Computational Methods For Predicting Post Translational Modification Sites

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Computational Methods for Predicting Post-Translational Modification Sites

Author : Dukka B. KC
Publisher : Springer Nature
ISBN 13 : 1071623176
Total Pages : 337 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Computational Methods for Predicting Post-Translational Modification Sites by : Dukka B. KC

Download or read book Computational Methods for Predicting Post-Translational Modification Sites written by Dukka B. KC and published by Springer Nature. This book was released on 2022-06-13 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume describes computational approaches to predict multitudes of PTM sites. Chapters describe in depth approaches on algorithms, state-of-the-art Deep Learning based approaches, hand-crafted features, physico-chemical based features, issues related to obtaining negative training, sequence-based features, and structure-based features. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Authoritative and cutting-edge, Computational Methods for Predicting Post-Translational Modification Sites aims to be a useful guide for researchers who are interested in the field of PTM site prediction.

Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics

Author : Yi Pan
Publisher : John Wiley & Sons
ISBN 13 : 1118567811
Total Pages : 534 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics by : Yi Pan

Download or read book Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics written by Yi Pan and published by John Wiley & Sons. This book was released on 2013-10-07 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics An in-depth look at the latest research, methods, and applications in the field of protein bioinformatics This book presents the latest developments in protein bioinformatics, introducing for the first time cutting-edge research results alongside novel algorithmic and AI methods for the analysis of protein data. In one complete, self-contained volume, Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics addresses key challenges facing both computer scientists and biologists, arming readers with tools and techniques for analyzing and interpreting protein data and solving a variety of biological problems. Featuring a collection of authoritative articles by leaders in the field, this work focuses on the analysis of protein sequences, structures, and interaction networks using both traditional algorithms and AI methods. It also examines, in great detail, data preparation, simulation, experiments, evaluation methods, and applications. Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics: Highlights protein analysis applications such as protein-related drug activity comparison Incorporates salient case studies illustrating how to apply the methods outlined in the book Tackles the complex relationship between proteins from a systems biology point of view Relates the topic to other emerging technologies such as data mining and visualization Includes many tables and illustrations demonstrating concepts and performance figures Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics is an essential reference for bioinformatics specialists in research and industry, and for anyone wishing to better understand the rich field of protein bioinformatics.

Computational Resources for Understanding Biomacromolecular Covalent Modifications

Author : Dong Xu
Publisher : Frontiers Media SA
ISBN 13 : 2889713199
Total Pages : 110 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Computational Resources for Understanding Biomacromolecular Covalent Modifications by : Dong Xu

Download or read book Computational Resources for Understanding Biomacromolecular Covalent Modifications written by Dong Xu and published by Frontiers Media SA. This book was released on 2021-09-14 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Developability of Biotherapeutics

Author : Sandeep Kumar
Publisher : CRC Press
ISBN 13 : 1482246155
Total Pages : 312 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Developability of Biotherapeutics by : Sandeep Kumar

Download or read book Developability of Biotherapeutics written by Sandeep Kumar and published by CRC Press. This book was released on 2015-11-18 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biopharmaceuticals are emerging as frontline medicines to combat several life-threatening and chronic diseases. However, such medicines are expensive to develop and produce on a commercial scale, contributing to rising healthcare costs. Developability of Biotherapeutics: Computational Approaches describes applications of computational and molecular

Concepts and Techniques in Genomics and Proteomics

Author : N Saraswathy
Publisher : Elsevier
ISBN 13 : 1908818050
Total Pages : 271 pages
Book Rating : 4.9/5 (88 download)

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Book Synopsis Concepts and Techniques in Genomics and Proteomics by : N Saraswathy

Download or read book Concepts and Techniques in Genomics and Proteomics written by N Saraswathy and published by Elsevier. This book was released on 2011-07-01 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concepts and techniques in genomics and proteomics covers the important concepts of high-throughput modern techniques used in the genomics and proteomics field. Each technique is explained with its underlying concepts, and simple line diagrams and flow charts are included to aid understanding and memory. A summary of key points precedes each chapter within the book, followed by detailed description in the subsections. Each subsection concludes with suggested relevant original references. - Provides definitions for key concepts - Case studies are included to illustrate ideas - Important points to remember are noted

An Introduction to Computational Biochemistry

Author : C. Stan Tsai
Publisher : John Wiley & Sons
ISBN 13 : 0471461091
Total Pages : 381 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis An Introduction to Computational Biochemistry by : C. Stan Tsai

Download or read book An Introduction to Computational Biochemistry written by C. Stan Tsai and published by John Wiley & Sons. This book was released on 2003-03-31 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive text offers a solid introduction to the biochemical principles and skills required for any researcher applying computational tools to practical problems in biochemistry. Each chapter includes an introduction to the topic, a review of the biological concepts involved, a discussion of the programming and applications used, key references, and problem sets and answers. Providing detailed coverage of biochemical structures, enzyme reactions, metabolic simulation, genomic and proteomic analyses, and molecular modeling, this is the perfect resource for students and researchers in biochemistry, bioinformatics, bioengineering and computational science.

The Proteomics Protocols Handbook

Author : John M. Walker
Publisher : Springer Science & Business Media
ISBN 13 : 1592598900
Total Pages : 969 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis The Proteomics Protocols Handbook by : John M. Walker

Download or read book The Proteomics Protocols Handbook written by John M. Walker and published by Springer Science & Business Media. This book was released on 2007-10-09 with total page 969 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hands-on researchers describe in step-by-step detail 73 proven laboratory methods and bioinformatics tools essential for analysis of the proteome. These cutting-edge techniques address such important tasks as sample preparation, 2D-PAGE, gel staining, mass spectrometry, and post-translational modification. There are also readily reproducible methods for protein expression profiling, identifying protein-protein interactions, and protein chip technology, as well as a range of newly developed methodologies for determining the structure and function of a protein. The bioinformatics tools include those for analyzing 2D-GEL patterns, protein modeling, and protein identification. All laboratory-based protocols follow the successful Methods in Molecular BiologyTM series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

Encyclopedia of Bioinformatics and Computational Biology

Author :
Publisher : Elsevier
ISBN 13 : 0128114320
Total Pages : 3421 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Encyclopedia of Bioinformatics and Computational Biology by :

Download or read book Encyclopedia of Bioinformatics and Computational Biology written by and published by Elsevier. This book was released on 2018-08-21 with total page 3421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Issues in Proteins and Peptides Research and Application: 2013 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1490108009
Total Pages : 1105 pages
Book Rating : 4.4/5 (91 download)

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Book Synopsis Issues in Proteins and Peptides Research and Application: 2013 Edition by :

Download or read book Issues in Proteins and Peptides Research and Application: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-05-01 with total page 1105 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Proteins and Peptides Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Peptide Science. The editors have built Issues in Proteins and Peptides Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Peptide Science in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Proteins and Peptides Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Agricultural Bioinformatics

Author : Kavi Kishor P.B.
Publisher : Springer
ISBN 13 : 8132218809
Total Pages : 296 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Agricultural Bioinformatics by : Kavi Kishor P.B.

Download or read book Agricultural Bioinformatics written by Kavi Kishor P.B. and published by Springer. This book was released on 2014-07-14 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: A common approach to understanding the functional repertoire of a genome is through functional genomics. With systems biology burgeoning, bioinformatics has grown to a larger extent for plant genomes where several applications in the form of protein-protein interactions (PPI) are used to predict the function of proteins. With plant genes evolutionarily conserved, the science of bioinformatics in agriculture has caught interest with myriad of applications taken from bench side to in silico studies. A multitude of technologies in the form of gene analysis, biochemical pathways and molecular techniques have been exploited to an extent that they consume less time and have been cost-effective to use. As genomes are being sequenced, there is an increased amount of expression data being generated from time to time matching the need to link the expression profiles and phenotypic variation to the underlying genomic variation. This would allow us to identify candidate genes and understand the molecular basis/phenotypic variation of traits. While many bioinformatics methods like expression and whole genome sequence data of organisms in biological databases have been used in plants, we felt a common reference showcasing the reviews for such analysis is wanting. We envisage that this dearth would be facilitated in the form of this Springer book on Agricultural Bioinformatics. We thank all the authors and the publishers Springer, Germany for providing us an opportunity to review the bioinformatics works that the authors have carried in the recent past and hope the readers would find this book attention grabbing.

Redox Chemistry and Biology of Thiols

Author : Beatriz Alvarez
Publisher : Academic Press
ISBN 13 : 0323915663
Total Pages : 748 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Redox Chemistry and Biology of Thiols by : Beatriz Alvarez

Download or read book Redox Chemistry and Biology of Thiols written by Beatriz Alvarez and published by Academic Press. This book was released on 2022-05-25 with total page 748 pages. Available in PDF, EPUB and Kindle. Book excerpt: Redox Chemistry and Biology of Thiols offers an applied, comprehensive overview of redox chemistry and biology of thiol-dependent processes. Running from basic biology and chemistry of redox phenomena to research methods and highlighting recently identified roles of thiols across cellular and bodily systems, this book draws upon a range of disciplines to illuminate new research directions, new applications of thiol studies, and clinical translation. Sections cover thiol oxidizing species, thiol reactivity and modifications, thioredoxin, glutaredoxin, glutathione, peroxidases, thiol repair enzymes, thiol oxidative signaling, disulfide bond formation, thiol-based redox biosensors, cysteine and hydrogen sulfide metabolism, iron-sulfur cluster biogenesis, thiols in chloroplasts, blood thiols, sugar and polyamine thiols in pathogenic organisms, redox medicine (therapeutic applications of thiols and drug development), as well as methods and bioinformatics tools. - Runs from basic thiol biology and chemistry to applications and clinical translation - Provides methods and protocols that will power new research across biomedicine, cell biology, plant biology, drug development, and protein folding and modulation - Includes chapter contributions from international leaders in the field

Proteins

Author : Thomas E. Creighton
Publisher : Macmillan
ISBN 13 : 9780716770305
Total Pages : 534 pages
Book Rating : 4.7/5 (73 download)

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Book Synopsis Proteins by : Thomas E. Creighton

Download or read book Proteins written by Thomas E. Creighton and published by Macmillan. This book was released on 1993 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organized on a combined basis of chronology and of structural and functional hierarchy, This comprehensive text describes all aspects of proteins--biosynthesis, evolution, dynamics, ligand binding, catalysis, and energy transduction--not just their structures. This edition (first was 1984) is thoroughly updated--especially in the area of protein biosynthesis--and features end-of-chapter exercises and problems, many of which require the student to consult the cited literature in order to obtain the answer. Annotation copyright by Book News, Inc., Portland, OR

Post-translational Modifications of Proteins

Author : Christoph Kannicht
Publisher : Humana Press
ISBN 13 : 9781588297198
Total Pages : 0 pages
Book Rating : 4.2/5 (971 download)

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Book Synopsis Post-translational Modifications of Proteins by : Christoph Kannicht

Download or read book Post-translational Modifications of Proteins written by Christoph Kannicht and published by Humana Press. This book was released on 2008-04-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a fully up-dated and expanded practical guide to protein structure-function relationships. This important area of research is brought up-to-date by the leading scientists in the field. The compilation of detailed protocols focuses on protein function, proteome research and characterization of pharmaceutical proteins, while following the successful format of the Methods in Molecular BiologyTM series. Comprehensive and cutting edge, the book serves as practical guide for researchers working in the field of protein structure-function relationships and the rapidly growing field of proteomics, as well as scientists in the pharmaceutical industries.

Prediction of Protein Structure and the Principles of Protein Conformation

Author : G.D. Fasman
Publisher : Springer Science & Business Media
ISBN 13 : 1461315719
Total Pages : 796 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Prediction of Protein Structure and the Principles of Protein Conformation by : G.D. Fasman

Download or read book Prediction of Protein Structure and the Principles of Protein Conformation written by G.D. Fasman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 796 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prediction of the conformation of proteins has developed from an intellectual exercise into a serious practical endeavor that has great promise to yield new stable enzymes, products of pharmacological significance, and catalysts of great potential. With the application of predic tion gaining momentum in various fields, such as enzymology and immunology, it was deemed time that a volume be published to make available a thorough evaluation of present methods, for researchers in this field to expound fully the virtues of various algorithms, to open the field to a wider audience, and to offer the scientific public an opportunity to examine carefully its successes and failures. In this manner the practitioners of the art could better evaluate the tools and the output so that their expectations and applications could be more realistic. The editor has assembled chapters by many of the main contributors to this area and simultaneously placed their programs at three national resources so that they are readily available to those who wish to apply them to their personal interests. These algorithms, written by their originators, when utilized on pes or larger computers, can instantaneously take a primary amino acid sequence and produce a two-or three-dimensional artistic image that gives satisfaction to one's esthetic sensibilities and food for thought concerning the structure and function of proteins. It is in this spirit that this volume was envisaged.

Chemoinformatics and Advanced Machine Learning Perspectives: Complex Computational Methods and Collaborative Techniques

Author : Lodhi, Huma
Publisher : IGI Global
ISBN 13 : 1615209123
Total Pages : 418 pages
Book Rating : 4.6/5 (152 download)

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Book Synopsis Chemoinformatics and Advanced Machine Learning Perspectives: Complex Computational Methods and Collaborative Techniques by : Lodhi, Huma

Download or read book Chemoinformatics and Advanced Machine Learning Perspectives: Complex Computational Methods and Collaborative Techniques written by Lodhi, Huma and published by IGI Global. This book was released on 2010-07-31 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book is a timely compendium of key elements that are crucial for the study of machine learning in chemoinformatics, giving an overview of current research in machine learning and their applications to chemoinformatics tasks"--Provided by publisher.

Machine Learning In Bioinformatics Of Protein Sequences: Algorithms, Databases And Resources For Modern Protein Bioinformatics

Author : Lukasz Kurgan
Publisher : World Scientific
ISBN 13 : 9811258597
Total Pages : 378 pages
Book Rating : 4.8/5 (112 download)

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Book Synopsis Machine Learning In Bioinformatics Of Protein Sequences: Algorithms, Databases And Resources For Modern Protein Bioinformatics by : Lukasz Kurgan

Download or read book Machine Learning In Bioinformatics Of Protein Sequences: Algorithms, Databases And Resources For Modern Protein Bioinformatics written by Lukasz Kurgan and published by World Scientific. This book was released on 2022-12-06 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Machine Learning in Bioinformatics of Protein Sequences guides readers around the rapidly advancing world of cutting-edge machine learning applications in the protein bioinformatics field. Edited by bioinformatics expert, Dr Lukasz Kurgan, and with contributions by a dozen of accomplished researchers, this book provides a holistic view of the structural bioinformatics by covering a broad spectrum of algorithms, databases and software resources for the efficient and accurate prediction and characterization of functional and structural aspects of proteins. It spotlights key advances which include deep neural networks, natural language processing-based sequence embedding and covers a wide range of predictions which comprise of tertiary structure, secondary structure, residue contacts, intrinsic disorder, protein, peptide and nucleic acids-binding sites, hotspots, post-translational modification sites, and protein function. This volume is loaded with practical information that identifies and describes leading predictive tools, useful databases, webservers, and modern software platforms for the development of novel predictive tools.

Kinomics

Author : Heinz-Bernhard Kraatz
Publisher : John Wiley & Sons
ISBN 13 : 3527337652
Total Pages : 364 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Kinomics by : Heinz-Bernhard Kraatz

Download or read book Kinomics written by Heinz-Bernhard Kraatz and published by John Wiley & Sons. This book was released on 2015-11-16 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Das umfassende Referenzwerk zur Kinase-Forschung: Ausführlich werden die Themen Kinase-Engineering, Peptidsubstrat-Engineering, das Design von Co-Substraten und Kinasehemmer erläutert sowie deren Anwendung in der Bio- und Pharmaforschung beschrieben.