Compounds From Natural Products In The New Millennium: Potential And Challenges written by Benny Kwong Huat Tan and published by World Scientific. This book was released on 2004-10-18 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is continuing interest in natural products as sources of potentially new and exciting chemical compounds. This book brings together the knowledge, perspectives and research findings of a varied group of scientists on a wide range of topics, from microarrays, genetics and bioinformatics to yeast-based technologies and enzyme studies. Scientists and clinicians in life science research will find useful information on new research techniques and tools. For the agriculturist, there is interesting information on the potential and problems of natural-based pesticides. The cancer researcher will find several plant sources with potential anti-cancer and immunomodulating compounds, as well as a report on two new modalities in cancer therapy — photosensitization with hypericin and immunotherapy. Latest developments of Chinese herbal extracts reported in this book may offer a new alternative therapy in the treatment of cardiovascular diseases. In addition, the later chapters awaken the would-be entrepreneur to the opportunities and challenges of research and development in the natural product industry, with the concluding chapter providing helpful insights into Intellectual Property Law.

Mathematical Methods of Analysis of Biopolymer Sequences

Author : Semen Grigorʹevich Gindikin
Publisher : American Mathematical Soc.
ISBN 13 : 9780821871157
Total Pages : 156 pages
Book Rating : 4.8/5 (711 download)

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Book Synopsis Mathematical Methods of Analysis of Biopolymer Sequences by : Semen Grigorʹevich Gindikin

Download or read book Mathematical Methods of Analysis of Biopolymer Sequences written by Semen Grigorʹevich Gindikin and published by American Mathematical Soc.. This book was released on with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection contains papers by participants in the seminar on mathematical methods in molecular biology who worked for several years at the Laboratory of Molecular Biology and Bioorganic Chemistry (now the Institute of Physical and Chemical Problems in Biology) at Moscow State University. The seminar united mathematicians and biologists around the problems of biological sequences. The collection includes original results as well as expository material and spans a range of perspectives, from purely mathematical problems to algorithms and their computer realizations. For this reason, the book is of interest to mathematicians, statisticians, biologists, and computational scientists who work with biopolymer sequences.

Bioinformatics, Supercomputing And Complex Genome Analysis - Proceedings Of The 2nd International Conference

Author : Hwa A Lim
Publisher : World Scientific
ISBN 13 : 9814602558
Total Pages : 682 pages
Book Rating : 4.8/5 (146 download)

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Book Synopsis Bioinformatics, Supercomputing And Complex Genome Analysis - Proceedings Of The 2nd International Conference by : Hwa A Lim

Download or read book Bioinformatics, Supercomputing And Complex Genome Analysis - Proceedings Of The 2nd International Conference written by Hwa A Lim and published by World Scientific. This book was released on 1993-09-07 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the beginning of the genome project, the necessary involvement of scientists of widely divergent backgrounds has been evident. The proper handling, analysis, dissemination of information, and the control and data gathering of automated process are areas where computers are directly involved. Thus computers are intimately tied into the production and analysis of biological data. However, many challenges lie ahead.This volume is a collection of selected oral and poster presentations given at The Second International Conference on Bioinformatics, Supercomputing and Complex Genome Analysis, organized to address some of these challenges. The topics include the current status and future prospects of genome map, mapping and sequencing, complex genome analysis,linguistic and neural network approaches, database issues, and computer tools in the genome project. The volume will be ideal for students, newcomers, young researchers and experts alike, who are computationally or experimentally oriented.Keynote Speakers: C L Smith, D Grothues, T Ito, T Sano, D Wang, Y-W Zhu, C R Canton & R J Rohins.