Computational studies of RNA and DNA

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Publisher : Springer Science & Business Media
ISBN 13 : 1402048513
Total Pages : 638 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Computational studies of RNA and DNA by : Jirí Šponer

Download or read book Computational studies of RNA and DNA written by Jirí Šponer and published by Springer Science & Business Media. This book was released on 2006-10-05 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book integrates modern computational studies of nucleic acids, ranging from advanced electronic structure quantum chemical calculations through explicit solvent molecular dynamics (MD) simulations up to mesoscopic modelling, with the main focus given to the MD field. It gives an equal emphasis to the leading methods and applications while successes as well as pitfalls of the computational techniques are discussed.

Computational Studies of DNA Structure and Recognition

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (592 download)

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Book Synopsis Computational Studies of DNA Structure and Recognition by : Christina Rebecca Grindon

Download or read book Computational Studies of DNA Structure and Recognition written by Christina Rebecca Grindon and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Computational Studies on DNA Structures

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Publisher :
ISBN 13 :
Total Pages : 158 pages
Book Rating : 4.:/5 (12 download)

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Book Synopsis Computational Studies on DNA Structures by : Yocheved Baime

Download or read book Computational Studies on DNA Structures written by Yocheved Baime and published by . This book was released on 2013 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Experimental and Computational Studies of DNA Structure Using the Hydroxyl Radical as a Chemical Probe

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Publisher :
ISBN 13 :
Total Pages : 388 pages
Book Rating : 4.:/5 (174 download)

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Book Synopsis Experimental and Computational Studies of DNA Structure Using the Hydroxyl Radical as a Chemical Probe by : Jason Adam Greenbaum

Download or read book Experimental and Computational Studies of DNA Structure Using the Hydroxyl Radical as a Chemical Probe written by Jason Adam Greenbaum and published by . This book was released on 2006 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Computational Molecular Biology

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Publisher : Elsevier
ISBN 13 : 008052964X
Total Pages : 663 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Computational Molecular Biology by : J. Leszczynski

Download or read book Computational Molecular Biology written by J. Leszczynski and published by Elsevier. This book was released on 1999-06-10 with total page 663 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers applications of computational techniques to biological problems. These techniques are based by an ever-growing number of researchers with different scientific backgrounds - biologists, chemists, and physicists. The rapid development of molecular biology in recent years has been mirrored by the rapid development of computer hardware and software. This has resulted in the development of sophisticated computational techniques and a wide range of computer simulations involving such methods. Among the areas where progress has been profound is in the modeling of DNA structure and function, the understanding at a molecular level of the role of solvents in biological phenomena, the calculation of the properties of molecular associations in aqueous solutions, computationally assisted drug design, the prediction of protein structure, and protein - DNA recognition, to mention just a few examples. This volume comprises a balanced blend of contributions covering such topics. They reveal the details of computational approaches designed for biomoleucles and provide extensive illustrations of current applications of modern techniques. A broad group of readers ranging from beginning graduate students to molecular biology professions should be able to find useful contributions in this selection of reviews.

Structural DNA Nanotechnology

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Publisher : Cambridge University Press
ISBN 13 : 0521764483
Total Pages : 269 pages
Book Rating : 4.5/5 (217 download)

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Book Synopsis Structural DNA Nanotechnology by : Nadrian C. Seeman

Download or read book Structural DNA Nanotechnology written by Nadrian C. Seeman and published by Cambridge University Press. This book was released on 2015 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the founder of the field, this is a comprehensive and accessible introduction to structural DNA nanotechnology.

The Alkali Metal Ions: Their Role for Life

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Publisher : Springer
ISBN 13 : 3319217569
Total Pages : 663 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis The Alkali Metal Ions: Their Role for Life by : Astrid Sigel

Download or read book The Alkali Metal Ions: Their Role for Life written by Astrid Sigel and published by Springer. This book was released on 2016-02-09 with total page 663 pages. Available in PDF, EPUB and Kindle. Book excerpt: MILS-16 provides an up-to-date review of the impact of alkali metal ions on life. Their bioinorganic chemistry and analytical determination, the solid state structures of bio-ligand complexes and the properties of alkali metal ions in solution in the context of all kinds of biologically relevant ligands are covered, this includes proteins (enzymes) and nucleic acids (G-quadruplexes). Minerals containing sodium (Na+) and potassium (K+) are abundant in the Earth's crust, making Na+ and K+ easily available. In contrast, the alkali elements lithium (Li+), rubidium, and cesium are rare and the radioactive francium occurs only in traces. Since the intra- and extracellular, as well as the compartmental concentrations of Na+ and K+ differ significantly, homeostasis and active transport of these ions are important; this involves transporters/carriers and pore-forming ion channel proteins. Systems like Na+/K+-ATPases, H+/K+-ATPases or Na+/H+ antiporters are thoroughly discussed. The role of K+ in photosynthesis and the role of Na+ in charging the "battery of life" are pointed out. Also, the relationships between alkali metal ions and diseases (e.g., Parkinson or traumatic brain injury) are covered and the relevance of Li+ salts in medicine (pharmacology and mechanism) is reviewed. This and more is treated in an authoritative and timely manner in the 16 stimulating chapters of Volume 16, The Alkali Metal Ions: Their Role for Life, which are written by 44 internationally recognized experts from 12 nations. The impact of this vibrant research area is manifested in nearly 3000 references, over 30 tables and more than 150 illustrations (two thirds in color). MILS-16 also provides excellent information for teaching. Astrid Sigel, Helmut Sigel, and Roland K. O. Sigel have long-standing interests in Biological Inorganic Chemistry. Their research focuses on metal ion interactions with nucleotides and nucleic acids and on related topics. They edited previously 44 volumes in the series Metal Ions in Biological Systems.

Radiation Induced Molecular Phenomena in Nucleic Acids

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Publisher : Springer Science & Business Media
ISBN 13 : 1402081847
Total Pages : 677 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Radiation Induced Molecular Phenomena in Nucleic Acids by : Manoj Shukla

Download or read book Radiation Induced Molecular Phenomena in Nucleic Acids written by Manoj Shukla and published by Springer Science & Business Media. This book was released on 2008-05-08 with total page 677 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive theoretical and experimental analysis of UV-radiation and low energy electron induced phenomena in nucleic acid bases (NABs) and base assemblies are presented in this book. NABs are highly photostable; the absorbed energy is dissipated in the form of ultrafast nonradiative decay. This book highlights the possible mechanisms of these phenomena which is important for all living species and discusses technical challenges in exploration of these processes.

Advances in Computational Biology

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Publisher : Elsevier
ISBN 13 : 008052611X
Total Pages : 281 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Advances in Computational Biology by : H.O. Villar

Download or read book Advances in Computational Biology written by H.O. Villar and published by Elsevier. This book was released on 1996-05-31 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second volume in a series which aims to focus on advances in computational biology. This volume discusses such topics as: statistical analysis of protein sequences; progress in large-scale sequence analysis; and the architecture of loops in proteins.

Biological Sequence Analysis

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Publisher : Cambridge University Press
ISBN 13 : 113945739X
Total Pages : 372 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Biological Sequence Analysis by : Richard Durbin

Download or read book Biological Sequence Analysis written by Richard Durbin and published by Cambridge University Press. This book was released on 1998-04-23 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Probabilistic models are becoming increasingly important in analysing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analysing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it aims to be accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time present the state-of-the-art in this new and highly important field.

DNA Computing and Molecular Programming

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Publisher : Springer
ISBN 13 : 3319667998
Total Pages : 278 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis DNA Computing and Molecular Programming by : Robert Brijder

Download or read book DNA Computing and Molecular Programming written by Robert Brijder and published by Springer. This book was released on 2017-08-22 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 23th International Conference on DNA Computing and Molecular Programming, DNA 23, held Austin, TX, USA, in September 2017. The 16 full papers presented were carefully selected from 23 submissions. Research in DNA computing aims to draw together mathematics, computerscience, physics, chemistry, biology, and nanotechnology to address the analysis, design, and synthesis of information-based molecular systems. The papers address all areas related to biomolecular computing such as: algorithms and models for computation with biomolecular systems; computational processes in vitro and in vivo; molecular motors and molecular robotics; studies of fault-tolerance and error correction; software tools for analysis, simulation, and design; synthetic biology and in vitro evolution; applications in engineering, physics, chemistry, biology, and medicine.

Algorithms in Computational Molecular Biology

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Publisher : John Wiley & Sons
ISBN 13 : 1118101987
Total Pages : 1027 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Algorithms in Computational Molecular Biology by : Mourad Elloumi

Download or read book Algorithms in Computational Molecular Biology written by Mourad Elloumi and published by John Wiley & Sons. This book was released on 2011-04-04 with total page 1027 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents the most comprehensive and up-to-date collection of information on the topic of computational molecular biology. Bringing the most recent research into the forefront of discussion, Algorithms in Computational Molecular Biology studies the most important and useful algorithms currently being used in the field, and provides related problems. It also succeeds where other titles have failed, in offering a wide range of information from the introductory fundamentals right up to the latest, most advanced levels of study.

Computational Studies of Stabilisation of DNA Holliday Junctions and G-quadruplexes by Novel DACA Analogues

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (111 download)

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Book Synopsis Computational Studies of Stabilisation of DNA Holliday Junctions and G-quadruplexes by Novel DACA Analogues by : Subramanian Arun Kumar

Download or read book Computational Studies of Stabilisation of DNA Holliday Junctions and G-quadruplexes by Novel DACA Analogues written by Subramanian Arun Kumar and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 9-aminoacridine-4-carboxamide (DACA) derivatives are 3-membered aromatic ring systems having good recognition of nucleic acids. Extensive computational experiments have been deployed to study the drug induced binding effects on DNA structures and the efficiency of drug binding using several molecular modelling methods.

Mathematics of DNA Structure, Function and Interactions

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Publisher : Springer Science & Business Media
ISBN 13 : 1441906711
Total Pages : 359 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Mathematics of DNA Structure, Function and Interactions by : Craig John Benham

Download or read book Mathematics of DNA Structure, Function and Interactions written by Craig John Benham and published by Springer Science & Business Media. This book was released on 2010-04-29 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Propelled by the success of the sequencing of the human and many related genomes, molecular and cellular biology has delivered significant scientific breakthroughs. Mathematics (broadly defined) continues to play a major role in this effort, helping to discover the secrets of life by working collaboratively with bench biologists, chemists and physicists. Because of its outstanding record of interdisciplinary research and training, the IMA was an ideal venue for the 2007-2008 IMA thematic year on Mathematics of Molecular and Cellular Biology. The kickoff event for this thematic year was a tutorial on Mathematics of Nucleic Acids, followed by the workshop Mathematics of Molecular and Cellular Biology, held September 15--21 at the IMA. This volume is dedicated to the memory of Nicholas R. Cozzarelli, a dynamic leader who fostered research and training at the interface between mathematics and molecular biology. It contains a personal remembrance of Nick Cozzarelli, plus 15 papers contributed by workshop speakers. The papers give an overview of state-of-the-art mathematical approaches to the understanding of DNA structure and function, and the interaction of DNA with proteins that mediate vital life processes.

Principles of Nucleic Acid Structure

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Publisher : Springer Science & Business Media
ISBN 13 : 1461251907
Total Pages : 574 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Principles of Nucleic Acid Structure by : Wolfram Saenger

Download or read book Principles of Nucleic Acid Structure written by Wolfram Saenger and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: New textbooks at all levels of chemistry appear with great regularity. Some fields like basic biochemistry, organic reaction mechanisms, and chemical ther modynamics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the grad uate level, suffer from a real lack of up-to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research which is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive introductions to their fields. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. In some cases the availability of texts in active research areas should help stimulate the creation of new courses. CHARLES R. CANTOR New York Preface This monograph is based on a review on polynucleotide structures written for a book series in 1976.

Computational Studies of Damaged DNA

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (122 download)

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Book Synopsis Computational Studies of Damaged DNA by : Mohadeseh Majdi Yazdi

Download or read book Computational Studies of Damaged DNA written by Mohadeseh Majdi Yazdi and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis systematically develops a computational model to identify the conformational and base-pairing preferences of PhOdG, 4-Cl-PhOdG, DCP-OdG, TCP-OdG, and PCP-OdG by gradually increasing the size of the system also structural properties of unsubstituted O-linked. All adducts at nucleoside level adopted syn conformation. Moreover, effect of protonation at N3 and N7 site on the structural properties and deglycosilation barrier of adducted guanosine was probed. It was highly desirable to include O-linked phenolic as well as C8-dG adducts into a DNA strand in order to understand the detrimental effect of them and the conformational distortion of double helix duplex the desired modified base into NarI DNA duplex through the employment of molecular dynamic simulation (MD) was assessed. The anti-conformation against cytosine is preferred with this model for all adducts and syn conformer for all unsubstituted O-linked and ortho and para Clinked structures against guanine mismatch is the lowest energy structure.

Computational Biology and Genome Informatics

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Publisher : World Scientific
ISBN 13 : 9812382577
Total Pages : 266 pages
Book Rating : 4.8/5 (123 download)

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Book Synopsis Computational Biology and Genome Informatics by : Jason T. L. Wang

Download or read book Computational Biology and Genome Informatics written by Jason T. L. Wang and published by World Scientific. This book was released on 2003 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains articles written by experts on a wide range of topics that are associated with the analysis and management of biological information at the molecular level. It contains chapters on RNA and protein structure analysis, DNA computing, sequence mapping, genome comparison, gene expression data mining, metabolic network modeling, and phyloinformatics. The important work of some representative researchers in bioinformatics is brought together for the first time in one volume. The topic is treated in depth and is related to, where applicable, other emerging technologies such as data mining and visualization. The goal of the book is to introduce readers to the principle techniques of bioinformatics in the hope that they will build on them to make new discoveries of their own. Contents: Exploring RNA Intermediate Conformations with the Massively Parallel Genetic Algorithm; Introduction to Self-Assembling DNA Nanostructures for Computation and Nanofabrication; Mapping Sequence to Rice FPC; Graph Theoretic Sequence Clustering Algorithms and their Applications to Genome Comparison; The Protein Information Resource for Functional Genomics and Proteomics; High-Grade Ore for Data Mining in 3D Structures; Protein Classification: A Geometric Hashing Approach; Interrelated Clustering: An Approach for Gene Expression Data Analysis; Creating Metabolic Network Models Using Text Mining and Expert Knowledge; Phyloinformatics and Tree Networks. Readership: Molecular biologists who rely on computers and mathematical scientists with interests in biology.