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Computational Fluid Particle Dynamics Modeling For Unconventional Inhaled Aerosols In Human Respiratory Systems
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Download or read book Aerosols written by Konstantin Volkov and published by BoD – Books on Demand. This book was released on 2016-12-28 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aerosols have a significant impact on technological processes and human activities. In many cases, aerosols are at the core of human health, environmental and technological problems (climate change and air quality). However, aerosols can be successfully used in industry and technology (new materials, fire suppression and fuel delivery). The current scientific status of aerosol modelling and simulation and measurements and some advances in computational techniques, particle measurement technologies and practical applications of aerosols are reviewed and considered in this book. This book also includes a number of case studies focused on analysis of optical thickness and air quality in various regions.
Book Synopsis Computational Fluid and Particle Dynamics in the Human Respiratory System by : Jiyuan Tu
Download or read book Computational Fluid and Particle Dynamics in the Human Respiratory System written by Jiyuan Tu and published by Springer Science & Business Media. This book was released on 2012-09-18 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditional research methodologies in the human respiratory system have always been challenging due to their invasive nature. Recent advances in medical imaging and computational fluid dynamics (CFD) have accelerated this research. This book compiles and details recent advances in the modelling of the respiratory system for researchers, engineers, scientists, and health practitioners. It breaks down the complexities of this field and provides both students and scientists with an introduction and starting point to the physiology of the respiratory system, fluid dynamics and advanced CFD modeling tools. In addition to a brief introduction to the physics of the respiratory system and an overview of computational methods, the book contains best-practice guidelines for establishing high-quality computational models and simulations. Inspiration for new simulations can be gained through innovative case studies as well as hands-on practice using pre-made computational code. Last but not least, students and researchers are presented the latest biomedical research activities, and the computational visualizations will enhance their understanding of physiological functions of the respiratory system.
Book Synopsis Pharmaceutical Inhalation Aerosol Technology, Third Edition by : Anthony J. Hickey
Download or read book Pharmaceutical Inhalation Aerosol Technology, Third Edition written by Anthony J. Hickey and published by CRC Press. This book was released on 2019-03-26 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully revised and updated third edition of Pharmaceutical Inhalation Aerosol Technology encompasses the scientific and technical foundation for the rationale, design, componentry, assembly and quality performance metrics of therapeutic inhalers in their delivery of pharmaceutical aerosols to treat symptoms or the underlying causes of disease. It focuses on the importance of pharmaceutical engineering as a foundational element of all inhaler products and their application to pulmonary drug delivery. The expanded scope considers previously unaddressed aspects of pharmaceutical inhalation aerosol technology and the patient interface by including aerosol delivery, lung deposition and clearance that are used as measures of effective dose delivery. Key Features: Provides a thoroughly revised and expanded reference with authoritative discussions on the physiologic,pharmacologic, metabolic, molecular, cellular and physicochemical factors, influencing the efficacy and utilization of pharmaceutical aerosols Emphasizes the importance of pharmaceutical engineering as a foundational element of all inhaler products and their application to pulmonary drug delivery Addresses the physics, chemistry and engineering principles while establishing disease relevance Expands the ‘technology’ focus of the original volumes to address the title more directly Offers an impressive breadth of coverage as well as an international flavour from outstanding editors and contributors
Book Synopsis Toxicological Evaluation of Electronic Nicotine Delivery Products by : Manuel C. Peitsch
Download or read book Toxicological Evaluation of Electronic Nicotine Delivery Products written by Manuel C. Peitsch and published by Academic Press. This book was released on 2021-01-14 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicological Evaluation of Electronic Nicotine Delivery Products (ENDP) discusses the scientific basis for the toxicological assessment and evaluation of ENDPs. The book covers aerosol chemistry, in vitro and in vivo studies as well as clinical studies. It provides the basis for the evaluation of short and long term-effects, along with relative risks. It also examines the potential role of ENDPs in tobacco harm reduction and how they may reduce the risk of disease in smokers who switch to them. This book is a comprehensive resource for toxicologists, health practitioners and public health professionals who want the scientific information necessary to assess the relative risk of ENDPs when compared with cigarette smoking and cessation. - Delivers a comprehensive overview of current state of science - Offers an integrated analysis of e-cigarettes and heated tobacco products - Provides guidance for methodologies
Book Synopsis Materials, Design, and Manufacturing for Sustainable Environment by : Santhakumar Mohan
Download or read book Materials, Design, and Manufacturing for Sustainable Environment written by Santhakumar Mohan and published by Springer Nature. This book was released on 2021-02-06 with total page 909 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprises the select proceedings of the International Conference on Materials, Design and Manufacturing for Sustainable Environment (ICMDMSE 2020). The primary focus is on emerging materials and cutting-edge manufacturing technologies for sustainable environment. The book covers a wide range of topics such as advanced materials, vibration, tribology, finite element method (FEM), heat transfer, fluid mechanics, energy engineering, additive manufacturing, robotics and automation, automobile engineering, industry 4.0, MEMS and nanotechnology, optimization techniques, condition monitoring, and new paradigms in technology management. Contents of this book will be useful to students, researchers, and practitioners alike.
Book Synopsis Aerosols €“ Science and Case Studies by :
Download or read book Aerosols €“ Science and Case Studies written by and published by . This book was released on 19?? with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Inhalation Aerosols by : Anthony J. Hickey
Download or read book Inhalation Aerosols written by Anthony J. Hickey and published by CRC Press. This book was released on 2019-03-21 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inhalation aerosols continue to be the basis for successful lung therapy for several diseases, with therapeutic strategies and the range of technology significantly evolving in recent years. In response, this third edition takes a new approach to reflect the close integration of technology with its application. After briefly presenting the general considerations that apply to aerosol inhalation, the central section of the book uses the focus on disease and therapeutic agents to illustrate the application of specific technologies. The final integrated strategies section draws the major points from the applications for disease targets and drug products.
Book Synopsis Heat Transfer and Fluid Flow in Biological Processes by : Sid M. Becker
Download or read book Heat Transfer and Fluid Flow in Biological Processes written by Sid M. Becker and published by Academic Press. This book was released on 2014-12-31 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heat Transfer and Fluid Flow in Biological Processes covers emerging areas in fluid flow and heat transfer relevant to biosystems and medical technology. This book uses an interdisciplinary approach to provide a comprehensive prospective on biofluid mechanics and heat transfer advances and includes reviews of the most recent methods in modeling of flows in biological media, such as CFD. Written by internationally recognized researchers in the field, each chapter provides a strong introductory section that is useful to both readers currently in the field and readers interested in learning more about these areas. Heat Transfer and Fluid Flow in Biological Processes is an indispensable reference for professors, graduate students, professionals, and clinical researchers in the fields of biology, biomedical engineering, chemistry and medicine working on applications of fluid flow, heat transfer, and transport phenomena in biomedical technology. - Provides a wide range of biological and clinical applications of fluid flow and heat transfer in biomedical technology - Covers topics such as electrokinetic transport, electroporation of cells and tissue dialysis, inert solute transport (insulin), thermal ablation of cancerous tissue, respiratory therapies, and associated medical technologies - Reviews the most recent advances in modeling techniques
Book Synopsis Clinical and Biomedical Engineering in the Human Nose by : Kiao Inthavong
Download or read book Clinical and Biomedical Engineering in the Human Nose written by Kiao Inthavong and published by Springer Nature. This book was released on 2020-10-16 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores computational fluid dynamics in the context of the human nose, allowing readers to gain a better understanding of its anatomy and physiology and integrates recent advances in clinical rhinology, otolaryngology and respiratory physiology research. It focuses on advanced research topics, such as virtual surgery, AI-assisted clinical applications and therapy, as well as the latest computational modeling techniques, controversies, challenges and future directions in simulation using CFD software. Presenting perspectives and insights from computational experts and clinical specialists (ENT) combined with technical details of the computational modeling techniques from engineers, this unique reference book will give direction to and inspire future research in this emerging field.
Book Synopsis Nanoparticle Heat Transfer and Fluid Flow by : W. J. Minkowycz
Download or read book Nanoparticle Heat Transfer and Fluid Flow written by W. J. Minkowycz and published by CRC Press. This book was released on 2016-04-19 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Featuring contributions by leading researchers in the field, Nanoparticle Heat Transfer and Fluid Flow explores heat transfer and fluid flow processes in nanomaterials and nanofluids, which are becoming increasingly important across the engineering disciplines. The book covers a wide range, from biomedical and energy conversion applications to mate
Book Synopsis Morphometry of the Human Lung by : Ewald R. Weibel
Download or read book Morphometry of the Human Lung written by Ewald R. Weibel and published by Academic Press. This book was released on 2013-10-22 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Morphometry of the Human Lung considers the developments in understanding the quantitative anatomy of the lung, and in the correlation of anatomy with physiology. This book is composed of 11 chapters, and begins with an overview of a systematic approach to a quantitative morphologic analysis of the architecture of the human lung, followed by a presentation of general problems of methodology and the derivation of reliable dimensional models of this organ. The subsequent chapters describe the methods of preparation of tissues, methods of random sampling, and adaptation of methodologies from other fields of science. These topics are followed by discussions the mathematical formulations for the translation of the data into the desired geometric forms and a technique of counting. The final chapters look into the mode of distribution and geometric forms that should eventually facilitate mathematical and physical considerations regarding the function of the lungs. These chapters also consider the application of these quantitative methods to the study of pathologic specimens, providing a most timely renovation of morphologic pathology. This book will be of value to pulmonologists, physiologists, and researchers who are interested in lung morphometry.
Book Synopsis Particulate Discrete Element Modelling by : Catherine O'Sullivan
Download or read book Particulate Discrete Element Modelling written by Catherine O'Sullivan and published by CRC Press. This book was released on 2011-04-06 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first single work on DEM providing the information to get started with this powerful numerical modelling approach. Provides the basic details of the numerical method and the approaches used to interpret the results of DEM simulations. It will be of use to professionals, researchers and higher level students, with a theoretical overview of DEM as well as practical guidance.Selected Contents: 1.Introduction 2.Use of DEM in Geomechanics 3.Calculation of Contact Forces 4.Particle Motion 5.Particle Types 6.Boundary Conditions 7.Initial Geometry and Specimen Generation 8.Time Integration and Discrete Element Modelling 9.DEM Interpretation: A Continuum Perspective 10.Postprocessing: Graphical Interpretation of DEM Simulations 11.Basic Statisti
Book Synopsis The Mechanics of Inhaled Pharmaceutical Aerosols by : Warren H. Finlay
Download or read book The Mechanics of Inhaled Pharmaceutical Aerosols written by Warren H. Finlay and published by Academic Press. This book was released on 2001-07-06 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Mechanics of Inhaled Pharmaceutical Aerosols, An Introduction provides a unique and comprehensive treatment of the mechanics of inhaled pharmaceutical aerosols. The book covers a wide range of topics and many new perspectives are given by drawing on research from a variety of fields. Novel, in-depth expositions of the most common delivery devices are given, including nebulizers, dry powder inhalers and propellant metered dose inhalers. The behaviour of aerosols in the respiratory tract is explained in detail, with complete coverage of the fundamentals of current deposition models. The book begins by providing a comprehensive introduction to aspects of aerosol mechanics that are relevant to inhaled pharmaceutical aerosols. It then gives an exhaustive pedagogical description of the behaviour of evaporating and condensing droplets (both aqueous and propellant-based), an introductory chapter on lung geometry and inhalation patterns, and coverage of relevant aspects of fluid mechanics in the lung. Finally, the book provides invaluable, detailed coverage on the mechanics of common pharmaceutical aerosol delivery systems and deposition in the respiratory tract. Throughout the book are many detailed numerical examples that apply the salient concepts to typical inhaled pharmaceutical aerosols. This book will be of interest to scientists and engineers involved in the research and development of inhaled pharmaceutical aerosol products. Experienced practitioners will find many new perspectives that will greatly enhance their understanding of this complex and rapidly growing field. For those delivering therapeutic agents to the lung, this book is a must-have. Students and academics will find this book an invaluable tool and for newcomers it is a worthy guide to the diverse fields that must be understood to work in the area of inhaled pharmaceutical aerosols.
Book Synopsis Analytical Assessment of e-Cigarettes by : Konstantinos E. Farsalinos
Download or read book Analytical Assessment of e-Cigarettes written by Konstantinos E. Farsalinos and published by Elsevier. This book was released on 2016-11-16 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: A volume in the Emerging Issues in Analytical Chemistry series, Analytical Assessment of E-Cigarettes: From Contents to Chemical and Particle Exposure Profiles addresses the many issues surrounding electronic cigarettes in an unprecedented level of scientific detail. The plethora of product devices, formulations, and flavors, combined with the lack of industry standards and labeling requirements, quality control, and limited product oversight, has given rise to public concern about initiation of use and potential for adverse exposure and negative long-term health outcomes. This volume discusses how analytical methods can address these issues and support the manufacturing, labeling, distribution, testing, regulation, and monitoring for consistency of products with known chemical content and demonstrated performance characteristics. The book begins with the background on aerosol drug delivery services and e-cigarettes, constituents of nicotine-containing liquid dosing formulations, typical use scenarios and associated aerosol emissions, and chemical exposures and pharmacological and toxicological effect profiles, and then continues with descriptions of the analytical methods used to characterize the chemicals in formulations and emissions from e-cigarettes, including their stability, physical particle-size distribution and thermal degradation under commonly employed conditions of use. Analytical methods enabling detection of biomarkers of exposure and harm in complex biological matrices are discussed, with an emphasis on constituents or emissions of current medicinal interest or with potential to produce harm. Opportunities and challenges for analytical chemistry in supporting the continued development and use of safe and consistent dosage formulations as alternatives to tobacco products are also explored, with a concluding section describing an analytical approach to a risk-benefit assessment of e-cigarette use on human health. The Emerging Issues in Analytical Chemistry series is published in partnership with RTI International and edited by Brian F. Thomas. Please be sure to check out our other featured volumes: Thomas, Brian F. and ElSohly, Mahmoud. The Analytical Chemistry of Cannabis: Quality Assessment, Assurance, and Regulation of Medicinal Marijuana and Cannabinoid Preparations, 9780128046463, December 2015. Hackney, Anthony C. Exercise, Sport, and Bioanalytical Chemistry: Principles and Practice, 9780128092064, March 2016.Tanna, Sangeeta and Lawson, Graham. Analytical Chemistry for Assessing Medication Adherence, 9780128054635, April 2016.Rao, Vikram; Knight, Rob; and Stoner, Brian. Sustainable Shale Oil and Gas: Analytical Chemistry, Biochemistry, and Geochemistry Methods, 9780128103890, September 2016. - Discusses the chemistry and physics involved in aerosol production, inhalation, deposition, chemical exposure, and effect assessment - Contains current information and state-of-the-science methods on e-cigarette emissions, exposures, and harm assessment - Offers an authoritative, objective perspective from five of the most well-recognized scientists in their areas of expertise who have no personal stake in the e-cigarette industry or the opposition - Includes a foreword written by Dr. Neal Benowitz
Book Synopsis Advances in Pulmonary Drug Delivery by : Philip Chi Lip Kwok
Download or read book Advances in Pulmonary Drug Delivery written by Philip Chi Lip Kwok and published by CRC Press. This book was released on 2016-12-19 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: The respiratory tract has been used to deliver biologically active chemicals into the human body for centuries. However, the lungs are complex in their anatomy and physiology, which poses challenges to drug delivery. Inhaled formulations are generally more sophisticated than those for oral and parenteral administration. Pulmonary drug development is therefore a highly specialized area because of its many unique issues and challenges. Rapid progress is being made and offers novel solutions to existing treatment problems. Advances in Pulmonary Drug Delivery highlights the latest developments in this field.
Book Synopsis Aerosol Technology by : William C. Hinds
Download or read book Aerosol Technology written by William C. Hinds and published by John Wiley & Sons. This book was released on 2012-12-06 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: The #1 guide to aerosol science and technology -now better than ever Since 1982, Aerosol Technology has been the text of choice among students and professionals who need to acquire a thorough working knowledge of modern aerosol theory and applications. Now revised to reflect the considerable advances that have been made over the past seventeen years across a broad spectrum of aerosol-related application areas - from occupational hygiene and biomedical technology to microelectronics and pollution control -this new edition includes: * A chapter on bioaerosols * New sections on resuspension, transport losses, respiratory deposition models, and fractal characterization of particles * Expanded coverage of atmospheric aerosols, including background aerosols and urban aerosols * A section on the impact of aerosols on global warming and ozone depletion. Aerosol Technology, Second Edition also features dozens of new, fully worked examples drawn from a wide range of industrial and research settings, plus new chapter-end practice problems to help readers master the material quickly.
Book Synopsis Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems by : Kamal Dua
Download or read book Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems written by Kamal Dua and published by Academic Press. This book was released on 2020-08-04 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems explores the development of novel therapeutics and diagnostics to improve pulmonary disease management, looking down to the nanoscale level for an efficient system of targeting and managing respiratory disease. The book examines numerous nanoparticle-based drug systems such as nanocrystals, dendrimers, polymeric micelles, protein-based, carbon nanotube, and liposomes that can offer advantages over traditional drug delivery systems. Starting with a brief introduction on different types of nanoparticles in respiratory disease conditions, the book then focuses on current trends in disease pathology that use different in vitro and in vivo models. The comprehensive resource is designed for those new to the field and to specialized scientists and researchers involved in pulmonary research and drug development. - Explores recent perspectives and challenges regarding the management and diagnosis of chronic respiratory diseases - Provides insights into how advanced drug delivery systems can be effectively formulated and delivered for the management of various pulmonary diseases - Includes the most recent information on diagnostic methods and treatment strategies using controlled drug delivery systems (including nanotechnology)
