Compound Solutions

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Publisher :
ISBN 13 : 9781517900786
Total Pages : 0 pages
Book Rating : 4.9/5 (7 download)

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Book Synopsis Compound Solutions by : Susan Craddock

Download or read book Compound Solutions written by Susan Craddock and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Claiming 1.5 million lives in 2015, tuberculosis is the world's most deadly infectious disease. Because of the population it overwhelmingly affects, however, pharmaceutical companies are uninterested in developing better drugs for the disease. Compound Solutions examines Product Development Partnerships (PDPs), which arose early in the twenty-first century to develop new drugs and vaccines for infectious diseases in low-income countries. Here, for the first time, is a sustained examination of PDPs: the work they do, the partnerships they form, their mission, and their underlying philosophy of addressing global health needs--with implications that extend well beyond tuberculosis. Focusing on two PDPs for tuberculosis--the Global Alliance for TB Drug Development (TB Alliance) and Aeras (a nonprofit focused on vaccine development)--Susan Craddock argues that PDPs do much more than product development. As innovative sites of humanitarian pharmaceutical production, they are contravening mainstream pharmaceutical production by tying drug and vaccine research to global health needs rather than shareholder demand. In largely untethering the profit incentive from pharmaceutical production, Craddock shows, PDPs exhibit more creative and efficient scientific practices, reshaping regulatory norms and implementing more ethical forms of clinical trials that enhance community engagement and capacity building. An unparalleled, interdisciplinary analysis of PDPs as politically, socially, scientifically, and economically innovative sites of pharmaceutical production, Compound Solutions is a must for readers in the fields of public health, science and technology studies, and medical social science.

Compound Solutions

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Publisher : U of Minnesota Press
ISBN 13 : 1452953783
Total Pages : 246 pages
Book Rating : 4.4/5 (529 download)

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Book Synopsis Compound Solutions by : Susan Craddock

Download or read book Compound Solutions written by Susan Craddock and published by U of Minnesota Press. This book was released on 2017-02-21 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Claiming 1.5 million lives in 2015, tuberculosis is the world’s most deadly infectious disease. Because of the population it overwhelmingly affects, however, pharmaceutical companies are uninterested in developing better drugs for the disease. Compound Solutions examines Product Development Partnerships (PDPs), which arose early in the twenty-first century to develop new drugs and vaccines for infectious diseases in low-income countries. Here, for the first time, is a sustained examination of PDPs: the work they do, the partnerships they form, their mission, and their underlying philosophy of addressing global health needs—with implications that extend well beyond tuberculosis. Focusing on two PDPs for tuberculosis—the Global Alliance for TB Drug Development (TB Alliance) and Aeras (a nonprofit focused on vaccine development)—Susan Craddock argues that PDPs do much more than product development. As innovative sites of humanitarian pharmaceutical production, they are contravening mainstream pharmaceutical production by tying drug and vaccine research to global health needs rather than shareholder demand. In largely untethering the profit incentive from pharmaceutical production, Craddock shows, PDPs exhibit more creative and efficient scientific practices, reshaping regulatory norms and implementing more ethical forms of clinical trials that enhance community engagement and capacity building. An unparalleled, interdisciplinary analysis of PDPs as politically, socially, scientifically, and economically innovative sites of pharmaceutical production, Compound Solutions is a must for readers in the fields of public health, science and technology studies, and medical social science.

Mixtures, Compounds & Solutions

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Publisher : Heinemann-Raintree Library
ISBN 13 : 9781410916778
Total Pages : 52 pages
Book Rating : 4.9/5 (167 download)

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Book Synopsis Mixtures, Compounds & Solutions by : Carol Baldwin

Download or read book Mixtures, Compounds & Solutions written by Carol Baldwin and published by Heinemann-Raintree Library. This book was released on 2005-05 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a short study of mixtures, compounds, and solutions, and describes the physical properties of matter, chemical properties and changes, properties of compounds, and much more.

The Art of Compounding

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Publisher :
ISBN 13 :
Total Pages : 504 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis The Art of Compounding by : Wilbur Lincoln Scoville

Download or read book The Art of Compounding written by Wilbur Lincoln Scoville and published by . This book was released on 1927 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drug Compounding And Manufacturing

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Author :
Publisher : Jeffrey Frank Jones
ISBN 13 :
Total Pages : 128 pages
Book Rating : 4./5 ( download)

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Book Synopsis Drug Compounding And Manufacturing by :

Download or read book Drug Compounding And Manufacturing written by and published by Jeffrey Frank Jones. This book was released on with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Methods for the Determination of Organic Compounds in Drinking Water

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Publisher :
ISBN 13 :
Total Pages : 576 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Methods for the Determination of Organic Compounds in Drinking Water by :

Download or read book Methods for the Determination of Organic Compounds in Drinking Water written by and published by . This book was released on 1995 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Exploiting Chemical Diversity for Drug Discovery

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Publisher : Royal Society of Chemistry
ISBN 13 : 1847552552
Total Pages : 444 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis Exploiting Chemical Diversity for Drug Discovery by : Paul A Bartlett

Download or read book Exploiting Chemical Diversity for Drug Discovery written by Paul A Bartlett and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conceptual and technological advances in chemistry and biology have transformed the drug discovery process. Evolutionary pressure among the diverse scientific and engineering disciplines that contribute to the identification of biologically active compounds has resulted in synergistic improvements at every step in the process. Exploiting Chemical Diversity for Drug Discovery encompasses the many components of this transformation and presents the current state-of-the-art of this critical endeavour. From the theoretical and operational considerations in generating a collection of compounds to screen, to the design and implementation of high-capacity and high-quality assays that provide the most useful biological information, this book provides a comprehensive overview of modern approaches to lead identification. Beginning with an introductory overview, subsequent chapters address topics that include the design of chemical libraries and methods for optimizing their diversity; automated and accelerated chemistry; high throughput assay design and detection techniques; and strategies for data analysis and property optimization. Written by experts in the field, both academic and industrial, and illustrated in full colour, this book provides an excellent overview for current practitioners and will also serve as a stimulating resource for future generations. Researchers in organic and medicinal chemistry, the biological and pharmacological sciences, as well as those interested in allied computational and engineering disciplines will value the comprehensive and up-to-date coverage.

Perception, Cognition, and Development

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Publisher : Psychology Press
ISBN 13 : 1317738136
Total Pages : 325 pages
Book Rating : 4.3/5 (177 download)

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Book Synopsis Perception, Cognition, and Development by : T. J. Tighe

Download or read book Perception, Cognition, and Development written by T. J. Tighe and published by Psychology Press. This book was released on 2019-01-22 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is based on a conference held at Dartmouth College’s Minary Conference Center in Holdemess, New Hampshire, June 4 -7 , 1981. The conference brought together a number of investigators whose separate lines of inquiry bear in significant ways on the relationships among perception, cognition, and development. The purpose was to consider interactions among these basic processes not only as a critical facet of the research programs of the participants but also as a central conceptual problem for current theoretical psychology. First published in 1983. Routledge is an imprint of Taylor & Francis, an informa company.

Deburring and Edge Finishing Handbook

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Publisher : Society of Manufacturing Engineers
ISBN 13 : 0872635015
Total Pages : 433 pages
Book Rating : 4.8/5 (726 download)

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Book Synopsis Deburring and Edge Finishing Handbook by : LaRoux K. Gillespie

Download or read book Deburring and Edge Finishing Handbook written by LaRoux K. Gillespie and published by Society of Manufacturing Engineers. This book was released on 1999 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by industry expert, LaRoux Gillespie, this handbook is the most comprehensive book on burr removal and the treatment of edges ever published. Armed with this in-depth guide to deburring technologies, any engineer involved with part manufacturing will quickly discover how to accurately identify and evaluate the most efficient and cost effective deburring option(s) for a specific application. This groundbreaking work details 100 internationally recognized deburring and edge finishing processes you can employ. It also offers you an extensive base of technical information on a vast array of tools, applications and procedures available. From burr prevention in the design phase to actual burr removal on the line, you will be better prepared to deal with burrs and edge defects and also determine what tolerance level is acceptable for quality production standards - before it becomes a shopfloor problem. Learn how to weigh aesthetic and functional justifications across a wide array of mechanical, thermal, chemical, electrical and manual techniques.

Design Computing and Cognition '08

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Publisher : Springer Science & Business Media
ISBN 13 : 1402087284
Total Pages : 734 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Design Computing and Cognition '08 by : John S. Gero

Download or read book Design Computing and Cognition '08 written by John S. Gero and published by Springer Science & Business Media. This book was released on 2008-09-27 with total page 734 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of research and education in design continues to grow. For example, government agencies are gradually increasing funding of design research, and increasing numbers of engineering schools are revising their curricula to emphasize design. This is because of an increasing realization that design is part of the wealth creation of a nation and needs to be better understood and taught. The continuing globalization of industry and trade has required nations to re-examine where their core contributions lie if not in production efficiency. Design is a precursor to manufacturing for phy- cal objects and is the precursor to implementation for virtual objects. At the same time, the need for sustainable development is requiring design of new products and processes, and feeding a movement towards design - novations and inventions. There are now three sources for design research: design computing, design cognition and human-centered information technology. The foun- tions for much of design computing remains artificial intelligence with its focus on ways of representation and on processes that support simulation and generation. Artificial intelligence continues to provide an environm- tally rich paradigm within which design research based on computational constructions can be carried out. Design cognition is founded on concepts from cognitive science, an even newer area than artificial intelligence. It provides tools and methods to study human designers in both laboratory and practice settings.

Drug Discovery

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Publisher : John Wiley & Sons
ISBN 13 : 1118354478
Total Pages : 595 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Drug Discovery by : Jie Jack Li

Download or read book Drug Discovery written by Jie Jack Li and published by John Wiley & Sons. This book was released on 2013-04-12 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sets forth the history, state of the science, and future directions of drug discovery Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leading pioneers in drug discovery and medicinal chemistry, this book synthesizes great moments in history, the current state of the science, and future directions of drug discovery into one expertly written and organized work. Exploring all major therapeutic areas, the book introduces readers to all facets and phases of drug discovery, including target selection, biological testing, drug metabolism, and computer-assisted drug design. Drug Discovery features chapters written by an international team of pharmaceutical and medicinal chemists. Contributions are based on a thorough review of the current literature as well as the authors' firsthand laboratory experience in drug discovery. The book begins with the history of drug discovery, describing groundbreaking moments in the field. Next, it covers such topics as: Target identification and validation Drug metabolism and pharmacokinetics Central nervous system drugs In vitro and in vivo assays Cardiovascular drugs Cancer drugs Each chapter features a case study, helping readers understand how science is put into practice throughout all phases of drug discovery. References at the end of each chapter serve as a gateway to groundbreaking original research studies and reviews in the field. Drug Discovery is ideal for newcomers to medicinal chemistry and drug discovery, providing a comprehensive overview of the field. Veterans in the field will also benefit from the perspectives of leading international experts in all aspects of drug discovery.

Physical Metallurgy and processing of Intermetallic Compounds

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Publisher : Springer Science & Business Media
ISBN 13 : 1461312159
Total Pages : 690 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Physical Metallurgy and processing of Intermetallic Compounds by : N.S. Stoloff

Download or read book Physical Metallurgy and processing of Intermetallic Compounds written by N.S. Stoloff and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: The attractive physical and mechanical properties of ordered intermetallic alloys have been recognized since early in this century. However, periodic attempts to develop intermetallics for structural applications were unsuc cessful, due in major part to the twin handicaps of inadequate low-temper ature ductility or toughness, together with poor elevated-temperature creep strength. The discovery, in 1979, by Aoki and Izumi in Japan that small additions of boron caused a dramatic improvement in the ductility of Ni3Al was a major factor in launching a new wave of fundamental and applied research on intermetallics. Another important factor was the issuance in 1984 of a National Materials Advisory Board reported entitled "Structural Uses for Ductile Ordered Alloys," which identified numerous potential defense-related applications and proposed the launching of a coordinated development program to gather engineering property and processing data. A substantial research effort on titanium aluminides was already underway at the Air Force Materials Laboratory at Wright Patterson Air Force Base in Ohio and, with Air Force support, at several industrial and university laboratories. Smaller programs also were under way at Oak Ridge National Laboratory, under Department of Energy sponsorship. These research efforts were soon augmented in the United States by funding from Department of Defense agencies such as Office of Naval Research and Air Force Office of Scientific Research, and by the National Science Foundation.

The Experimental Psychology of Mental Retardation

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Publisher : Routledge
ISBN 13 : 1351483064
Total Pages : 462 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis The Experimental Psychology of Mental Retardation by : Donald K. Routh

Download or read book The Experimental Psychology of Mental Retardation written by Donald K. Routh and published by Routledge. This book was released on 2017-07-05 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: The renaissance in the field of mental retardation since World War II has been expressed both in research and in renewed practical concern for the plight of the retarded. The 1958 monograph by Masland, Sarason, and Gladwin entitled Mental Subnormality: Biological, Psychological, and Cultural Factors was one spur, if not the only one, to much of the behavioral research which emerged in the late 1950's. Similarly, the Handbook of Mental Deficiency, edited by Norman Ellis and published in 1963, gave theoretical direction to many studies in the years following its appearance.The present book and the symposium on which it is based are an attempt to continue this tradition by presenting theory-based, programmatic research in mental retardation, aimed at the scientific understanding of the psychological processes involved. The final chapter attempts to draw some of the implications of this research for the practical assessment and remediation of retardation.The experimental work reported in this book generally uses rather traditional laboratory tasks, for example, classical conditioning or discrimination learning. But the interest is in underlying processes rather than in such apparent trivia as whether the child blinks his eyelid or which of two stimulus objects he selects. Thus, this book is oriented around the psychological processes of interest, namely learning, attention, memory, language, thinking, and emotion, and concludes with a section on the relationship between these processes and the biological aspects of retardation.

The Role of Affective Processes in Learning and Motivation

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Publisher : Ardent Media
ISBN 13 :
Total Pages : 24 pages
Book Rating : 4./5 ( download)

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Book Synopsis The Role of Affective Processes in Learning and Motivation by :

Download or read book The Role of Affective Processes in Learning and Motivation written by and published by Ardent Media. This book was released on with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Label-Free Biosensors

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Publisher : Cambridge University Press
ISBN 13 : 1139476785
Total Pages : 305 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Label-Free Biosensors by : Matthew A. Cooper

Download or read book Label-Free Biosensors written by Matthew A. Cooper and published by Cambridge University Press. This book was released on 2009-02-02 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Label-free biosensors are devices that use biological or chemical receptors to detect analytes (molecules) in a sample. They give detailed information on the selectivity, affinity, and, in many cases, also the binding kinetics and thermodynamics of an interaction. Although they can be powerful tools in the hands of a skilled user, there is often a lack of knowledge of the best methods for using label-free assays to screen for biologically active molecules and accurately and precisely characterize molecular recognition events. This book reviews both established and newer label-free techniques giving both the expert user and the general reader interested in the technologies and applications behind label-free an insight into the field from expert opinion leaders and practitioners of the technologies. Most importantly, chapters contain worked examples from leaders in the field that take the reader through the basics of experimental design, setup, assay development, and data analysis.

Case-Based Reasoning Research and Development

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540605980
Total Pages : 596 pages
Book Rating : 4.6/5 (59 download)

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Book Synopsis Case-Based Reasoning Research and Development by : Manuela Veloso

Download or read book Case-Based Reasoning Research and Development written by Manuela Veloso and published by Springer Science & Business Media. This book was released on 1995-10-16 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the First International Conference on Case-Based Reasoning, ICCBR-95, held in Sesimbra, Portugal, in October 1995. The 52 revised papers included are classified as scientific papers , application papers , and posters . All current aspects of research and development aiming at industrial applications in CBR are addressed. Among the topical sections are case and knowledge representation, case retrieval, nearest neighbour methods, case adaption and learning, cognitive modelling, integrated reasoning methods, and application-oriented methods: planning, decision making, diagnosis, interpretation, design, etc.

Management of Chemical and Biological Samples for Screening Applications

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Publisher : John Wiley & Sons
ISBN 13 : 3527645268
Total Pages : 435 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Management of Chemical and Biological Samples for Screening Applications by : Mark Wigglesworth

Download or read book Management of Chemical and Biological Samples for Screening Applications written by Mark Wigglesworth and published by John Wiley & Sons. This book was released on 2012-12-05 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Filling an obvious gap in the scientific literature, this practice-oriented reference is the first to tie together the working knowledge of large screening centers in the pharmaceutical and biotechnological field. It spans the entire fi eld of this emerging discipline, from compound acquisition to collection optimization for specific purposes, to technology and quality control. In so doing, it applies two decades of expertise gathered by several large pharmaceutical companies to current and future challenges in high-throughput screening. With its treatment of libraries of small molecules as well as biobanks containing biomolecules, microorganisms and tissue samples, this reference is universally applicable for any molecular scientist involved in a large screening program.